BR112017010832A2 - composições de aminoácido para o tratamento de sintomas de doença - Google Patents
composições de aminoácido para o tratamento de sintomas de doençaInfo
- Publication number
- BR112017010832A2 BR112017010832A2 BR112017010832A BR112017010832A BR112017010832A2 BR 112017010832 A2 BR112017010832 A2 BR 112017010832A2 BR 112017010832 A BR112017010832 A BR 112017010832A BR 112017010832 A BR112017010832 A BR 112017010832A BR 112017010832 A2 BR112017010832 A2 BR 112017010832A2
- Authority
- BR
- Brazil
- Prior art keywords
- amino acid
- disease symptoms
- acid compositions
- treating disease
- group
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 150000001413 amino acids Chemical class 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- 208000024891 symptom Diseases 0.000 title abstract 2
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 2
- DCXYFEDJOCDNAF-UHFFFAOYSA-N Asparagine Natural products OC(=O)C(N)CC(N)=O DCXYFEDJOCDNAF-UHFFFAOYSA-N 0.000 abstract 1
- 206010003591 Ataxia Diseases 0.000 abstract 1
- 206010012735 Diarrhoea Diseases 0.000 abstract 1
- 201000011001 Ebola Hemorrhagic Fever Diseases 0.000 abstract 1
- 239000004471 Glycine Substances 0.000 abstract 1
- 208000031886 HIV Infections Diseases 0.000 abstract 1
- 208000037357 HIV infectious disease Diseases 0.000 abstract 1
- 206010019133 Hangover Diseases 0.000 abstract 1
- DCXYFEDJOCDNAF-REOHCLBHSA-N L-asparagine Chemical compound OC(=O)[C@@H](N)CC(N)=O DCXYFEDJOCDNAF-REOHCLBHSA-N 0.000 abstract 1
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 abstract 1
- AGPKZVBTJJNPAG-WHFBIAKZSA-N L-isoleucine Chemical compound CC[C@H](C)[C@H](N)C(O)=O AGPKZVBTJJNPAG-WHFBIAKZSA-N 0.000 abstract 1
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 abstract 1
- AYFVYJQAPQTCCC-GBXIJSLDSA-N L-threonine Chemical compound C[C@@H](O)[C@H](N)C(O)=O AYFVYJQAPQTCCC-GBXIJSLDSA-N 0.000 abstract 1
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 abstract 1
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 abstract 1
- KZSNJWFQEVHDMF-BYPYZUCNSA-N L-valine Chemical compound CC(C)[C@H](N)C(O)=O KZSNJWFQEVHDMF-BYPYZUCNSA-N 0.000 abstract 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 abstract 1
- 239000004472 Lysine Substances 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 abstract 1
- 241000282898 Sus scrofa Species 0.000 abstract 1
- AYFVYJQAPQTCCC-UHFFFAOYSA-N Threonine Natural products CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 abstract 1
- 239000004473 Threonine Substances 0.000 abstract 1
- QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 abstract 1
- KZSNJWFQEVHDMF-UHFFFAOYSA-N Valine Natural products CC(C)C(N)C(O)=O KZSNJWFQEVHDMF-UHFFFAOYSA-N 0.000 abstract 1
- 229940024606 amino acid Drugs 0.000 abstract 1
- 235000001014 amino acid Nutrition 0.000 abstract 1
- 229960001230 asparagine Drugs 0.000 abstract 1
- 235000009582 asparagine Nutrition 0.000 abstract 1
- 235000003704 aspartic acid Nutrition 0.000 abstract 1
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 208000037902 enteropathy Diseases 0.000 abstract 1
- 230000007613 environmental effect Effects 0.000 abstract 1
- 208000033519 human immunodeficiency virus infectious disease Diseases 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 208000028774 intestinal disease Diseases 0.000 abstract 1
- 229960000310 isoleucine Drugs 0.000 abstract 1
- AGPKZVBTJJNPAG-UHFFFAOYSA-N isoleucine Natural products CCC(C)C(N)C(O)=O AGPKZVBTJJNPAG-UHFFFAOYSA-N 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 abstract 1
- 239000004474 valine Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Tropical Medicine & Parasitology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Molecular Biology (AREA)
- Rheumatology (AREA)
- AIDS & HIV (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
a presente invenção fornece composições terapêuticas e usos das mesmas para o tratamento ou melhora de sintomas de uma doença selecionada a partir do grupo que consiste em: infecção por vírus ebola, infecção por hiv, ataxia, enteropatia ambiental, câncer, ressaca, doença inflamatória e diarreia epidêmica suína. em modalidades preferenciais, a composição inclui uma combinação de um ou mais aminoácidos selecionados a partir do grupo que compreende lisina, ácido aspártico, glicina, isoleucina, treonina, tirosina, valina, triptofano, asparagina e/ou serina.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462083698P | 2014-11-24 | 2014-11-24 | |
US201562138051P | 2015-03-25 | 2015-03-25 | |
PCT/US2015/061462 WO2016085735A1 (en) | 2014-11-24 | 2015-11-19 | Amino acid compositions for the treatment of symptoms of disease |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112017010832A2 true BR112017010832A2 (pt) | 2017-12-26 |
Family
ID=56074902
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112017010832A BR112017010832A2 (pt) | 2014-11-24 | 2015-11-19 | composições de aminoácido para o tratamento de sintomas de doença |
Country Status (8)
Country | Link |
---|---|
US (4) | US20170326088A1 (pt) |
EP (3) | EP3616689A1 (pt) |
JP (1) | JP2017535591A (pt) |
CN (1) | CN107106527B (pt) |
BR (1) | BR112017010832A2 (pt) |
CA (1) | CA2968831A1 (pt) |
MX (1) | MX2017006748A (pt) |
WO (1) | WO2016085735A1 (pt) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA3135553C (en) * | 2016-10-04 | 2024-05-21 | University Of Florida Research Foundation, Incorporated | Amino acid compositions and uses thereof |
JP2019043861A (ja) * | 2017-08-30 | 2019-03-22 | アサヒグループホールディングス株式会社 | 乳酸/ピルビン酸比の改善用組成物 |
WO2019070753A1 (en) * | 2017-10-02 | 2019-04-11 | University Of Florida Research Foundation, Incorporated | AMINO ACID COMPOSITIONS AND METHODS FOR TREATING DIARRHEA |
US20210145797A1 (en) * | 2018-04-04 | 2021-05-20 | University Of Florida Research Foundation, Incorporated | Compositions for treating skin |
IT201800005599A1 (it) * | 2018-05-22 | 2019-11-22 | Lente a contatto morbida | |
CN108434304A (zh) * | 2018-05-23 | 2018-08-24 | 北京雄九医学研究院 | 防癌抗癌中药的制备方法 |
IL299488A (en) * | 2020-07-02 | 2023-02-01 | Univ Florida | Preparations for promoting hydration and methods of using them |
US11878073B1 (en) | 2022-09-20 | 2024-01-23 | Entrinsic, LLC | Generation of hydration-targeted formulations and methods of use therein |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3532204B2 (ja) | 1991-03-05 | 2004-05-31 | アラダイム コーポレーション | 流量計の圧力センサのドリフトオフセットを補正する方法および装置 |
ATE189124T1 (de) | 1991-07-02 | 2000-02-15 | Inhale Inc | Verfahren und vorrichtung zum abgeben von medikamenten in aerosolform |
US6582728B1 (en) | 1992-07-08 | 2003-06-24 | Inhale Therapeutic Systems, Inc. | Spray drying of macromolecules to produce inhaleable dry powders |
US5558085A (en) | 1993-01-29 | 1996-09-24 | Aradigm Corporation | Intrapulmonary delivery of peptide drugs |
US5934272A (en) | 1993-01-29 | 1999-08-10 | Aradigm Corporation | Device and method of creating aerosolized mist of respiratory drug |
US6051256A (en) | 1994-03-07 | 2000-04-18 | Inhale Therapeutic Systems | Dispersible macromolecule compositions and methods for their preparation and use |
KR19980702436A (ko) | 1995-02-23 | 1998-07-15 | 하인쯔 쉬나이더, 미첼 오르진거 | 아미노산 조성물 및 임상용 영양물내에 이의 사용 방법 |
WO1998029140A1 (en) | 1996-12-31 | 1998-07-09 | Inhale Therapeutic Systems | Processes and compositions for spray drying hydrophobic drugs in organic solvent suspensions of hydrophilic excipients |
CA2340468A1 (en) | 1998-11-13 | 2000-05-25 | Children's Hospital Of Los Angeles | Methods of facilitating vascular growth |
CA2397216C (en) | 2000-01-14 | 2011-07-12 | Baldur Hjaltason | Marine lipid composition for feeding aquatic organisms |
GB0009056D0 (en) | 2000-04-12 | 2000-05-31 | Nestle Sa | Composition comprising free amino acids |
US7063865B2 (en) * | 2002-05-10 | 2006-06-20 | Jeremy Park Jones | Composition and method for substantially reducing the deleterious effects of alcohol on the body |
US20040087490A1 (en) * | 2002-09-20 | 2004-05-06 | Troup John P. | Nutritional compositions |
US20070010459A1 (en) | 2005-01-14 | 2007-01-11 | Ying Liu | Application of asiatic acid and its derivatives to treat pulmonary fibrosis |
EP1864692A1 (en) | 2006-06-07 | 2007-12-12 | Biotempt B.V. | Use of peptides for the control of radiation injury |
US20110183040A1 (en) | 2007-08-03 | 2011-07-28 | Ermolin Gennady A | Amino Acid and Peptide Products |
IT1396935B1 (it) | 2009-11-26 | 2012-12-20 | Solartium Entpr Ltd | Uso di una combinazione per il trattamento delle mucositi indotte da radiazioni o da chemioterapici |
IT1397861B1 (it) * | 2010-01-27 | 2013-02-04 | Ambrosialab Srl | Metodo e composizioni per l'applicazione di aminoacidi sulla pelle mediante un mezzo anidro |
GB201012539D0 (en) | 2010-07-27 | 2010-09-08 | Savantium Ltd | Nutritional compositions |
CA2809489C (en) * | 2010-09-24 | 2017-10-24 | University Of Florida Research Foundation, Inc. | For improving health of subjects with villous atrophy |
SG193927A1 (en) * | 2011-04-12 | 2013-11-29 | Nestec Sa | Nutritional compositions including branched chain fatty acids for wound healing |
US20130156846A1 (en) * | 2011-11-21 | 2013-06-20 | The Institute For Ethnomedicine | L-serine compositions, methods and uses for treating neurodegenerative diseases and disorders |
CN104093410B (zh) * | 2012-02-08 | 2018-04-27 | 佛罗里达大学研究基金会有限公司 | 用于治疗腹泻的物质和方法 |
WO2014062683A1 (en) * | 2012-10-15 | 2014-04-24 | University Of Florida Research Foundation, Inc. | Materials and methods for prevention and treatment of diarrhea and inflammation in the gastrointestinal tract |
-
2015
- 2015-11-19 EP EP19200092.5A patent/EP3616689A1/en active Pending
- 2015-11-19 MX MX2017006748A patent/MX2017006748A/es unknown
- 2015-11-19 EP EP15863301.6A patent/EP3223809A4/en not_active Withdrawn
- 2015-11-19 CA CA2968831A patent/CA2968831A1/en not_active Abandoned
- 2015-11-19 BR BR112017010832A patent/BR112017010832A2/pt not_active Application Discontinuation
- 2015-11-19 CN CN201580070181.8A patent/CN107106527B/zh active Active
- 2015-11-19 WO PCT/US2015/061462 patent/WO2016085735A1/en active Application Filing
- 2015-11-19 EP EP18202832.4A patent/EP3459540A1/en not_active Withdrawn
- 2015-11-19 JP JP2017528851A patent/JP2017535591A/ja active Pending
- 2015-11-19 US US15/528,990 patent/US20170326088A1/en not_active Abandoned
-
2018
- 2018-06-05 US US16/000,792 patent/US10758506B2/en active Active
-
2020
- 2020-08-07 US US16/987,507 patent/US11357747B2/en active Active
-
2022
- 2022-06-10 US US17/837,666 patent/US20220347143A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
US20220347143A1 (en) | 2022-11-03 |
JP2017535591A (ja) | 2017-11-30 |
WO2016085735A1 (en) | 2016-06-02 |
US20180289648A1 (en) | 2018-10-11 |
CN107106527B (zh) | 2020-11-24 |
MX2017006748A (es) | 2017-08-28 |
EP3223809A4 (en) | 2018-08-15 |
CN107106527A (zh) | 2017-08-29 |
US10758506B2 (en) | 2020-09-01 |
US20200368194A1 (en) | 2020-11-26 |
EP3616689A1 (en) | 2020-03-04 |
US11357747B2 (en) | 2022-06-14 |
CA2968831A1 (en) | 2016-06-02 |
EP3459540A1 (en) | 2019-03-27 |
EP3223809A1 (en) | 2017-10-04 |
US20170326088A1 (en) | 2017-11-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B15I | Others concerning applications: loss of priority | ||
B151 | Others concerning applications: resolution cancelled [chapter 15.31 patent gazette] | ||
B25D | Requested change of name of applicant approved |
Owner name: ENTRINSIC HEALTH SOLUTIONS, INC. (US) |
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B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
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B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
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B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
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B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |