BR112022012075A2 - Métodos para tratar nefropatia por iga com atrasentan - Google Patents

Métodos para tratar nefropatia por iga com atrasentan

Info

Publication number
BR112022012075A2
BR112022012075A2 BR112022012075A BR112022012075A BR112022012075A2 BR 112022012075 A2 BR112022012075 A2 BR 112022012075A2 BR 112022012075 A BR112022012075 A BR 112022012075A BR 112022012075 A BR112022012075 A BR 112022012075A BR 112022012075 A2 BR112022012075 A2 BR 112022012075A2
Authority
BR
Brazil
Prior art keywords
atrasentan
decreasing
methods
iga nephropathy
subject
Prior art date
Application number
BR112022012075A
Other languages
English (en)
Portuguese (pt)
Inventor
Thomas Frohlich Philip
James King Andrew
Ramachandran Chidambaram
Beth Noonberg Sarah
Original Assignee
Chinook Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinook Therapeutics Inc filed Critical Chinook Therapeutics Inc
Publication of BR112022012075A2 publication Critical patent/BR112022012075A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/472Non-condensed isoquinolines, e.g. papaverine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12Antidiuretics, e.g. drugs for diabetes insipidus
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
BR112022012075A 2019-12-17 2020-12-16 Métodos para tratar nefropatia por iga com atrasentan BR112022012075A2 (pt)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201962949115P 2019-12-17 2019-12-17
US202063005003P 2020-04-03 2020-04-03
US202063072699P 2020-08-31 2020-08-31
US202063084739P 2020-09-29 2020-09-29
US202063125205P 2020-12-14 2020-12-14
PCT/US2020/065311 WO2021126977A1 (en) 2019-12-17 2020-12-16 Methods of treating iga nephropathy with atrasentan

Publications (1)

Publication Number Publication Date
BR112022012075A2 true BR112022012075A2 (pt) 2022-08-30

Family

ID=76478538

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022012075A BR112022012075A2 (pt) 2019-12-17 2020-12-16 Métodos para tratar nefropatia por iga com atrasentan

Country Status (13)

Country Link
US (11) US20210353593A1 (enExample)
EP (1) EP4076652B1 (enExample)
JP (2) JP7624995B2 (enExample)
KR (1) KR20230015874A (enExample)
CN (3) CN116327758A (enExample)
AU (1) AU2020404984A1 (enExample)
BR (1) BR112022012075A2 (enExample)
CA (1) CA3161516A1 (enExample)
IL (1) IL293921A (enExample)
MX (1) MX2022007471A (enExample)
PH (1) PH12022551456A1 (enExample)
TW (1) TWI875895B (enExample)
WO (1) WO2021126977A1 (enExample)

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CA3252232A1 (en) * 2022-05-19 2023-11-23 Chinook Therapeutics, Inc. METHODS OF TREATMENT OF SEGMENTAL AND FOCAL GLOMERULOSCLEROSIS WITH ATRASENTAN
WO2024073672A1 (en) 2022-09-30 2024-04-04 Travere Therapeutics, Inc. Combination therapy with sparsentan and a sglt2 inhibitor for treating kidney diseases or disorders
IL320469A (en) * 2022-10-28 2025-06-01 Chinook Therapeutics Inc Treatment of IGA nephropathy with an endothelin receptor antagonist and an APRIL-binding antibody
AU2023378052A1 (en) 2022-11-07 2025-05-29 Chinook Therapeutics, Inc. Combination of endothelin receptor antagonist and glucocorticoid for treating iga nephropathy

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Also Published As

Publication number Publication date
KR20230015874A (ko) 2023-01-31
CN116173014A (zh) 2023-05-30
JP2023507739A (ja) 2023-02-27
WO2021126977A1 (en) 2021-06-24
US20210353593A1 (en) 2021-11-18
US20230129646A1 (en) 2023-04-27
US11998526B2 (en) 2024-06-04
CN113272013A (zh) 2021-08-17
WO2021126977A9 (en) 2021-07-22
US20220288027A1 (en) 2022-09-15
US20240108599A1 (en) 2024-04-04
JP2025060686A (ja) 2025-04-10
US12370174B2 (en) 2025-07-29
IL293921A (en) 2022-08-01
US20220288026A1 (en) 2022-09-15
TW202130350A (zh) 2021-08-16
EP4076652A1 (en) 2022-10-26
US20230355580A1 (en) 2023-11-09
US20220304978A1 (en) 2022-09-29
EP4076652A4 (en) 2024-01-03
CA3161516A1 (en) 2021-06-24
MX2022007471A (es) 2022-08-17
US20230364055A1 (en) 2023-11-16
US20250281454A1 (en) 2025-09-11
AU2020404984A1 (en) 2022-07-14
US11491137B2 (en) 2022-11-08
JP7624995B2 (ja) 2025-01-31
US20250120945A1 (en) 2025-04-17
EP4076652B1 (en) 2025-12-03
US20230355579A1 (en) 2023-11-09
PH12022551456A1 (en) 2023-10-23
TWI875895B (zh) 2025-03-11
US12121509B2 (en) 2024-10-22
CN116327758A (zh) 2023-06-27

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