MX2021013428A - Insertos oculares polimericos disolubles y metodo de uso de los mismos. - Google Patents

Insertos oculares polimericos disolubles y metodo de uso de los mismos.

Info

Publication number
MX2021013428A
MX2021013428A MX2021013428A MX2021013428A MX2021013428A MX 2021013428 A MX2021013428 A MX 2021013428A MX 2021013428 A MX2021013428 A MX 2021013428A MX 2021013428 A MX2021013428 A MX 2021013428A MX 2021013428 A MX2021013428 A MX 2021013428A
Authority
MX
Mexico
Prior art keywords
inserts
eye
same
ocular surface
eye inserts
Prior art date
Application number
MX2021013428A
Other languages
English (en)
Inventor
Walter R Laredo
Rekha Rangarajan
Howard Allen Ketelson
Stephen John Collins
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Inc filed Critical Alcon Inc
Publication of MX2021013428A publication Critical patent/MX2021013428A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof

Abstract

Se proporcionan insertos oculares poliméricos que pueden ser disolubles cuando se colocan en el fondo de saco del ojo. Estos insertos pueden contener uno o más polímeros, así como un reblandecedor/plastificante, de modo que, cuando se inserten en el ojo, estos puedan absorber las lágrimas y disolver y liberar lentamente el lubricante en la película lagrimal para lubricar y proteger la superficie ocular durante un período de tiempo prolongado. Un tiempo de retención aumentado sobre la superficie ocular para un alivio más duradero puede reducir la frecuencia de dosificación y la carga para el paciente típicamente asociada al uso de gotas tópicas. Estos insertos oculares poliméricos también pueden incluir uno o más agentes farmacéuticamente activos.
MX2021013428A 2019-05-02 2020-05-01 Insertos oculares polimericos disolubles y metodo de uso de los mismos. MX2021013428A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962841901P 2019-05-02 2019-05-02
US201962927885P 2019-10-30 2019-10-30
PCT/IB2020/054148 WO2020222195A1 (en) 2019-05-02 2020-05-01 Dissolvable polymeric eye inserts and method of using same

Publications (1)

Publication Number Publication Date
MX2021013428A true MX2021013428A (es) 2021-12-10

Family

ID=70554143

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2021013428A MX2021013428A (es) 2019-05-02 2020-05-01 Insertos oculares polimericos disolubles y metodo de uso de los mismos.

Country Status (11)

Country Link
US (1) US20200345544A1 (es)
EP (1) EP3962450A1 (es)
JP (1) JP7350885B2 (es)
KR (1) KR20220004969A (es)
CN (1) CN113795242A (es)
AU (1) AU2020266339B2 (es)
CA (1) CA3137417C (es)
MX (1) MX2021013428A (es)
SG (1) SG11202110514RA (es)
TW (1) TWI826685B (es)
WO (1) WO2020222195A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11458041B2 (en) 2015-10-08 2022-10-04 Ocular Therapeutix, Inc. Punctal plug and bioadhesives
FI3861985T3 (fi) 2020-02-06 2023-08-07 Ocular Therapeutix Inc Koostumuksia ja menetelmiä silmätautien hoitamiseksi
US20230201030A1 (en) * 2021-12-23 2023-06-29 Alcon Inc. Dissolvable medical device for drugs delivery
WO2023119231A1 (en) * 2021-12-23 2023-06-29 Alcon Inc. Dissolvable medical device and kit for corneal surface protection
US20230201031A1 (en) * 2021-12-23 2023-06-29 Alcon Inc. Dissolvable medical device for promoting healing of wounds
WO2023214027A1 (en) * 2022-05-06 2023-11-09 Eyed Pharma Insert for the treatment of dry eyes

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT75625B (en) * 1981-10-08 1985-12-09 Merck & Co Inc Process for preparing biosoluble ocular insert
US4730013A (en) * 1981-10-08 1988-03-08 Merck & Co., Inc. Biosoluble ocular insert
KR20070121754A (ko) * 2005-03-21 2007-12-27 마커사이트, 인코포레이티드 질환 또는 상태의 치료를 위한 약물 송달 시스템
BRPI0620328A2 (pt) * 2005-12-23 2011-11-08 Cadbury Adams Usa Llc composições que proporcionam uma sensação substancialmente similar à proporcionada pelo mentol
ZA200904917B (en) * 2007-02-09 2010-09-29 Alcon Inc Ophthalmic compositions containing a synergistic combination of three polymers
US20130244978A1 (en) * 2007-09-14 2013-09-19 Rohto Pharmaceutical Co., Ltd. Ophthalmic composition
US20130172357A1 (en) * 2011-02-03 2013-07-04 Eye Therapies Llc Compositions and Methods for Treatment of Glaucoma
CA2947274C (en) * 2014-04-28 2019-03-19 Hampton Technologies Ophthalmic compositions and methods for treating eyes

Also Published As

Publication number Publication date
SG11202110514RA (en) 2021-11-29
AU2020266339B2 (en) 2023-12-07
AU2020266339A1 (en) 2021-12-23
EP3962450A1 (en) 2022-03-09
CA3137417C (en) 2024-01-09
TW202106286A (zh) 2021-02-16
JP2022530758A (ja) 2022-07-01
TWI826685B (zh) 2023-12-21
JP7350885B2 (ja) 2023-09-26
CN113795242A (zh) 2021-12-14
US20200345544A1 (en) 2020-11-05
CA3137417A1 (en) 2020-11-05
KR20220004969A (ko) 2022-01-12
WO2020222195A1 (en) 2020-11-05

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