DE3782420D1 - Wachstumhormonzubereitungen mit verzoegerter wirkstoffabgabe fuer eine parenterale verabreichung und ihre verwendung. - Google Patents
Wachstumhormonzubereitungen mit verzoegerter wirkstoffabgabe fuer eine parenterale verabreichung und ihre verwendung.Info
- Publication number
- DE3782420D1 DE3782420D1 DE8787119008T DE3782420T DE3782420D1 DE 3782420 D1 DE3782420 D1 DE 3782420D1 DE 8787119008 T DE8787119008 T DE 8787119008T DE 3782420 T DE3782420 T DE 3782420T DE 3782420 D1 DE3782420 D1 DE 3782420D1
- Authority
- DE
- Germany
- Prior art keywords
- parenteral administration
- active substances
- growth hormone
- delayed delivery
- hormone preparations
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000000122 growth hormone Substances 0.000 title abstract 3
- 206010012186 Delayed delivery Diseases 0.000 title 1
- 102000018997 Growth Hormone Human genes 0.000 title 1
- 108010051696 Growth Hormone Proteins 0.000 title 1
- 239000013543 active substance Substances 0.000 title 1
- 238000007911 parenteral administration Methods 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 241001465754 Metazoa Species 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 208000021017 Weight Gain Diseases 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008267 milk Substances 0.000 abstract 1
- 210000004080 milk Anatomy 0.000 abstract 1
- 235000013336 milk Nutrition 0.000 abstract 1
- 238000013268 sustained release Methods 0.000 abstract 1
- 239000012730 sustained-release form Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
- 230000004584 weight gain Effects 0.000 abstract 1
- 235000019786 weight gain Nutrition 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH], i.e. somatotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/113—Multiple emulsions, e.g. oil-in-water-in-oil
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Endocrinology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Zoology (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
- Closures For Containers (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/002,536 US4857506A (en) | 1987-01-12 | 1987-01-12 | Sustained release growth hormone compositions for parenteral administration and their use |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3782420D1 true DE3782420D1 (de) | 1992-12-03 |
DE3782420T2 DE3782420T2 (de) | 1993-03-11 |
Family
ID=21701224
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8787119008T Expired - Fee Related DE3782420T2 (de) | 1987-01-12 | 1987-12-22 | Wachstumhormonzubereitungen mit verzoegerter wirkstoffabgabe fuer eine parenterale verabreichung und ihre verwendung. |
Country Status (15)
Country | Link |
---|---|
US (1) | US4857506A (de) |
EP (1) | EP0278103B1 (de) |
JP (1) | JPS63258425A (de) |
AT (1) | ATE81781T1 (de) |
AU (1) | AU597462B2 (de) |
CA (1) | CA1318587C (de) |
DE (1) | DE3782420T2 (de) |
DK (1) | DK10088A (de) |
ES (1) | ES2052542T3 (de) |
FI (1) | FI880101A (de) |
GR (1) | GR3006124T3 (de) |
HU (1) | HU197992B (de) |
IL (1) | IL84907A0 (de) |
NZ (1) | NZ223010A (de) |
ZA (1) | ZA88152B (de) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5981485A (en) * | 1997-07-14 | 1999-11-09 | Genentech, Inc. | Human growth hormone aqueous formulation |
US5763394A (en) * | 1988-04-15 | 1998-06-09 | Genentech, Inc. | Human growth hormone aqueous formulation |
WO1990008537A1 (en) * | 1989-02-06 | 1990-08-09 | Abbott Laboratories | Pharmaceutical compositions for oral administration |
US5232704A (en) * | 1990-12-19 | 1993-08-03 | G. D. Searle & Co. | Sustained release, bilayer buoyant dosage form |
YU87892A (sh) * | 1991-10-01 | 1995-12-04 | Eli Lilly And Company Lilly Corporate Center | Injektibilne formulacije produženog otpuštanja i postupci za njihovo dobijanje i primenu |
IL103275A0 (en) * | 1991-10-01 | 1993-02-21 | Lilly Co Eli | Injectable extended release formulations and methods |
WO1993010758A1 (en) * | 1991-12-05 | 1993-06-10 | Pitman-Moore, Inc. | A carbohydrate glass matrix for the sustained release of a therapeutic agent |
US5342612A (en) * | 1991-12-20 | 1994-08-30 | American Cyanamid Company | Compositions for the treatment of mammalian diseases |
DE4206732A1 (de) * | 1992-03-04 | 1993-09-09 | Goldschmidt Ag Th | Fluessige, lagerstabile, multiple emulsion des typs o/w/o |
US5426096A (en) * | 1992-03-18 | 1995-06-20 | Soenksen; Peter | Use of human growth hormone |
US5643867A (en) * | 1992-08-26 | 1997-07-01 | Celtrix Pharmaceuticals, Inc. | Method for treating catabolic conditions |
DE4322174A1 (de) * | 1993-07-03 | 1995-01-12 | Goldschmidt Ag Th | Flüssige oder pastöse, lagerstabile, multiple Emulsion des Typs W·1·/O/W·2· |
SE9303068D0 (sv) * | 1993-09-21 | 1993-09-21 | Kabi Pharmacia Ab | New use |
ZA949350B (en) | 1994-01-25 | 1996-05-24 | Upjohn Co | Aqueous prolonged release formulation |
GB9410092D0 (en) * | 1994-05-19 | 1994-07-06 | Kelco Int Ltd | Emulsion, method and use |
US5589177A (en) * | 1994-12-06 | 1996-12-31 | Helene Curtis, Inc. | Rinse-off water-in-oil-in-water compositions |
US6528483B2 (en) | 1995-06-07 | 2003-03-04 | André Beaulieu | Method of producing concentrated non-buffered solutions of fibronectin |
US5821220A (en) * | 1995-06-07 | 1998-10-13 | Andre Beaulieu | Method of producing concentrated non-buffered solutions of fibronectin |
FR2742354B1 (fr) * | 1995-12-15 | 1998-01-23 | Oreal | Emulsion e/h/e stable contenant un actif cosmetique et/ou dermatologique sensible a l'eau |
GB9626865D0 (en) * | 1996-12-24 | 1997-02-12 | Cyanamid Websters Pty Limited | Veterinary vaccines |
ZA9711731B (en) * | 1996-12-31 | 1998-07-01 | Monsanto Co | Aqueous glycerol formulations of somatotropin |
KR19990071255A (ko) | 1998-02-28 | 1999-09-15 | 성재갑 | 소마토트로핀과 비타민의 합제 조성물 |
GB9827600D0 (en) | 1998-12-15 | 1999-02-10 | De Beers Ind Diamond | Abrasive product |
KR20090007504A (ko) | 2000-02-24 | 2009-01-16 | 몬산토 테크놀로지 엘엘씨 | 소마토트로핀의 지속적인 방출을 위한 비수성 주사제제들 |
KR20030023878A (ko) | 2000-06-26 | 2003-03-20 | 몬산토 테크놀로지 엘엘씨 | 소마토트로핀의 지속적인 방출을 위한 계면활성제 함유비수성 제제들 |
US6664234B1 (en) | 2000-06-30 | 2003-12-16 | Monsanto Technology Llc | Non-aqueous injectable formulation preparation with pH adjusted for extended release of somatotropin |
DK1320356T4 (da) * | 2000-09-20 | 2011-09-12 | Nycomed Pharma As | Fremstilling af vitaminemulsioner og koncentrater deraf |
FR2852247A1 (fr) * | 2003-03-11 | 2004-09-17 | Centre Nat Rech Scient | Utilisation de ligands peptidiques de recepteurs de la membrane plasmique et de leurs analogues pour moduler l'activite des mitochondries |
TWI380815B (zh) * | 2009-12-02 | 2013-01-01 | Univ Nat Pingtung Sci & Tech | 一種應用於甲殼綱生物性腺發展之緩釋藥劑 |
TWI400064B (zh) * | 2009-12-08 | 2013-07-01 | Univ Nat Pingtung Sci & Tech | 一種蝦類生物的注射方法 |
AU2010341518B2 (en) | 2009-12-21 | 2014-01-09 | Ambrx, Inc. | Modified porcine somatotropin polypeptides and their uses |
JP2013515080A (ja) | 2009-12-21 | 2013-05-02 | アンブルックス,インコーポレイテッド | 修飾されているウシのソマトトロピンポリペプチドおよびそれらの使用 |
WO2017199008A1 (en) * | 2016-05-16 | 2017-11-23 | The University Of Birmingham | Emulsion |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4521409A (en) * | 1983-10-03 | 1985-06-04 | Cornell Research Foundation, Inc. | Use of growth hormone to enhance ruminant mammary development |
DE3484584D1 (de) * | 1983-10-14 | 1991-06-20 | Sumitomo Pharma | Injektionen mit verzoegerter abgabe. |
KR890002631B1 (ko) * | 1984-10-04 | 1989-07-21 | 몬산토 캄파니 | 생물학적으로 활성인 소마토트로핀을 지속적으로 유리하는 조성물 |
EP0193917A3 (de) * | 1985-03-06 | 1987-09-23 | American Cyanamid Company | Wasserdispersible und wasserlösliche Polymerzusammensetzungen für parenterale Anwendung |
IL79765A (en) * | 1985-08-23 | 1992-02-16 | Lilly Co Eli | Injectable sustained release formulations of bovine somatotropin |
-
1987
- 1987-01-12 US US07/002,536 patent/US4857506A/en not_active Expired - Lifetime
- 1987-12-21 NZ NZ223010A patent/NZ223010A/en unknown
- 1987-12-22 DE DE8787119008T patent/DE3782420T2/de not_active Expired - Fee Related
- 1987-12-22 EP EP87119008A patent/EP0278103B1/de not_active Expired - Lifetime
- 1987-12-22 ES ES87119008T patent/ES2052542T3/es not_active Expired - Lifetime
- 1987-12-22 IL IL84907A patent/IL84907A0/xx unknown
- 1987-12-22 AT AT87119008T patent/ATE81781T1/de active
-
1988
- 1988-01-08 CA CA000556088A patent/CA1318587C/en not_active Expired - Fee Related
- 1988-01-11 JP JP63002658A patent/JPS63258425A/ja active Pending
- 1988-01-11 ZA ZA880152A patent/ZA88152B/xx unknown
- 1988-01-11 AU AU10170/88A patent/AU597462B2/en not_active Ceased
- 1988-01-11 HU HU8882A patent/HU197992B/hu unknown
- 1988-01-11 FI FI880101A patent/FI880101A/fi not_active Application Discontinuation
- 1988-01-11 DK DK010088A patent/DK10088A/da not_active Application Discontinuation
-
1992
- 1992-11-02 GR GR920400980T patent/GR3006124T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
NZ223010A (en) | 1990-11-27 |
DE3782420T2 (de) | 1993-03-11 |
EP0278103B1 (de) | 1992-10-28 |
AU1017088A (en) | 1988-07-14 |
AU597462B2 (en) | 1990-05-31 |
HUT46233A (en) | 1988-10-28 |
IL84907A0 (en) | 1988-06-30 |
CA1318587C (en) | 1993-06-01 |
DK10088A (da) | 1988-07-13 |
GR3006124T3 (de) | 1993-06-21 |
EP0278103A3 (en) | 1990-04-04 |
ZA88152B (en) | 1988-06-28 |
ES2052542T3 (es) | 1994-07-16 |
EP0278103A2 (de) | 1988-08-17 |
FI880101A (fi) | 1988-07-13 |
US4857506A (en) | 1989-08-15 |
JPS63258425A (ja) | 1988-10-25 |
DK10088D0 (da) | 1988-01-11 |
FI880101A0 (fi) | 1988-01-11 |
ATE81781T1 (de) | 1992-11-15 |
HU197992B (en) | 1989-07-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |