BR112021025330A2 - Metiltioninio como intensificador da função cognitiva - Google Patents
Metiltioninio como intensificador da função cognitivaInfo
- Publication number
- BR112021025330A2 BR112021025330A2 BR112021025330A BR112021025330A BR112021025330A2 BR 112021025330 A2 BR112021025330 A2 BR 112021025330A2 BR 112021025330 A BR112021025330 A BR 112021025330A BR 112021025330 A BR112021025330 A BR 112021025330A BR 112021025330 A2 BR112021025330 A2 BR 112021025330A2
- Authority
- BR
- Brazil
- Prior art keywords
- methylthioninium
- cognitive function
- function enhancer
- enhancer
- cognitive
- Prior art date
Links
- RBTBFTRPCNLSDE-UHFFFAOYSA-N 3,7-bis(dimethylamino)phenothiazin-5-ium Chemical compound C1=CC(N(C)C)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 RBTBFTRPCNLSDE-UHFFFAOYSA-N 0.000 title abstract 2
- 230000003920 cognitive function Effects 0.000 title abstract 2
- 239000003623 enhancer Substances 0.000 title abstract 2
- 206010012289 Dementia Diseases 0.000 abstract 1
- QTWZICCBKBYHDM-UHFFFAOYSA-P [7-(dimethylazaniumyl)-10H-phenothiazin-3-yl]-dimethylazanium Chemical compound C[NH+](C)c1ccc2Nc3ccc(cc3Sc2c1)[NH+](C)C QTWZICCBKBYHDM-UHFFFAOYSA-P 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000037410 cognitive enhancement Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000001777 nootropic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D25/00—Details of other kinds or types of rigid or semi-rigid containers
- B65D25/34—Coverings or external coatings
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
- B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
- B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
- B65D75/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
- B65D75/36—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet or blank being recessed and the other formed of relatively stiff flat sheet material, e.g. blister packages, the recess or recesses being preformed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/03—Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
- A61J1/035—Blister-type containers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D2203/00—Decoration means, markings, information elements, contents indicators
- B65D2203/02—Labels
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hospice & Palliative Care (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Organic Chemistry (AREA)
- Mechanical Engineering (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Food Science & Technology (AREA)
- Composite Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Physiology (AREA)
- Medicinal Preparation (AREA)
Abstract
metiltioninio como intensificador da função cognitiva. a presente invenção refere-se geralmente às composições nootrópicas, compreendendo sais de ácido leuco-metiltionínio, e seus usos para a aprimoramento cognitivo em indivíduos normais (não dementes).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1909454.9A GB201909454D0 (en) | 2019-07-01 | 2019-07-01 | Enhancers |
PCT/EP2020/068229 WO2021001306A1 (en) | 2019-07-01 | 2020-06-29 | Methylthioninium as enhancers of the cognitive function |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112021025330A2 true BR112021025330A2 (pt) | 2022-02-01 |
Family
ID=67539959
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112021025330A BR112021025330A2 (pt) | 2019-07-01 | 2020-06-29 | Metiltioninio como intensificador da função cognitiva |
Country Status (12)
Country | Link |
---|---|
US (1) | US20220330594A1 (pt) |
EP (1) | EP3989977A1 (pt) |
JP (1) | JP2022539185A (pt) |
KR (1) | KR20220028045A (pt) |
CN (1) | CN114096254A (pt) |
AU (1) | AU2020298737A1 (pt) |
BR (1) | BR112021025330A2 (pt) |
CA (1) | CA3143417A1 (pt) |
GB (1) | GB201909454D0 (pt) |
IL (1) | IL289341A (pt) |
MX (1) | MX2021015289A (pt) |
WO (1) | WO2021001306A1 (pt) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2912571T3 (es) | 2006-07-11 | 2022-05-26 | Wista Lab Ltd | Procedimientos de síntesis y/o de purificación de compuestos de diaminofenotiazinio |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0100119D0 (en) | 2001-01-03 | 2001-02-14 | Univ Aberdeen | Materials and methods relating to protein aggregation in neurodegenerative disease |
PT2013191E (pt) | 2006-03-29 | 2010-10-29 | Wista Lab Ltd | Sais de 3,7-diamino-10h-fenotiazina e a sua utilização |
PT2167095T (pt) | 2007-06-19 | 2019-08-06 | Wista Lab Ltd | Compostos de fenotiazina para o tratamento de comprometimento cognitivo leve |
PL2205245T3 (pl) | 2007-10-03 | 2015-12-31 | Wista Lab Ltd | Zastosowanie terapeutyczne diaminofenotiazyn |
US9283230B2 (en) | 2011-02-11 | 2016-03-15 | Wista Laboratories Ltd. | Phenothiazine diaminium salts and their use |
EP2705841A1 (en) | 2012-09-05 | 2014-03-12 | Pharnext | Combinations of nootropic agents for treating cognitive dysfunctions |
KR102475825B1 (ko) | 2016-07-25 | 2022-12-08 | 위스타 레보레이토리스 리미티드 | 디아미노페노티아진 (diaminophenothiazines)의 투여 및 투여량 (dosage) |
GB201614834D0 (en) | 2016-09-01 | 2016-10-19 | Wista Lab Ltd | Treatment of dementia |
-
2019
- 2019-07-01 GB GBGB1909454.9A patent/GB201909454D0/en not_active Ceased
-
2020
- 2020-06-29 EP EP20735367.3A patent/EP3989977A1/en active Pending
- 2020-06-29 CA CA3143417A patent/CA3143417A1/en active Pending
- 2020-06-29 US US17/620,956 patent/US20220330594A1/en active Pending
- 2020-06-29 WO PCT/EP2020/068229 patent/WO2021001306A1/en unknown
- 2020-06-29 BR BR112021025330A patent/BR112021025330A2/pt unknown
- 2020-06-29 KR KR1020227003214A patent/KR20220028045A/ko unknown
- 2020-06-29 AU AU2020298737A patent/AU2020298737A1/en active Pending
- 2020-06-29 MX MX2021015289A patent/MX2021015289A/es unknown
- 2020-06-29 CN CN202080048926.1A patent/CN114096254A/zh active Pending
- 2020-06-29 JP JP2021577642A patent/JP2022539185A/ja active Pending
-
2021
- 2021-12-23 IL IL289341A patent/IL289341A/en unknown
Also Published As
Publication number | Publication date |
---|---|
JP2022539185A (ja) | 2022-09-07 |
KR20220028045A (ko) | 2022-03-08 |
AU2020298737A1 (en) | 2022-02-24 |
CN114096254A (zh) | 2022-02-25 |
US20220330594A1 (en) | 2022-10-20 |
EP3989977A1 (en) | 2022-05-04 |
IL289341A (en) | 2022-02-01 |
CA3143417A1 (en) | 2021-01-07 |
GB201909454D0 (en) | 2019-08-14 |
WO2021001306A1 (en) | 2021-01-07 |
MX2021015289A (es) | 2022-01-18 |
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