BR112022008092A2 - Métodos de preparação de uma amostra enriquecida para sequenciamento polipeptídico - Google Patents

Métodos de preparação de uma amostra enriquecida para sequenciamento polipeptídico

Info

Publication number
BR112022008092A2
BR112022008092A2 BR112022008092A BR112022008092A BR112022008092A2 BR 112022008092 A2 BR112022008092 A2 BR 112022008092A2 BR 112022008092 A BR112022008092 A BR 112022008092A BR 112022008092 A BR112022008092 A BR 112022008092A BR 112022008092 A2 BR112022008092 A2 BR 112022008092A2
Authority
BR
Brazil
Prior art keywords
methods
enriched sample
preparation
polypeptide sequencing
sequencing
Prior art date
Application number
BR112022008092A
Other languages
English (en)
Inventor
Reed Brian
Dyer Matthew
Original Assignee
Quantum Si Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quantum Si Inc filed Critical Quantum Si Inc
Publication of BR112022008092A2 publication Critical patent/BR112022008092A2/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6818—Sequencing of polypeptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

MÉTODOS DE PREPARAÇÃO DE UMA AMOSTRA ENRIQUECIDA PARA SEQUENCIAMENTO POLIPEPTÍDICO. A presente invenção refere-se a métodos de preparação de uma amostra enriquecida para sequenciamento de polipeptídeos e composições, kits e dispositivos úteis para o mesmo.
BR112022008092A 2019-10-28 2020-10-28 Métodos de preparação de uma amostra enriquecida para sequenciamento polipeptídico BR112022008092A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962926897P 2019-10-28 2019-10-28
PCT/US2020/057638 WO2021086901A1 (en) 2019-10-28 2020-10-28 Methods of preparing an enriched sample for polypeptide sequencing

Publications (1)

Publication Number Publication Date
BR112022008092A2 true BR112022008092A2 (pt) 2022-07-12

Family

ID=73544294

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022008092A BR112022008092A2 (pt) 2019-10-28 2020-10-28 Métodos de preparação de uma amostra enriquecida para sequenciamento polipeptídico

Country Status (10)

Country Link
US (1) US20210148921A1 (pt)
EP (1) EP4045684A1 (pt)
JP (1) JP2023500477A (pt)
KR (1) KR20220108053A (pt)
CN (1) CN114929897A (pt)
AU (1) AU2020374879A1 (pt)
BR (1) BR112022008092A2 (pt)
CA (1) CA3159357A1 (pt)
MX (1) MX2022005091A (pt)
WO (1) WO2021086901A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202032125A (zh) 2018-11-15 2020-09-01 美商寬騰矽公司 用於蛋白質定序之方法及組合物
CN113512598B (zh) * 2020-12-07 2024-03-22 上海仁度生物科技股份有限公司 百日咳杆菌的实时荧光核酸恒温扩增检测试剂盒及其专用引物和探针
CN114437993B (zh) * 2022-03-10 2023-07-18 中国农业科学院农产品加工研究所 罗伊氏乳杆菌及其在制备预防猫腹泻制剂中的应用
WO2024086832A1 (en) * 2022-10-21 2024-04-25 Quantum-Si Incorporated Polypeptide cleaving reagents and uses thereof
CN115798576B (zh) * 2023-02-06 2023-06-02 中国医学科学院北京协和医院 一种预测克雷伯氏菌属对亚胺培南敏感性的系统及方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2496294A1 (en) 2005-02-07 2006-08-07 The University Of British Columbia Apparatus and methods for concentrating and separating particles such as molecules
WO2007123708A2 (en) * 2006-03-31 2007-11-01 Epitome Biosystems, Inc. Post translational modification pattern analysis
WO2010044892A1 (en) * 2008-10-17 2010-04-22 President And Fellows Of Harvard College Diagnostic method based on large scale identification of post-translational modification of proteins
US9566335B1 (en) * 2009-09-25 2017-02-14 The Governing Council Of The University Of Toronto Protein sequencing method and reagents
KR102299305B1 (ko) * 2013-06-21 2021-09-06 시쿼넘, 인코포레이티드 유전적 변이의 비침습 평가를 위한 방법 및 프로세스
WO2016193980A1 (en) * 2015-06-03 2016-12-08 Bar Ilan University Methods and kits for detection and quantification of large-scale post translational modifications of proteins
KR102556494B1 (ko) * 2017-10-31 2023-07-18 엔코디아, 인코포레이티드 핵산 암호화 및/또는 표지를 이용한 분석용 키트
JP2021530549A (ja) * 2018-07-23 2021-11-11 ボード オブ リージェンツ, ザ ユニバーシティ オブ テキサス システムBoard Of Regents, The University Of Texas System タンパク質における翻訳後修飾の、単一分子配列決定による同定
KR20220019778A (ko) * 2019-06-12 2022-02-17 퀀텀-에스아이 인코포레이티드 머신 학습을 이용한 단백질 식별을 위한 기법들 및 관련된 시스템들 및 방법들
US20210354134A1 (en) * 2020-04-22 2021-11-18 Quantum-Si Incorporated Sample preparation for sequencing

Also Published As

Publication number Publication date
CA3159357A1 (en) 2021-05-06
US20210148921A1 (en) 2021-05-20
AU2020374879A1 (en) 2022-06-02
JP2023500477A (ja) 2023-01-06
EP4045684A1 (en) 2022-08-24
CN114929897A (zh) 2022-08-19
WO2021086901A1 (en) 2021-05-06
KR20220108053A (ko) 2022-08-02
MX2022005091A (es) 2022-08-11

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B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]