BR112017018119A2 - processo para a preparação de triazóis - Google Patents

processo para a preparação de triazóis

Info

Publication number
BR112017018119A2
BR112017018119A2 BR112017018119A BR112017018119A BR112017018119A2 BR 112017018119 A2 BR112017018119 A2 BR 112017018119A2 BR 112017018119 A BR112017018119 A BR 112017018119A BR 112017018119 A BR112017018119 A BR 112017018119A BR 112017018119 A2 BR112017018119 A2 BR 112017018119A2
Authority
BR
Brazil
Prior art keywords
triazoles
preparation
starch
substituted
discloses
Prior art date
Application number
BR112017018119A
Other languages
English (en)
Other versions
BR112017018119B1 (pt
Inventor
W J Kennedy Jason
Von Morgenstern Sascha
Original Assignee
Bayer Cropscience Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Cropscience Ag filed Critical Bayer Cropscience Ag
Publication of BR112017018119A2 publication Critical patent/BR112017018119A2/pt
Publication of BR112017018119B1 publication Critical patent/BR112017018119B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4192—1,2,3-Triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/12—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
    • C07C259/14—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/46—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having at least one of the nitrogen atoms, not being part of nitro or nitroso groups, further bound to other hetero atoms
    • C07C323/47—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having at least one of the nitrogen atoms, not being part of nitro or nitroso groups, further bound to other hetero atoms to oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • C07D249/06—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles with aryl radicals directly attached to ring atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

processo para a preparação de triazóis. a presente invenção divulga a preparação eficiente de 2-substituído-4-amido-1,2,3-triazóis.
BR112017018119-3A 2015-02-24 2016-02-19 Processo para a preparação de triazóis BR112017018119B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15156316.0 2015-02-24
EP15156316 2015-02-24
PCT/EP2016/053570 WO2016135062A1 (en) 2015-02-24 2016-02-19 Process for the preparation of triazoles

Publications (2)

Publication Number Publication Date
BR112017018119A2 true BR112017018119A2 (pt) 2018-04-10
BR112017018119B1 BR112017018119B1 (pt) 2021-11-03

Family

ID=52573627

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017018119-3A BR112017018119B1 (pt) 2015-02-24 2016-02-19 Processo para a preparação de triazóis

Country Status (12)

Country Link
US (1) US10611734B2 (pt)
EP (1) EP3262027B1 (pt)
JP (2) JP6728205B2 (pt)
KR (1) KR20170120599A (pt)
CN (1) CN107207461B (pt)
BR (1) BR112017018119B1 (pt)
DK (1) DK3262027T3 (pt)
ES (1) ES2929355T3 (pt)
IL (1) IL253562B (pt)
MX (1) MX2017010899A (pt)
TW (1) TWI705056B (pt)
WO (1) WO2016135062A1 (pt)

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1168437B (de) 1962-11-17 1964-04-23 Hoechst Ag Verfahren zur Herstellung von 4-Nitro-1, 2, 3-triazolen
OA09122A (en) 1988-07-08 1991-10-31 Schering Agrochemicals Ltd Triazole insecticides.
DE19858191A1 (de) 1998-12-17 2000-06-21 Aventis Cropscience Gmbh 4-Haloalkyl-3-heterocyclylpyridine und 4-Haloalkyl-5-heterocyclyl-pyrimidine und ihre Verwendung als Repellentien
JP2006506340A (ja) 2002-08-09 2006-02-23 アストラゼネカ アクチボラグ 代謝調節型グルタミン酸受容体５のモジュレーターとしてのオキサジアゾール
JPWO2014051055A1 (ja) 2012-09-28 2016-08-22 東レ株式会社 キヌクリジンウレア誘導体及びその医薬用途
MX2015004275A (es) 2012-10-02 2015-08-14 Bayer Cropscience Ag Compuestos heterociclicos como plaguicidas.
CA2891412A1 (en) 2012-11-20 2014-05-30 Vertex Pharmaceuticals Incorporated Compounds useful as inhibitors of indoleamine 2,3-dioxygenase
PT2925745T (pt) * 2012-11-29 2018-08-08 Chemocentryx Inc Antagonistas de cxcr7
US9431714B2 (en) 2013-01-03 2016-08-30 Taiwan Semiconductor Manufacturing Co., Ltd. Antenna structures
WO2014113303A1 (en) 2013-01-16 2014-07-24 Merck Sharp & Dohme Corp. 4-fluoropiperidine orexin receptor antagonists
AR096393A1 (es) * 2013-05-23 2015-12-30 Bayer Cropscience Ag Compuestos heterocíclicos pesticidas

Also Published As

Publication number Publication date
DK3262027T3 (da) 2022-11-21
TWI705056B (zh) 2020-09-21
JP2020169193A (ja) 2020-10-15
BR112017018119B1 (pt) 2021-11-03
TW201636335A (zh) 2016-10-16
KR20170120599A (ko) 2017-10-31
CN107207461A (zh) 2017-09-26
EP3262027B1 (en) 2022-08-31
EP3262027A1 (en) 2018-01-03
US10611734B2 (en) 2020-04-07
JP6728205B2 (ja) 2020-07-22
IL253562A0 (en) 2017-09-28
WO2016135062A1 (en) 2016-09-01
JP2018507859A (ja) 2018-03-22
ES2929355T3 (es) 2022-11-28
IL253562B (en) 2021-07-29
MX2017010899A (es) 2017-11-24
US20180050995A1 (en) 2018-02-22
CN107207461B (zh) 2022-11-15

Similar Documents

Publication Publication Date Title
CL2020001852A1 (es) Procesos de preparación de s-ketamina o clorhidrato de s-ketamina o productos derivados de éste. (divisional solicitud 201901066)
BR112018010089A2 (pt) composições compreendendo cepas bacterianas
BR112019006160A2 (pt) composições e métodos para o tratamento das condições oftálmicas
BR112017003414A2 (pt) composições compreendendo caseína e métodos para produzir as mesmas
EP3380199A4 (en) DEVICE FOR TREATING HAIR
IL261046B (en) Substituted 1,2,3-triazoles as nr2b-selective nmda modulators
AU2019268074A1 (en) Methods for treating hepcidin-mediated disorders
EP3380200A4 (en) COMPOSITIONS FOR THE TREATMENT OF HAIR
EP3380062A4 (en) COMPOSITIONS FOR TREATING THE HAIR
SV2017005586A (es) Procesos e intermediarios para la preparacion de {1- (etilsulfonil) -3- [4 -(7h -pirrolo [2, 3-d] pirimidin -4- il) -1h -pirazol -1- il] azetidin -3- il} acetonitrilo
EP3380063A4 (en) COMPOSITIONS FOR THE TREATMENT OF HAIR
EP3516651A4 (en) TECHNOLOGIES FOR IMPROVED KEYWORD DETECTION
MA40457A (fr) Combinaison de médicaments pour traiter le myélome multiple
PH12017501864A1 (en) Compositions and methods for treating autism
BR112015019924A2 (pt) métodos e composições para tratar leucemia
MX2021012440A (es) Farmacos precursores de oxabicicloheptanos.
BR112018003800A2 (pt) derivados de 1,7-diaril-1,6-heptadieno-3,5-diona, processo para a sua produção e utilização
MX2019004182A (es) Proceso para la fabricacion de 2,6-dimetil-5-hepten-1-al.
PL3559963T3 (pl) Zespolony transformator miernikowy prądowy i napięciowy do zastosowań wysokiego napięcia
CL2016001745A1 (es) Ácido (s)-3'-metil-abscísico y ésteres del mismo
ITUA20161635A1 (it) "Sorgente laser, particolarmente per lavorazioni industriali"
BR112017002139A2 (pt) ?método para preparar um composto?
EA201692246A1 (ru) Способ получения 2,6-диметилбензохинона
CL2016002256A1 (es) Un proceso mejorado para la preparación de exametazima
MX2016017019A (es) Metodo para la preparacion de 4-alcoxi-1,1,1-trifluorobut-3-en-2-o nas de 1,1,1 trifluoroacetona.

Legal Events

Date Code Title Description
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 19/02/2016, OBSERVADAS AS CONDICOES LEGAIS.