BR112019012224A2 - compostos de benzimidazol como inibidores de c-kit - Google Patents
compostos de benzimidazol como inibidores de c-kit Download PDFInfo
- Publication number
- BR112019012224A2 BR112019012224A2 BR112019012224-9A BR112019012224A BR112019012224A2 BR 112019012224 A2 BR112019012224 A2 BR 112019012224A2 BR 112019012224 A BR112019012224 A BR 112019012224A BR 112019012224 A2 BR112019012224 A2 BR 112019012224A2
- Authority
- BR
- Brazil
- Prior art keywords
- methyl
- trifluoromethyl
- imidazol
- benzo
- ethynyl
- Prior art date
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- 102000016971 Proto-Oncogene Proteins c-kit Human genes 0.000 title claims abstract description 56
- 108010014608 Proto-Oncogene Proteins c-kit Proteins 0.000 title claims abstract description 56
- 239000003112 inhibitor Substances 0.000 title abstract description 8
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Landscapes
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| AU2004268949A1 (en) * | 2003-08-21 | 2005-03-10 | Osi Pharmaceuticals, Inc. | N-substituted benzimidazolyl C-kit inhibitors |
| JP2008521903A (ja) * | 2004-12-01 | 2008-06-26 | オーエスアイ・ファーマスーティカルズ・インコーポレーテッド | Ｎ置換されたベンズイミダゾリルＣ−ｋｉｔ阻害剤及びコンビナトリアルベンゾイミダゾールライブラリー |
| UA94055C2 (en) * | 2005-08-30 | 2011-04-11 | Новартис Аг | Substituted benzimidazoles and methods of preparation |
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| BR112013024171A2 (pt) * | 2011-04-07 | 2016-12-13 | Ariad Pharma Inc | método para o tratamento e prevenção de uma condição neurodegenerativa |
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2017
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- 2017-12-14 EP EP17822994.4A patent/EP3555066A1/en not_active Withdrawn
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- 2017-12-14 BR BR112019012224-9A patent/BR112019012224A2/pt not_active Application Discontinuation
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- 2017-12-14 KR KR1020197020159A patent/KR20190092538A/ko not_active Abandoned
- 2017-12-14 MA MA053150A patent/MA53150A/fr unknown
- 2017-12-14 IL IL314209A patent/IL314209A/en unknown
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2019
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2021
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2022
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2024
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|---|---|
| IL287517B1 (en) | 2024-08-01 |
| WO2018112140A1 (en) | 2018-06-21 |
| JP2022185110A (ja) | 2022-12-13 |
| CN110291081B (zh) | 2023-01-31 |
| JP2020503299A (ja) | 2020-01-30 |
| EP3555066A1 (en) | 2019-10-23 |
| CN116178343A (zh) | 2023-05-30 |
| IL267260B (en) | 2022-10-01 |
| IL267260B2 (en) | 2023-02-01 |
| AU2022201082A1 (en) | 2022-03-10 |
| AU2022201082B2 (en) | 2023-11-02 |
| CN116283910A (zh) | 2023-06-23 |
| MX390348B (es) | 2025-03-20 |
| MX2022002581A (es) | 2022-03-22 |
| MA53150A (fr) | 2021-05-26 |
| AU2017376629A1 (en) | 2019-07-04 |
| US20220064144A1 (en) | 2022-03-03 |
| IL267260A (en) | 2019-08-29 |
| CA3047107A1 (en) | 2018-06-21 |
| JP7158383B2 (ja) | 2022-10-21 |
| EA201991197A1 (ru) | 2020-01-13 |
| AU2017376629B2 (en) | 2021-11-25 |
| IL314209A (en) | 2024-09-01 |
| MX2019007080A (es) | 2019-10-15 |
| AU2024200624A1 (en) | 2024-02-22 |
| US20200039958A1 (en) | 2020-02-06 |
| KR20190092538A (ko) | 2019-08-07 |
| IL287517B2 (en) | 2024-12-01 |
| US11117883B2 (en) | 2021-09-14 |
| IL287517A (en) | 2021-12-01 |
| CN110291081A (zh) | 2019-09-27 |
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