BR112021023216A2 - Derivados heterocíclicos fundidos como agentes antivirais - Google Patents

Derivados heterocíclicos fundidos como agentes antivirais

Info

Publication number
BR112021023216A2
BR112021023216A2 BR112021023216A BR112021023216A BR112021023216A2 BR 112021023216 A2 BR112021023216 A2 BR 112021023216A2 BR 112021023216 A BR112021023216 A BR 112021023216A BR 112021023216 A BR112021023216 A BR 112021023216A BR 112021023216 A2 BR112021023216 A2 BR 112021023216A2
Authority
BR
Brazil
Prior art keywords
fused heterocyclic
antiviral agents
heterocyclic derivatives
compounds
derivatives
Prior art date
Application number
BR112021023216A
Other languages
English (en)
Inventor
Chao-Yuan Wang
Martin Berke Jan
Graham Deratt Lindsey
D Kuduk Scott
Original Assignee
Janssen Sciences Ireland Unlimited Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Sciences Ireland Unlimited Co filed Critical Janssen Sciences Ireland Unlimited Co
Publication of BR112021023216A2 publication Critical patent/BR112021023216A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

derivados heterocíclicos fundidos como agentes antivirais. a presente invenção refere-se a compostos de derivados heterocíclicos fundidos, composições farmacêuticas compreendendo estes compostos, processos químicos para preparar estes compostos e seu uso no tratamento de doenças associadas à infecção pelo hbv.
BR112021023216A 2019-05-28 2020-05-27 Derivados heterocíclicos fundidos como agentes antivirais BR112021023216A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962853554P 2019-05-28 2019-05-28
EP19176954 2019-05-28
PCT/US2020/034654 WO2020243142A1 (en) 2019-05-28 2020-05-27 Fused heterocyclic derivatives as antiviral agents

Publications (1)

Publication Number Publication Date
BR112021023216A2 true BR112021023216A2 (pt) 2022-01-04

Family

ID=71523196

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112021023216A BR112021023216A2 (pt) 2019-05-28 2020-05-27 Derivados heterocíclicos fundidos como agentes antivirais

Country Status (10)

Country Link
US (1) US20220323455A1 (pt)
EP (1) EP3976616A1 (pt)
JP (1) JP2022535208A (pt)
KR (1) KR20220012321A (pt)
CN (1) CN113939512A (pt)
AU (1) AU2020285719A1 (pt)
BR (1) BR112021023216A2 (pt)
CA (1) CA3138163A1 (pt)
MX (1) MX2021014576A (pt)
WO (1) WO2020243142A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024114709A1 (en) * 2022-12-01 2024-06-06 Janssen Sciences Ireland Unlimited Company A crystal form of a fused heterocycle derivative compound

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2993174A1 (en) * 2014-09-08 2016-03-09 Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt GmbH Pyrazolopyridine derivatives and their use in therapy
US9550779B2 (en) * 2014-12-30 2017-01-24 Novira Therapeutics, Inc. Derivatives and methods of treating hepatitis B infections
US10975077B2 (en) * 2016-06-29 2021-04-13 Novira Therapeutics, Inc. Diazepinone derivatives and their use in the treatment of hepatitis B infections
CN109843892B (zh) * 2016-06-29 2022-01-25 诺维拉治疗公司 噁二氮杂卓酮衍生物及其在治疗乙型肝炎感染中的用途

Also Published As

Publication number Publication date
KR20220012321A (ko) 2022-02-03
JP2022535208A (ja) 2022-08-05
CN113939512A (zh) 2022-01-14
MX2021014576A (es) 2022-01-11
WO2020243142A1 (en) 2020-12-03
EP3976616A1 (en) 2022-04-06
AU2020285719A1 (en) 2022-02-03
CA3138163A1 (en) 2020-12-03
US20220323455A1 (en) 2022-10-13

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]