BR112022008092A2 - Métodos de preparação de uma amostra enriquecida para sequenciamento polipeptídico - Google Patents
Métodos de preparação de uma amostra enriquecida para sequenciamento polipeptídicoInfo
- Publication number
- BR112022008092A2 BR112022008092A2 BR112022008092A BR112022008092A BR112022008092A2 BR 112022008092 A2 BR112022008092 A2 BR 112022008092A2 BR 112022008092 A BR112022008092 A BR 112022008092A BR 112022008092 A BR112022008092 A BR 112022008092A BR 112022008092 A2 BR112022008092 A2 BR 112022008092A2
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- enriched sample
- preparation
- polypeptide sequencing
- sequencing
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 229920001184 polypeptide Polymers 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 238000012163 sequencing technique Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6818—Sequencing of polypeptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962926897P | 2019-10-28 | 2019-10-28 | |
| PCT/US2020/057638 WO2021086901A1 (en) | 2019-10-28 | 2020-10-28 | Methods of preparing an enriched sample for polypeptide sequencing |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112022008092A2 true BR112022008092A2 (pt) | 2022-07-12 |
Family
ID=73544294
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112022008092A BR112022008092A2 (pt) | 2019-10-28 | 2020-10-28 | Métodos de preparação de uma amostra enriquecida para sequenciamento polipeptídico |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20210148921A1 (enExample) |
| EP (1) | EP4045684A1 (enExample) |
| JP (1) | JP2023500477A (enExample) |
| KR (1) | KR20220108053A (enExample) |
| CN (1) | CN114929897A (enExample) |
| AU (1) | AU2020374879A1 (enExample) |
| BR (1) | BR112022008092A2 (enExample) |
| CA (1) | CA3159357A1 (enExample) |
| MX (1) | MX2022005091A (enExample) |
| WO (1) | WO2021086901A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI863941B (zh) | 2018-11-15 | 2024-12-01 | 美商寬騰矽公司 | 用於蛋白質定序之方法及組合物 |
| EP4051903A1 (en) | 2019-10-29 | 2022-09-07 | Quantum-Si Incorporated | Peristaltic pumping of fluids and associated methods, systems, and devices |
| AU2021276522A1 (en) | 2020-05-20 | 2023-01-05 | Quantum-Si Incorporated | Methods and compositions for protein sequencing |
| CN113512598B (zh) * | 2020-12-07 | 2024-03-22 | 上海仁度生物科技股份有限公司 | 百日咳杆菌的实时荧光核酸恒温扩增检测试剂盒及其专用引物和探针 |
| CN114437993B (zh) * | 2022-03-10 | 2023-07-18 | 中国农业科学院农产品加工研究所 | 罗伊氏乳杆菌及其在制备预防猫腹泻制剂中的应用 |
| WO2024086832A1 (en) * | 2022-10-21 | 2024-04-25 | Quantum-Si Incorporated | Polypeptide cleaving reagents and uses thereof |
| CN115798576B (zh) * | 2023-02-06 | 2023-06-02 | 中国医学科学院北京协和医院 | 一种预测克雷伯氏菌属对亚胺培南敏感性的系统及方法 |
| CN116726156A (zh) * | 2023-03-20 | 2023-09-12 | 西北农林科技大学 | 一种口服酵母介导的产气荚膜梭菌α毒素重组DNA疫苗 |
| CN118173169B (zh) * | 2024-03-28 | 2024-11-26 | 杭州洛兮医学检验实验室有限公司 | 一种检测肺炎支原体及其23S rRNA基因耐药突变的生物信息分析方法 |
| CN118109435B (zh) * | 2024-04-12 | 2025-07-15 | 天津法莫西生物医药科技有限公司 | 一种o-甲基转移酶突变体及其制备方法与应用 |
| CN118600027B (zh) * | 2024-06-17 | 2025-04-18 | 广东生态工程职业学院 | 一种与鹦鹉精子活力和受精率相关的miRNA及其应用 |
| CN119185551B (zh) * | 2024-11-06 | 2025-05-27 | 浙江安吉吉检医疗科技有限公司 | 一种基于细菌dna旋转酶凝聚体的细菌药物靶点及药物 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2496294A1 (en) | 2005-02-07 | 2006-08-07 | The University Of British Columbia | Apparatus and methods for concentrating and separating particles such as molecules |
| WO2007123708A2 (en) * | 2006-03-31 | 2007-11-01 | Epitome Biosystems, Inc. | Post translational modification pattern analysis |
| WO2010044892A1 (en) * | 2008-10-17 | 2010-04-22 | President And Fellows Of Harvard College | Diagnostic method based on large scale identification of post-translational modification of proteins |
| US9566335B1 (en) * | 2009-09-25 | 2017-02-14 | The Governing Council Of The University Of Toronto | Protein sequencing method and reagents |
| DK3011051T3 (en) * | 2013-06-21 | 2019-04-23 | Sequenom Inc | Method for non-invasive evaluation of genetic variations |
| WO2016193980A1 (en) * | 2015-06-03 | 2016-12-08 | Bar Ilan University | Methods and kits for detection and quantification of large-scale post translational modifications of proteins |
| MX2020004559A (es) * | 2017-10-31 | 2020-10-05 | Encodia Inc | Kits para análisis utilizando codificación y/o etiqueta de ácido nucleico. |
| WO2020023488A1 (en) * | 2018-07-23 | 2020-01-30 | Board Of Regents, The University Of Texas System | Single molecule sequencing identification of post-translational modifications on proteins |
| EP3966824A1 (en) * | 2019-06-12 | 2022-03-16 | Quantum-Si Incorporated | Techniques for protein identification using machine learning and related systems and methods |
| US20210354134A1 (en) * | 2020-04-22 | 2021-11-18 | Quantum-Si Incorporated | Sample preparation for sequencing |
-
2020
- 2020-10-28 KR KR1020227017589A patent/KR20220108053A/ko not_active Ceased
- 2020-10-28 CA CA3159357A patent/CA3159357A1/en active Pending
- 2020-10-28 BR BR112022008092A patent/BR112022008092A2/pt not_active Application Discontinuation
- 2020-10-28 WO PCT/US2020/057638 patent/WO2021086901A1/en not_active Ceased
- 2020-10-28 AU AU2020374879A patent/AU2020374879A1/en not_active Abandoned
- 2020-10-28 JP JP2022525080A patent/JP2023500477A/ja not_active Withdrawn
- 2020-10-28 CN CN202080091893.9A patent/CN114929897A/zh active Pending
- 2020-10-28 MX MX2022005091A patent/MX2022005091A/es unknown
- 2020-10-28 EP EP20811813.3A patent/EP4045684A1/en not_active Withdrawn
- 2020-10-28 US US17/082,899 patent/US20210148921A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP4045684A1 (en) | 2022-08-24 |
| CA3159357A1 (en) | 2021-05-06 |
| CN114929897A (zh) | 2022-08-19 |
| JP2023500477A (ja) | 2023-01-06 |
| KR20220108053A (ko) | 2022-08-02 |
| US20210148921A1 (en) | 2021-05-20 |
| WO2021086901A1 (en) | 2021-05-06 |
| AU2020374879A1 (en) | 2022-06-02 |
| MX2022005091A (es) | 2022-08-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CO2022000660A2 (es) | Composiciones de proteína anti-vegf y métodos para producir la misma | |
| MX2022005091A (es) | Metodos de preparacion de una muestra enriquecida para la secuenciacion de polipeptidos. | |
| EA202090090A1 (ru) | Включение неприродных нуклеотидов и способы с ними | |
| ECSP18023386A (es) | Moléculas de unión a linfopoyetina estromal timica (tslp) y métodos de uso de las moléculas | |
| CO2018002446A2 (es) | Moléculas de unión a linfopoyetina estromal timica (tslp) y métodos de uso de las moléculas | |
| BR122020006918B8 (pt) | Anticorpo de domínio único anti-stat3 e seu uso, métodos in vitro para medir os níveis do referido anticorpo e para diagnosticar um distúrbio mediado por um componente intracelular, polipeptídeo isolado e composição compreendendo o referido anticorpo ou polipeptídeo isolado | |
| BR112018003127A2 (pt) | purificação de fkpa e usos do mesmo para produzir polipeptídeos recombinantes | |
| CO2023017156A2 (es) | Anticuerpos anti-sirp-alfa | |
| BR112017001417A2 (pt) | variantes de proteína de ligação ao fator h e métodos para uso das mesmas | |
| CO2019013718A2 (es) | Anticuerpos anti-trkb | |
| BR112016026842A2 (pt) | preparação compreendendo fator viii e peptídeos de fator de von willebrand | |
| CL2021001615A1 (es) | Anticuerpos anti il-36 y procedimientos de uso de estos | |
| BR112018015965A2 (pt) | método para determinação de helicobacter pylori | |
| BR112022012731A2 (pt) | Anticorpo anti-ox40 e uso do mesmo | |
| EA202191403A1 (ru) | Композиция с высокой концентрацией белка | |
| EA201992317A1 (ru) | Композиции и способы для диагностики рака легких | |
| MX372810B (es) | Composiciones de wnt y metodos para purificacion. | |
| EA201890177A1 (ru) | Мультиспецифические связывающие белки | |
| BR112017027729A2 (pt) | indução de expressão de gene com o uso de uma mistura de açúcar de concentração alta | |
| JOP20210339A1 (ar) | أجسام مضادة لـ angpt2 | |
| MX2021015879A (es) | Peptidos restringidos. | |
| HK40079624A (en) | Methods of preparing an enriched sample for polypeptide sequencing | |
| PL427190A1 (pl) | Fosfoorganiczne pochodne peptydowe będące analogami N-końcowej sekwencji białka Smac, sposób ich wytwarzania oraz ich zastosowanie | |
| BR112018009319A8 (pt) | polipeptídeos de fusobacterium e métodos de uso |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |