BR112017018823A2 - compostos antifúngicos e processos para a fabricação - Google Patents

compostos antifúngicos e processos para a fabricação

Info

Publication number
BR112017018823A2
BR112017018823A2 BR112017018823-6A BR112017018823A BR112017018823A2 BR 112017018823 A2 BR112017018823 A2 BR 112017018823A2 BR 112017018823 A BR112017018823 A BR 112017018823A BR 112017018823 A2 BR112017018823 A2 BR 112017018823A2
Authority
BR
Brazil
Prior art keywords
processes
manufacturing
antifungal compounds
compound
polymorphs
Prior art date
Application number
BR112017018823-6A
Other languages
English (en)
Inventor
J. Hoekstra William
Dale Wirth David
EHIWE Tracy
Bonnaud Thierry
Original Assignee
Viamet Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Viamet Pharmaceuticals, Inc. filed Critical Viamet Pharmaceuticals, Inc.
Publication of BR112017018823A2 publication Critical patent/BR112017018823A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B63/00—Purification; Separation; Stabilisation; Use of additives
    • C07B63/04—Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Abstract

a presente invenção refere-se às formas polimórficas do composto 1 ou 1a e processos para a preparação de polimorfos do composto 1 e 1a, que são úteis como agentes antifúngicos. em particular, a invenção procura fornecer uma nova metodologia para a preparação de polimorfos do composto 1 e seus derivados substituídos.
BR112017018823-6A 2015-03-19 2016-03-17 compostos antifúngicos e processos para a fabricação BR112017018823A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562135682P 2015-03-19 2015-03-19
US62/135,682 2015-03-19
PCT/US2016/022858 WO2016149486A1 (en) 2015-03-19 2016-03-17 Antifungal compounds and processes for making

Publications (1)

Publication Number Publication Date
BR112017018823A2 true BR112017018823A2 (pt) 2018-04-24

Family

ID=56919372

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017018823-6A BR112017018823A2 (pt) 2015-03-19 2016-03-17 compostos antifúngicos e processos para a fabricação

Country Status (19)

Country Link
US (4) US9840492B2 (pt)
EP (1) EP3271347B1 (pt)
KR (1) KR102603277B1 (pt)
CN (1) CN107428724B (pt)
AU (1) AU2016233113B2 (pt)
BR (1) BR112017018823A2 (pt)
CA (1) CA2978339C (pt)
DK (1) DK3271347T3 (pt)
EA (1) EA037556B1 (pt)
ES (1) ES2926063T3 (pt)
HR (1) HRP20221113T1 (pt)
HU (1) HUE059771T2 (pt)
LT (1) LT3271347T (pt)
MX (1) MX2017012021A (pt)
PL (1) PL3271347T3 (pt)
PT (1) PT3271347T (pt)
RS (1) RS63566B1 (pt)
SI (1) SI3271347T1 (pt)
WO (1) WO2016149486A1 (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2788343T (pt) 2011-12-11 2018-06-01 Viamet Pharmaceuticals Nc Inc Compostos inibidores de metaloenzimas
JP6633539B2 (ja) * 2014-03-19 2020-01-22 ダウ アグロサイエンシィズ エルエルシー ２−（２，４−ジフルオロフェニル）−１，１−ジフルオロ−１−（５−置換−ピリジン−２−イル）−３−（１ｈ−テトラゾール−１−イル）プロパン−２−オールおよびその調製工程
JP2017509646A (ja) 2014-03-19 2017-04-06 ヴィアメット ファーマスーティカルズ，インコーポレイテッド 抗真菌化合物の調製方法
MX369357B (es) 2014-03-19 2019-11-06 Mycovia Pharmaceuticals Inc Procedimiento de compuesto antifungico.
AU2015231216B2 (en) 2014-03-19 2019-04-04 Mycovia Pharmaceuticals, Inc. Antifungal compound process
MX371291B (es) 2014-03-19 2020-01-24 Viamet Pharmaceuticals Nc Inc 2-(2,4-difluorofenil)-1,1-difluoro-1-(5-sustituido-piridin-2-il)- 3-(1h-tetrazol-1-il)propan-2-oles y procedimientos para su preparacion.
EP3119754A4 (en) 2014-03-19 2017-12-13 Viamet Pharmaceuticals, Inc. Antifungal compound process
JP2017507991A (ja) 2014-03-19 2017-03-23 ヴィアメット ファーマスーティカルズ，インコーポレイテッド 抗真菌化合物の調製方法
EP3119746A4 (en) 2014-03-19 2017-08-16 Viamet Pharmaceuticals, Inc. Antifungal compound process
EP3119745B1 (en) 2014-03-19 2020-08-05 Mycovia Pharmaceuticals, Inc. Antifungal compound process
HRP20221113T1 (hr) * 2015-03-19 2022-11-25 Mycovia Pharmaceuticals, Inc. Antifungalni spojevi i procesi izrade
US10464921B2 (en) 2015-09-18 2019-11-05 Mycovia Pharmaceuticals, Inc. Antifungal compound process
WO2021188404A1 (en) 2020-03-19 2021-09-23 Assia Chemical Industries Ltd Solid state forms of oteseconazole and process for preparation thereof
CA3226998A1 (en) * 2021-07-22 2023-01-26 Mycovia Pharmaceuticals, Inc. Compositions comprising oteseconazole
WO2024067784A1 (zh) * 2022-09-30 2024-04-04 上海济煜医药科技有限公司 双环类化合物的无定形、结晶固体及其制备方法

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US5087240A (en) 1983-08-18 1992-02-11 Drug Delivery Systems Inc. Transdermal drug patch with conductive fibers
US4921475A (en) 1983-08-18 1990-05-01 Drug Delivery Systems Inc. Transdermal drug patch with microtubes
US5163899A (en) 1987-03-20 1992-11-17 Drug Delivery Systems Inc. Transdermal drug delivery system
US5312325A (en) 1987-05-28 1994-05-17 Drug Delivery Systems Inc Pulsating transdermal drug delivery system
GB8804164D0 (en) 1988-02-23 1988-03-23 Tucker J M Bandage for administering physiologically active compound
US5008110A (en) 1988-11-10 1991-04-16 The Procter & Gamble Company Storage-stable transdermal patch
US5088977A (en) 1988-12-21 1992-02-18 Drug Delivery Systems Inc. Electrical transdermal drug applicator with counteractor and method of drug delivery
DE69009946T2 (de) 1989-12-04 1994-11-03 Searle & Co System zur transdermalen Albuterol Applikation.
US5352456A (en) 1991-10-10 1994-10-04 Cygnus Therapeutic Systems Device for administering drug transdermally which provides an initial pulse of drug
EP0617665B1 (en) 1991-12-18 1999-03-31 Minnesota Mining And Manufacturing Company Multilayered barrier structures
ATE132381T1 (de) 1992-01-29 1996-01-15 Voelkl Franz Ski Ballspielschläger, insbesondere tennisschläger
EP2767539B1 (en) 2002-05-16 2017-07-12 Janssen Sciences Ireland UC Pseudopolymorphic forms of a HIV protease inhibitor
US7968579B2 (en) 2005-10-31 2011-06-28 Daewoong Pharmaceutical Co., Ltd. Antifungal triazole derivatives
DE102008043697A1 (de) 2008-01-25 2009-07-30 Robert Bosch Gmbh Verfahren und Vorrichtung zur Bestimmung der Zusammensetzung eines Kraftstoffgemischs
JP5266430B2 (ja) 2010-04-24 2013-08-21 ヴィアメット ファーマスーティカルズ，インコーポレイテッド 金属酵素阻害化合物
DK2804858T3 (da) * 2012-01-20 2020-03-16 Mycovia Pharmaceuticals Inc Metalloenzym-inhibitorforbindelser
BR112014017799A8 (pt) * 2012-01-20 2017-07-11 Viamet Pharmaceuticals Inc Compostos inibidores de metaloenzima
ITFI20120143A1 (it) * 2012-07-12 2014-01-13 Inalco S A S Di Giovanni Cipollett I & C Polimorfi idrati e anidri del 2'-o-fucosillattosio e loro metodi di produzione.
EP3119745B1 (en) * 2014-03-19 2020-08-05 Mycovia Pharmaceuticals, Inc. Antifungal compound process
HRP20221113T1 (hr) * 2015-03-19 2022-11-25 Mycovia Pharmaceuticals, Inc. Antifungalni spojevi i procesi izrade

Also Published As

Publication number Publication date
CA2978339A1 (en) 2016-09-22
EA037556B1 (ru) 2021-04-14
US10676459B2 (en) 2020-06-09
CA2978339C (en) 2021-08-03
WO2016149486A1 (en) 2016-09-22
KR20170129895A (ko) 2017-11-27
CN107428724A (zh) 2017-12-01
EP3271347A1 (en) 2018-01-24
AU2016233113A1 (en) 2017-09-21
US9840492B2 (en) 2017-12-12
US20190210994A1 (en) 2019-07-11
US20180319768A1 (en) 2018-11-08
AU2016233113B2 (en) 2020-05-07
CN107428724B (zh) 2021-07-02
KR102603277B1 (ko) 2023-11-17
US10370353B2 (en) 2019-08-06
EA201792067A1 (ru) 2018-01-31
EP3271347B1 (en) 2022-06-22
LT3271347T (lt) 2022-10-10
PT3271347T (pt) 2022-07-14
ES2926063T3 (es) 2022-10-21
US20190367476A1 (en) 2019-12-05
HRP20221113T1 (hr) 2022-11-25
MX2017012021A (es) 2018-01-30
US10414751B2 (en) 2019-09-17
US20170121307A1 (en) 2017-05-04
EP3271347A4 (en) 2018-10-17
DK3271347T3 (da) 2022-07-18
RS63566B1 (sr) 2022-10-31
HUE059771T2 (hu) 2022-12-28
PL3271347T3 (pl) 2022-11-21
SI3271347T1 (sl) 2022-11-30

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Legal Events

Date Code Title Description
B25D Requested change of name of applicant approved

Owner name: VIAMET PHARMACEUTICALS (NC), INC. (US)

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]