BR112019019301A2 - compostos anticâncer - Google Patents

compostos anticâncer Download PDF

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Publication number
BR112019019301A2
BR112019019301A2 BR112019019301-4A BR112019019301A BR112019019301A2 BR 112019019301 A2 BR112019019301 A2 BR 112019019301A2 BR 112019019301 A BR112019019301 A BR 112019019301A BR 112019019301 A2 BR112019019301 A2 BR 112019019301A2
Authority
BR
Brazil
Prior art keywords
substituted
unsubstituted
fact
compound
hydrogen
Prior art date
Application number
BR112019019301-4A
Other languages
English (en)
Portuguese (pt)
Inventor
María Cañedo Hernández Librada
De La Calle Verdú Fernando
Pilar Rodríguez Ramos María
Del Carmen Schleissner Sánchez María
Zúñiga Girón Paz
Original Assignee
Pharma Mar, S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharma Mar, S.A. filed Critical Pharma Mar, S.A.
Publication of BR112019019301A2 publication Critical patent/BR112019019301A2/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/07—Bacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185—Escherichia
    • C12R2001/19—Escherichia coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/38—Pseudomonas
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
BR112019019301-4A 2017-03-17 2018-03-16 compostos anticâncer BR112019019301A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17382140.6 2017-03-17
EP17382140 2017-03-17
PCT/EP2018/056665 WO2018167270A1 (en) 2017-03-17 2018-03-16 Anticancer compounds

Publications (1)

Publication Number Publication Date
BR112019019301A2 true BR112019019301A2 (pt) 2020-04-28

Family

ID=58398130

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112019019301-4A BR112019019301A2 (pt) 2017-03-17 2018-03-16 compostos anticâncer

Country Status (17)

Country Link
US (1) US20210317490A1 (https=)
EP (1) EP3596068A1 (https=)
JP (1) JP7209633B2 (https=)
KR (1) KR102547649B1 (https=)
CN (1) CN110650954B (https=)
AU (2) AU2018235140B2 (https=)
BR (1) BR112019019301A2 (https=)
CA (1) CA3056725A1 (https=)
CL (2) CL2019002661A1 (https=)
IL (2) IL292572A (https=)
MA (1) MA49880A (https=)
MX (2) MX392144B (https=)
MY (2) MY202630A (https=)
SG (1) SG11201908267XA (https=)
UA (1) UA126338C2 (https=)
WO (1) WO2018167270A1 (https=)
ZA (2) ZA201906518B (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12156523B2 (en) 2017-03-17 2024-12-03 Mmag Co., Ltd. Plant disease control agent
CN114615999B (zh) * 2019-09-05 2024-03-08 法马马有限公司 药物抗体偶联物
CN112661808B (zh) * 2020-12-23 2022-05-27 浙江大学 一种酯肽类化合物及其制备方法和应用
EP4326869A4 (en) * 2021-04-20 2025-12-10 Univ Of Louisville RECOMBINATING MICRO-NECK

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2040338T3 (es) 1987-04-29 1993-10-16 Harbor Branch Oceanographic Institution, Inc. Compuestos antitumorales y antiviricos de origen marino.
US4801606A (en) 1987-07-17 1989-01-31 Harbor Branch Oceanographic Institution Inc. Antiviral compositions
EP1448767B1 (en) 2001-11-22 2010-10-13 Rheinische Friedrich-Wilhelms-Universität Bonn Novel gene cluster of pederin biosynthesis genes
WO2013016120A1 (en) 2011-07-22 2013-01-31 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Pederin and psymberin agents

Also Published As

Publication number Publication date
KR20190129950A (ko) 2019-11-20
MX2019010890A (es) 2019-12-19
IL269353B (en) 2022-06-01
AU2018235140B2 (en) 2021-11-11
CL2019002661A1 (es) 2019-12-27
JP2020510065A (ja) 2020-04-02
CA3056725A1 (en) 2018-09-20
CN110650954B (zh) 2023-11-03
IL269353A (en) 2019-11-28
WO2018167270A1 (en) 2018-09-20
RU2019132808A3 (https=) 2021-10-04
AU2021277683A1 (en) 2021-12-23
JP7209633B2 (ja) 2023-01-20
IL292572A (en) 2022-06-01
CN110650954A (zh) 2020-01-03
US20210317490A1 (en) 2021-10-14
AU2018235140A1 (en) 2019-10-03
AU2021277683B2 (en) 2023-03-09
MX2021011385A (es) 2021-10-13
MX392144B (es) 2025-03-21
CL2021000117A1 (es) 2021-07-30
MA49880A (fr) 2020-06-24
MY202630A (en) 2024-05-10
EP3596068A1 (en) 2020-01-22
KR102547649B1 (ko) 2023-06-23
UA126338C2 (uk) 2022-09-21
MY195435A (en) 2023-01-20
RU2019132808A (ru) 2021-04-19
ZA201906518B (en) 2021-01-27
SG11201908267XA (en) 2019-10-30
ZA202006147B (en) 2023-03-29

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Legal Events

Date Code Title Description
B350 Update of information on the portal [chapter 15.35 patent gazette]
B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE.