BR112017016932A2 - métodos e sistemas para projeto e análise de experimentos - Google Patents

métodos e sistemas para projeto e análise de experimentos

Info

Publication number
BR112017016932A2
BR112017016932A2 BR112017016932A BR112017016932A BR112017016932A2 BR 112017016932 A2 BR112017016932 A2 BR 112017016932A2 BR 112017016932 A BR112017016932 A BR 112017016932A BR 112017016932 A BR112017016932 A BR 112017016932A BR 112017016932 A2 BR112017016932 A2 BR 112017016932A2
Authority
BR
Brazil
Prior art keywords
amplification
amplification curves
curves
list
display screen
Prior art date
Application number
BR112017016932A
Other languages
English (en)
Other versions
BR112017016932B1 (pt
Inventor
Hoard David
Siong Teo Kok
Seng Loh Lian
Seng Lau Lik
Uy Michael
Rickes Scott
Zimmerman Sean
Pho Vanee
Wei Chu Zeng
Original Assignee
Life Technologies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Life Technologies Corp filed Critical Life Technologies Corp
Publication of BR112017016932A2 publication Critical patent/BR112017016932A2/pt
Publication of BR112017016932B1 publication Critical patent/BR112017016932B1/pt

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B45/00—ICT specially adapted for bioinformatics-related data visualisation, e.g. displaying of maps or networks
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F3/00—Input arrangements for transferring data to be processed into a form capable of being handled by the computer; Output arrangements for transferring data from processing unit to output unit, e.g. interface arrangements
    • G06F3/01—Input arrangements or combined input and output arrangements for interaction between user and computer
    • G06F3/048—Interaction techniques based on graphical user interfaces [GUI]
    • G06F3/0481—Interaction techniques based on graphical user interfaces [GUI] based on specific properties of the displayed interaction object or a metaphor-based environment, e.g. interaction with desktop elements like windows or icons, or assisted by a cursor's changing behaviour or appearance
    • G06F3/0482—Interaction with lists of selectable items, e.g. menus
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F3/00—Input arrangements for transferring data to be processed into a form capable of being handled by the computer; Output arrangements for transferring data from processing unit to output unit, e.g. interface arrangements
    • G06F3/01—Input arrangements or combined input and output arrangements for interaction between user and computer
    • G06F3/048—Interaction techniques based on graphical user interfaces [GUI]
    • G06F3/0484—Interaction techniques based on graphical user interfaces [GUI] for the control of specific functions or operations, e.g. selecting or manipulating an object, an image or a displayed text element, setting a parameter value or selecting a range
    • G06F3/04842—Selection of displayed objects or displayed text elements
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F3/00—Input arrangements for transferring data to be processed into a form capable of being handled by the computer; Output arrangements for transferring data from processing unit to output unit, e.g. interface arrangements
    • G06F3/01—Input arrangements or combined input and output arrangements for interaction between user and computer
    • G06F3/048—Interaction techniques based on graphical user interfaces [GUI]
    • G06F3/0484—Interaction techniques based on graphical user interfaces [GUI] for the control of specific functions or operations, e.g. selecting or manipulating an object, an image or a displayed text element, setting a parameter value or selecting a range
    • G06F3/0485—Scrolling or panning
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F3/00—Input arrangements for transferring data to be processed into a form capable of being handled by the computer; Output arrangements for transferring data from processing unit to output unit, e.g. interface arrangements
    • G06F3/01—Input arrangements or combined input and output arrangements for interaction between user and computer
    • G06F3/048—Interaction techniques based on graphical user interfaces [GUI]
    • G06F3/0487—Interaction techniques based on graphical user interfaces [GUI] using specific features provided by the input device, e.g. functions controlled by the rotation of a mouse with dual sensing arrangements, or of the nature of the input device, e.g. tap gestures based on pressure sensed by a digitiser
    • G06F3/0488—Interaction techniques based on graphical user interfaces [GUI] using specific features provided by the input device, e.g. functions controlled by the rotation of a mouse with dual sensing arrangements, or of the nature of the input device, e.g. tap gestures based on pressure sensed by a digitiser using a touch-screen or digitiser, e.g. input of commands through traced gestures
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T11/00—2D [Two Dimensional] image generation
    • G06T11/20—Drawing from basic elements, e.g. lines or circles
    • G06T11/206—Drawing of charts or graphs
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T3/00—Geometric image transformations in the plane of the image
    • G06T3/40—Scaling of whole images or parts thereof, e.g. expanding or contracting

Landscapes

  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Theoretical Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Human Computer Interaction (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Optics & Photonics (AREA)
  • Data Mining & Analysis (AREA)
  • Evolutionary Biology (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • User Interface Of Digital Computer (AREA)

Abstract

é fornecido um método para identificar um local de reação associado a uma curva de amplificação a partir de uma pluralidade de curvas de amplificação (104, 204, 304, 404). o método inclui receber dados de amplificação de uma pluralidade de locais de reação, em que cada local de reação contém uma amostra. o método inclui ainda a geração de uma pluralidade de curvas de amplificação (104, 204, 304, 404) a partir dos dados de amplificação e exibindo uma primeira porção da plurali-dade de curvas de amplificação (104, 204, 304, 404) numa tela de exibição (1212). o método inclui a exibição de uma lista de indicações de locais de reação (a24-a29) associados à primeira porção de curvas de amplificação (104, 204, 304, 404) ao lon-go da primeira porção de curvas de amplificação (104, 204, 304, 404) na tela de exi-bição (1212). em seguida, o método inclui o ajuste da vista para exibir uma segunda porção da pluralidade de curvas de amplificação (104, 204, 304, 404). o método in-clui ainda o ajuste dinâmico da lista para exibir indicações dos locais de reação (a24-a29) associados à segunda porção de curvas de amplificação (104, 204, 304, 404) ao lado da segunda porção de curvas de amplificação (104, 204, 304, 404) na tela de exibição (1212), em que a lista está configurada para ser deslocável.
BR112017016932-0A 2015-02-06 2016-02-05 método, sistema e mídia de armazenamento não transitório legível por computador para identificar um local de reação associado a uma curva de amplificação a partir de uma pluralidade de curvas de amplificação BR112017016932B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562113006P 2015-02-06 2015-02-06
US62/113,006 2015-02-06
PCT/US2016/016827 WO2016127086A1 (en) 2015-02-06 2016-02-05 Methods and systems for experiment design and analysis

Publications (2)

Publication Number Publication Date
BR112017016932A2 true BR112017016932A2 (pt) 2018-04-03
BR112017016932B1 BR112017016932B1 (pt) 2021-04-20

Family

ID=55411750

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017016932-0A BR112017016932B1 (pt) 2015-02-06 2016-02-05 método, sistema e mídia de armazenamento não transitório legível por computador para identificar um local de reação associado a uma curva de amplificação a partir de uma pluralidade de curvas de amplificação

Country Status (9)

Country Link
US (1) US10102653B2 (pt)
EP (1) EP3254086B1 (pt)
JP (1) JP6496417B2 (pt)
KR (1) KR102541746B1 (pt)
CN (1) CN107223249B (pt)
BR (1) BR112017016932B1 (pt)
RU (1) RU2719346C2 (pt)
SG (2) SG11201706356XA (pt)
WO (1) WO2016127086A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2019212931A1 (en) * 2018-01-29 2020-08-27 Gen-Probe Incorporated Analytical systems and methods
USD872109S1 (en) 2018-08-07 2020-01-07 Caterpillar Inc. Display screen or portion thereof with graphical user interface

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69919875T2 (de) * 1999-03-27 2005-09-15 Applera Corp., Foster City Methoden für exogene, interne kontrollen während der amplifizierung von nukleinsäuren
US6518068B1 (en) * 1999-07-21 2003-02-11 Tropix, Inc. Luminescence detection workstation
WO2003006692A1 (en) * 2001-07-11 2003-01-23 Applera Corporation Internal calibration standards for electrophoretic analyses
US7363168B2 (en) * 2001-10-02 2008-04-22 Stratagene California Adaptive baseline algorithm for quantitative PCR
US7315376B2 (en) * 2005-01-07 2008-01-01 Advanced Molecular Systems, Llc Fluorescence detection system
US7630849B2 (en) * 2005-09-01 2009-12-08 Applied Biosystems, Llc Method of automated calibration and diagnosis of laboratory instruments
US8473216B2 (en) * 2006-11-30 2013-06-25 Fluidigm Corporation Method and program for performing baseline correction of amplification curves in a PCR experiment
CN102395977B (zh) * 2009-04-16 2014-10-22 皇家飞利浦电子股份有限公司 核酸定量的方法
US8754890B2 (en) * 2009-07-31 2014-06-17 Oracle International Corporation Graphical interface with data presence indicators
CN103038773B (zh) * 2010-04-08 2016-06-08 生命技术公司 通过角度配置搜索的用于基因分型的系统和方法
JP5908886B2 (ja) * 2010-04-09 2016-04-26 ライフ テクノロジーズ コーポレーション ｑＰＣＲ遺伝子型決定データ用の視覚化ツール
SG184481A1 (en) * 2010-04-11 2012-11-29 Life Technologies Corp SYSTEMS AND METHODS FOR MODEL-BASED qPCR
WO2012024500A1 (en) * 2010-08-18 2012-02-23 Life Technologies Corporation Chemical coating of microwell for electrochemical detection device
US9422670B2 (en) * 2010-12-15 2016-08-23 Kemira Oyj Aqueous starch containing polymer dispersion for paper applications
JP2014507031A (ja) * 2011-02-01 2014-03-20 ライフ テクノロジーズ コーポレーション タンパク質融解曲線データの分析のためのシステムおよび方法
KR20120103496A (ko) * 2011-03-09 2012-09-19 삼성테크윈 주식회사 실시간 중합효소 연쇄 반응에 있어서 표준 곡선 및 임계값을 획득하는 방법
CN106407741A (zh) * 2011-09-30 2017-02-15 生命技术公司 用于可视化和评估数据的方法和系统
SG10201602113TA (en) * 2011-09-30 2016-04-28 Life Technologies Corp Systems And Methods For Biological Analysis

Also Published As

Publication number Publication date
RU2719346C2 (ru) 2020-04-17
JP6496417B2 (ja) 2019-04-03
SG11201706356XA (en) 2017-09-28
CN107223249B (zh) 2021-06-18
KR102541746B1 (ko) 2023-06-09
EP3254086A1 (en) 2017-12-13
US10102653B2 (en) 2018-10-16
JP2018506974A (ja) 2018-03-15
RU2017131044A (ru) 2019-03-06
US20160239990A1 (en) 2016-08-18
WO2016127086A1 (en) 2016-08-11
CN107223249A (zh) 2017-09-29
KR20170135832A (ko) 2017-12-08
SG10202006588UA (en) 2020-08-28
RU2017131044A3 (pt) 2019-07-17
EP3254086B1 (en) 2020-08-05
BR112017016932B1 (pt) 2021-04-20

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Legal Events

Date Code Title Description
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 05/02/2016, OBSERVADAS AS CONDICOES LEGAIS.