BR112017005847A2 - métodos para produzir um composto de amida, para produzir um micro-organismo e para reduzir a formação de ácido acrílico, solução de composto de amida aquosa, composição, e, usos de uma nitrila hidratase e amidase e de um método de secagem. - Google Patents

métodos para produzir um composto de amida, para produzir um micro-organismo e para reduzir a formação de ácido acrílico, solução de composto de amida aquosa, composição, e, usos de uma nitrila hidratase e amidase e de um método de secagem.

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Publication number
BR112017005847A2
BR112017005847A2 BR112017005847A BR112017005847A BR112017005847A2 BR 112017005847 A2 BR112017005847 A2 BR 112017005847A2 BR 112017005847 A BR112017005847 A BR 112017005847A BR 112017005847 A BR112017005847 A BR 112017005847A BR 112017005847 A2 BR112017005847 A2 BR 112017005847A2
Authority
BR
Brazil
Prior art keywords
producing
amide compound
methods
amidase
microorganism
Prior art date
Application number
BR112017005847A
Other languages
English (en)
Inventor
Daeuwel Juergen
Baldenius Kai-Uwe
Kleiner Matthias
Braun Michael
Budde Michael
Oedman Peter
Freyer Stephan
Original Assignee
Basf Se
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Se filed Critical Basf Se
Publication of BR112017005847A2 publication Critical patent/BR112017005847A2/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P9/00—Preparation of organic compounds containing a metal or atom other than H, N, C, O, S or halogen
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/01—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
    • C12Y305/01004—Amidase (3.5.1.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/05—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in nitriles (3.5.5)
    • C12Y305/05001—Nitrilase (3.5.5.1)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Polyamides (AREA)

Abstract

a presente invenção refere-se a meios e métodos para produzir um composto de amida a partir de um composto de nitrila com menos ácido acrílico como subproduto usando uma nitrila hidratase (nhase) e amidase produzindo micro-organismo como biocatalisador. também é fornecido um composto de amida aquoso obtido através dos métodos da invenção bem como uma composição compreendendo acrilamida ou poliacrilamida bem como um micro-organismo seco exibindo uma razão de atividade nhase/amidase de pelo menos 400 quando colocado em contato com um composto de nitrila para converter o dito composto de nitrila em um composto de amida.
BR112017005847A 2014-09-30 2015-09-30 métodos para produzir um composto de amida, para produzir um micro-organismo e para reduzir a formação de ácido acrílico, solução de composto de amida aquosa, composição, e, usos de uma nitrila hidratase e amidase e de um método de secagem. BR112017005847A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14003378 2014-09-30
PCT/EP2015/072506 WO2016050816A2 (en) 2014-09-30 2015-09-30 Means and methods for producing amide compounds with less acrylic acid

Publications (1)

Publication Number Publication Date
BR112017005847A2 true BR112017005847A2 (pt) 2018-02-06

Family

ID=51661846

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017005847A BR112017005847A2 (pt) 2014-09-30 2015-09-30 métodos para produzir um composto de amida, para produzir um micro-organismo e para reduzir a formação de ácido acrílico, solução de composto de amida aquosa, composição, e, usos de uma nitrila hidratase e amidase e de um método de secagem.

Country Status (12)

Country Link
US (1) US10655152B2 (pt)
EP (1) EP3201349A2 (pt)
JP (1) JP7055633B2 (pt)
KR (1) KR20170061693A (pt)
CN (1) CN107075494B (pt)
AU (1) AU2015326905B2 (pt)
BR (1) BR112017005847A2 (pt)
CA (1) CA2962325A1 (pt)
CO (1) CO2017004034A2 (pt)
MY (1) MY191536A (pt)
RU (1) RU2730624C2 (pt)
WO (1) WO2016050816A2 (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10428361B2 (en) 2015-03-26 2019-10-01 Basf Se Biocatalytic production of l-fucose
WO2017055518A1 (en) * 2015-09-30 2017-04-06 Basf Se Means and methods for producing an amide compound
ITUA20163572A1 (it) * 2016-05-18 2017-11-18 Columbia S R L Metodo biotecnologico per la produzione di acrilammide e relativo nuovo ceppo batterico
CN107022497B (zh) * 2017-03-06 2019-09-20 江南大学 产腈水解酶的酵母菌株选育及其在腈类化合物生物转化中的应用
WO2019081318A1 (en) 2017-10-25 2019-05-02 Basf Se PROCESS FOR PRODUCING AQUEOUS POLYACRYLAMIDE SOLUTIONS
AR113386A1 (es) 2017-10-25 2020-04-29 Basf Se Proceso y planta modular y reubicable para producir soluciones acuosas de poliacrilamida
WO2019081004A1 (en) 2017-10-25 2019-05-02 Basf Se PROCESS FOR PRODUCING AQUEOUS POLYACRYLAMIDE SOLUTIONS
WO2019081003A1 (en) 2017-10-25 2019-05-02 Basf Se PROCESS FOR PRODUCING AQUEOUS POLYACRYLAMIDE SOLUTIONS
WO2019081008A1 (en) 2017-10-25 2019-05-02 Basf Se PROCESS FOR PRODUCING AQUEOUS ACRYLAMIDE SOLUTION
AR113377A1 (es) 2017-10-25 2020-04-22 Basf Se Proceso para producir soluciones acuosas de poliacrilamida
WO2019081323A1 (en) 2017-10-25 2019-05-02 Basf Se PROCESS FOR PRODUCING AQUEOUS POLYACRYLAMIDE SOLUTIONS
US11634516B2 (en) 2017-10-25 2023-04-25 Basf Se Process for producing aqueous polyacrylamide solutions
US11608468B2 (en) 2018-10-18 2023-03-21 Basf Se Process of fracturing subterranean formations
WO2020079124A1 (en) 2018-10-18 2020-04-23 Basf Se Process for producing aqueous polyacrylamide compositions
MX2021004420A (es) 2018-10-18 2021-07-06 Basf Se Proceso para producir un concentrado acuoso de poliacrilamida.
WO2020079119A1 (en) 2018-10-18 2020-04-23 Basf Se Method of providing aqueous polyacrylamide concentrates
CN109797164B (zh) * 2019-01-31 2022-09-02 大连理工大学 一种新型腈水合酶高效催化脂肪二腈水合反应的体系
CN111269848B (zh) * 2019-12-30 2022-03-18 浙江工业大学 赤红球菌jj-3及其在降解丙烯酸中的应用
CN111334495B (zh) * 2020-03-12 2022-04-29 宜昌东阳光生化制药有限公司 制备右旋酰胺酮洛芬的方法
WO2023041515A2 (en) 2021-09-15 2023-03-23 Basf Se Method for preparing an aqueous (meth) acrylamide solution

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4711955A (en) 1981-04-17 1987-12-08 Yale University Modified nucleotides and methods of preparing and using same
CA1223831A (en) 1982-06-23 1987-07-07 Dean Engelhardt Modified nucleotides, methods of preparing and utilizing and compositions containing the same
US5792608A (en) 1991-12-12 1998-08-11 Gilead Sciences, Inc. Nuclease stable and binding competent oligomers and methods for their use
RU2008589C1 (ru) 1992-05-14 1994-02-28 Сергей Николаевич Вирясов Способ контактной сушки микроорганизмов
RU2053300C1 (ru) * 1993-12-17 1996-01-27 Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов Штамм бактерий rhodococcus rhodochrous - продуцент нитрилгидратазы
US5525711A (en) 1994-05-18 1996-06-11 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Pteridine nucleotide analogs as fluorescent DNA probes
RU2288270C2 (ru) 2000-12-20 2006-11-27 Диа-Нитрикс Ко., Лтд. Способ производства амидного соединения с применением микробного катализатора
CN1806047A (zh) * 2003-06-10 2006-07-19 旭化成株式会社 新型腈水合酶
SG148992A1 (en) 2003-12-02 2009-01-29 Ciba Spec Chem Water Treat Ltd Strain of rhodococcus rhodochrous ncimb 41164 and its use as producer of nitrile hydratase
GB0327907D0 (en) * 2003-12-02 2004-01-07 Ciba Spec Chem Water Treat Ltd Microorganism
EP1689875B2 (en) * 2003-12-02 2017-02-22 Ciba Specialty Chemicals Water Treatments Limited Manufacture of amides
RU2304165C1 (ru) 2006-03-02 2007-08-10 Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов" (ФГУП ГосНИИгенетика) Способ получения акриловых мономеров и штамм бактерий rhodococcus rhodochrous для его осуществления
US8518685B2 (en) 2008-03-24 2013-08-27 Tsinghua University Engineered nitrile hydratase-producing bacterium with amidase gene knocked-out, the construction and the use thereof
JP2013517777A (ja) 2010-01-25 2013-05-20 ジョージア ステイト ユニヴァーシティー リサーチ ファウンデーション インコーポレイテッド 微生物における酵素活性の誘導および安定化

Also Published As

Publication number Publication date
KR20170061693A (ko) 2017-06-05
WO2016050816A3 (en) 2016-06-02
CA2962325A1 (en) 2016-04-07
AU2015326905B2 (en) 2019-07-04
EP3201349A2 (en) 2017-08-09
WO2016050816A2 (en) 2016-04-07
RU2017114400A (ru) 2018-11-02
CN107075494A (zh) 2017-08-18
JP7055633B2 (ja) 2022-04-18
RU2017114400A3 (pt) 2019-05-06
RU2730624C2 (ru) 2020-08-24
JP2017529847A (ja) 2017-10-12
CO2017004034A2 (es) 2017-09-20
MY191536A (en) 2022-06-29
AU2015326905A1 (en) 2017-04-06
US10655152B2 (en) 2020-05-19
CN107075494B (zh) 2021-11-23
US20170247726A1 (en) 2017-08-31

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Legal Events

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B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B11D Dismissal acc. art. 38, par 2 of ipl - failure to pay fee after grant in time