BR112018074620A2 - método para a detecção de um anticorpo de igm específico para um flavivírus em uma amostra - Google Patents

método para a detecção de um anticorpo de igm específico para um flavivírus em uma amostra

Info

Publication number
BR112018074620A2
BR112018074620A2 BR112018074620-7A BR112018074620A BR112018074620A2 BR 112018074620 A2 BR112018074620 A2 BR 112018074620A2 BR 112018074620 A BR112018074620 A BR 112018074620A BR 112018074620 A2 BR112018074620 A2 BR 112018074620A2
Authority
BR
Brazil
Prior art keywords
flavivirus
igm
sample
detecting
binding
Prior art date
Application number
BR112018074620-7A
Other languages
English (en)
Inventor
X. Heinz Franz
Stiasny Karin
Original Assignee
Medizinische Universität Wien
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medizinische Universität Wien filed Critical Medizinische Universität Wien
Publication of BR112018074620A2 publication Critical patent/BR112018074620A2/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/18—Togaviridae; Flaviviridae
    • G01N2333/183—Flaviviridae, e.g. pestivirus, mucosal disease virus, bovine viral diarrhoea virus, classical swine fever virus (hog cholera virus) or border disease virus
    • G01N2333/185—Flaviviruses or Group B arboviruses, e.g. yellow fever virus, japanese encephalitis, tick-borne encephalitis, dengue
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)

Abstract

descrito é um método para a detecção de um anticorpo de igm específico para um flavivírus em uma amostra, compreendendo as etapas de, (a) contatar a amostra com um suporte sólido compreendendo moléculas de ligação de igm imobilizadas, (b) permitir ligação de anticorpos de igm na amostra às moléculas de ligação de igm no suporte sólido de forma que os anticorpos de igm sejam da mesma forma imobilizados no suporte sólido, e (c) detectar anticorpos de igm específicos para um flavivírus permitindo ligação de um complexo compreendendo (i) um dímero antiparalelo de proteína e de flavivírus solúvel (se) e (ii) um marcador e identificar a ligação do complexo ao anticorpo de igm de flavivírus específico detectando o marcador; e um kit adequado para realizar o método.
BR112018074620-7A 2016-06-06 2017-06-02 método para a detecção de um anticorpo de igm específico para um flavivírus em uma amostra BR112018074620A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16173043 2016-06-06
EP16173043.7 2016-06-06
PCT/EP2017/063446 WO2017211713A1 (en) 2016-06-06 2017-06-02 Method for the detection of an IgM antibody specific for a flavivirus in a sample

Publications (1)

Publication Number Publication Date
BR112018074620A2 true BR112018074620A2 (pt) 2019-03-06

Family

ID=56148121

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018074620-7A BR112018074620A2 (pt) 2016-06-06 2017-06-02 método para a detecção de um anticorpo de igm específico para um flavivírus em uma amostra

Country Status (9)

Country Link
US (1) US10591480B2 (pt)
EP (1) EP3465206B1 (pt)
JP (1) JP6908299B2 (pt)
AR (1) AR108771A1 (pt)
AU (1) AU2017277065A1 (pt)
BR (1) BR112018074620A2 (pt)
ES (1) ES2774497T3 (pt)
MX (1) MX2018015047A (pt)
WO (1) WO2017211713A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020061135A1 (en) * 2018-09-18 2020-03-26 Siemens Healthcare Diagnostics Inc. Methods and reagents for zika virus immunoassays
CN110132896A (zh) * 2019-05-06 2019-08-16 山西大学 一种快速检测血清中乳腺癌标志物的微型光纤生物传感器
US12066432B2 (en) 2019-06-05 2024-08-20 Gynuity Health Projects, Inc. Placental protein biomarkers for gestational age assessment and related methods

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4843000A (en) 1979-12-26 1989-06-27 Syntex (U.S.A.) Inc. Simultaneous calibration heterogeneous immunoassay
US4849338A (en) 1982-07-16 1989-07-18 Syntex (U.S.A.) Inc. Simultaneous calibration heterogeneous immunoassay
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
US5077391A (en) 1989-12-01 1991-12-31 Raison Robert L Purification of immunoglobulin M
US5112952A (en) 1990-09-28 1992-05-12 Pierce Chemical Company Composition and method for isolation and purification of Immunoglobulin M
EP0752425B1 (en) 1995-06-21 1999-09-29 TECNOGEN Società Consortile per azioni Peptide ligands for the constant region of immunoglobulins
ITMI962628A1 (it) 1996-12-16 1998-06-16 Tecnogen Scpa Composizione farmaceutica
JP2001511459A (ja) * 1997-07-31 2001-08-14 ハワイ バイオテクノロジー グループ， インコーポレイテッド フラビウイルス感染に対抗する組換え二量体エンベロープワクチン
AU6068000A (en) 1999-07-02 2001-01-22 Research And Development Institute, Inc. Peptide ligands that bind igm antibodies and block interaction with antigen
US20050287170A1 (en) * 2002-12-11 2005-12-29 Hawaii Biotech, Inc. Subunit vaccine against West Nile viral infection
WO2004052293A2 (en) 2002-12-11 2004-06-24 Hawaii Biotech, Inc. Recombinant vaccine against flavivirus infection
EP2003144A1 (en) 2007-06-15 2008-12-17 Institut Pasteur Method for the diagnosis or the screening of an arbovirus infection, reagents useful in said method and their applications
EP2272860A1 (en) 2009-07-10 2011-01-12 Institut Pasteur Multivalent epitope in complex with a detection marker for the early serodiagnosis of infections
GB201413086D0 (en) 2014-07-23 2014-09-03 Imp Innovations Ltd And Inst Pasteur Methods
EP2980099A1 (en) 2014-07-31 2016-02-03 Bernhard-Nocht-Institut für Tropenmedizin Compositions and methods for detecting flaviviridae infections
SG10201404571PA (en) 2014-08-01 2016-03-30 Mp Biomedicals Asia Pacific Pte Ltd Method and kit for detecting a dengue virus infection
EP3009841A1 (en) 2014-10-14 2016-04-20 Bernhard-Nocht-Institut für Tropenmedizin Detection of IgM Antibodies using an immune complex (IC) ELISA

Also Published As

Publication number Publication date
ES2774497T3 (es) 2020-07-21
US20190170750A1 (en) 2019-06-06
US10591480B2 (en) 2020-03-17
EP3465206A1 (en) 2019-04-10
WO2017211713A1 (en) 2017-12-14
MX2018015047A (es) 2019-05-13
AR108771A1 (es) 2018-09-26
EP3465206B1 (en) 2019-12-04
AU2017277065A1 (en) 2019-01-17
JP2019527837A (ja) 2019-10-03
JP6908299B2 (ja) 2021-07-21

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Legal Events

Date Code Title Description
B350 Update of information on the portal [chapter 15.35 patent gazette]
B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2777 DE 26-03-2024 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.