BR8603315A - Processo para produzir um implante de liberacao controlada;implante usado no processo;processo para purificar e concentrar hormonio de crescimento biologicamente ativo em uma forma adequada para incorporacao em um implante para administracao subcutanea - Google Patents

Processo para produzir um implante de liberacao controlada;implante usado no processo;processo para purificar e concentrar hormonio de crescimento biologicamente ativo em uma forma adequada para incorporacao em um implante para administracao subcutanea

Info

Publication number
BR8603315A
BR8603315A BR8603315A BR8603315A BR8603315A BR 8603315 A BR8603315 A BR 8603315A BR 8603315 A BR8603315 A BR 8603315A BR 8603315 A BR8603315 A BR 8603315A BR 8603315 A BR8603315 A BR 8603315A
Authority
BR
Brazil
Prior art keywords
implant
controlled release
growth hormone
subcutaneous administration
purify
Prior art date
Application number
BR8603315A
Other languages
English (en)
Inventor
Alvim M Janski
Ren-Der Yang
Original Assignee
Int Minerals & Chem Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Int Minerals & Chem Corp filed Critical Int Minerals & Chem Corp
Publication of BR8603315A publication Critical patent/BR8603315A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/27Growth hormone [GH], i.e. somatotropin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
BR8603315A 1985-07-15 1986-07-14 Processo para produzir um implante de liberacao controlada;implante usado no processo;processo para purificar e concentrar hormonio de crescimento biologicamente ativo em uma forma adequada para incorporacao em um implante para administracao subcutanea BR8603315A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/755,093 US4786501A (en) 1985-07-15 1985-07-15 Cylindrical implants for the controlled release of growth hormones

Publications (1)

Publication Number Publication Date
BR8603315A true BR8603315A (pt) 1987-02-24

Family

ID=25037706

Family Applications (1)

Application Number Title Priority Date Filing Date
BR8603315A BR8603315A (pt) 1985-07-15 1986-07-14 Processo para produzir um implante de liberacao controlada;implante usado no processo;processo para purificar e concentrar hormonio de crescimento biologicamente ativo em uma forma adequada para incorporacao em um implante para administracao subcutanea

Country Status (18)

Country Link
US (1) US4786501A (pt)
EP (1) EP0210039B1 (pt)
JP (2) JPH0822820B2 (pt)
KR (1) KR930008952B1 (pt)
CN (1) CN1026862C (pt)
AT (1) ATE84707T1 (pt)
AU (1) AU604639B2 (pt)
BR (1) BR8603315A (pt)
CA (1) CA1288196C (pt)
DE (1) DE3687551T2 (pt)
DK (1) DK173165B1 (pt)
ES (1) ES2002099A6 (pt)
IE (1) IE62302B1 (pt)
IL (1) IL79403A0 (pt)
MX (1) MX173196B (pt)
NZ (1) NZ216832A (pt)
PT (1) PT82978B (pt)
ZA (1) ZA865271B (pt)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5137874A (en) * 1985-07-29 1992-08-11 American Cyanamid Co. Partially coated C10 -C20 fatty acid salts of peptides having molecular weights up to about 5,000
US4761289A (en) * 1986-10-10 1988-08-02 International Minerals & Chemical Corp. Sustained release implant and method for preparing same
US4863736A (en) * 1987-03-16 1989-09-05 Monsanto Company Somatotropin prolonged release
US4837202A (en) * 1987-09-14 1989-06-06 Pitman-Moore, Inc. Method for stimulating the immune system
US5035891A (en) * 1987-10-05 1991-07-30 Syntex (U.S.A.) Inc. Controlled release subcutaneous implant
US5100668A (en) * 1988-06-14 1992-03-31 Massachusetts Institute Of Technology Controlled release systems containing heparin and growth factors
ATE130195T1 (de) * 1988-07-26 1995-12-15 Univ Rutgers Vorrichtungen und verfahren zur wachstumsförderung bei bratgeflügel.
US5179080A (en) * 1989-08-31 1993-01-12 Clinical Homecare, Corp. Formulations containing growth hormone and nutritional supplements, and methods of treating malnutrition in chronic lung disease
US5091185A (en) * 1990-06-20 1992-02-25 Monsanto Company Coated veterinary implants
US5232708A (en) * 1990-06-20 1993-08-03 Monsanto Company Coated veterinary implants
US5922342A (en) * 1990-10-01 1999-07-13 Pharmacia & Upjohn Company Lateral edge coated controlled release pharmaceutical compositions
IS3778A7 (is) * 1990-10-31 1992-05-02 Amgen Inc. Aðferð til að gefa dýrum vaxtarhormón, þar sem gefnu magni er stýrt
SE9303068D0 (sv) * 1993-09-21 1993-09-21 Kabi Pharmacia Ab New use
US5898030A (en) * 1994-06-17 1999-04-27 Applied Research Systems Ars Holding N.V hGH containing pharmaceutical compositions
US5672357A (en) * 1994-07-01 1997-09-30 Monsanto Company Method and device for implantation of large diameter objects in bovines
US5595752A (en) * 1994-07-01 1997-01-21 Monsanto Company Increasing dressing percentage and carcass weight in finishing beef cattle
IT1269221B (it) 1994-11-25 1997-03-21 Fondazione Clinica Del Lavoro Campionatore diffusivo a simmetria radiale di sostanze volatili, ad alta capacita' di pompaggio equivalente ed utile per il desorbimento chimico e termico.
AU744606B2 (en) * 1996-12-20 2002-02-28 Scientec Research Pty Ltd Apparatus and method for coating a material
AUPO431596A0 (en) * 1996-12-20 1997-01-23 Scientec Research Pty Ltd Apparatus and method for coating a material
KR19990071255A (ko) 1998-02-28 1999-09-15 성재갑 소마토트로핀과 비타민의 합제 조성물
AU766959B2 (en) * 1998-04-20 2003-10-30 Genzyme Corporation Drug delivery of proteins from polymeric blends
CA2451187C (en) * 2001-06-22 2012-08-14 Southern Biosystems, Inc. Zero-order prolonged release coaxial implants
AUPR602401A0 (en) * 2001-06-29 2001-07-26 Smart Drug Systems Inc Sustained release delivery system
US20060051347A1 (en) 2004-09-09 2006-03-09 Winter Charles M Process for concentration of antibodies and therapeutic products thereof
US8936805B2 (en) 2005-09-09 2015-01-20 Board Of Trustees Of The University Of Arkansas Bone regeneration using biodegradable polymeric nanocomposite materials and applications of the same
US9763788B2 (en) 2005-09-09 2017-09-19 Board Of Trustees Of The University Of Arkansas Bone regeneration using biodegradable polymeric nanocomposite materials and applications of the same
EP1931401A2 (en) * 2005-09-09 2008-06-18 University of Arkansas at Little Rock System and method for tissue generation and bone regeneration

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4450150A (en) * 1973-05-17 1984-05-22 Arthur D. Little, Inc. Biodegradable, implantable drug delivery depots, and method for preparing and using the same
US3993072A (en) * 1974-08-28 1976-11-23 Alza Corporation Microporous drug delivery device
US4158526A (en) * 1978-01-09 1979-06-19 General Electric Company Turbine assembly including a rotatable liquid collection ring
US4443539A (en) * 1980-02-05 1984-04-17 The Upjohn Company Process for preparing bovine growth hormone
IL59690A (en) * 1980-03-24 1983-11-30 Yeda Res & Dev Production of bovine growth hormone by microorganisms and modified microorganisms adapted to produce it
IE52755B1 (en) * 1980-08-26 1988-02-17 Univ California Bovine pre-growth and growth hormone
EP0085036A1 (en) * 1982-01-18 1983-08-03 Monsanto Company Method for improved bovine milk production
DE3214667C2 (de) * 1982-04-21 1985-07-18 Akzo Gmbh, 5600 Wuppertal Zusammengesetzter Körper für die Langzeitabgabe von Wirkstoffen
EP0103395A3 (en) * 1982-08-17 1985-05-22 Biogen N.V. Dna sequences, recombinant dna molecules and processes for producing bovine growth hormone-like polypeptides in high yield
CA1341012C (en) * 1982-09-27 2000-06-06 Biogen, Inc. Dna sequences, recombinant dna molecules and processes for producing swine growth hormone-like polypeptides
US4512922A (en) * 1982-12-22 1985-04-23 Genentech, Inc. Purification and activity assurance of precipitated heterologous proteins
US4511503A (en) * 1982-12-22 1985-04-16 Genentech, Inc. Purification and activity assurance of precipitated heterologous proteins
US4511502A (en) * 1982-12-22 1985-04-16 Genentech, Inc. Purification and activity assurance of precipitated heterologous proteins
US4576604A (en) * 1983-03-04 1986-03-18 Alza Corporation Osmotic system with instant drug availability
US4506680A (en) * 1983-03-17 1985-03-26 Medtronic, Inc. Drug dispensing body implantable lead
US4755465A (en) * 1983-04-25 1988-07-05 Genentech, Inc. Secretion of correctly processed human growth hormone in E. coli and Pseudomonas
US4563489A (en) * 1984-02-10 1986-01-07 University Of California Biodegradable organic polymer delivery system for bone morphogenetic protein
WO1985005377A1 (en) * 1984-05-11 1985-12-05 Codon Genetic Engineering Laboratories An efficient process for producing active chymosin from a precursor protein synthesized in bacteria
US4686098A (en) * 1984-05-14 1987-08-11 Merck & Co., Inc. Encapsulated mouse cells transformed with avian retrovirus-bovine growth hormone DNA, and a method of administering BGH in vivo
EP0193917A3 (en) * 1985-03-06 1987-09-23 American Cyanamid Company Water dispersible and water soluble carbohydrate polymer compositions for parenteral administration
US4670249A (en) * 1985-04-12 1987-06-02 International Minerals & Chemical Corp. Growth-promoting compositions
US4666704A (en) * 1985-05-24 1987-05-19 International Minerals & Chemical Corp. Controlled release delivery system for macromolecules

Also Published As

Publication number Publication date
AU604639B2 (en) 1991-01-03
AU6020186A (en) 1987-01-22
NZ216832A (en) 1989-01-06
ES2002099A6 (es) 1988-07-16
JPS6253928A (ja) 1987-03-09
DK336986A (da) 1987-01-16
CN86105858A (zh) 1987-06-03
ATE84707T1 (de) 1993-02-15
EP0210039A2 (en) 1987-01-28
EP0210039B1 (en) 1993-01-20
DK173165B1 (da) 2000-02-21
KR870000924A (ko) 1987-03-10
DK336986D0 (da) 1986-07-15
EP0210039A3 (en) 1988-07-06
IE861876L (en) 1987-01-15
MX173196B (es) 1994-02-07
US4786501A (en) 1988-11-22
PT82978A (en) 1986-08-01
CA1288196C (en) 1991-08-27
KR930008952B1 (ko) 1993-09-17
JPH0822820B2 (ja) 1996-03-06
PT82978B (pt) 1988-07-01
DE3687551D1 (de) 1993-03-04
JPH08205888A (ja) 1996-08-13
IL79403A0 (en) 1986-10-31
CN1026862C (zh) 1994-12-07
ZA865271B (en) 1987-03-25
DE3687551T2 (de) 1993-05-13
IE62302B1 (en) 1995-01-25

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Legal Events

Date Code Title Description
B15K Others concerning applications: alteration of classification

Ipc: A61K 9/00 (2006.01), A61K 38/27 (2006.0