AU2018235140B2 - Anticancer compounds - Google Patents

Anticancer compounds Download PDF

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Publication number
AU2018235140B2
AU2018235140B2 AU2018235140A AU2018235140A AU2018235140B2 AU 2018235140 B2 AU2018235140 B2 AU 2018235140B2 AU 2018235140 A AU2018235140 A AU 2018235140A AU 2018235140 A AU2018235140 A AU 2018235140A AU 2018235140 B2 AU2018235140 B2 AU 2018235140B2
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AU
Australia
Prior art keywords
ala
leu
gly
ser
asp
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2018235140A
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English (en)
Other versions
AU2018235140A1 (en
Inventor
Librada María CAÑEDO HERNÁNDEZ
Fernando DE LA CALLE VERDÚ
María Pilar RODRÍGUEZ RAMOS
María del Carmen SCHLEISSNER SÁNCHEZ
Paz ZÚÑIGA GIRÓN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmamar SA
Original Assignee
Pharmamar SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmamar SA filed Critical Pharmamar SA
Publication of AU2018235140A1 publication Critical patent/AU2018235140A1/en
Application granted granted Critical
Publication of AU2018235140B2 publication Critical patent/AU2018235140B2/en
Priority to AU2021277683A priority Critical patent/AU2021277683B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/07—Bacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185—Escherichia
    • C12R2001/19—Escherichia coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/38—Pseudomonas
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU2018235140A 2017-03-17 2018-03-16 Anticancer compounds Ceased AU2018235140B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2021277683A AU2021277683B2 (en) 2017-03-17 2021-12-01 Anticancer Compounds

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17382140.6 2017-03-17
EP17382140 2017-03-17
PCT/EP2018/056665 WO2018167270A1 (en) 2017-03-17 2018-03-16 Anticancer compounds

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2021277683A Division AU2021277683B2 (en) 2017-03-17 2021-12-01 Anticancer Compounds

Publications (2)

Publication Number Publication Date
AU2018235140A1 AU2018235140A1 (en) 2019-10-03
AU2018235140B2 true AU2018235140B2 (en) 2021-11-11

Family

ID=58398130

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2018235140A Ceased AU2018235140B2 (en) 2017-03-17 2018-03-16 Anticancer compounds
AU2021277683A Ceased AU2021277683B2 (en) 2017-03-17 2021-12-01 Anticancer Compounds

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2021277683A Ceased AU2021277683B2 (en) 2017-03-17 2021-12-01 Anticancer Compounds

Country Status (17)

Country Link
US (1) US20210317490A1 (https=)
EP (1) EP3596068A1 (https=)
JP (1) JP7209633B2 (https=)
KR (1) KR102547649B1 (https=)
CN (1) CN110650954B (https=)
AU (2) AU2018235140B2 (https=)
BR (1) BR112019019301A2 (https=)
CA (1) CA3056725A1 (https=)
CL (2) CL2019002661A1 (https=)
IL (2) IL292572A (https=)
MA (1) MA49880A (https=)
MX (2) MX392144B (https=)
MY (2) MY202630A (https=)
SG (1) SG11201908267XA (https=)
UA (1) UA126338C2 (https=)
WO (1) WO2018167270A1 (https=)
ZA (2) ZA201906518B (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12156523B2 (en) 2017-03-17 2024-12-03 Mmag Co., Ltd. Plant disease control agent
CN114615999B (zh) * 2019-09-05 2024-03-08 法马马有限公司 药物抗体偶联物
CN112661808B (zh) * 2020-12-23 2022-05-27 浙江大学 一种酯肽类化合物及其制备方法和应用
EP4326869A4 (en) * 2021-04-20 2025-12-10 Univ Of Louisville RECOMBINATING MICRO-NECK

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2040338T3 (es) 1987-04-29 1993-10-16 Harbor Branch Oceanographic Institution, Inc. Compuestos antitumorales y antiviricos de origen marino.
US4801606A (en) 1987-07-17 1989-01-31 Harbor Branch Oceanographic Institution Inc. Antiviral compositions
EP1448767B1 (en) 2001-11-22 2010-10-13 Rheinische Friedrich-Wilhelms-Universität Bonn Novel gene cluster of pederin biosynthesis genes
WO2013016120A1 (en) 2011-07-22 2013-01-31 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Pederin and psymberin agents

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NARQUIZIAN R ET AL, "The pederin family of antitumor agents: structures, synthesis and biological activity", 2000-01-01, no. 32, pages 25 - 56 *

Also Published As

Publication number Publication date
KR20190129950A (ko) 2019-11-20
MX2019010890A (es) 2019-12-19
IL269353B (en) 2022-06-01
CL2019002661A1 (es) 2019-12-27
JP2020510065A (ja) 2020-04-02
CA3056725A1 (en) 2018-09-20
CN110650954B (zh) 2023-11-03
IL269353A (en) 2019-11-28
WO2018167270A1 (en) 2018-09-20
RU2019132808A3 (https=) 2021-10-04
AU2021277683A1 (en) 2021-12-23
JP7209633B2 (ja) 2023-01-20
IL292572A (en) 2022-06-01
CN110650954A (zh) 2020-01-03
US20210317490A1 (en) 2021-10-14
AU2018235140A1 (en) 2019-10-03
AU2021277683B2 (en) 2023-03-09
MX2021011385A (es) 2021-10-13
MX392144B (es) 2025-03-21
CL2021000117A1 (es) 2021-07-30
MA49880A (fr) 2020-06-24
MY202630A (en) 2024-05-10
EP3596068A1 (en) 2020-01-22
KR102547649B1 (ko) 2023-06-23
UA126338C2 (uk) 2022-09-21
MY195435A (en) 2023-01-20
RU2019132808A (ru) 2021-04-19
ZA201906518B (en) 2021-01-27
SG11201908267XA (en) 2019-10-30
BR112019019301A2 (pt) 2020-04-28
ZA202006147B (en) 2023-03-29

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FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired