BR112019017017A2 - método de tratamento de um indivíduo humano que tem câncer, anticorpo anti-cd25, uso de um anticorpo anti-cd25, combinação de um anticorpo anti-cd25, kit para o uso no tratamento de câncer, composição farmacêutica, combinação, anticorpo biespecífico, método de tratamento de câncer, e método de depleção de células t regulatórias em um indivíduo - Google Patents
método de tratamento de um indivíduo humano que tem câncer, anticorpo anti-cd25, uso de um anticorpo anti-cd25, combinação de um anticorpo anti-cd25, kit para o uso no tratamento de câncer, composição farmacêutica, combinação, anticorpo biespecífico, método de tratamento de câncer, e método de depleção de células t regulatórias em um indivíduo Download PDFInfo
- Publication number
- BR112019017017A2 BR112019017017A2 BR112019017017A BR112019017017A BR112019017017A2 BR 112019017017 A2 BR112019017017 A2 BR 112019017017A2 BR 112019017017 A BR112019017017 A BR 112019017017A BR 112019017017 A BR112019017017 A BR 112019017017A BR 112019017017 A2 BR112019017017 A2 BR 112019017017A2
- Authority
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- Brazil
- Prior art keywords
- antibody
- seq
- amino acid
- cells
- acid sequence
- Prior art date
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/55—IL-2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17161717 | 2017-03-17 | ||
| GBGB1710879.6A GB201710879D0 (en) | 2017-07-06 | 2017-07-06 | Methods and compounds for tumour-specific cell depletion |
| GBGB1714429.6A GB201714429D0 (en) | 2017-09-07 | 2017-09-07 | Compounds and methods for tumour-specific cell depletion |
| PCT/EP2018/056312 WO2018167104A1 (en) | 2017-03-17 | 2018-03-13 | Fc-optimized anti-cd25 for tumour specific cell depletion |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112019017017A2 true BR112019017017A2 (pt) | 2020-04-14 |
Family
ID=61655786
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112019017017A BR112019017017A2 (pt) | 2017-03-17 | 2018-03-13 | método de tratamento de um indivíduo humano que tem câncer, anticorpo anti-cd25, uso de um anticorpo anti-cd25, combinação de um anticorpo anti-cd25, kit para o uso no tratamento de câncer, composição farmacêutica, combinação, anticorpo biespecífico, método de tratamento de câncer, e método de depleção de células t regulatórias em um indivíduo |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US11879014B2 (enExample) |
| EP (1) | EP3596123B1 (enExample) |
| JP (2) | JP2020514363A (enExample) |
| KR (1) | KR20190130137A (enExample) |
| CN (1) | CN110869388B (enExample) |
| AU (1) | AU2018233976B2 (enExample) |
| BR (1) | BR112019017017A2 (enExample) |
| CA (1) | CA3056506A1 (enExample) |
| CL (1) | CL2019002624A1 (enExample) |
| CR (1) | CR20190477A (enExample) |
| DK (1) | DK3596123T3 (enExample) |
| ES (1) | ES2975063T3 (enExample) |
| FI (1) | FI3596123T3 (enExample) |
| HR (1) | HRP20240469T1 (enExample) |
| HU (1) | HUE065999T2 (enExample) |
| IL (1) | IL269081A (enExample) |
| LT (1) | LT3596123T (enExample) |
| MX (1) | MX2019010974A (enExample) |
| MY (1) | MY208220A (enExample) |
| NZ (1) | NZ756984A (enExample) |
| PE (1) | PE20191812A1 (enExample) |
| PL (1) | PL3596123T3 (enExample) |
| RS (1) | RS65351B1 (enExample) |
| SG (1) | SG11201908578YA (enExample) |
| SI (1) | SI3596123T1 (enExample) |
| WO (1) | WO2018167104A1 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11371066B2 (en) | 2015-07-13 | 2022-06-28 | Modular Genetics, Inc. | Generation of acyl alcohols |
| US11879014B2 (en) | 2017-03-17 | 2024-01-23 | Tusk Therapeutics Ltd. | Method of treating cancer or depleting regulatory T cells in a subject by administering a human IGG1 anti-CD25 antibody |
| WO2019175222A1 (en) * | 2018-03-13 | 2019-09-19 | Tusk Therapeutics Ltd | Anti-cd25 for tumour specific cell depletion |
| WO2020102603A1 (en) * | 2018-11-14 | 2020-05-22 | Rubryc Therapeutics, Inc. | Engineered cd25 polypeptides and uses thereof |
| CN113677359A (zh) | 2018-11-14 | 2021-11-19 | 鲁比克治疗股份有限公司 | Cd25抗体 |
| US20220251232A1 (en) * | 2019-05-20 | 2022-08-11 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Novel anti-cd25 antibodies |
| WO2020248938A1 (zh) * | 2019-06-10 | 2020-12-17 | 山东博安生物技术有限公司 | 抗cd25抗体及其应用 |
| WO2021207691A1 (en) | 2020-04-10 | 2021-10-14 | Rakuten Medical, Inc. | Phthalocyanine dye compounds, conjugates and methods of use thereof |
| CN115397860B (zh) * | 2020-05-14 | 2025-06-13 | 江苏恒瑞医药股份有限公司 | 抗cd25抗体、其抗原结合片段及其医药用途 |
| US11124568B1 (en) * | 2020-08-19 | 2021-09-21 | Vitruviae LLC | CD3/CD25 antibodies for neuro-immune diseases |
| WO2022106665A1 (en) * | 2020-11-20 | 2022-05-27 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Anti-cd25 antibodies |
| WO2022106663A1 (en) * | 2020-11-20 | 2022-05-27 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Anti-cd25 antibodies |
| US20240018248A1 (en) | 2020-12-02 | 2024-01-18 | Vib Vzw | An ltbr agonist in combination therapy against cancer |
| US20240307541A1 (en) * | 2021-02-02 | 2024-09-19 | Rakuten Medical, Inc. | Methods for local and systemic treatment of cancers, tumors and tumor cells |
| CA3209636A1 (en) | 2021-03-01 | 2022-09-09 | F. Hoffmann-La Roche Ag | Novel biomarkers and uses thereof |
| JP2024533119A (ja) | 2021-09-02 | 2024-09-12 | エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト | Ａｍｌの治療のための抗体 |
| WO2023208990A1 (en) | 2022-04-26 | 2023-11-02 | F. Hoffmann-La Roche Ag | Combination therapy for the treatment of cancer comprising a fas axis antagonist and a t-reg cell depleting agent antagonist, |
| CN115181182B (zh) * | 2022-06-13 | 2024-03-29 | 南京融捷康生物科技有限公司 | 一种人源化的抗cd25的单域抗体及其应用 |
| AU2023299296A1 (en) * | 2022-06-30 | 2025-01-16 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Cd25-specific antibodies and uses thereof |
| US20250361308A1 (en) | 2022-07-01 | 2025-11-27 | Neurogene Inc. | NEO-2/15 Variants and Uses Thereof for Preferentially Stimulating T-Regulatory Cells |
| WO2024088987A1 (en) | 2022-10-26 | 2024-05-02 | F. Hoffmann-La Roche Ag | Combination therapy for the treatment of cancer |
| CN118240080A (zh) * | 2022-12-22 | 2024-06-25 | 深圳市福元生物科技有限公司 | 一种cd25单域抗体、人源化抗体、及制备方法 |
| CN120584138A (zh) | 2023-02-06 | 2025-09-02 | 豪夫迈·罗氏有限公司 | 组合疗法及其用途 |
| CN116087499B (zh) * | 2023-02-20 | 2023-10-31 | 深圳裕康医学检验实验室 | 一种癌样本的染色方法及试剂盒 |
| CN120314588B (zh) * | 2025-05-21 | 2025-10-17 | 成都蓉生药业有限责任公司 | 一种人免疫球蛋白抗体依赖性细胞介导的吞噬作用生物学活性的检测方法和检测试剂盒 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US4208479A (en) | 1977-07-14 | 1980-06-17 | Syva Company | Label modified immunoassays |
| IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
| JPH05244982A (ja) | 1991-12-06 | 1993-09-24 | Sumitomo Chem Co Ltd | 擬人化ｂ−ｂ１０ |
| NZ540555A (en) | 2002-11-15 | 2008-04-30 | Genmab As | Antibody therapeutics for treatingand/or preventing diseases associated with cells expressing CD25, including autoimmune diseases, inflammatory and hyperproliferative skin disorders |
| US20050181375A1 (en) | 2003-01-10 | 2005-08-18 | Natasha Aziz | Novel methods of diagnosis of metastatic cancer, compositions and methods of screening for modulators of metastatic cancer |
| GB0409799D0 (en) * | 2004-04-30 | 2004-06-09 | Isis Innovation | Method of generating improved immune response |
| GB0507696D0 (en) | 2005-04-15 | 2005-05-25 | Novartis Ag | Organic compounds |
| EP2032159B1 (en) | 2006-06-26 | 2015-01-07 | MacroGenics, Inc. | Combination of fcgammariib antibodies and cd20-specific antibodies and methods of use thereof |
| AU2007271398B2 (en) | 2006-07-06 | 2013-06-20 | Merck Patent Gmbh | Compositions and methods for enhancing the efficacy of IL-2 mediated immune responses |
| HRP20140081T1 (hr) | 2006-08-18 | 2014-03-28 | Novartis Ag | Prlr-specifiäśna antitijela i njihova uporaba |
| RU2391401C2 (ru) | 2008-02-12 | 2010-06-10 | Общество с ограниченной ответственностью "Лаборатория клеточного мониторинга" | СПОСОБ ПОЛУЧЕНИЯ ПОПУЛЯЦИИ CD4+CD25+Foxp3+ Т-ЛИМФОЦИТОВ ЧЕЛОВЕКА ex vivo, СПОСОБ ЛЕЧЕНИЯ ЗАБОЛЕВАНИЯ |
| CA2742968C (en) | 2008-11-07 | 2020-06-09 | Fabrus Llc | Combinatorial antibody libraries and uses thereof |
| BR112012006388B1 (pt) | 2009-09-22 | 2022-01-04 | Probiogen Ag | Método para produzir uma molécula, e, método para produzir uma proteína |
| RS57280B1 (sr) * | 2009-12-21 | 2018-08-31 | Regeneron Pharma | Humanizovani fc gamma r miševi |
| AR079944A1 (es) | 2010-01-20 | 2012-02-29 | Boehringer Ingelheim Int | Anticuerpo neutralizante de la actividad de un anticoagulante |
| MX349662B (es) | 2010-07-22 | 2017-08-08 | Univ California | Anticuerpos de antigenos antitumorales y metodos de uso. |
| CN105377892A (zh) | 2013-03-15 | 2016-03-02 | 艾伯维生物技术有限公司 | 抗cd25抗体及其用途 |
| DK2970486T3 (en) | 2013-03-15 | 2018-08-06 | Xencor Inc | MODULATION OF T-CELLS WITH BISPECIFIC ANTIBODIES AND FC-FUSIONS |
| MX2015012563A (es) | 2013-03-15 | 2016-10-26 | Abbvie Biotechnology Ltd | Anticuerpos anti-cd25 y sus usos. |
| GB2526139A (en) | 2014-05-15 | 2015-11-18 | Biolnvent Internat Ab | Medicaments, uses and methods |
| US20170204154A1 (en) | 2016-01-20 | 2017-07-20 | Delinia, Inc. | Molecules that selectively activate regulatory t cells for the treatment of autoimmune diseases |
| KR20220032642A (ko) | 2016-04-07 | 2022-03-15 | 캔써 리서치 테크놀로지 리미티드 | 종양 특이적 세포 고갈을 위한 항 cd25 fc 감마 수용체 이중특이적 항체 |
| CA3041334A1 (en) | 2016-11-08 | 2018-05-17 | Delinia, Inc. | Il-2 variants for the treatment of autoimmune diseases |
| US11879014B2 (en) | 2017-03-17 | 2024-01-23 | Tusk Therapeutics Ltd. | Method of treating cancer or depleting regulatory T cells in a subject by administering a human IGG1 anti-CD25 antibody |
| UA129536C2 (uk) | 2018-03-13 | 2025-05-28 | Туск Терап'Ютікс Лтд | Анти-cd25 для виснаження пухлиноспецифічних клітин |
-
2018
- 2018-03-03 US US16/494,962 patent/US11879014B2/en active Active
- 2018-03-13 EP EP18711313.9A patent/EP3596123B1/en active Active
- 2018-03-13 KR KR1020197030283A patent/KR20190130137A/ko not_active Ceased
- 2018-03-13 LT LTEPPCT/EP2018/056312T patent/LT3596123T/lt unknown
- 2018-03-13 AU AU2018233976A patent/AU2018233976B2/en active Active
- 2018-03-13 JP JP2019550705A patent/JP2020514363A/ja active Pending
- 2018-03-13 SG SG11201908578Y patent/SG11201908578YA/en unknown
- 2018-03-13 SI SI201831085T patent/SI3596123T1/sl unknown
- 2018-03-13 ES ES18711313T patent/ES2975063T3/es active Active
- 2018-03-13 MX MX2019010974A patent/MX2019010974A/es unknown
- 2018-03-13 CA CA3056506A patent/CA3056506A1/en active Pending
- 2018-03-13 PL PL18711313.9T patent/PL3596123T3/pl unknown
- 2018-03-13 NZ NZ756984A patent/NZ756984A/en unknown
- 2018-03-13 RS RS20240376A patent/RS65351B1/sr unknown
- 2018-03-13 DK DK18711313.9T patent/DK3596123T3/da active
- 2018-03-13 MY MYPI2019005313A patent/MY208220A/en unknown
- 2018-03-13 FI FIEP18711313.9T patent/FI3596123T3/fi active
- 2018-03-13 HU HUE18711313A patent/HUE065999T2/hu unknown
- 2018-03-13 BR BR112019017017A patent/BR112019017017A2/pt unknown
- 2018-03-13 PE PE2019001847A patent/PE20191812A1/es unknown
- 2018-03-13 WO PCT/EP2018/056312 patent/WO2018167104A1/en not_active Ceased
- 2018-03-13 HR HRP20240469TT patent/HRP20240469T1/hr unknown
- 2018-03-13 CN CN201880018976.8A patent/CN110869388B/zh active Active
- 2018-03-13 CR CR20190477A patent/CR20190477A/es unknown
-
2019
- 2019-09-02 IL IL26908119A patent/IL269081A/en unknown
- 2019-09-13 CL CL2019002624A patent/CL2019002624A1/es unknown
-
2024
- 2024-01-25 JP JP2024009215A patent/JP2024050684A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CL2019002624A1 (es) | 2020-04-03 |
| PE20191812A1 (es) | 2019-12-26 |
| JP2020514363A (ja) | 2020-05-21 |
| CN110869388A (zh) | 2020-03-06 |
| US11879014B2 (en) | 2024-01-23 |
| IL269081A (en) | 2019-11-28 |
| JP2024050684A (ja) | 2024-04-10 |
| EP3596123A1 (en) | 2020-01-22 |
| WO2018167104A1 (en) | 2018-09-20 |
| HUE065999T2 (hu) | 2024-06-28 |
| NZ756984A (en) | 2025-08-29 |
| AU2018233976B2 (en) | 2025-03-20 |
| US20200010554A1 (en) | 2020-01-09 |
| SI3596123T1 (sl) | 2024-05-31 |
| ES2975063T3 (es) | 2024-07-03 |
| SG11201908578YA (en) | 2019-10-30 |
| CA3056506A1 (en) | 2018-09-20 |
| MX2019010974A (es) | 2020-08-03 |
| CN110869388B (zh) | 2024-09-20 |
| DK3596123T3 (da) | 2024-02-26 |
| CR20190477A (es) | 2020-01-07 |
| PL3596123T3 (pl) | 2024-06-24 |
| KR20190130137A (ko) | 2019-11-21 |
| LT3596123T (lt) | 2024-03-25 |
| AU2018233976A1 (en) | 2019-10-31 |
| HRP20240469T1 (hr) | 2024-07-19 |
| RS65351B1 (sr) | 2024-04-30 |
| MY208220A (en) | 2025-04-24 |
| EP3596123B1 (en) | 2024-01-10 |
| FI3596123T3 (fi) | 2024-04-17 |
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