BR112017006201B1 - Oligonucleotídeo antisense e composição farmacêutica relatório - Google Patents

Oligonucleotídeo antisense e composição farmacêutica relatório Download PDF

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BR112017006201B1
BR112017006201B1 BR112017006201-1A BR112017006201A BR112017006201B1 BR 112017006201 B1 BR112017006201 B1 BR 112017006201B1 BR 112017006201 A BR112017006201 A BR 112017006201A BR 112017006201 B1 BR112017006201 B1 BR 112017006201B1
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seq
lna
nucleotides
antisense oligonucleotide
sequence
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BR112017006201-1A
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Portuguese (pt)
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BR112017006201A2 (pt
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Markus Hossbach
Monika KRAMPERT
Hans-Lothar ARTH
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Neurovision Pharma GmbH
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BR112017006201-1A 2014-11-16 2015-11-16 Oligonucleotídeo antisense e composição farmacêutica relatório BR112017006201B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14193368.9 2014-11-16
EP14193368.9A EP3020813A1 (en) 2014-11-16 2014-11-16 Antisense-oligonucleotides as inhibitors of TGF-R signaling
PCT/EP2015/076730 WO2016075339A1 (en) 2014-11-16 2015-11-16 Antisense-oligonucleotides as inhibitors of tgf-r signaling

Publications (2)

Publication Number Publication Date
BR112017006201A2 BR112017006201A2 (pt) 2018-05-02
BR112017006201B1 true BR112017006201B1 (pt) 2023-04-18

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BR112017006201-1A BR112017006201B1 (pt) 2014-11-16 2015-11-16 Oligonucleotídeo antisense e composição farmacêutica relatório

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US (4) US11213541B2 (https=)
EP (3) EP3020813A1 (https=)
JP (2) JP6832285B2 (https=)
KR (2) KR102417601B1 (https=)
CN (2) CN113151261B (https=)
AU (3) AU2015345006B2 (https=)
BR (1) BR112017006201B1 (https=)
CA (2) CA3201845C (https=)
CL (2) CL2017001233A1 (https=)
CY (1) CY1121110T1 (https=)
DK (1) DK3218488T3 (https=)
ES (1) ES2705066T3 (https=)
HU (1) HUE041793T2 (https=)
IL (2) IL251565B (https=)
MX (2) MX2017006369A (https=)
MY (1) MY181404A (https=)
PL (1) PL3218488T3 (https=)
PT (1) PT3218488T (https=)
RU (1) RU2717454C2 (https=)
SG (1) SG11201703127SA (https=)
TR (1) TR201900844T4 (https=)
WO (1) WO2016075339A1 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3020813A1 (en) * 2014-11-16 2016-05-18 Neurovision Pharma GmbH Antisense-oligonucleotides as inhibitors of TGF-R signaling
WO2019010226A1 (en) * 2017-07-03 2019-01-10 The Regents Of The University Of California CHEMICALLY MODIFIED MICROARN-214 ANTISENS AND USE THEREOF FOR THE TREATMENT OF HEMORRHAGIC RECTOCOLITE AND PROCTITE
BR112020008478A2 (pt) * 2017-11-01 2020-10-20 Editas Medicine, Inc. métodos, composições e componentes para edição de crispr-cas9 de tgfbr2 em células t para imunota-rapia
WO2019122279A1 (en) * 2017-12-22 2019-06-27 Roche Innovation Center Copenhagen A/S Oligonucleotides comprising a phosphorodithioate internucleoside linkage
WO2019122282A1 (en) * 2017-12-22 2019-06-27 Roche Innovation Center Copenhagen A/S Gapmer oligonucleotides comprising a phosphorodithioate internucleoside linkage
CN111448316B (zh) * 2017-12-22 2025-02-14 罗氏创新中心哥本哈根有限公司 新的硫代亚磷酰胺
MA53924A (fr) 2018-05-22 2021-08-25 Ionis Pharmaceuticals Inc Modulateurs de l'expression d'apol1
US20210292358A1 (en) * 2018-07-31 2021-09-23 Roche Innovation Center Copenhagen A/S Oligonucleotides comprising a phosphorotrithioate internucleoside linkage
EP3830101B1 (en) * 2018-07-31 2025-11-19 Roche Innovation Center Copenhagen A/S Oligonucleotides comprising a phosphorotrithioate internucleoside linkage
CA3130431A1 (en) * 2019-02-20 2020-08-27 Roche Innovation Center Copenhagen A/S Phosphonoacetate gapmer oligonucleotides
JP2023548597A (ja) * 2020-10-29 2023-11-17 エー． ガルシア－ブランコ，マリアーノ がんを処置するための可溶性インターロイキン－７受容体（ｓＩＬ７Ｒ）変調療法
CN114588160A (zh) * 2020-12-07 2022-06-07 四川大学华西医院 具有抗肺纤维化作用的次黄碱衍生物
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