BR112015019924A2 - métodos e composições para tratar leucemia - Google Patents
métodos e composições para tratar leucemiaInfo
- Publication number
- BR112015019924A2 BR112015019924A2 BR112015019924A BR112015019924A BR112015019924A2 BR 112015019924 A2 BR112015019924 A2 BR 112015019924A2 BR 112015019924 A BR112015019924 A BR 112015019924A BR 112015019924 A BR112015019924 A BR 112015019924A BR 112015019924 A2 BR112015019924 A2 BR 112015019924A2
- Authority
- BR
- Brazil
- Prior art keywords
- compositions
- methods
- treating leukemia
- leukemia
- treating
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/133—Amines having hydroxy groups, e.g. sphingosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C50/00—Quinones
- C07C50/26—Quinones containing groups having oxygen atoms singly bound to carbon atoms
- C07C50/28—Quinones containing groups having oxygen atoms singly bound to carbon atoms with monocyclic quinoid structure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Abstract
resumo métodos e composições para tratar leucemia a presente invenção proporciona métodos e composições para o tratamento de leucemia por compostos de ciclohexenona.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361767211P | 2013-02-20 | 2013-02-20 | |
PCT/US2014/017285 WO2014130619A2 (en) | 2013-02-20 | 2014-02-20 | Methods and compositions for treating leukemia |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112015019924A2 true BR112015019924A2 (pt) | 2017-07-18 |
Family
ID=51391965
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112015019924A BR112015019924A2 (pt) | 2013-02-20 | 2014-02-20 | métodos e composições para tratar leucemia |
Country Status (16)
Country | Link |
---|---|
US (1) | US9403747B2 (pt) |
EP (1) | EP2958558B1 (pt) |
JP (1) | JP6501123B2 (pt) |
KR (1) | KR102054038B1 (pt) |
CN (2) | CN108309961A (pt) |
AU (1) | AU2014218938B2 (pt) |
BR (1) | BR112015019924A2 (pt) |
CA (1) | CA2901745A1 (pt) |
DK (1) | DK2958558T3 (pt) |
ES (1) | ES2687286T3 (pt) |
HK (2) | HK1219884A1 (pt) |
MX (1) | MX2015010728A (pt) |
PL (1) | PL2958558T3 (pt) |
TW (1) | TWI597061B (pt) |
WO (1) | WO2014130619A2 (pt) |
ZA (1) | ZA201506330B (pt) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109069448B (zh) * | 2016-02-17 | 2021-09-21 | 国鼎生物科技股份有限公司 | 用于治疗肝癌的组合物和方法 |
SG11201810082VA (en) * | 2016-05-13 | 2018-12-28 | Golden Biotechnology Corp | Methods and compositions for treating advanced stage non-small cell lung cancer |
TWI601535B (zh) * | 2016-06-23 | 2017-10-11 | 台灣利得生物科技股份有限公司 | 牛樟段木栽培牛樟芝子實體及固態培養菌絲體水及乙醇萃取物之組合物應用於抗癌藥輔助劑 |
CN107540641A (zh) * | 2016-06-29 | 2018-01-05 | 彭朗 | 一种新的有机酯类化合物及其制备方法和医药用途 |
US10314241B1 (en) * | 2016-09-14 | 2019-06-11 | T. Scott Dunn | Airborne vegetation cutting assembly |
US11406605B2 (en) * | 2017-12-20 | 2022-08-09 | Golden Biotechnology Corporation | Therapeutic compositions for treating pancreatic cancer |
EP3930724A4 (en) * | 2019-02-25 | 2022-11-23 | Arjil Biotech Holding Company Limited | METHOD AND COMPOSITION FOR INHIBITING VIRAL INFECTION |
US11548069B2 (en) | 2019-05-20 | 2023-01-10 | Wisconsin Alumni Research Foundation | Three-dimensional printer laminating fusible sheets |
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US3598123A (en) | 1969-04-01 | 1971-08-10 | Alza Corp | Bandage for administering drugs |
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US3598122A (en) | 1969-04-01 | 1971-08-10 | Alza Corp | Bandage for administering drugs |
US3710795A (en) | 1970-09-29 | 1973-01-16 | Alza Corp | Drug-delivery device with stretched, rate-controlling membrane |
US4069307A (en) | 1970-10-01 | 1978-01-17 | Alza Corporation | Drug-delivery device comprising certain polymeric materials for controlled release of drug |
US3731683A (en) | 1971-06-04 | 1973-05-08 | Alza Corp | Bandage for the controlled metering of topical drugs to the skin |
US3996934A (en) | 1971-08-09 | 1976-12-14 | Alza Corporation | Medical bandage |
US3742951A (en) | 1971-08-09 | 1973-07-03 | Alza Corp | Bandage for controlled release of vasodilators |
BE795384A (fr) | 1972-02-14 | 1973-08-13 | Ici Ltd | Pansements |
US3921636A (en) | 1973-01-15 | 1975-11-25 | Alza Corp | Novel drug delivery device |
US3993072A (en) | 1974-08-28 | 1976-11-23 | Alza Corporation | Microporous drug delivery device |
US3972995A (en) | 1975-04-14 | 1976-08-03 | American Home Products Corporation | Dosage form |
US4077407A (en) | 1975-11-24 | 1978-03-07 | Alza Corporation | Osmotic devices having composite walls |
US4031894A (en) | 1975-12-08 | 1977-06-28 | Alza Corporation | Bandage for transdermally administering scopolamine to prevent nausea |
US4060084A (en) | 1976-09-07 | 1977-11-29 | Alza Corporation | Method and therapeutic system for providing chemotherapy transdermally |
US4201211A (en) | 1977-07-12 | 1980-05-06 | Alza Corporation | Therapeutic system for administering clonidine transdermally |
JPS5562012A (en) | 1978-11-06 | 1980-05-10 | Teijin Ltd | Slow-releasing preparation |
US4230105A (en) | 1978-11-13 | 1980-10-28 | Merck & Co., Inc. | Transdermal delivery of drugs |
US4291015A (en) | 1979-08-14 | 1981-09-22 | Key Pharmaceuticals, Inc. | Polymeric diffusion matrix containing a vasodilator |
US5312325A (en) | 1987-05-28 | 1994-05-17 | Drug Delivery Systems Inc | Pulsating transdermal drug delivery system |
US5633009A (en) | 1990-11-28 | 1997-05-27 | Sano Corporation | Transdermal administration of azapirones |
US5665378A (en) | 1994-09-30 | 1997-09-09 | Davis; Roosevelt | Transdermal therapeutic formulation |
US6923983B2 (en) | 1996-02-19 | 2005-08-02 | Acrux Dds Pty Ltd | Transdermal delivery of hormones |
US6929801B2 (en) | 1996-02-19 | 2005-08-16 | Acrux Dds Pty Ltd | Transdermal delivery of antiparkinson agents |
US5905089A (en) * | 1997-04-14 | 1999-05-18 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Use of sesquiterpene lactones for treatment of severe inflammatory disorders |
US5869090A (en) | 1998-01-20 | 1999-02-09 | Rosenbaum; Jerry | Transdermal delivery of dehydroepiandrosterone |
US6946144B1 (en) | 1998-07-08 | 2005-09-20 | Oryxe | Transdermal delivery system |
US20070287672A1 (en) * | 2004-04-20 | 2007-12-13 | Donald Creighton | Macromolecular Gsh-Activiated Glyoxylase I Inhibitors |
CA2581372A1 (en) * | 2004-09-30 | 2006-04-13 | Ariad Gene Therapeutics, Inc. | Treatment method |
CN101343247B (zh) * | 2007-07-12 | 2011-01-19 | 国鼎生物科技股份有限公司 | 牛樟芝的环己烯酮萃取物 |
TW200918498A (en) * | 2007-10-19 | 2009-05-01 | Golden Biotechnology Corp | Novel compound isolated from Antrodia camphorate extracts |
TWI389699B (zh) * | 2009-02-13 | 2013-03-21 | Univ Kaohsiung Medical | 用於誘導細胞凋亡之樟芝子實體乙醇萃取物及其製備方法 |
TW201102075A (en) * | 2009-07-09 | 2011-01-16 | Golden Biotechnology Corp | Cyclohexenone compound of Antrodia cinnomomea that suppresses growth of tumor cell of pancreatic cancer |
TW201109013A (en) * | 2009-09-09 | 2011-03-16 | Golden Biotechnology Corp | Cyclohexenone chemical compounds of Antrodia cinnamomea for suppressing the growth of the Lymphoma tumor cell |
EP2329816B1 (en) | 2009-11-26 | 2016-04-13 | National Taiwan University | An anti-cancer active substance from antrodia camphorata, method for preparing the same and use thereof |
CN102232942B (zh) * | 2010-05-06 | 2013-03-27 | 国鼎生物科技股份有限公司 | 用于抑制淋巴癌肿瘤细胞生长的牛樟芝环己烯酮化合物 |
US8309611B2 (en) * | 2010-09-20 | 2012-11-13 | Golden Biotechnology Corporation | Methods and compositions for treating lung cancer |
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MX2013014488A (es) * | 2011-06-10 | 2014-03-27 | Golden Biotechnology Corp | Metodos y composiciones para tratar el cancer cerebral. |
TWI484954B (zh) * | 2011-10-11 | 2015-05-21 | New Bellus Entpr Co Ltd | 用於治療癌症之醫藥組合物 |
WO2014151304A1 (en) * | 2013-03-15 | 2014-09-25 | Golden Biotechnology Corporation | Therapeutic methods and compositions utilizing cyclohexenone compounds |
-
2014
- 2014-02-19 TW TW103105416A patent/TWI597061B/zh active
- 2014-02-20 ES ES14754927.3T patent/ES2687286T3/es active Active
- 2014-02-20 AU AU2014218938A patent/AU2014218938B2/en active Active
- 2014-02-20 KR KR1020157025170A patent/KR102054038B1/ko active IP Right Grant
- 2014-02-20 MX MX2015010728A patent/MX2015010728A/es unknown
- 2014-02-20 EP EP14754927.3A patent/EP2958558B1/en active Active
- 2014-02-20 WO PCT/US2014/017285 patent/WO2014130619A2/en active Application Filing
- 2014-02-20 JP JP2015558939A patent/JP6501123B2/ja active Active
- 2014-02-20 CN CN201810367184.3A patent/CN108309961A/zh active Pending
- 2014-02-20 CN CN201480022525.3A patent/CN105246470A/zh active Pending
- 2014-02-20 US US14/184,982 patent/US9403747B2/en active Active
- 2014-02-20 DK DK14754927.3T patent/DK2958558T3/en active
- 2014-02-20 BR BR112015019924A patent/BR112015019924A2/pt not_active IP Right Cessation
- 2014-02-20 PL PL14754927T patent/PL2958558T3/pl unknown
- 2014-02-20 CA CA2901745A patent/CA2901745A1/en not_active Abandoned
-
2015
- 2015-08-28 ZA ZA2015/06330A patent/ZA201506330B/en unknown
-
2016
- 2016-07-07 HK HK16107933.7A patent/HK1219884A1/zh unknown
-
2018
- 2018-11-15 HK HK18114626.3A patent/HK1255453A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
ZA201506330B (en) | 2016-10-26 |
MX2015010728A (es) | 2016-04-11 |
US9403747B2 (en) | 2016-08-02 |
EP2958558A2 (en) | 2015-12-30 |
WO2014130619A3 (en) | 2014-10-16 |
HK1219884A1 (zh) | 2017-04-21 |
WO2014130619A2 (en) | 2014-08-28 |
JP6501123B2 (ja) | 2019-04-17 |
PL2958558T3 (pl) | 2018-12-31 |
AU2014218938A1 (en) | 2015-09-10 |
JP2016509058A (ja) | 2016-03-24 |
KR102054038B1 (ko) | 2019-12-09 |
KR20150120424A (ko) | 2015-10-27 |
CN108309961A (zh) | 2018-07-24 |
US20150025135A1 (en) | 2015-01-22 |
TW201446240A (zh) | 2014-12-16 |
EP2958558A4 (en) | 2016-08-10 |
TWI597061B (zh) | 2017-09-01 |
ES2687286T3 (es) | 2018-10-24 |
CN105246470A (zh) | 2016-01-13 |
HK1255453A1 (zh) | 2019-08-16 |
AU2014218938B2 (en) | 2018-12-06 |
CA2901745A1 (en) | 2014-08-28 |
DK2958558T3 (en) | 2018-09-24 |
EP2958558B1 (en) | 2018-06-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2450 DE 19-12-2017 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |