BR9408335A - Composto uso do mesmo e composição farmacêutica - Google Patents

Composto uso do mesmo e composição farmacêutica

Info

Publication number
BR9408335A
BR9408335A BR9408335A BR9408335A BR9408335A BR 9408335 A BR9408335 A BR 9408335A BR 9408335 A BR9408335 A BR 9408335A BR 9408335 A BR9408335 A BR 9408335A BR 9408335 A BR9408335 A BR 9408335A
Authority
BR
Brazil
Prior art keywords
unsubstituted
alkanyl
alkenyl
compounds
same
Prior art date
Application number
BR9408335A
Other languages
English (en)
Inventor
Thomas Lee Cupps
Peter Julian Muerer
Jeffrey Joseph Ares
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/326,564 external-priority patent/US5578607A/en
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of BR9408335A publication Critical patent/BR9408335A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
BR9408335A 1993-12-17 1994-12-15 Composto uso do mesmo e composição farmacêutica BR9408335A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16934393A 1993-12-17 1993-12-17
US08/326,564 US5578607A (en) 1993-12-17 1994-10-20 6-(2-imidazolinylamino)quinoline compounds useful as alpha-2 adrenoceptor agonists
PCT/US1994/014293 WO1995016683A1 (en) 1993-12-17 1994-12-15 6-(2-imidazolinylamino)quinoline compounds useful as alpha-2 adrenoceptor agonists

Publications (1)

Publication Number Publication Date
BR9408335A true BR9408335A (pt) 1997-08-19

Family

ID=26864975

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9408335A BR9408335A (pt) 1993-12-17 1994-12-15 Composto uso do mesmo e composição farmacêutica

Country Status (23)

Country Link
US (1) US5739148A (pt)
EP (1) EP0736020B1 (pt)
JP (1) JPH09511483A (pt)
CN (1) CN1046718C (pt)
AT (1) ATE192150T1 (pt)
AU (1) AU699041B2 (pt)
BR (1) BR9408335A (pt)
CA (1) CA2179264C (pt)
CZ (1) CZ285481B6 (pt)
DE (1) DE69424183T2 (pt)
DK (1) DK0736020T3 (pt)
ES (1) ES2146307T3 (pt)
FI (1) FI962491A (pt)
GR (1) GR3033515T3 (pt)
HK (1) HK1013072A1 (pt)
HU (1) HU217841B (pt)
NO (1) NO308662B1 (pt)
NZ (1) NZ333370A (pt)
PL (1) PL180392B1 (pt)
PT (1) PT736020E (pt)
SG (1) SG55141A1 (pt)
SK (1) SK77096A3 (pt)
WO (1) WO1995016683A1 (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW527355B (en) 1997-07-02 2003-04-11 Bristol Myers Squibb Co Inhibitors of farnesyl protein transferase
US20070293539A1 (en) * 2004-03-18 2007-12-20 Lansbury Peter T Methods for the treatment of synucleinopathies
WO2005089515A2 (en) * 2004-03-18 2005-09-29 The Brigham And Women's Hospital, Inc. Methods for the treatment of synucleinopathies
JP2007538004A (ja) * 2004-03-18 2007-12-27 ザ ブライハム アンド ウイメンズ ホスピタル， インコーポレイテッド シヌクレイノパチーを治療する方法
CA2559285A1 (en) * 2004-03-18 2005-09-29 Brigham And Women's Hospital, Inc. Methods for the treatment of synucleinopathies
CA2559282A1 (en) * 2004-03-18 2005-09-29 Brigham And Women's Hospital, Inc. Methods for the treatment of synucleinopathies
CA2562713A1 (en) * 2004-04-14 2005-12-15 Gilead Sciences, Inc. Phosphonate analogs of hiv integrase inhibitor compounds
NZ568694A (en) 2005-11-09 2011-09-30 Zalicus Inc Method, compositions, and kits for the treatment of medical conditions
US8232402B2 (en) * 2008-03-12 2012-07-31 Link Medicine Corporation Quinolinone farnesyl transferase inhibitors for the treatment of synucleinopathies and other indications
BRPI0920927A2 (pt) * 2008-11-13 2019-09-24 Link Medicine Corp derivados de azaquinolinona e usos dos mesmos
US20100331363A1 (en) * 2008-11-13 2010-12-30 Link Medicine Corporation Treatment of mitochondrial disorders using a farnesyl transferase inhibitor
US20110060005A1 (en) * 2008-11-13 2011-03-10 Link Medicine Corporation Treatment of mitochondrial disorders using a farnesyl transferase inhibitor
CA2843251A1 (en) * 2011-07-25 2013-01-31 Santosh C. Sinha N-(imidazolidin-2-ylidene)quinoline derivatives as modulators of alpha 2 adrenergic receptors

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE795970A (fr) * 1972-02-29 1973-08-27 Pfizer Nouveaux derives de quinoleine, quinoxaline et quinazoline er composition pharmaceutiques les contenant
US4029792A (en) * 1972-02-29 1977-06-14 Pfizer Inc. (2-Imidazolin-2-ylamino) substituted -quinoxalines and -quinazolines as antihypertensive agents
US4036976A (en) * 1973-04-05 1977-07-19 Sandoz, Inc. Substituted imidazolinylamino-indazoles
US4217356A (en) * 1975-08-22 1980-08-12 Sandoz Ltd. 2-Imidazolinylamino-2,1,3-benzothiadiazoles
US4398028A (en) * 1977-01-14 1983-08-09 Sandoz Ltd. Bicyclic heterocyclic amino derivatives
EP0025269B1 (en) * 1979-08-23 1985-11-13 Beecham Group Plc Anti-diarrhoea veterinary composition
US4436913A (en) * 1980-09-05 1984-03-13 Siegfried Aktiengesellschaft 1H- and 2H- indazole derivatives
FR2638356A1 (fr) * 1988-10-28 1990-05-04 Anben Nouveaux derives de la 2-arylimino-imidazolidine pour diminuer la pression intra-oculaire et traiter le glaucome
US5180721A (en) * 1989-05-22 1993-01-19 Allergan, Inc. Combinations of selective alpha-adrenergic agonists and antagonists useful in lowering intraocular pressure
US5021410A (en) * 1989-05-22 1991-06-04 Allergan, Inc. Combinations of selective alpha-adrenergic agonists and antagonists useful in lowering intraocular pressure
US5281591A (en) * 1989-05-22 1994-01-25 Allergan, Inc. Combinations of selective alpha-adrenergic agonists and antagonists useful in lowering intraocular pressure
US5231096A (en) * 1989-10-12 1993-07-27 Allergan, Inc. Methods for using (2-imidazolin-2-ylamino) quinoxaline derivatives
US5021416A (en) * 1989-10-31 1991-06-04 Allergan, Inc. Method for using (2-imidazolin-2-ylamino) quinoxalines to reduce or maintain intraocular pressure
US5091528A (en) * 1990-09-12 1992-02-25 Allergan, Inc. 6- or 7- (2-imino-2-imidazolidine)-1,4-benzoxazines as α adrenergic agents

Also Published As

Publication number Publication date
EP0736020B1 (en) 2000-04-26
AU699041B2 (en) 1998-11-19
JPH09511483A (ja) 1997-11-18
HUT76277A (en) 1997-07-28
CN1046718C (zh) 1999-11-24
FI962491A (fi) 1996-07-26
CN1137793A (zh) 1996-12-11
NO962536D0 (no) 1996-06-14
EP0736020A1 (en) 1996-10-09
HU9601659D0 (en) 1996-08-28
PL315060A1 (en) 1996-09-30
CZ285481B6 (cs) 1999-08-11
ES2146307T3 (es) 2000-08-01
PT736020E (pt) 2000-10-31
NO962536L (no) 1996-08-02
HK1013072A1 (en) 1999-08-13
WO1995016683A1 (en) 1995-06-22
AU1306395A (en) 1995-07-03
ATE192150T1 (de) 2000-05-15
CA2179264A1 (en) 1995-06-22
CA2179264C (en) 1999-05-18
FI962491A0 (fi) 1996-06-14
PL180392B1 (pl) 2001-01-31
GR3033515T3 (en) 2000-09-29
DE69424183T2 (de) 2001-02-15
CZ175396A3 (en) 1996-11-13
SG55141A1 (en) 1998-12-21
HU217841B (hu) 2000-04-28
DE69424183D1 (de) 2000-05-31
NO308662B1 (no) 2000-10-09
SK77096A3 (en) 1997-02-05
DK0736020T3 (da) 2000-08-07
NZ333370A (en) 2001-03-30
US5739148A (en) 1998-04-14

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Legal Events

Date Code Title Description
EG Technical examination (opinion): publication of technical examination (opinion)
FC Decision: refusal
CKFC Appeal: appeal against refusal