BR112021022789A2 - Métodos, sistemas e dispositivos para a seleção de pacientes para tl1a - Google Patents
Métodos, sistemas e dispositivos para a seleção de pacientes para tl1aInfo
- Publication number
- BR112021022789A2 BR112021022789A2 BR112021022789A BR112021022789A BR112021022789A2 BR 112021022789 A2 BR112021022789 A2 BR 112021022789A2 BR 112021022789 A BR112021022789 A BR 112021022789A BR 112021022789 A BR112021022789 A BR 112021022789A BR 112021022789 A2 BR112021022789 A2 BR 112021022789A2
- Authority
- BR
- Brazil
- Prior art keywords
- tl1a
- systems
- methods
- devices
- selecting patients
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/241—Tumor Necrosis Factors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2875—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962847798P | 2019-05-14 | 2019-05-14 | |
| PCT/US2020/032679 WO2020232125A1 (en) | 2019-05-14 | 2020-05-13 | Tl1a patient selection methods, systems, and devices |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112021022789A2 true BR112021022789A2 (pt) | 2022-04-19 |
Family
ID=73228513
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112021022789A BR112021022789A2 (pt) | 2019-05-14 | 2020-05-13 | Métodos, sistemas e dispositivos para a seleção de pacientes para tl1a |
Country Status (12)
| Country | Link |
|---|---|
| US (5) | US20200362025A1 (https=) |
| EP (1) | EP3969621A4 (https=) |
| JP (2) | JP2022533956A (https=) |
| KR (1) | KR20220088529A (https=) |
| CN (1) | CN114375339A (https=) |
| AU (1) | AU2020275413A1 (https=) |
| BR (1) | BR112021022789A2 (https=) |
| CA (1) | CA3140029A1 (https=) |
| IL (1) | IL288017A (https=) |
| MX (1) | MX2021013974A (https=) |
| TW (1) | TW202108614A (https=) |
| WO (1) | WO2020232125A1 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2014003689A (es) | 2011-09-30 | 2014-12-05 | Teva Pharmaceuticals Australia Pty Ltd | Anticuerpos contra tl1a y sus usos. |
| KR102343212B1 (ko) | 2013-03-27 | 2021-12-23 | 세다르스-신나이 메디칼 센터 | Tl1a 기능 및 관련된 신호전달 경로의 저해에 의한 섬유증 및 염증의 완화 및 반전 |
| TWI703158B (zh) | 2015-09-18 | 2020-09-01 | 美商希佛隆公司 | 特異性結合tl1a之抗體 |
| US11186872B2 (en) | 2016-03-17 | 2021-11-30 | Cedars-Sinai Medical Center | Methods of diagnosing inflammatory bowel disease through RNASET2 |
| WO2020112890A1 (en) | 2018-11-29 | 2020-06-04 | Cedars-Sinai Medical Center | Rnaset2 compositions and methods of treatment therewith |
| TWI845600B (zh) | 2019-01-24 | 2024-06-21 | 美商普羅米修斯生物科學股份有限公司 | Gpr35調節劑 |
| JP2022533956A (ja) | 2019-05-14 | 2022-07-27 | プロメテウス バイオサイエンシーズ,インク. | Tl1a患者を選択する方法、システム、およびデバイス |
| CA3197828A1 (en) * | 2020-11-13 | 2022-05-19 | Laurens Kruidenier | Methods, systems, and kits for treatment of inflammatory diseases targeting tl1a |
| EP4263585A4 (en) * | 2020-12-21 | 2024-11-27 | Cedars-Sinai Medical Center | THERAPEUTIC COMPOSITIONS OF TL1A AND METHODS OF TREATMENT USING THEM |
| CA3207818A1 (en) * | 2021-02-18 | 2022-08-25 | Allison LUO | Anti-tl1a antibody compositions and methods of treatment in the lung |
| WO2022232253A1 (en) * | 2021-04-28 | 2022-11-03 | Cedars-Sinai Medical Center | Patient selection methods and kits for therapies targeting tl1a |
| CA3262839A1 (en) * | 2022-07-27 | 2024-02-01 | Cephalon Llc | ANTI-TL1A ANTIBODIES FOR THE TREATMENT OF ULCERATIVE COLITIS AND CROHN'S DISEASE |
| EP4637819A1 (en) * | 2022-12-22 | 2025-10-29 | Prometheus Biosciences, Inc. | Methods of treating inflammatory diseases with combination of tl1a inhibitors and s1pr inhibitors |
| EP4665395A1 (en) * | 2023-02-17 | 2025-12-24 | Prometheus Biosciences, Inc. | Anti-tl1a antibody compositions and methods of treatment in the liver |
| KR20260013470A (ko) * | 2023-05-17 | 2026-01-28 | 제넨테크, 인크. | 항-tl1a 항체 치료 방법 |
| EP4719473A1 (en) * | 2023-05-26 | 2026-04-08 | Prometheus Biosciences, Inc. | Methods, systems, and kits for treatment of inflammatory diseases by targeting tl1a |
| CN121794295A (zh) * | 2023-06-21 | 2026-04-03 | 派拉冈医疗公司 | Tl1a抗体组合物及使用方法 |
| CN121843714A (zh) | 2023-08-11 | 2026-04-10 | 派拉冈医疗公司 | Tl1a结合抗体及使用方法 |
| US12473370B2 (en) | 2023-10-03 | 2025-11-18 | Absci Corporation | TL1A associated antibody compositions and methods of use |
| US20250376530A1 (en) | 2024-05-17 | 2025-12-11 | Genentech, Inc. | Methods for treatment of inflammatory bowel disease with an anti-tl1a antibody |
| WO2026072983A1 (en) | 2024-09-27 | 2026-04-02 | Genentech, Inc. | Methods for treatment of atopic dermatitis with an anti-tl1a antibody |
| WO2026072993A1 (en) | 2024-09-27 | 2026-04-02 | Genentech, Inc. | Methods for treatment of metabolic dysfunction-associated steatohepatitis with an anti-tl1a antibody |
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| US20230272061A1 (en) | 2023-08-31 |
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| AU2020275413A1 (en) | 2021-12-23 |
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| CA3140029A1 (en) | 2020-11-19 |
| CN114375339A (zh) | 2022-04-19 |
| US11136386B2 (en) | 2021-10-05 |
| US20200362025A1 (en) | 2020-11-19 |
| MX2021013974A (es) | 2022-02-10 |
| EP3969621A1 (en) | 2022-03-23 |
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