BR112022024743A2 - - Google Patents

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Publication number
BR112022024743A2
BR112022024743A2 BR112022024743A BR112022024743A BR112022024743A2 BR 112022024743 A2 BR112022024743 A2 BR 112022024743A2 BR 112022024743 A BR112022024743 A BR 112022024743A BR 112022024743 A BR112022024743 A BR 112022024743A BR 112022024743 A2 BR112022024743 A2 BR 112022024743A2
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BR
Brazil
Application number
BR112022024743A
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Portuguese (pt)
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BR112022024743B1 (pt
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Publication of BR112022024743A2 publication Critical patent/BR112022024743A2/pt
Publication of BR112022024743B1 publication Critical patent/BR112022024743B1/pt

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0603Embryonic cells ; Embryoid bodies
    • C12N5/0605Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • G01N33/533Production of labelled immunochemicals with fluorescent label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081Purging biological preparations of unwanted cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2509/00Methods for the dissociation of cells, e.g. specific use of enzymes
    • C12N2509/10Mechanical dissociation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/149Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N2015/1006Investigating individual particles for cytology
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Reproductive Health (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Dispersion Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Endocrinology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
BR112022024743-5A 2021-05-20 2022-03-16 Método para isolar células trofoblásticas placentárias a partir de células esfoliadas cervicais de mulheres grávidas BR112022024743B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN202110549947.8 2021-05-20
CN202110549947.8A CN112980779B (zh) 2021-05-20 2021-05-20 一种从孕妇宫颈脱落细胞中分离胎盘滋养层细胞的方法
PCT/CN2022/081234 WO2022242285A1 (zh) 2021-05-20 2022-03-16 一种从孕妇宫颈脱落细胞中分离胎盘滋养层细胞的方法

Publications (2)

Publication Number Publication Date
BR112022024743A2 true BR112022024743A2 (US20040232935A1-20041125-M00001.png) 2023-06-27
BR112022024743B1 BR112022024743B1 (pt) 2024-03-05

Family

ID=76337075

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022024743-5A BR112022024743B1 (pt) 2021-05-20 2022-03-16 Método para isolar células trofoblásticas placentárias a partir de células esfoliadas cervicais de mulheres grávidas

Country Status (8)

Country Link
US (1) US11796443B2 (US20040232935A1-20041125-M00001.png)
EP (1) EP4144834B1 (US20040232935A1-20041125-M00001.png)
JP (1) JP7368642B2 (US20040232935A1-20041125-M00001.png)
KR (1) KR102626620B1 (US20040232935A1-20041125-M00001.png)
CN (1) CN112980779B (US20040232935A1-20041125-M00001.png)
AU (1) AU2022277079B2 (US20040232935A1-20041125-M00001.png)
BR (1) BR112022024743B1 (US20040232935A1-20041125-M00001.png)
WO (1) WO2022242285A1 (US20040232935A1-20041125-M00001.png)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112980779B (zh) 2021-05-20 2021-08-24 广州凯普医药科技有限公司 一种从孕妇宫颈脱落细胞中分离胎盘滋养层细胞的方法

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WO1994002646A1 (en) * 1992-07-17 1994-02-03 Aprogenex Inc. Enriching and identyfying fetal cells in maternal blood for in situ hybridization
US5714325A (en) * 1993-09-24 1998-02-03 New England Medical Center Hospitals Prenatal diagnosis by isolation of fetal granulocytes from maternal blood
CA2213620A1 (en) * 1995-04-07 1996-10-10 The Regents Of The University Of California Antibodies for the detection of hla-g
US20020045196A1 (en) * 2000-05-12 2002-04-18 Walt Mahoney Methods of isolating trophoblast cells from maternal blood
AUPR749901A0 (en) * 2001-09-06 2001-09-27 Monash University Method of identifying chromosomal abnormalities and prenatal diagnosis
US20050181429A1 (en) * 2003-04-03 2005-08-18 Monaliza Medical Ltd. Non-invasive prenatal genetic diagnosis using transcervical cells
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WO2005047532A1 (en) * 2003-11-17 2005-05-26 Gribbles Molecular Science Pty Ltd Improved method of performing genetic analyses on reproductive tract cell samples
US20070224597A1 (en) * 2006-03-23 2007-09-27 Biocept, Inc. Isolating fetal trophoblasts
DE102007019017A1 (de) * 2007-04-19 2009-01-22 Ldt Laser Display Technology Gmbh Verfahren und Vorrichtung zum Projizieren eines Bildes auf eine Projektionsfläche
ITTO20070307A1 (it) * 2007-05-04 2008-11-05 Silicon Biosystems Spa Metodo e dispositivo per la diagnosi prenatale non-invasiva
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CN101726585A (zh) * 2009-11-30 2010-06-09 宁波普赛微流科技有限公司 一种基于微流控芯片的流式细胞仪
WO2013174948A1 (en) * 2012-05-24 2013-11-28 Rarecells Process for multi-analyses of rare cells extracted or isolated from biological samples through filtration
ES2729182T3 (es) * 2012-10-19 2019-10-30 Univ Wayne State Identificación y análisis de células de trofoblastos fetales en mucus cervical para diagnosis prenatal
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CN107312747A (zh) * 2016-12-20 2017-11-03 华东医药(杭州)基因科技有限公司 一种免疫磁珠法分离胎盘滋养层细胞的方法
CN108265051B (zh) * 2016-12-30 2020-08-25 张婧 用于从母体捕获和分离胎儿细胞的无创方法和试剂盒
WO2019153032A1 (en) * 2018-02-07 2019-08-15 University Of South Australia Pre-natal cell isolation
CN108535228B (zh) * 2018-04-03 2020-12-25 德运康明(厦门)生物科技有限公司 一种从孕妇外周血中分离游离胎儿细胞的方法
TWI668423B (zh) * 2018-10-02 2019-08-11 吳宏偉 細胞分選方法及系統
CN110117571B (zh) * 2019-05-08 2023-01-31 南方医科大学南方医院 无创获取胎儿稀有细胞的试剂盒及其方法
JP2022536121A (ja) * 2019-06-07 2022-08-12 アルセディ バイオテック エーピーエス Facsを用いた胎児細胞の単離
JP7559043B2 (ja) * 2019-07-15 2024-10-01 エー. メナリニ バイオマーカーズ シンガポール プライベート リミテッド 胎児細胞を単離、検出及び解析する組成物及び方法
CN111304153A (zh) * 2019-12-17 2020-06-19 广东凯普生物科技股份有限公司 一种分离滋养层细胞的方法
CN111440696B (zh) * 2020-02-26 2023-02-24 德运康明(厦门)生物科技有限公司 胎儿细胞捕获模块、用于胎儿细胞捕获的微流控芯片,及它们的使用方法
CN112980779B (zh) * 2021-05-20 2021-08-24 广州凯普医药科技有限公司 一种从孕妇宫颈脱落细胞中分离胎盘滋养层细胞的方法

Also Published As

Publication number Publication date
AU2022277079B2 (en) 2024-07-04
EP4144834A1 (en) 2023-03-08
EP4144834A4 (en) 2023-09-27
US11796443B2 (en) 2023-10-24
KR102626620B1 (ko) 2024-01-17
BR112022024743B1 (pt) 2024-03-05
CN112980779A (zh) 2021-06-18
AU2022277079A1 (en) 2023-01-19
JP2023527246A (ja) 2023-06-27
WO2022242285A1 (zh) 2022-11-24
EP4144834B1 (en) 2024-10-23
JP7368642B2 (ja) 2023-10-24
US20230228667A1 (en) 2023-07-20
KR20230004915A (ko) 2023-01-06
CN112980779B (zh) 2021-08-24

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 16/03/2022, OBSERVADAS AS CONDICOES LEGAIS