BR112021016595A2 - Método de diagnóstico ou prognóstico de câncer, métodos para diagnosticar câncer ou para triagem de câncer, para monitorar um indivíduo, para monitorar o tratamento de câncer, para avaliar a resposta de um indivíduo a um tratamento de câncer e para tratar um indivíduo com câncer detectado, kit e uso do kit - Google Patents

Método de diagnóstico ou prognóstico de câncer, métodos para diagnosticar câncer ou para triagem de câncer, para monitorar um indivíduo, para monitorar o tratamento de câncer, para avaliar a resposta de um indivíduo a um tratamento de câncer e para tratar um indivíduo com câncer detectado, kit e uso do kit

Info

Publication number
BR112021016595A2
BR112021016595A2 BR112021016595A BR112021016595A BR112021016595A2 BR 112021016595 A2 BR112021016595 A2 BR 112021016595A2 BR 112021016595 A BR112021016595 A BR 112021016595A BR 112021016595 A BR112021016595 A BR 112021016595A BR 112021016595 A2 BR112021016595 A2 BR 112021016595A2
Authority
BR
Brazil
Prior art keywords
cancer
individual
diagnosing
monitoring
kit
Prior art date
Application number
BR112021016595A
Other languages
English (en)
Inventor
Aoife Gahlawat
Christof Sohn
Sarah Schott
Witte Tobar Tania
Original Assignee
Univ Heidelberg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Heidelberg filed Critical Univ Heidelberg
Publication of BR112021016595A2 publication Critical patent/BR112021016595A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

método de diagnóstico ou prognóstico de câncer, métodos para diagnosticar câncer ou para triagem de câncer, para monitorar um indivíduo, para monitorar o tratamento de câncer, para avaliar a resposta de um indivíduo a um tratamento de câncer e para tratar um indivíduo com câncer detectado, kit e uso do kit. a presente invenção se refere a um método de diagnóstico ou prognóstico de câncer compreendendo a determinação dos níveis de metilação de citosina in vitro dentro de genes marcadores e/ou a determinação dos níveis de expressão de marcadores de mirna.
BR112021016595A 2019-02-21 2020-02-21 Método de diagnóstico ou prognóstico de câncer, métodos para diagnosticar câncer ou para triagem de câncer, para monitorar um indivíduo, para monitorar o tratamento de câncer, para avaliar a resposta de um indivíduo a um tratamento de câncer e para tratar um indivíduo com câncer detectado, kit e uso do kit BR112021016595A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19158682 2019-02-21
EP19174483 2019-05-14
PCT/EP2020/054667 WO2020169826A1 (en) 2019-02-21 2020-02-21 Biomarker panel for diagnosis and prognosis of cancer

Publications (1)

Publication Number Publication Date
BR112021016595A2 true BR112021016595A2 (pt) 2021-11-03

Family

ID=69630329

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112021016595A BR112021016595A2 (pt) 2019-02-21 2020-02-21 Método de diagnóstico ou prognóstico de câncer, métodos para diagnosticar câncer ou para triagem de câncer, para monitorar um indivíduo, para monitorar o tratamento de câncer, para avaliar a resposta de um indivíduo a um tratamento de câncer e para tratar um indivíduo com câncer detectado, kit e uso do kit

Country Status (10)

Country Link
US (1) US20220127678A1 (pt)
EP (1) EP3927849A1 (pt)
JP (1) JP2022523366A (pt)
KR (1) KR20210132033A (pt)
AU (1) AU2020223871A1 (pt)
BR (1) BR112021016595A2 (pt)
CA (1) CA3127154A1 (pt)
IL (1) IL284827A (pt)
MX (1) MX2021010086A (pt)
WO (1) WO2020169826A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112195246B (zh) * 2020-10-19 2022-08-09 中国人民解放军空军军医大学 一种肝细胞肝癌标志物及检测试剂盒
CN113061648B (zh) * 2021-03-24 2022-04-19 中山大学 一种采用Tn5转座酶辅助构建微量样品m6A修饰检测文库的方法及其应用
DE102021126650A1 (de) * 2021-10-14 2023-04-20 Rheinische Friedrich-Wilhelms-Universität Bonn, Körperschaft des öffentlichen Rechts Verfahren zur bestimmung der ansprechwahrscheinlichkeit einer malignen erkrankung auf eine behandlung mit einem pharmazeutischen hemmwirkstoff

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3409794B1 (en) * 2014-05-02 2021-03-24 Ruprecht-Karls-Universität Heidelberg Circulating mirnas as early detection marker and prognostic marker
EP3262190B1 (en) * 2015-02-24 2021-09-01 Ruprecht-Karls-Universität Heidelberg Biomarker panel for the detection of cancer

Also Published As

Publication number Publication date
JP2022523366A (ja) 2022-04-22
CA3127154A1 (en) 2020-08-27
IL284827A (en) 2021-08-31
MX2021010086A (es) 2021-09-21
AU2020223871A1 (en) 2021-08-26
WO2020169826A1 (en) 2020-08-27
EP3927849A1 (en) 2021-12-29
KR20210132033A (ko) 2021-11-03
US20220127678A1 (en) 2022-04-28

Similar Documents

Publication Publication Date Title
BR112021016595A2 (pt) Método de diagnóstico ou prognóstico de câncer, métodos para diagnosticar câncer ou para triagem de câncer, para monitorar um indivíduo, para monitorar o tratamento de câncer, para avaliar a resposta de um indivíduo a um tratamento de câncer e para tratar um indivíduo com câncer detectado, kit e uso do kit
ZA202000935B (en) Methods and materials for assessing and treating cancer
Brustugun et al. BRAF-mutations in non-small cell lung cancer
BR112015023120A2 (pt) método para identificar um indivíduo com uma doença ou disfunção, método para prever a responsividade de um indivíduo com uma doença ou disfunção, método para determinar a probabilidade de que um indivíduo com uma doença ou disfunção exibirá benefício do tratamento, método para selecionar uma terapia, usos de um antagonista de ligação do eixo pd-l1, ensaio para identificar um indivíduo com uma doença, kit de diagnóstico, método para avaliar uma resposta ao tratamento e método para monitorar a resposta de um indivíduo tratado
MX2009012722A (es) Variantes geneticas sobre chr 5p12 y 10q26 como marcadores para el uso en la evaluacion del riesgo, diagnostico, pronostico y tratamiento del cancer de mama.
ES2530843T3 (es) Métodos basados en microARN para el diagnóstico de cáncer de páncreas
EP3839510A3 (en) Blood-based biomarkers of tumor sensitivity to pd-1 antagonists
PH12018550037A1 (en) Quencher containing water-soluble polymer-conjugated nanomaterial and use thereof
BR112018013430A2 (pt) ?métodos para detectar pelo menos uma mutação em uma pluralidade de genes relacionados a câncer de tireoide, para selecionar um sujeito que tem nódulos na tireoide e para prognosticar risco de malignidade, e, kit?
BR112014018331A8 (pt) Biomarcadores e terapias combinadas usando vírus oncolítico e imunomodulação
MX2017015210A (es) Composiciones y metodos para el cribado de tumores solidos.
RU2014110228A (ru) Диагностические маркеры
Minami et al. SS 18‐SSX‐regulated miR‐17 promotes tumor growth of synovial sarcoma by inhibiting p21 WAF 1/CIP 1
BR112016007864A2 (pt) método para a prognose e tratamento de metástase de câncer
Stark et al. Expression of DNA mismatch repair proteins MLH1, MSH2, and MSH6 in recurrent glioblastoma
AR099856A1 (es) Métodos para diagnosticar y tratar la enfermedad de intestino inflamado
ATE554389T1 (de) Apex als marker für lungenkrebs
BR112013000869A2 (pt) método para diagnóstico de câncer de próstata (pca) com uma sensibilidade desejada em um sujeito; método para monitorar a progressão do câncer de próstata (pca) em um sujeito; método para avaliar se um sujeito tem que ser submetido a uma biópsia de próstata; kit compreendendo um primeiro componente e, opcionalmente, um segundo componente e uso de um kit
WO2008037700A3 (en) Methods for breast cancer prognosis
NZ589251A (en) Novel marker for detection of bladder cancer
MXPA06014175A (es) Diagnostico o pronostico del curso del cancer de mama.
PL405648A1 (pl) Sposób diagnozowania raka watrobowokomórkowego, zastosowanie markera mikroRNA do diagnozowania zmiany chorobowej w obrębie wątroby, oceny stopnia zaawansowania choroby oraz oceny podatności pacjenta i/lub choroby na zaproponowane leczenie oraz zawierający takie markery zestaw diagnostyczny
WO2007146668A3 (en) Use of imp3 as a prognostic marker for cancer
BR112021023731A2 (pt) Método para calcular a idade biológica de um sujeito; combinação de biomarcadores de metilação de dna para calcular a idade biológica, kit para determinar a idade biológica de um sujeito, método implementado por computador para fornecer recomendações para mudanças no estilo de vida, e método para desenvolver uma mídia legível por computador
BR112015012507A8 (pt) método in vitro de seleção de um indivíduo diagnosticado ou suspeito de ter câncer e uso de um inibidor de telomerase