BR112022003258A2 - Processos de extração e purificação à base de água para ácidos canabinoides - Google Patents

Processos de extração e purificação à base de água para ácidos canabinoides

Info

Publication number
BR112022003258A2
BR112022003258A2 BR112022003258A BR112022003258A BR112022003258A2 BR 112022003258 A2 BR112022003258 A2 BR 112022003258A2 BR 112022003258 A BR112022003258 A BR 112022003258A BR 112022003258 A BR112022003258 A BR 112022003258A BR 112022003258 A2 BR112022003258 A2 BR 112022003258A2
Authority
BR
Brazil
Prior art keywords
cannabinoid acids
water
based extraction
purification processes
cannabinoid
Prior art date
Application number
BR112022003258A
Other languages
English (en)
Inventor
Mccaslin Carraher Jack
Joseph BAKER Zach
Original Assignee
Medpharm Iowa Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medpharm Iowa Llc filed Critical Medpharm Iowa Llc
Publication of BR112022003258A2 publication Critical patent/BR112022003258A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/50—Use of additives, e.g. for stabilisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/02—Preparation of carboxylic acids or their salts, halides or anhydrides from salts of carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/43—Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation
    • C07C51/44—Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation by distillation
    • C07C51/445—Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation by distillation by steam distillation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/47—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/48—Separation; Purification; Stabilisation; Use of additives by liquid-liquid treatment
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

processos de extração e purificação à base de água para ácidos canabinoides. a presente invenção se refere a métodos de extração de ácidos canabinoides de material vegetal de cannabis combinando o material vegetal com uma solução aquosa com um ph alto para solubilizar ânions de ácido canabinoide, seguido por precipitação dos ácidos canabinoides em ph baixo e filtração. o método fornece rendimentos de até 97%, enquanto a purificação de alto ph de óleos extraídos com etanol rendeu purezas de até 86%.
BR112022003258A 2019-08-22 2020-08-14 Processos de extração e purificação à base de água para ácidos canabinoides BR112022003258A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962890355P 2019-08-22 2019-08-22
PCT/US2020/046524 WO2021034718A1 (en) 2019-08-22 2020-08-14 Water-based extraction and purification processes for cannabinoid acids

Publications (1)

Publication Number Publication Date
BR112022003258A2 true BR112022003258A2 (pt) 2022-05-17

Family

ID=74647138

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022003258A BR112022003258A2 (pt) 2019-08-22 2020-08-14 Processos de extração e purificação à base de água para ácidos canabinoides

Country Status (5)

Country Link
US (1) US11623909B2 (pt)
EP (1) EP4017483A4 (pt)
BR (1) BR112022003258A2 (pt)
CA (1) CA3150781A1 (pt)
WO (1) WO2021034718A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210370198A1 (en) * 2020-05-29 2021-12-02 Chemtor, Lp Purification and extraction of cannabinoids
US20220317097A1 (en) * 2021-04-05 2022-10-06 Grant Kraus Atmospheric Triphasic Chromatography (ATC) method
WO2023047396A1 (en) * 2021-09-22 2023-03-30 Roxx Labs Ltd. Concentrated aqueous cannabinoid compositions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2806034T3 (es) * 2011-09-29 2021-02-16 Thc Pharm Gmbh The Health Concept Acidos carboxílicos de cannabinoide, sales de ácidos carboxílicos de cannabinoide, su preparación y aplicaciones
BG112018A (bg) 2015-05-22 2016-11-30 "Побелч-Гле" Оод Метод за получаване на канабиноиден извлек от коноп
US10382592B2 (en) 2017-07-12 2019-08-13 Juniper Networks, Inc. Segment routing label switched path for non-segment routing enabled routers
IT201700085508A1 (it) * 2017-07-26 2019-01-26 Inalco S R L Metodo per la produzione di cannabinoidi da varietà di canapa industriale
WO2019100172A1 (en) 2017-11-27 2019-05-31 Beleave Inc. Extraction and purification of cannabinoid compounds
US10941102B2 (en) * 2017-11-29 2021-03-09 Robert Henry Wohleb Aqueous leaching method to produce microcrystalline powder

Also Published As

Publication number Publication date
WO2021034718A1 (en) 2021-02-25
US20210053902A1 (en) 2021-02-25
CA3150781A1 (en) 2021-02-25
EP4017483A1 (en) 2022-06-29
US11623909B2 (en) 2023-04-11
EP4017483A4 (en) 2023-09-20

Similar Documents

Publication Publication Date Title
BR112022003258A2 (pt) Processos de extração e purificação à base de água para ácidos canabinoides
BR112016028273A8 (pt) derivados radiorrotulados de composto de 2-amino6-fluoro-n-[5-fluoro-piridin-3-il]-pirazol[1,5-a]pirimidin3-carboxamida úteis como inibidor de atr cinase, processo para preparação do referido composto, bem como diferentes formas sólidas do mesmo, uso destas, e composição farmacêutica
BR112017025913A2 (pt) processo para preparação de uma composição de ácido purificado.
BR112022010664A2 (pt) Derivados de um inibidor de fgfr
BR112012019413A2 (pt) processo para producao de uma corrente de alimentacao de ester para producao de esteres e coproducao de etanol
EA201892173A1 (ru) Фармацевтический состав палбоциклиба и способ его получения
BR112016006151A2 (pt) imidazopiridazinas úteis como inibidores da via de sinalização do par-2
CU20200084A7 (es) Derivados sustituidos de la carboxamida dihidropirazolo pirazina
BRPI0922774B8 (pt) composto cloridrato de nelmefeno di-hidratado, sua composição farmacêutica e processos de obtenção e produção dos mesmos.
EA201990455A1 (ru) КОНДЕНСИРОВАННОЕ ТРИЦИКЛИЧЕСКОЕ ПРОИЗВОДНОЕ γ-АМИНОКИСЛОТЫ, СПОСОБ ЕГО ПОЛУЧЕНИЯ И ЕГО МЕДИЦИНСКОЕ ПРИМЕНЕНИЕ
MX2018001145A (es) Métodos para la preparación de ácidos biliares y derivados de los mismos.
BR112014013098A2 (pt) composições compreendendo ácidos graxos que têm 20 carbonos e métodos de produção e uso dos mesmos
BR112014000837A2 (pt) aparelho para a produção de aços recozidos e processo para a produção dos ditos aços
WO2016185211A8 (en) Process for the biological production of methacrylic acid and derivatives thereof
IN2014CN02188A (pt)
BR112015014895A2 (pt) processo para produção de produtos de biomassa
MX2021011401A (es) Metodo para la deteccion y cuantificacion de fosfomicina y de sus impurezas y/o productos de degradacion.
BR112021019072A2 (pt) Processo para enriquecimento de carotenoides em uma composição de ácido graxo
MX369556B (es) Procesos para la preparacion de derivados acidos de n-acetilgalactosamina (galnac).
WO2016142819A3 (en) Novel process for the preparation of ranolazine
MA37112A1 (fr) Nouveau procede d'extraction et de purification de cannabinoides
WO2020197059A3 (ko) 엽산, 엽산 유도체, 또는 엽산 저해제를 이용한 줄기세포의 연골세포로의 분화 유도 방법
WO2006101922A3 (en) Medicinal compositions of salts, chelates and/or free acids of alpha hydroxyl organic acids and related processes and methods
WO2020214100A3 (en) Composition
BR112012014416A2 (pt) novos derivados de dioxolanos e de dioxanos, e método para sua produção.