EA201791911A1 - Применение трихотецен-превращающей алкогольдегидрогеназы, способ превращения трихотеценов и трихотецен-превращающая добавка - Google Patents

Применение трихотецен-превращающей алкогольдегидрогеназы, способ превращения трихотеценов и трихотецен-превращающая добавка

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Publication number
EA201791911A1
EA201791911A1 EA201791911A EA201791911A EA201791911A1 EA 201791911 A1 EA201791911 A1 EA 201791911A1 EA 201791911 A EA201791911 A EA 201791911A EA 201791911 A EA201791911 A EA 201791911A EA 201791911 A1 EA201791911 A1 EA 201791911A1
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EA
Eurasian Patent Office
Prior art keywords
turning
additive
triothotocene
triothotocen
trihotocene
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EA201791911A
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English (en)
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EA036664B1 (ru
Inventor
Ева-Мария Биндер
Барбара Вебер
Клаудиа Бернард
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Эрбер Акциенгезелльшафт
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Publication of EA201791911A1 publication Critical patent/EA201791911A1/ru
Publication of EA036664B1 publication Critical patent/EA036664B1/ru

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/14—Pretreatment of feeding-stuffs with enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/60—Feeding-stuffs specially adapted for particular animals for weanlings
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/80—Feeding-stuffs specially adapted for particular animals for aquatic animals, e.g. fish, crustaceans or molluscs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44—Oxidoreductases (1)
    • A61K38/443—Oxidoreductases (1) acting on CH-OH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01001—Alcohol dehydrogenase (1.1.1.1)

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Polymers & Plastics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • Animal Husbandry (AREA)
  • Medicinal Chemistry (AREA)
  • Birds (AREA)
  • Physiology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Insects & Arthropods (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Fodder In General (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • General Preparation And Processing Of Foods (AREA)

Abstract

Применение алкогольдегидрогеназы с последовательностью, имеющей ID № 1, содержащей ионы металла и хиноновый кофактор, или в дополнение, функционального варианта, проявляющего идентичность последовательности, равную по меньшей мере 80%, предпочтительно по меньшей мере 86%, особенно предпочтительно по меньшей мере 89%, и по меньшей мере одного окислительно-восстановительного кофактора для превращения по меньшей мере одного трихотецена, имеющего гидроксильную группу на атоме С-3, а также способ ферментативного превращения трихотеценов и трихотецен-превращающая добавка.
EA201791911A 2015-03-27 2015-03-27 Применение трихотецен-превращающей алкогольдегидрогеназы, способ превращения трихотеценов и трихотецен-превращающая добавка EA036664B1 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/AT2015/000048 WO2016154640A1 (de) 2015-03-27 2015-03-27 Verwendung einer trichothecene transformierenden alkoholdehydrogenase, verfahren zur transformation von trichothecenen sowie trichothecene transformierender zusatzstoff

Publications (2)

Publication Number Publication Date
EA201791911A1 true EA201791911A1 (ru) 2018-02-28
EA036664B1 EA036664B1 (ru) 2020-12-07

Family

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Application Number Title Priority Date Filing Date
EA201791911A EA036664B1 (ru) 2015-03-27 2015-03-27 Применение трихотецен-превращающей алкогольдегидрогеназы, способ превращения трихотеценов и трихотецен-превращающая добавка

Country Status (13)

Country Link
US (2) US10526585B2 (ru)
EP (1) EP3273802A1 (ru)
JP (1) JP6646680B2 (ru)
CN (1) CN107109375A (ru)
AR (1) AR104043A1 (ru)
AU (1) AU2015388744B2 (ru)
CA (1) CA2979288C (ru)
EA (1) EA036664B1 (ru)
MY (1) MY187073A (ru)
SG (1) SG11201707010WA (ru)
UA (1) UA119813C2 (ru)
UY (1) UY36590A (ru)
WO (1) WO2016154640A1 (ru)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019046954A1 (en) * 2017-09-08 2019-03-14 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Agriculture And Agri-Food ENZYMATIC METHOD FOR THE DETOXICATION OF MYCOTOXINS
CN107916266B (zh) * 2017-12-05 2020-08-11 华中农业大学 镰刀菌毒素脱毒路径相关基因adh、akr6d1、akr13b2及其应用
TW202122578A (zh) 2019-08-30 2021-06-16 奧地利商爾伯股份有限公司 將基質3-酮-脫氧雪腐鐮刀菌烯醇轉化爲3-epi-脫氧雪腐鐮刀菌烯醇的改良多肽
US20210403841A1 (en) 2020-03-12 2021-12-30 Poet Research, Inc. Enzymatic degradation of mycotoxins during grain processing
WO2021249980A1 (en) 2020-06-08 2021-12-16 Erber Aktiengesellschaft Improved polypeptides capable of converting substrate 3-keto- deoxynivalenol into 3-epi-deoxynivalenol
EP3922726A1 (en) 2020-06-10 2021-12-15 Erber Aktiengesellschaft Truncated promoter for recombinant gene expression
EP3977863A1 (en) 2020-09-30 2022-04-06 Erber Aktiengesellschaft Means and methods to detoxify mycotoxins
US20230399674A1 (en) 2020-10-22 2023-12-14 Erber Aktiengesellschaft Methods and compositions for degrading deoxynivalenol
WO2023017146A1 (en) 2021-08-13 2023-02-16 DSM Austria GmbH Biomarker for trichothecene toxicity

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK13491D0 (da) 1991-01-25 1991-01-25 Novo Nordisk As Anvendelse af et enzymholdigt granulat og fremgangsmaade til fremstilling af et forderstof i tabletform
AT406166B (de) * 1997-12-30 2000-03-27 Erber Erich Kg Mikroorganismus, verfahren zur gewinnung desselben sowie futtermittelzusatz
JP2000032985A (ja) * 1998-07-15 2000-02-02 Inst Of Physical & Chemical Res トリコテセン ３−ｏ−アセチルトランスフェラーゼ遺伝子
JP2003159079A (ja) 2001-11-29 2003-06-03 Fujisawa Pharmaceut Co Ltd アルコール／アルデヒドデヒドロゲナーゼ、その製造方法およびその用途
JP2006117588A (ja) * 2004-10-22 2006-05-11 Shinhan Sha 生薬組成物
WO2009133462A2 (en) * 2008-04-30 2009-11-05 Danisco A/S Proteins
AR073602A1 (es) * 2008-09-18 2010-11-17 Erber Ag Metodo para producir un aditivo para la degradacion enzimatica de micotoxinas y aditivo y uso del mismo
WO2011041896A1 (en) * 2009-10-06 2011-04-14 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Agriculture And Agri-Food Bacterial isolate, methods of isolating bacterial isolates and methods for detoxification of trichothecene mycotoxins
EP2994536B1 (en) * 2013-05-08 2017-06-14 Roche Diabetes Care GmbH Stabilization of enzymes by nicotinic acid

Also Published As

Publication number Publication date
US20180080011A1 (en) 2018-03-22
SG11201707010WA (en) 2017-10-30
EA036664B1 (ru) 2020-12-07
UY36590A (es) 2016-09-30
UA119813C2 (uk) 2019-08-12
EP3273802A1 (de) 2018-01-31
CN107109375A (zh) 2017-08-29
CA2979288C (en) 2023-03-28
WO2016154640A8 (de) 2017-06-15
BR112017018606A2 (pt) 2018-04-17
JP2018509173A (ja) 2018-04-05
JP6646680B2 (ja) 2020-02-14
AU2015388744B2 (en) 2021-03-18
US20200010812A1 (en) 2020-01-09
MY187073A (en) 2021-08-29
CA2979288A1 (en) 2016-10-06
US11001812B2 (en) 2021-05-11
AR104043A1 (es) 2017-06-21
US10526585B2 (en) 2020-01-07
AU2015388744A1 (en) 2018-02-01
WO2016154640A1 (de) 2016-10-06

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