BR9607775A - Novos compostos farmacêuticos de benzotiofeno - Google Patents
Novos compostos farmacêuticos de benzotiofenoInfo
- Publication number
- BR9607775A BR9607775A BR9607775A BR9607775A BR9607775A BR 9607775 A BR9607775 A BR 9607775A BR 9607775 A BR9607775 A BR 9607775A BR 9607775 A BR9607775 A BR 9607775A BR 9607775 A BR9607775 A BR 9607775A
- Authority
- BR
- Brazil
- Prior art keywords
- alkyl
- rdurule
- aryl
- compounds
- progestin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/56—Radicals substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/402,415 US6395755B1 (en) | 1995-03-10 | 1995-03-10 | Benzothiophene pharmaceutical compounds |
| PCT/US1996/003164 WO1996028155A1 (en) | 1995-03-10 | 1996-03-07 | Novel benzothiophene pharmaceutical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9607775A true BR9607775A (pt) | 1998-07-07 |
Family
ID=23591799
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9607775A BR9607775A (pt) | 1995-03-10 | 1996-03-07 | Novos compostos farmacêuticos de benzotiofeno |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6395755B1 (pt) |
| EP (2) | EP0731100B1 (pt) |
| JP (1) | JPH11501930A (pt) |
| AT (2) | ATE247100T1 (pt) |
| AU (1) | AU697502B2 (pt) |
| BR (1) | BR9607775A (pt) |
| CA (1) | CA2214261A1 (pt) |
| DE (2) | DE69609748T2 (pt) |
| DK (1) | DK0731100T3 (pt) |
| ES (2) | ES2205702T3 (pt) |
| GR (1) | GR3034762T3 (pt) |
| IL (1) | IL117398A (pt) |
| PT (1) | PT731100E (pt) |
| SI (1) | SI0731100T1 (pt) |
| WO (1) | WO1996028155A1 (pt) |
| ZA (1) | ZA961883B (pt) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6432982B1 (en) * | 1996-02-21 | 2002-08-13 | Eli Lilly And Company | Benzothiophenes, and formulations and methods using same |
| EP0801066A1 (en) * | 1996-03-12 | 1997-10-15 | Eli Lilly And Company | Heterocyclic substituted benzothiophenes and pharmaceutical compositions |
| CA2214072C (en) * | 1996-08-29 | 2006-11-14 | Eli Lilly And Company | Benzo [b] thiophene compounds, intermediates, processes, compositions, and methods |
| CA2214196A1 (en) * | 1996-09-26 | 1998-03-26 | Eli Lilly And Company | Benzo[b]indeno[2,1-d]thiophene compounds, intermediates, processes, compositions and methods |
| CA2216592C (en) * | 1996-10-24 | 2006-07-18 | Brian Stephen Muehl | Benzothiophene compounds, intermediates, compositions, and methods |
| WO2002094788A1 (en) | 2001-05-22 | 2002-11-28 | Eli Lilly And Company | 2-substituted 1,2,3,4-tetrahydroquinolines and derivatives thereof, compositions and methods |
| JP2004531559A (ja) | 2001-05-22 | 2004-10-14 | イーライ・リリー・アンド・カンパニー | エストロゲン欠乏または内因性エストロゲンに対する異常な生理反応に関連する疾患を抑制するためのテトラヒドロキノリン誘導体 |
| CN1599606A (zh) | 2001-07-31 | 2005-03-23 | 辉瑞产品公司 | 包含雌激素激动剂/拮抗剂、雌激素与孕激素组合的药物组合物、试剂盒和方法 |
| DE602005017577D1 (de) * | 2004-01-22 | 2009-12-24 | Lilly Co Eli | Selektive östrogen-rezeptor-modulatoren |
| GR1005694B (el) * | 2005-06-08 | 2007-10-22 | Αλεξης Μιχαηλ | Ιστοειδικα αντιοιστρογονα ειδικα για τον αλφα υποδοχεα των οιστρογονων |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1300575B (de) * | 1965-05-21 | 1969-08-07 | Bristol Myers Co | Benzo[b]thiophene |
| US3947470A (en) | 1974-06-20 | 1976-03-30 | Smithkline Corporation | Substituted benzofurans and benzothiophenes |
| US4133814A (en) * | 1975-10-28 | 1979-01-09 | Eli Lilly And Company | 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents |
| IT1154888B (it) * | 1980-11-12 | 1987-01-21 | Menarini Sas | Derivati del benzofurano 2-sostituiti e relativi metodi di preparazione |
| IL65379A0 (en) * | 1981-04-03 | 1982-05-31 | Lilly Co Eli | Process for preparing acylated benzothiophenes |
| AU555658B2 (en) * | 1981-04-03 | 1986-10-02 | Eli Lilly And Company | Benzothiophene compounds |
| US4380635A (en) | 1981-04-03 | 1983-04-19 | Eli Lilly And Company | Synthesis of acylated benzothiophenes |
| US4418068A (en) * | 1981-04-03 | 1983-11-29 | Eli Lilly And Company | Antiestrogenic and antiandrugenic benzothiophenes |
| US4851554A (en) | 1987-04-06 | 1989-07-25 | University Of Tennessee Research Corporation | Certain 3-substituted 2-alkyl benzofuran derivatives |
| WO1989002893A1 (en) * | 1987-09-30 | 1989-04-06 | The University Of Tennessee Research Corporation | Certain 3-substituted 2-alkyl benzothiophene derivatives |
| US5395842A (en) * | 1988-10-31 | 1995-03-07 | Endorecherche Inc. | Anti-estrogenic compounds and compositions |
| FR2665444B1 (fr) * | 1990-08-06 | 1992-11-27 | Sanofi Sa | Derives d'amino-benzofuranne, benzothiophene ou indole, leur procede de preparation ainsi que les compositions les contenant. |
| DE4117512A1 (de) * | 1991-05-25 | 1992-11-26 | Schering Ag | 2-phenylbenzo(b)furane und -thiophene, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate |
| JP3157882B2 (ja) * | 1991-11-15 | 2001-04-16 | 帝国臓器製薬株式会社 | 新規なベンゾチオフエン誘導体 |
| TW366342B (en) | 1992-07-28 | 1999-08-11 | Lilly Co Eli | The use of 2-phenyl-3-aroylbenzothiophenes in inhibiting bone loss |
| US5482949A (en) | 1993-03-19 | 1996-01-09 | Eli Lilly And Company | Sulfonate derivatives of 3-aroylbenzo[b]thiophenes |
| US6756388B1 (en) * | 1993-10-12 | 2004-06-29 | Pfizer Inc. | Benzothiophenes and related compounds as estrogen agonists |
| US5523309A (en) * | 1995-03-10 | 1996-06-04 | Eli Lilly And Company | Benzofuran pharmaceutical compounds |
-
1995
- 1995-03-10 US US08/402,415 patent/US6395755B1/en not_active Expired - Fee Related
-
1996
- 1996-03-06 DE DE69609748T patent/DE69609748T2/de not_active Expired - Fee Related
- 1996-03-06 SI SI9630256T patent/SI0731100T1/xx unknown
- 1996-03-06 AT AT99202800T patent/ATE247100T1/de not_active IP Right Cessation
- 1996-03-06 EP EP96301534A patent/EP0731100B1/en not_active Expired - Lifetime
- 1996-03-06 ES ES99202800T patent/ES2205702T3/es not_active Expired - Lifetime
- 1996-03-06 ES ES96301534T patent/ES2148681T3/es not_active Expired - Lifetime
- 1996-03-06 DE DE69629500T patent/DE69629500T2/de not_active Expired - Fee Related
- 1996-03-06 PT PT96301534T patent/PT731100E/pt unknown
- 1996-03-06 DK DK96301534T patent/DK0731100T3/da active
- 1996-03-06 AT AT96301534T patent/ATE195519T1/de not_active IP Right Cessation
- 1996-03-06 EP EP99202800A patent/EP0953568B1/en not_active Expired - Lifetime
- 1996-03-07 WO PCT/US1996/003164 patent/WO1996028155A1/en active Application Filing
- 1996-03-07 CA CA002214261A patent/CA2214261A1/en not_active Abandoned
- 1996-03-07 IL IL11739896A patent/IL117398A/xx not_active IP Right Cessation
- 1996-03-07 AU AU53048/96A patent/AU697502B2/en not_active Ceased
- 1996-03-07 ZA ZA9601883A patent/ZA961883B/xx unknown
- 1996-03-07 BR BR9607775A patent/BR9607775A/pt not_active Application Discontinuation
- 1996-03-07 JP JP8527729A patent/JPH11501930A/ja active Pending
-
2000
- 2000-11-07 GR GR20000402451T patent/GR3034762T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| MX9706737A (es) | 1997-11-29 |
| US6395755B1 (en) | 2002-05-28 |
| WO1996028155A1 (en) | 1996-09-19 |
| IL117398A (en) | 2000-11-21 |
| PT731100E (pt) | 2001-01-31 |
| EP0731100A1 (en) | 1996-09-11 |
| CA2214261A1 (en) | 1996-09-19 |
| DK0731100T3 (da) | 2000-09-18 |
| ZA961883B (en) | 1997-09-08 |
| ATE247100T1 (de) | 2003-08-15 |
| EP0953568B1 (en) | 2003-08-13 |
| DE69629500D1 (de) | 2003-09-18 |
| AU5304896A (en) | 1996-10-02 |
| EP0731100B1 (en) | 2000-08-16 |
| GR3034762T3 (en) | 2001-02-28 |
| SI0731100T1 (en) | 2001-02-28 |
| ATE195519T1 (de) | 2000-09-15 |
| DE69609748D1 (de) | 2000-09-21 |
| EP0953568A1 (en) | 1999-11-03 |
| ES2148681T3 (es) | 2000-10-16 |
| DE69629500T2 (de) | 2004-07-01 |
| DE69609748T2 (de) | 2001-04-12 |
| IL117398A0 (en) | 1996-07-23 |
| JPH11501930A (ja) | 1999-02-16 |
| AU697502B2 (en) | 1998-10-08 |
| ES2205702T3 (es) | 2004-05-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2228997A1 (en) | Benzothiophene compounds | |
| ZA957857B (en) | Naphtyl compounds intermediates processes compositions and methods | |
| AU692690B2 (en) | Novel benzofuran pharmaceutical compounds useful for alleviating the symptoms of post menopausal syndrome | |
| BR9607775A (pt) | Novos compostos farmacêuticos de benzotiofeno | |
| ES464504A1 (es) | Un procedimiento para la preparacion de nuevos esteres de esteroides. | |
| PL324816A1 (en) | Naphtylic and dihydronaphtylic intermediatew compounds, compounds, agents and associated compounds | |
| EP0774966A4 (en) | BENZOFURANE COMPOUNDS, PREPARATIONS AND METHODS | |
| AR007012A1 (es) | Compuestos de 2-fenil-3-benzoil-benzotiofenos, composiciones farmaceuticas que los contienen y el uso de dichos compuestos para el tratamiento del sindrome postmenopausico, inhibicion del cancer estrogenodependiente, entre otras afecciones patologicas | |
| MX9706741A (es) | Compuestos farmaceuticos novedosos de naftilo. | |
| NZ334184A (en) | Naphthyl compounds, intermediates, compositions for the prevention of bone loss or bone resorption and lower cholesterol | |
| EP0827959A3 (en) | Benzo[B]thiophene compounds, intermediates, processes, compositions, and methods |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA8 | Dismissal: dismissal - article 36, par. 1 of industrial property law |