BR112022022585A2 - Métodos para a identificação de uma condição médica em um indivíduo humano - Google Patents
Métodos para a identificação de uma condição médica em um indivíduo humanoInfo
- Publication number
- BR112022022585A2 BR112022022585A2 BR112022022585A BR112022022585A BR112022022585A2 BR 112022022585 A2 BR112022022585 A2 BR 112022022585A2 BR 112022022585 A BR112022022585 A BR 112022022585A BR 112022022585 A BR112022022585 A BR 112022022585A BR 112022022585 A2 BR112022022585 A2 BR 112022022585A2
- Authority
- BR
- Brazil
- Prior art keywords
- stem cells
- medical condition
- sample
- oct4a
- small embryonic
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Pathology (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medical Treatment And Welfare Office Work (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
MÉTODOS PARA A IDENTIFICAÇÃO DE UMA CONDIÇÃO MÉDICA EM UM INDIVÍDUO HUMANO. A presente divulgação divulga um método in vitro e não invasivo para a detecção de uma condição médica em um indivíduo. O método envolve o enriquecimento de células-tronco do tipo embrionárias muito pequenas a partir da amostra, para a obtenção de uma mistura compreendendo as referidas células-tronco do tipo embrionárias muito pequenas; a obtenção de ácido nucleico a partir da mistura da etapa; a realização de um ensaio com o ácido nucleico para a análise do nível de expressão de Oct4A nas células-tronco do tipo embrionárias muito pequenas a partir da amostra; e a comparação do nível de expressão de Oct4A nas células-tronco do tipo embrionárias muito pequenas a partir da amostra com um nível de expressão de Oct4A em uma amostra controle. A presente divulgação também fornece um método para a previsão do início de câncer e para a previsão da presença de câncer. Um método para o tratamento de câncer é também aqui divulgado. Além disso, um kit de reagente e um kit de detecção são também divulgados.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SG10202004280V | 2020-05-08 | ||
| PCT/SG2021/050254 WO2021225527A1 (en) | 2020-05-08 | 2021-05-07 | Methods for identifying a medical condition in a human subject |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112022022585A2 true BR112022022585A2 (pt) | 2022-12-13 |
Family
ID=76035107
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112022022585A BR112022022585A2 (pt) | 2020-05-08 | 2021-05-07 | Métodos para a identificação de uma condição médica em um indivíduo humano |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20230212688A1 (pt) |
| EP (1) | EP4146830A1 (pt) |
| JP (1) | JP2023529064A (pt) |
| KR (1) | KR20230008756A (pt) |
| CN (1) | CN116075598A (pt) |
| AU (1) | AU2021267468A1 (pt) |
| BR (1) | BR112022022585A2 (pt) |
| CA (1) | CA3177987A1 (pt) |
| IL (1) | IL297967A (pt) |
| MX (1) | MX2022013833A (pt) |
| WO (1) | WO2021225527A1 (pt) |
| ZA (1) | ZA202211940B (pt) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022224277A1 (en) * | 2021-04-21 | 2022-10-27 | 23Ikigai Pte Ltd. | Method for detecting medical conditions using analysis of very small embryonic-like stem cells |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6899771B2 (ja) * | 2014-08-12 | 2021-07-14 | ギリース・マッキンドー・リサーチ・インスティチュートＧｉｌｌｉｅｓ Ｍｃｉｎｄｏｅ Ｒｅｓｅａｒｃｈ Ｉｎｓｔｉｔｕｔｅ | 癌の診断及び治療 |
-
2021
- 2021-05-07 MX MX2022013833A patent/MX2022013833A/es unknown
- 2021-05-07 IL IL297967A patent/IL297967A/en unknown
- 2021-05-07 EP EP21727010.7A patent/EP4146830A1/en active Pending
- 2021-05-07 KR KR1020227041089A patent/KR20230008756A/ko active Search and Examination
- 2021-05-07 BR BR112022022585A patent/BR112022022585A2/pt unknown
- 2021-05-07 JP JP2022567889A patent/JP2023529064A/ja active Pending
- 2021-05-07 US US17/998,252 patent/US20230212688A1/en active Pending
- 2021-05-07 CN CN202180033608.2A patent/CN116075598A/zh active Pending
- 2021-05-07 WO PCT/SG2021/050254 patent/WO2021225527A1/en active Application Filing
- 2021-05-07 AU AU2021267468A patent/AU2021267468A1/en active Pending
- 2021-05-07 CA CA3177987A patent/CA3177987A1/en active Pending
-
2022
- 2022-11-02 ZA ZA2022/11940A patent/ZA202211940B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20230008756A (ko) | 2023-01-16 |
| US20230212688A1 (en) | 2023-07-06 |
| ZA202211940B (en) | 2023-02-22 |
| WO2021225527A1 (en) | 2021-11-11 |
| EP4146830A1 (en) | 2023-03-15 |
| IL297967A (en) | 2023-01-01 |
| JP2023529064A (ja) | 2023-07-07 |
| CA3177987A1 (en) | 2021-11-11 |
| AU2021267468A1 (en) | 2023-02-02 |
| MX2022013833A (es) | 2022-12-06 |
| CN116075598A (zh) | 2023-05-05 |
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