BR112018071722A2 - uso do amino açúcar como plastificante - Google Patents
uso do amino açúcar como plastificanteInfo
- Publication number
- BR112018071722A2 BR112018071722A2 BR112018071722A BR112018071722A BR112018071722A2 BR 112018071722 A2 BR112018071722 A2 BR 112018071722A2 BR 112018071722 A BR112018071722 A BR 112018071722A BR 112018071722 A BR112018071722 A BR 112018071722A BR 112018071722 A2 BR112018071722 A2 BR 112018071722A2
- Authority
- BR
- Brazil
- Prior art keywords
- plasticizer
- amino sugar
- treatment
- formulated
- formulations
- Prior art date
Links
- 150000002337 glycosamines Chemical class 0.000 title abstract 2
- 239000004014 plasticizer Substances 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 238000001125 extrusion Methods 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000000155 melt Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C48/00—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
- B29C48/022—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor characterised by the choice of material
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/12—Powdering or granulating
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K5/00—Use of organic ingredients
- C08K5/0008—Organic ingredients according to more than one of the "one dot" groups of C08K5/01 - C08K5/59
- C08K5/0016—Plasticisers
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K5/00—Use of organic ingredients
- C08K5/0008—Organic ingredients according to more than one of the "one dot" groups of C08K5/01 - C08K5/59
- C08K5/005—Stabilisers against oxidation, heat, light, ozone
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K5/00—Use of organic ingredients
- C08K5/16—Nitrogen-containing compounds
- C08K5/17—Amines; Quaternary ammonium compounds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L29/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical; Compositions of hydrolysed polymers of esters of unsaturated alcohols with saturated carboxylic acids; Compositions of derivatives of such polymers
- C08L29/02—Homopolymers or copolymers of unsaturated alcohols
- C08L29/04—Polyvinyl alcohol; Partially hydrolysed homopolymers or copolymers of esters of unsaturated alcohols with saturated carboxylic acids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2029/00—Use of polyvinylalcohols, polyvinylethers, polyvinylaldehydes, polyvinylketones or polyvinylketals or derivatives thereof as moulding material
- B29K2029/04—PVOH, i.e. polyvinyl alcohol
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2329/00—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal, or ketal radical; Hydrolysed polymers of esters of unsaturated alcohols with saturated carboxylic acids; Derivatives of such polymer
- C08J2329/02—Homopolymers or copolymers of unsaturated alcohols
- C08J2329/04—Polyvinyl alcohol; Partially hydrolysed homopolymers or copolymers of esters of unsaturated alcohols with saturated carboxylic acids
Abstract
a presente invenção refere-se ao de um amino açúcar como plastificante em formulações compreendendo um polímero como veículo para ingredientes ativos, em particular para composições que são in-tensamente misturadas por tratamento em uma extrusão por fusão e então formuladas por pós-tratamento adequado.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP16169691 | 2016-05-13 | ||
EP16169691.9 | 2016-05-13 | ||
PCT/EP2017/061127 WO2017194577A1 (en) | 2016-05-13 | 2017-05-10 | Use of amino sugar as plasticizer |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112018071722A2 true BR112018071722A2 (pt) | 2019-02-19 |
BR112018071722B1 BR112018071722B1 (pt) | 2024-02-27 |
Family
ID=55969048
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112018071722-3A BR112018071722B1 (pt) | 2016-05-13 | 2017-05-10 | Uso do amino açúcar como plastificante, composição em pó e seu processo de produção |
Country Status (13)
Country | Link |
---|---|
US (1) | US11045550B2 (pt) |
EP (1) | EP3454837B1 (pt) |
JP (1) | JP7000348B2 (pt) |
KR (1) | KR102388870B1 (pt) |
CN (1) | CN109195588B (pt) |
BR (1) | BR112018071722B1 (pt) |
CA (1) | CA3023795C (pt) |
DK (1) | DK3454837T3 (pt) |
IL (1) | IL262907B2 (pt) |
MX (1) | MX2018012998A (pt) |
PH (1) | PH12018502105A1 (pt) |
SG (1) | SG11201809970UA (pt) |
WO (1) | WO2017194577A1 (pt) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6216675B2 (ja) * | 2014-03-31 | 2017-10-18 | 株式会社クラレ | スラリー用添加剤、掘削泥水及びセメントスラリー |
EP3928765A1 (en) * | 2018-04-16 | 2021-12-29 | Merck Patent GmbH | Viscosity reduction of highly concentrated protein formulations |
CA3108304A1 (en) * | 2018-06-21 | 2019-12-26 | Aquestive Therapeutics, Inc. | System and method for making personalized individual unit doses containing pharmaceutical actives |
JP2020090456A (ja) * | 2018-12-05 | 2020-06-11 | 日本化薬株式会社 | エルロチニブを有効成分とする医薬錠剤 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0580860B2 (en) | 1991-04-16 | 2004-12-15 | Nippon Shinyaku Company, Limited | Method of manufacturing solid dispersion |
CN1039648C (zh) * | 1991-08-01 | 1998-09-02 | 诺瓦蒙特股份公司 | 可得自含变构淀粉和热塑性聚合物的熔体的聚合物组合物 |
US7476631B2 (en) * | 2003-04-03 | 2009-01-13 | The Procter & Gamble Company | Dispersible fibrous structure and method of making same |
GB2409204A (en) * | 2003-12-19 | 2005-06-22 | Reckitt Benckiser Nv | Plasticized thermoplastic polymer |
CN101489756B (zh) | 2006-03-24 | 2013-08-07 | 奥克思利尤姆国际控股公司 | 热熔挤出层压材料的制备方法 |
EP2105130A1 (de) | 2008-03-25 | 2009-09-30 | Ratiopharm GmbH | Pharmazeutische Formulierung und Verfahren zu deren Herstellung |
WO2011140446A2 (en) | 2010-05-06 | 2011-11-10 | Dr. Reddy's Laboratories Ltd. | Pharmaceutical formulations |
CN103142501B (zh) * | 2013-03-21 | 2014-10-01 | 青岛正大海尔制药有限公司 | 骨化三醇微丸及其制备方法 |
EP3122337A4 (en) * | 2014-03-26 | 2017-11-08 | Sun Pharma Advanced Research Company Ltd | Abuse deterrent immediate release coated reservoir solid dosage form |
JP5871294B1 (ja) | 2015-02-27 | 2016-03-01 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 即時放出経口錠剤 |
CN105456201B (zh) | 2015-12-08 | 2018-06-01 | 青岛正大海尔制药有限公司 | 氨溴索沙丁胺醇微丸的制备方法 |
-
2017
- 2017-05-10 KR KR1020187035446A patent/KR102388870B1/ko active IP Right Grant
- 2017-05-10 JP JP2018559849A patent/JP7000348B2/ja active Active
- 2017-05-10 CN CN201780028400.5A patent/CN109195588B/zh active Active
- 2017-05-10 CA CA3023795A patent/CA3023795C/en active Active
- 2017-05-10 BR BR112018071722-3A patent/BR112018071722B1/pt active IP Right Grant
- 2017-05-10 EP EP17727496.6A patent/EP3454837B1/en active Active
- 2017-05-10 US US16/301,185 patent/US11045550B2/en active Active
- 2017-05-10 WO PCT/EP2017/061127 patent/WO2017194577A1/en unknown
- 2017-05-10 SG SG11201809970UA patent/SG11201809970UA/en unknown
- 2017-05-10 MX MX2018012998A patent/MX2018012998A/es unknown
- 2017-05-10 DK DK17727496.6T patent/DK3454837T3/da active
- 2017-05-10 IL IL262907A patent/IL262907B2/en unknown
-
2018
- 2018-09-28 PH PH12018502105A patent/PH12018502105A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
PH12018502105A1 (en) | 2019-07-29 |
US20190134200A1 (en) | 2019-05-09 |
CA3023795A1 (en) | 2017-11-16 |
IL262907B2 (en) | 2023-09-01 |
EP3454837B1 (en) | 2022-11-30 |
MX2018012998A (es) | 2019-01-28 |
WO2017194577A1 (en) | 2017-11-16 |
KR20190006992A (ko) | 2019-01-21 |
US11045550B2 (en) | 2021-06-29 |
IL262907B1 (en) | 2023-05-01 |
SG11201809970UA (en) | 2018-12-28 |
CA3023795C (en) | 2024-01-16 |
CN109195588A (zh) | 2019-01-11 |
JP2019518740A (ja) | 2019-07-04 |
BR112018071722B1 (pt) | 2024-02-27 |
KR102388870B1 (ko) | 2022-04-20 |
CN109195588B (zh) | 2022-08-02 |
IL262907A (en) | 2018-12-31 |
EP3454837A1 (en) | 2019-03-20 |
JP7000348B2 (ja) | 2022-01-19 |
DK3454837T3 (da) | 2023-02-27 |
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Legal Events
Date | Code | Title | Description |
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B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06W | Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette] | ||
B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 10/05/2017, OBSERVADAS AS CONDICOES LEGAIS |