BR112022004419A2 - Partículas de núcleo-casca de liberação controlada e suspensões incluindo as mesmas - Google Patents

Partículas de núcleo-casca de liberação controlada e suspensões incluindo as mesmas

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Publication number
BR112022004419A2
BR112022004419A2 BR112022004419A BR112022004419A BR112022004419A2 BR 112022004419 A2 BR112022004419 A2 BR 112022004419A2 BR 112022004419 A BR112022004419 A BR 112022004419A BR 112022004419 A BR112022004419 A BR 112022004419A BR 112022004419 A2 BR112022004419 A2 BR 112022004419A2
Authority
BR
Brazil
Prior art keywords
controlled release
same
core
polymer
active ingredient
Prior art date
Application number
BR112022004419A
Other languages
English (en)
Inventor
Ehsan Moaseri
Original Assignee
Nulixir Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nulixir Inc filed Critical Nulixir Inc
Publication of BR112022004419A2 publication Critical patent/BR112022004419A2/pt

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    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
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Abstract

artículas de núcleo-casca de liberação controlada e suspensões incluindo as mesmas. a presente invenção refere-se a uma composição incluindo um meio de dispersão incluindo: uma solução aquosa; um primeiro ingrediente ativo; um agente aromatizante; e um primeiro tipo de polímero; e uma fase dispersa incluindo: uma população de partículas, cada partícula incluindo: um núcleo incluindo: um segundo ingrediente ativo, um segundo tipo de polímero; e uma solução aquosa; uma casca, envolvendo substancialmente o núcleo, a casca incluindo: um terceiro tipo de polímero; uma pluralidade de veículos lipofílicos; e um terceiro ingrediente ativo; e uma pluralidade de agentes emulsificantes.
BR112022004419A 2019-09-12 2020-09-14 Partículas de núcleo-casca de liberação controlada e suspensões incluindo as mesmas BR112022004419A2 (pt)

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US201962899595P 2019-09-12 2019-09-12
US201962944912P 2019-12-06 2019-12-06
US202062968591P 2020-01-31 2020-01-31
US202063012058P 2020-04-17 2020-04-17
PCT/US2020/050772 WO2021051105A2 (en) 2019-09-12 2020-09-14 Controlled release core-shell particles and suspensions including the same

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