EP0278103A3 - Sustained release growth hormone compositions for parenteral administration and their use - Google Patents

Sustained release growth hormone compositions for parenteral administration and their use Download PDF

Info

Publication number
EP0278103A3
EP0278103A3 EP87119008A EP87119008A EP0278103A3 EP 0278103 A3 EP0278103 A3 EP 0278103A3 EP 87119008 A EP87119008 A EP 87119008A EP 87119008 A EP87119008 A EP 87119008A EP 0278103 A3 EP0278103 A3 EP 0278103A3
Authority
EP
European Patent Office
Prior art keywords
sustained release
parenteral administration
growth hormone
release growth
increasing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP87119008A
Other versions
EP0278103A2 (en
EP0278103B1 (en
Inventor
Praveen Tyle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Priority to AT87119008T priority Critical patent/ATE81781T1/en
Publication of EP0278103A2 publication Critical patent/EP0278103A2/en
Publication of EP0278103A3 publication Critical patent/EP0278103A3/en
Application granted granted Critical
Publication of EP0278103B1 publication Critical patent/EP0278103B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/113—Multiple emulsions, e.g. oil-in-water-in-oil

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Closures For Containers (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

The invention relates to sustained release compositions of growth hormones and/or related compounds and multiple water-in oil-in water emulsions. The invention also relates to methods for increasing and maintaining increased levels of growth hormones and/or related compounds in the blood of treated animals for extended periods of time, increasing weight gains in animals and increasing milk production of lactating animals by the administration of a composition of the invention.
EP87119008A 1987-01-12 1987-12-22 Sustained release growth hormone compositions for parenteral administration and their use Expired - Lifetime EP0278103B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT87119008T ATE81781T1 (en) 1987-01-12 1987-12-22 DELAYED-RELEASE GROWTH HORMONE PREPARATIONS FOR PARENTERAL ADMINISTRATION AND THEIR USE.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/002,536 US4857506A (en) 1987-01-12 1987-01-12 Sustained release growth hormone compositions for parenteral administration and their use
US2536 1987-01-12

Publications (3)

Publication Number Publication Date
EP0278103A2 EP0278103A2 (en) 1988-08-17
EP0278103A3 true EP0278103A3 (en) 1990-04-04
EP0278103B1 EP0278103B1 (en) 1992-10-28

Family

ID=21701224

Family Applications (1)

Application Number Title Priority Date Filing Date
EP87119008A Expired - Lifetime EP0278103B1 (en) 1987-01-12 1987-12-22 Sustained release growth hormone compositions for parenteral administration and their use

Country Status (15)

Country Link
US (1) US4857506A (en)
EP (1) EP0278103B1 (en)
JP (1) JPS63258425A (en)
AT (1) ATE81781T1 (en)
AU (1) AU597462B2 (en)
CA (1) CA1318587C (en)
DE (1) DE3782420T2 (en)
DK (1) DK10088A (en)
ES (1) ES2052542T3 (en)
FI (1) FI880101A (en)
GR (1) GR3006124T3 (en)
HU (1) HU197992B (en)
IL (1) IL84907A0 (en)
NZ (1) NZ223010A (en)
ZA (1) ZA88152B (en)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5981485A (en) * 1997-07-14 1999-11-09 Genentech, Inc. Human growth hormone aqueous formulation
US5763394A (en) * 1988-04-15 1998-06-09 Genentech, Inc. Human growth hormone aqueous formulation
AU5157590A (en) * 1989-02-06 1990-08-24 Abbott Laboratories Pharmaceutical compositions for oral administration
US5232704A (en) * 1990-12-19 1993-08-03 G. D. Searle & Co. Sustained release, bilayer buoyant dosage form
IL103275A0 (en) * 1991-10-01 1993-02-21 Lilly Co Eli Injectable extended release formulations and methods
YU87892A (en) * 1991-10-01 1995-12-04 Eli Lilly And Company Lilly Corporate Center INJECTIBLE LONG TERM RELEASE FORMULATIONS AND PROCEDURES FOR THEIR OBTAINING AND USE
ATE140620T1 (en) * 1991-12-05 1996-08-15 Mallinckrodt Veterinary Inc GLASSY CARBOHYDRATE MATRICE FOR ADMINISTRATION OF DELAYED RELEASE MEDICATIONS
US5342612A (en) * 1991-12-20 1994-08-30 American Cyanamid Company Compositions for the treatment of mammalian diseases
DE4206732A1 (en) * 1992-03-04 1993-09-09 Goldschmidt Ag Th LIQUID, STORAGE STABLE, MULTIPLE EMULSION OF THE TYPE O / W / O
US5426096A (en) * 1992-03-18 1995-06-20 Soenksen; Peter Use of human growth hormone
US5643867A (en) * 1992-08-26 1997-07-01 Celtrix Pharmaceuticals, Inc. Method for treating catabolic conditions
DE4322174A1 (en) * 1993-07-03 1995-01-12 Goldschmidt Ag Th Liquid or pasty, storage-stable, multiple emulsion of the type W · 1 · / O / W · 2 ·
SE9303068D0 (en) * 1993-09-21 1993-09-21 Kabi Pharmacia Ab New use
ZA949350B (en) 1994-01-25 1996-05-24 Upjohn Co Aqueous prolonged release formulation
GB9410092D0 (en) * 1994-05-19 1994-07-06 Kelco Int Ltd Emulsion, method and use
US5589177A (en) * 1994-12-06 1996-12-31 Helene Curtis, Inc. Rinse-off water-in-oil-in-water compositions
US5821220A (en) * 1995-06-07 1998-10-13 Andre Beaulieu Method of producing concentrated non-buffered solutions of fibronectin
US6528483B2 (en) 1995-06-07 2003-03-04 André Beaulieu Method of producing concentrated non-buffered solutions of fibronectin
FR2742354B1 (en) * 1995-12-15 1998-01-23 Oreal STABLE W / O / W EMULSION CONTAINING A WATER SENSITIVE COSMETIC AND / OR DERMATOLOGICAL ACTIVE AGENT
GB9626865D0 (en) * 1996-12-24 1997-02-12 Cyanamid Websters Pty Limited Veterinary vaccines
ZA9711731B (en) * 1996-12-31 1998-07-01 Monsanto Co Aqueous glycerol formulations of somatotropin
KR19990071255A (en) 1998-02-28 1999-09-15 성재갑 Combination composition of somatotropin and vitamin
GB9827600D0 (en) 1998-12-15 1999-02-10 De Beers Ind Diamond Abrasive product
KR20090007504A (en) 2000-02-24 2009-01-16 몬산토 테크놀로지 엘엘씨 Non-aqueous injectable formulations for extended release of somatotropin
WO2002000261A2 (en) 2000-06-26 2002-01-03 Monsanto Technology Llc Surfactant-containing formulations for extended release of somatotropin
US6664234B1 (en) * 2000-06-30 2003-12-16 Monsanto Technology Llc Non-aqueous injectable formulation preparation with pH adjusted for extended release of somatotropin
DE60131862D1 (en) * 2000-09-20 2008-01-24 Nycomed Pharma As PREPARATION OF VITAMIN EMULSIONS AND CONCENTRATES THEREOF
FR2852247A1 (en) * 2003-03-11 2004-09-17 Centre Nat Rech Scient Using a peptide ligand of a plasma membrane receptor for modulating mitochondrial activity, useful for treatment or prevention of e.g. cancer or obesity
TWI380815B (en) * 2009-12-02 2013-01-01 Univ Nat Pingtung Sci & Tech A time-released medication for applying to crustacean ovarian development
TWI400064B (en) * 2009-12-08 2013-07-01 Univ Nat Pingtung Sci & Tech An injection method for shrimps
CN102753573A (en) 2009-12-21 2012-10-24 Ambrx公司 Modified bovine somatotropin polypeptides and their uses
NZ600363A (en) 2009-12-21 2014-07-25 Ambrx Inc Modified porcine somatotropin polypeptides and their uses
WO2017199008A1 (en) * 2016-05-16 2017-11-23 The University Of Birmingham Emulsion

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0140255A2 (en) * 1983-10-14 1985-05-08 Sumitomo Pharmaceuticals Company, Limited Sustained-release injections
EP0177478A2 (en) * 1984-10-04 1986-04-09 Monsanto Company Prolonged release of biologically active somatotropins
EP0193917A2 (en) * 1985-03-06 1986-09-10 American Cyanamid Company Water dispersible and water soluble carbohydrate polymer compositions for parenteral administration

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4521409A (en) * 1983-10-03 1985-06-04 Cornell Research Foundation, Inc. Use of growth hormone to enhance ruminant mammary development
CA1285874C (en) * 1985-08-23 1991-07-09 Thomas Harry Ferguson Injectable sustained release formulation

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0140255A2 (en) * 1983-10-14 1985-05-08 Sumitomo Pharmaceuticals Company, Limited Sustained-release injections
EP0177478A2 (en) * 1984-10-04 1986-04-09 Monsanto Company Prolonged release of biologically active somatotropins
EP0193917A2 (en) * 1985-03-06 1986-09-10 American Cyanamid Company Water dispersible and water soluble carbohydrate polymer compositions for parenteral administration

Also Published As

Publication number Publication date
IL84907A0 (en) 1988-06-30
NZ223010A (en) 1990-11-27
FI880101A (en) 1988-07-13
DE3782420D1 (en) 1992-12-03
DE3782420T2 (en) 1993-03-11
DK10088A (en) 1988-07-13
HUT46233A (en) 1988-10-28
ATE81781T1 (en) 1992-11-15
DK10088D0 (en) 1988-01-11
EP0278103A2 (en) 1988-08-17
ES2052542T3 (en) 1994-07-16
JPS63258425A (en) 1988-10-25
HU197992B (en) 1989-07-28
ZA88152B (en) 1988-06-28
AU597462B2 (en) 1990-05-31
AU1017088A (en) 1988-07-14
FI880101A0 (en) 1988-01-11
EP0278103B1 (en) 1992-10-28
CA1318587C (en) 1993-06-01
US4857506A (en) 1989-08-15
GR3006124T3 (en) 1993-06-21

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