BR9305674A - Nabumetone endurecido por spray - Google Patents

Nabumetone endurecido por spray

Info

Publication number
BR9305674A
BR9305674A BR9305674-5A BR9305674A BR9305674A BR 9305674 A BR9305674 A BR 9305674A BR 9305674 A BR9305674 A BR 9305674A BR 9305674 A BR9305674 A BR 9305674A
Authority
BR
Brazil
Prior art keywords
pct
nabumetone
spray
sec
hardened
Prior art date
Application number
BR9305674-5A
Other languages
English (en)
Inventor
Graham Stanley Leonard
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of BR9305674A publication Critical patent/BR9305674A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/255—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coating By Spraying Or Casting (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Freezing, Cooling And Drying Of Foods (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Road Signs Or Road Markings (AREA)
  • Catching Or Destruction (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

"NABUMETONE ENDURECIDO POR SPRAY". Trata-se de nabumetone que é endurecido por spray na forma de dose unitária com volume menor do que os já existentes facilitando a ingestão.
BR9305674-5A 1992-01-29 1993-01-22 Nabumetone endurecido por spray BR9305674A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929201857A GB9201857D0 (en) 1992-01-29 1992-01-29 Novel compound
PCT/GB1993/000145 WO1993014747A1 (en) 1992-01-29 1993-01-22 Spray-chilled nabumetone

Publications (1)

Publication Number Publication Date
BR9305674A true BR9305674A (pt) 2005-01-11

Family

ID=10709436

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9305674-5A BR9305674A (pt) 1992-01-29 1993-01-22 Nabumetone endurecido por spray

Country Status (24)

Country Link
US (1) US5539000A (pt)
EP (1) EP0624087B1 (pt)
JP (1) JPH07503245A (pt)
KR (1) KR950700056A (pt)
CN (1) CN1079954A (pt)
AT (1) ATE150298T1 (pt)
AU (1) AU3362693A (pt)
BG (1) BG98933A (pt)
BR (1) BR9305674A (pt)
CA (1) CA2129027A1 (pt)
CZ (1) CZ182894A3 (pt)
DE (1) DE69309037T2 (pt)
DK (1) DK0624087T3 (pt)
ES (1) ES2099419T3 (pt)
FI (1) FI943550A (pt)
GB (1) GB9201857D0 (pt)
GR (1) GR3023142T3 (pt)
HU (1) HUT67462A (pt)
IL (1) IL104526A0 (pt)
MX (1) MX9300430A (pt)
NO (1) NO942813D0 (pt)
SK (1) SK91694A3 (pt)
WO (1) WO1993014747A1 (pt)
ZA (1) ZA93577B (pt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030236236A1 (en) * 1999-06-30 2003-12-25 Feng-Jing Chen Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs
GB9920148D0 (en) * 1999-08-25 1999-10-27 Smithkline Beecham Plc Novel composition
US6436990B1 (en) 1999-10-27 2002-08-20 Nobex Corporation 6-methoxy-2-naphthylacetic acid prodrugs
US6552078B2 (en) 1999-10-27 2003-04-22 Nobex Corp 6-methoxy-2-naphthylacetic acid prodrugs
TWI262791B (en) 1999-10-27 2006-10-01 Nobex Corp 6-methoxy-2-naphthylacetic acid prodrugs
US20020132010A1 (en) * 2000-12-22 2002-09-19 Yihong Qui Divalproex sodium dosage forms and a process for their production
US20040161474A1 (en) * 2002-05-24 2004-08-19 Moerck Rudi E. Rare earth metal compounds methods of making, and methods of using the same
US20060083791A1 (en) 2002-05-24 2006-04-20 Moerck Rudi E Rare earth metal compounds methods of making, and methods of using the same
US20040115287A1 (en) * 2002-12-17 2004-06-17 Lipocine, Inc. Hydrophobic active agent compositions and methods
CA2547597A1 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Multiparticulate compositions with improved stability
BRPI0417348A (pt) * 2003-12-04 2007-03-13 Pfizer Prod Inc processo de gelatinização por spray com utilização de uma extrusora para preparação de composições de droga cristalina multiparticulada contendo preferencialmente um poloxámero e um glicerìdeo
US6984403B2 (en) * 2003-12-04 2006-01-10 Pfizer Inc. Azithromycin dosage forms with reduced side effects
JP2007513143A (ja) * 2003-12-04 2007-05-24 ファイザー・プロダクツ・インク 押出機を使用して好ましくはポロクサマーおよびグリセリドを含む多粒子アジスロマイシン組成物を製造するための噴霧凝固法
ATE399536T1 (de) * 2003-12-04 2008-07-15 Pfizer Prod Inc Verfahren zur herstellung von pharmazeutischen multiteilchenförmigen produkten
WO2005053639A2 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Controlled release multiparticulates formed with dissolution enhancers
CA2547239A1 (en) * 2003-12-04 2005-06-16 Pfizer Products Inc. Azithromycin multiparticulate dosage forms by liquid-based processes
WO2005053652A1 (en) 2003-12-04 2005-06-16 Pfizer Products Inc. Multiparticulate crystalline drug compositions containing a poloxamer and a glyceride
CA2583548A1 (en) * 2004-10-15 2006-04-27 Altairnano, Inc. Phosphate binder with reduced pill burden
JP2009504779A (ja) * 2005-08-17 2009-02-05 アルテアナノ インコーポレイテッド 家畜における慢性腎不全及びその他の病気の治療：組成物及び方法
US8217083B2 (en) * 2007-06-08 2012-07-10 Aptalis Pharma Canada Inc. Mesalamine suppository
US7541384B2 (en) * 2007-06-08 2009-06-02 Axcan Pharma Inc. Mesalamine suppository
US8436051B2 (en) * 2007-06-08 2013-05-07 Aptalis Pharma Canada Inc. Mesalamine suppository
US11304960B2 (en) 2009-01-08 2022-04-19 Chandrashekar Giliyar Steroidal compositions
US8961917B2 (en) 2010-05-12 2015-02-24 Spectrum Pharmaceuticals, Inc. Lanthanum carbonate hydroxide, lanthanum oxycarbonate and methods of their manufacture and use
US20180153904A1 (en) 2010-11-30 2018-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US9358241B2 (en) 2010-11-30 2016-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US20120148675A1 (en) 2010-12-10 2012-06-14 Basawaraj Chickmath Testosterone undecanoate compositions
WO2016033556A1 (en) 2014-08-28 2016-03-03 Lipocine Inc. BIOAVAILABLE SOLID STATE (17-β)-HYDROXY-4-ANDROSTEN-3-ONE ESTERS
WO2016033549A2 (en) 2014-08-28 2016-03-03 Lipocine Inc. (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE
US20180147215A1 (en) 2016-11-28 2018-05-31 Lipocine Inc. Oral testosterone undecanoate therapy

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4420639C1 (en) * 1973-09-11 2001-08-21 Beecham Group Ltd Aromatic compounds
GB1474377A (en) 1973-09-11 1977-05-25 Beecham Group Ltd Naphthalene derivatives
US4086346A (en) * 1974-04-06 1978-04-25 Bayer Aktiengesellschaft Preparation of melt-sprayed spherical phenacetin granules
DE3833446A1 (de) 1988-10-01 1990-04-05 Hoechst Ag Verfahren zur herstellung von arzneimittelwirkstoff-partikeln mit verbesserten fliess-, lager- und formulierungseigenschaften sowie arzneimittel, die diese arzneimittelwirkstoff-partikeln enthalten

Also Published As

Publication number Publication date
DE69309037T2 (de) 1997-07-24
EP0624087A1 (en) 1994-11-17
CN1079954A (zh) 1993-12-29
ZA93577B (en) 1994-01-13
CZ182894A3 (en) 1995-02-15
HU9402221D0 (en) 1994-09-28
EP0624087B1 (en) 1997-03-19
ES2099419T3 (es) 1997-05-16
AU3362693A (en) 1993-09-01
CA2129027A1 (en) 1993-08-05
FI943550A0 (fi) 1994-07-28
DK0624087T3 (da) 1997-09-01
MX9300430A (es) 1994-08-31
GB9201857D0 (en) 1992-03-18
BG98933A (en) 1995-07-28
NO942813L (no) 1994-07-28
NO942813D0 (no) 1994-07-28
GR3023142T3 (en) 1997-07-30
ATE150298T1 (de) 1997-04-15
WO1993014747A1 (en) 1993-08-05
KR950700056A (ko) 1995-01-16
IL104526A0 (en) 1993-05-13
HUT67462A (en) 1995-04-28
SK91694A3 (en) 1995-03-08
US5539000A (en) 1996-07-23
FI943550A (fi) 1994-07-28
DE69309037D1 (de) 1997-04-24
JPH07503245A (ja) 1995-04-06

Similar Documents

Publication Publication Date Title
BR9305674A (pt) Nabumetone endurecido por spray
FI20040608A (fi) Virtsasta peräisin oleva uusi proteiini, jota kutsutaan komponentti B:ksi
AR002932A1 (es) Solucion acuosa de interferon
FR2693112B1 (fr) Dispositif électromécanique d'injection à usage médical et vétérinaire actionné par une gâchette.
FR2713889B1 (fr) Composition pesticide contenant un régulateur de la croissance des insectes et un dérivé de N-aryldiazole.
FR2676173B1 (fr) Composition cosmetique contenant un agent alcalinisant sans odeur.
IT8121735A0 (it) Sorgente di polverizzazione intensificata magneticamente.
ES2137257T3 (es) Jeringa de una sola inyeccion.
SE9002468D0 (sv) A device and method for dosing a liquid product
MX9709398A (es) N-aril-1,2,4-triazolin-5-onas.
TW280760B (pt)
DK0874843T3 (da) Substituerede 4-(1H-benzimidazol-2-yl)(1,4)diazepaner, der er nyttige til behandling af allergisygdomme
FI934624A0 (fi) Enantiomera cis-3-(4,6-dihydroxikroman-3-ylmetyl)bensoesyror
ATE107165T1 (de) Verwendung von macrolactonen als antiallergica.
ES2145125T3 (es) Disposicion de proteccion de conmutador.
FI934977A0 (fi) Foerfarande foer att reducera elkfoerbrukningen i mikroprocessorbaserade,isynnerhet foer publika telefonstationer avsedda anordningar
ZA939199B (en) Methylbutoxy-propionitriles
TW366338B (en) Arylalkoxyphenoxy-imidazoline compounds
FR2694702B3 (fr) Bracelet therapeutique perfectionne.
FR2668993B1 (fr) Dispositif d'actionnement d'un maitre cylindre.
KR940010354U (ko) 클러치 부스터(clutch booster)
IT1269457B (it) Forno periodico
ITMO910013U1 (it) Emanatore di profumo di essenze, ricaricabile, per deodorare e profuma re ambienti.
SE9103040D0 (sv) Saekerhetsfodral
KR940018438U (ko) 피.오.피(p.o.p) 발생회로

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]