BR112021019774A2 - Insertos oculares poliméricos dissolvíveis e método para usar os mesmos - Google Patents

Insertos oculares poliméricos dissolvíveis e método para usar os mesmos

Info

Publication number
BR112021019774A2
BR112021019774A2 BR112021019774A BR112021019774A BR112021019774A2 BR 112021019774 A2 BR112021019774 A2 BR 112021019774A2 BR 112021019774 A BR112021019774 A BR 112021019774A BR 112021019774 A BR112021019774 A BR 112021019774A BR 112021019774 A2 BR112021019774 A2 BR 112021019774A2
Authority
BR
Brazil
Prior art keywords
inserts
eye
polymeric
dissolvable
same
Prior art date
Application number
BR112021019774A
Other languages
English (en)
Portuguese (pt)
Inventor
Allen Ketelson Howard
Rekha Rangarajan
John Collins Stephen
R Laredo Walter
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Inc filed Critical Alcon Inc
Publication of BR112021019774A2 publication Critical patent/BR112021019774A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • A61K9/0051Ocular inserts or implants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BR112021019774A 2019-05-02 2020-05-01 Insertos oculares poliméricos dissolvíveis e método para usar os mesmos BR112021019774A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962841901P 2019-05-02 2019-05-02
US201962927885P 2019-10-30 2019-10-30
PCT/IB2020/054148 WO2020222195A1 (en) 2019-05-02 2020-05-01 Dissolvable polymeric eye inserts and method of using same

Publications (1)

Publication Number Publication Date
BR112021019774A2 true BR112021019774A2 (pt) 2021-12-07

Family

ID=70554143

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112021019774A BR112021019774A2 (pt) 2019-05-02 2020-05-01 Insertos oculares poliméricos dissolvíveis e método para usar os mesmos

Country Status (12)

Country Link
US (1) US12102559B2 (https=)
EP (1) EP3962450A1 (https=)
JP (1) JP7350885B2 (https=)
KR (1) KR20220004969A (https=)
CN (1) CN113795242A (https=)
AU (1) AU2020266339B2 (https=)
BR (1) BR112021019774A2 (https=)
CA (1) CA3137417C (https=)
MX (1) MX2021013428A (https=)
SG (1) SG11202110514RA (https=)
TW (1) TWI826685B (https=)
WO (1) WO2020222195A1 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11458041B2 (en) 2015-10-08 2022-10-04 Ocular Therapeutix, Inc. Punctal plug and bioadhesives
US12491263B2 (en) 2019-05-13 2025-12-09 University of Pittsburgh—of the Commonwealth System of Higher Education Polymer-based implant for retinal therapy and methods of making and using the same
PT3861985T (pt) 2020-02-06 2023-08-03 Ocular Therapeutix Inc Composições e métodos para tratar doenças oculares
EP4142664A4 (en) 2020-04-27 2024-05-29 Ocular Therapeutix, Inc. METHODS FOR TREATING ALLERGIC CONJUNCTIVITIS
US20250017769A1 (en) * 2021-11-16 2025-01-16 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Polymer-based gel implant for retinal therapy and methods of making and using the same
TW202339703A (zh) 2021-12-23 2023-10-16 瑞士商愛爾康公司 用於藥物遞送的可溶解醫療裝置
TW202341919A (zh) * 2021-12-23 2023-11-01 瑞士商愛爾康公司 用於角膜表面保護之可溶解醫療裝置及套件
TW202339704A (zh) * 2021-12-23 2023-10-16 瑞士商愛爾康公司 用於促進傷口癒合的可溶解醫療裝置
WO2023214027A1 (en) * 2022-05-06 2023-11-09 Eyed Pharma Insert for the treatment of dry eyes
US20240207174A1 (en) * 2022-12-23 2024-06-27 Alcon Inc. Dissolvable polymeric eye inserts
WO2024180472A1 (en) * 2023-02-28 2024-09-06 Alcon Inc. Ocular inserts
WO2024180453A1 (en) * 2023-02-28 2024-09-06 Alcon Inc. Dissolvable polymeric eye inserts with a non-ionic cellulose derivative

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4730013A (en) * 1981-10-08 1988-03-08 Merck & Co., Inc. Biosoluble ocular insert
PT75625B (en) * 1981-10-08 1985-12-09 Merck & Co Inc Process for preparing biosoluble ocular insert
AU6107696A (en) 1995-06-07 1996-12-30 Keravision, Inc. Radial intrastromal corneal insert and a method of insertion
AU2006227116A1 (en) 2005-03-21 2006-09-28 Santen Pharmaceutical Co., Ltd. Drug delivery systems for treatment of diseases or conditions
AU2006330915B2 (en) 2005-12-23 2011-02-03 Intercontinental Great Brands Llc Compositions providing a sensation substantially similar to that provided by menthol
ZA200904917B (en) 2007-02-09 2010-09-29 Alcon Inc Ophthalmic compositions containing a synergistic combination of three polymers
US20130244978A1 (en) * 2007-09-14 2013-09-19 Rohto Pharmaceutical Co., Ltd. Ophthalmic composition
US20130172357A1 (en) 2011-02-03 2013-07-04 Eye Therapies Llc Compositions and Methods for Treatment of Glaucoma
US20120215184A1 (en) 2011-02-18 2012-08-23 Valeant International (Barbados) Srl Cylindrical ocular inserts
US20140107025A1 (en) 2012-04-16 2014-04-17 Jade Therapeutics, Llc Ocular drug delivery system
UA113434C2 (uk) * 2012-05-04 2017-01-25 Алкон Рісерч, Лтд. Офтальмологічна композиція з поліпшеним захистом від зневоднювання й утриманням
RU2683651C2 (ru) 2013-06-18 2019-04-01 Иван Дмитриевич Захаров Лекарственное средство для лечения кератоконуса и других дегенеративных заболеваний роговицы и фармацевтические препараты на его основе
US9782345B2 (en) 2013-10-17 2017-10-10 Jade Therapeutics, Inc. Ocular composition and method
CA2947274C (en) * 2014-04-28 2019-03-19 Hampton Technologies Ophthalmic compositions and methods for treating eyes
GB2541840B (en) 2014-06-20 2017-09-06 Coopervision Int Holding Co Lp Ophthalmic composition for the treatment of ocular infection
US9931306B2 (en) 2014-09-06 2018-04-03 Integral Biosystems Llc Methods and biocompatible compositions to achieve sustained drug release in the eye

Also Published As

Publication number Publication date
SG11202110514RA (en) 2021-11-29
MX2021013428A (es) 2021-12-10
WO2020222195A1 (en) 2020-11-05
KR20220004969A (ko) 2022-01-12
US12102559B2 (en) 2024-10-01
JP7350885B2 (ja) 2023-09-26
CA3137417C (en) 2024-01-09
TW202106286A (zh) 2021-02-16
EP3962450A1 (en) 2022-03-09
JP2022530758A (ja) 2022-07-01
TWI826685B (zh) 2023-12-21
CA3137417A1 (en) 2020-11-05
AU2020266339A1 (en) 2021-12-23
AU2020266339B2 (en) 2023-12-07
CN113795242A (zh) 2021-12-14
US20200345544A1 (en) 2020-11-05

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Legal Events

Date Code Title Description
B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements
B11N Dismissal: publication cancelled [chapter 11.14 patent gazette]

Free format text: ANULADA A PUBLICACAO CODIGO 11.2 NA RPI NO 2824 DE 18/02/2025 POR TER SIDO INDEVIDA.