BR112018002448A2 - grandes arcabouços porosos 3d fabricados de hidroxiapatita ativa obtida por transformação biomórfica de estruturas naturais e processo para obter os mesmos - Google Patents
grandes arcabouços porosos 3d fabricados de hidroxiapatita ativa obtida por transformação biomórfica de estruturas naturais e processo para obter os mesmosInfo
- Publication number
- BR112018002448A2 BR112018002448A2 BR112018002448-1A BR112018002448A BR112018002448A2 BR 112018002448 A2 BR112018002448 A2 BR 112018002448A2 BR 112018002448 A BR112018002448 A BR 112018002448A BR 112018002448 A2 BR112018002448 A2 BR 112018002448A2
- Authority
- BR
- Brazil
- Prior art keywords
- wood
- hydroxyapatite
- bone
- hydroxyapatite obtained
- porous
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
- A61F2/2846—Support means for bone substitute or for bone graft implants, e.g. membranes or plates for covering bone defects
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/12—Phosphorus-containing materials, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3637—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the origin of the biological material other than human or animal, e.g. plant extracts, algae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
- A61L27/3645—Connective tissue
- A61L27/365—Bones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00179—Ceramics or ceramic-like structures
- A61F2310/00293—Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Transplantation (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Botany (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Vascular Medicine (AREA)
- Dispersion Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Materials For Medical Uses (AREA)
Abstract
a presente descrição se refere à hidroxiapatita obtida a partir de madeira porosa com uma resistência compressiva alta e dimensões apropriadas para aplicações clínicas. a madeira porosa apresenta uma porosidade entre 60% e 95%, sendo a referida porosidade medida depois de submeter a madeira a uma etapa de pirólise, e sendo selecionada de rattan, pinus, abacá balsa, sipo, carvalho, palisandro, bambus e madeira de nogueira. a hidroxiapatita pode ser substituída por um ou mais íons tais como, magnésio, estrôncio, silício, titânio, carbonato, potássio, sódio, prata, gálio, cobre, ferro, zinco, manganês, európio, gadolínio. também é revelado um substituto para o osso compreendendo hidroxiapatita obtida de madeira porosa. o substituto do osso é empregado para substituição e regeneração de um osso ou de uma porção óssea, preferivelmente para ossos submetidos às cargas mecânicas, tais como, ossos longos da perna e do braço, preferivelmente da tíbia, fíbula, fêmur, úmero e rádio. a invenção se refere também a um processo para fabricação de um arcabouço biomórfico de hidroxiapatita a partir de madeira.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT102015000042762 | 2015-08-06 | ||
| ITUB2015A002939A ITUB20152939A1 (it) | 2015-08-06 | 2015-08-06 | Processo per produrre grandi scaffold porosi in 3D realizzati in idrossiapatite attiva ottenuta tramite trasformazione biomorfica di strutture naturali? |
| ITUB2015A002962A ITUB20152962A1 (it) | 2015-08-06 | 2015-08-06 | Grandi scaffold porosi in 3D realizzati in idrossiapatite attiva ottenuta tramite trasformazione biomorfica di strutture naturali |
| IT102015000042834 | 2015-08-06 | ||
| PCT/IB2016/054665 WO2017021894A1 (en) | 2015-08-06 | 2016-08-03 | Large 3d porous scaffolds made of active hydroxyapatite obtained by biomorphic transformation of natural structures and process for obtaining them |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112018002448A2 true BR112018002448A2 (pt) | 2018-09-18 |
| BR112018002448B1 BR112018002448B1 (pt) | 2021-10-13 |
Family
ID=56842974
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112018002448-1A BR112018002448B1 (pt) | 2015-08-06 | 2016-08-03 | Grandes arcabouços porosos 3d fabricados de hidroxiapatita ativa obtida por transformação biomórfica de estruturas naturais e processo para obter os mesmos |
Country Status (24)
| Country | Link |
|---|---|
| US (3) | US10688218B2 (pt) |
| EP (2) | EP3331580B1 (pt) |
| JP (1) | JP6965482B2 (pt) |
| KR (1) | KR20180048678A (pt) |
| CN (1) | CN108348637B (pt) |
| AU (1) | AU2016304431B2 (pt) |
| BR (1) | BR112018002448B1 (pt) |
| CA (1) | CA2994049A1 (pt) |
| DK (1) | DK3331580T3 (pt) |
| EA (1) | EA035416B1 (pt) |
| ES (1) | ES2758357T3 (pt) |
| HR (1) | HRP20192181T1 (pt) |
| HU (1) | HUE046337T2 (pt) |
| IL (1) | IL257241B (pt) |
| LT (1) | LT3331580T (pt) |
| MX (1) | MX2018001516A (pt) |
| MY (1) | MY185917A (pt) |
| PH (1) | PH12018500272A1 (pt) |
| PL (1) | PL3331580T4 (pt) |
| PT (1) | PT3331580T (pt) |
| SI (1) | SI3331580T1 (pt) |
| UA (1) | UA125283C2 (pt) |
| WO (1) | WO2017021894A1 (pt) |
| ZA (1) | ZA201801355B (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108498860B (zh) * | 2018-03-30 | 2020-09-08 | 西南交通大学 | 一种利用金属元素掺杂羟基磷灰石制备3d陶瓷支架的方法 |
| IT201800007993A1 (it) | 2018-08-09 | 2020-02-09 | Greenbone Ortho Srl | Impianto finalizzato alla trasformazione chimica di materiali nello stato 3d |
| ES2922210T3 (es) * | 2019-08-16 | 2022-09-09 | Univ Heidelberg | Sustitución osteotrópica de hueso |
| CN111249523B (zh) * | 2020-03-10 | 2021-07-13 | 四川大学 | 仿骨复合材料支架及其制备方法 |
| KR102711590B1 (ko) * | 2021-05-06 | 2024-09-30 | 충북대학교 산학협력단 | 약물 담지용 다공성 수산화아파타이트 구조체의 제조 방법, 및 이로부터 제조된 약물 담지체 |
| CN114699561B (zh) * | 2021-12-30 | 2023-03-31 | 佛山市中医院 | 一种掺杂钙基材料、骨修复材料及其制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI108403B (fi) * | 2000-02-25 | 2002-01-31 | Yli Urpo Antti | Yksil÷n kudosrekonstruktioon soveltuva materiaali |
| WO2004103422A1 (ja) * | 2003-05-26 | 2004-12-02 | Pentax Corporation | リン酸カルシウム含有複合多孔体及びその製造方法 |
| JP2005066354A (ja) | 2004-10-01 | 2005-03-17 | Takiron Co Ltd | 複合化された骨接合材 |
| WO2006099332A2 (en) * | 2005-03-11 | 2006-09-21 | Wake Forest University Health Sciences | Production of tissue engineered digits and limbs |
| CN101829363B (zh) * | 2010-05-28 | 2013-08-14 | 西安交通大学 | 一种骨组织工程仿生支架材料的制备方法 |
| ITMI20102070A1 (it) | 2010-11-08 | 2012-05-09 | Consiglio Nazionale Ricerche | Impianti per sostituzioni ossee "load bearing" ad architettura gerarchicamente organizzata derivante dalla trasformazione di strutture vegetali |
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2016
- 2016-08-03 LT LTEP16757963.0T patent/LT3331580T/lt unknown
- 2016-08-03 HU HUE16757963A patent/HUE046337T2/hu unknown
- 2016-08-03 WO PCT/IB2016/054665 patent/WO2017021894A1/en active Application Filing
- 2016-08-03 BR BR112018002448-1A patent/BR112018002448B1/pt active IP Right Grant
- 2016-08-03 EP EP16757963.0A patent/EP3331580B1/en active Active
- 2016-08-03 ES ES16757963T patent/ES2758357T3/es active Active
- 2016-08-03 MY MYPI2018700399A patent/MY185917A/en unknown
- 2016-08-03 CN CN201680046287.9A patent/CN108348637B/zh active Active
- 2016-08-03 PT PT167579630T patent/PT3331580T/pt unknown
- 2016-08-03 PL PL16757963T patent/PL3331580T4/pl unknown
- 2016-08-03 SI SI201630494T patent/SI3331580T1/sl unknown
- 2016-08-03 UA UAA201801339A patent/UA125283C2/uk unknown
- 2016-08-03 AU AU2016304431A patent/AU2016304431B2/en active Active
- 2016-08-03 US US15/750,568 patent/US10688218B2/en active Active
- 2016-08-03 MX MX2018001516A patent/MX2018001516A/es active IP Right Grant
- 2016-08-03 CA CA2994049A patent/CA2994049A1/en active Pending
- 2016-08-03 EP EP19188200.0A patent/EP3590544B1/en active Active
- 2016-08-03 DK DK16757963T patent/DK3331580T3/da active
- 2016-08-03 JP JP2018525825A patent/JP6965482B2/ja active Active
- 2016-08-03 KR KR1020187006371A patent/KR20180048678A/ko not_active Application Discontinuation
- 2016-08-03 EA EA201890291A patent/EA035416B1/ru not_active IP Right Cessation
-
2018
- 2018-01-30 IL IL257241A patent/IL257241B/en active IP Right Grant
- 2018-02-06 PH PH12018500272A patent/PH12018500272A1/en unknown
- 2018-02-27 ZA ZA2018/01355A patent/ZA201801355B/en unknown
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2019
- 2019-12-03 HR HRP20192181TT patent/HRP20192181T1/hr unknown
-
2020
- 2020-05-15 US US16/875,554 patent/US11213605B2/en active Active
- 2020-05-15 US US16/875,543 patent/US11357886B2/en active Active
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 03/08/2016, OBSERVADAS AS CONDICOES LEGAIS. |
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| B25D | Requested change of name of applicant approved |
Owner name: GREENBONE ORTHO S.P.A. (IT) |