BR112017002003A2 - biomarcadores de doença renal policística e usos dos mesmos - Google Patents
biomarcadores de doença renal policística e usos dos mesmosInfo
- Publication number
- BR112017002003A2 BR112017002003A2 BR112017002003A BR112017002003A BR112017002003A2 BR 112017002003 A2 BR112017002003 A2 BR 112017002003A2 BR 112017002003 A BR112017002003 A BR 112017002003A BR 112017002003 A BR112017002003 A BR 112017002003A BR 112017002003 A2 BR112017002003 A2 BR 112017002003A2
- Authority
- BR
- Brazil
- Prior art keywords
- protein
- drp
- patient
- kinase
- phosphorylated
- Prior art date
Links
- 208000030761 polycystic kidney disease Diseases 0.000 title abstract 2
- 239000000090 biomarker Substances 0.000 title 1
- 108050006400 Cyclin Proteins 0.000 abstract 2
- 102000016736 Cyclin Human genes 0.000 abstract 2
- 102000007665 Extracellular Signal-Regulated MAP Kinases Human genes 0.000 abstract 2
- 108010007457 Extracellular Signal-Regulated MAP Kinases Proteins 0.000 abstract 2
- 108091008611 Protein Kinase B Proteins 0.000 abstract 2
- 102000005765 Proto-Oncogene Proteins c-akt Human genes 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 102000004046 Caspase-2 Human genes 0.000 abstract 1
- 108090000552 Caspase-2 Proteins 0.000 abstract 1
- 102000004232 Mitogen-Activated Protein Kinase Kinases Human genes 0.000 abstract 1
- 108090000744 Mitogen-Activated Protein Kinase Kinases Proteins 0.000 abstract 1
- 108010051791 Nuclear Antigens Proteins 0.000 abstract 1
- 102000019040 Nuclear Antigens Human genes 0.000 abstract 1
- 101150008755 PCNA gene Proteins 0.000 abstract 1
- 201000000582 Retinoblastoma Diseases 0.000 abstract 1
- 102000003861 Ribosomal protein S6 Human genes 0.000 abstract 1
- 108090000221 Ribosomal protein S6 Proteins 0.000 abstract 1
- 230000004663 cell proliferation Effects 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- 108091005981 phosphorylated proteins Proteins 0.000 abstract 1
- 210000003705 ribosome Anatomy 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/492—Determining multiple analytes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/34—Genitourinary disorders
- G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/56—Staging of a disease; Further complications associated with the disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Ecology (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462033031P | 2014-08-04 | 2014-08-04 | |
| PCT/US2015/043497 WO2016022500A2 (en) | 2014-08-04 | 2015-08-03 | Biomarkers of polycystic kidney disease and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112017002003A2 true BR112017002003A2 (pt) | 2017-12-12 |
Family
ID=54035292
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112017002003A BR112017002003A2 (pt) | 2014-08-04 | 2015-08-03 | biomarcadores de doença renal policística e usos dos mesmos |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US10871495B2 (enExample) |
| EP (1) | EP3177932B1 (enExample) |
| JP (2) | JP6730252B2 (enExample) |
| KR (1) | KR20170033436A (enExample) |
| CN (1) | CN106716136B (enExample) |
| AU (1) | AU2015301278A1 (enExample) |
| BR (1) | BR112017002003A2 (enExample) |
| CO (1) | CO2017001596A2 (enExample) |
| MX (1) | MX2017001648A (enExample) |
| RU (1) | RU2017106891A (enExample) |
| SG (1) | SG11201700290SA (enExample) |
| WO (1) | WO2016022500A2 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108700594B (zh) | 2015-11-18 | 2021-06-29 | 建新公司 | 多囊性肾病的生物标志物及其用途 |
| GB201719520D0 (en) * | 2017-11-24 | 2018-01-10 | Univ College Cardiff Consultants Ltd | Neuroprotectvie peptide |
| KR102859441B1 (ko) * | 2019-11-22 | 2025-09-12 | 서울대학교산학협력단 | Opn 검출용 제제를 포함하는, 다낭신의 진단용 조성물 및 이의 이용 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2374499A1 (en) | 1999-05-24 | 2000-11-30 | Avi Biopharma, Inc. | Antisense to c-myc for treatment of polycystic kidney disease |
| US9006181B2 (en) | 2004-07-21 | 2015-04-14 | The Administrators Of The Tulane Educational Fund | Treatment of renal dysfunction and multiple myeloma using PACAP compounds |
| EP1808694A1 (en) | 2006-01-17 | 2007-07-18 | Universitätsklinikum Freiburg | Method for diagnosing polycystic kidney disease |
| WO2010141862A2 (en) | 2009-06-05 | 2010-12-09 | Mayo Foundation For Medical Education And Research | Methods and materials for isolating exosomes |
| CN102018702B (zh) | 2009-09-16 | 2012-07-18 | 北京大学 | 银杏内酯b的一种用途 |
| US20140079769A1 (en) * | 2010-10-01 | 2014-03-20 | Fabiola Terzi | Methods for predicting the progression and treating a chronic kidney disease in a patient |
| US20130276513A1 (en) * | 2010-10-14 | 2013-10-24 | The Regents Of The University Of California | Methods for diagnosing and assessing kidney disease |
| US10478446B2 (en) | 2012-07-03 | 2019-11-19 | Fondazione Centro San Raffaele Office Of Biotechnology Transfer | Compounds for use in polycystic kidney disease |
| MA37975B2 (fr) * | 2012-09-11 | 2021-03-31 | Genzyme Corp | Inhibiteurs de synthase de glucosylcéramide |
-
2015
- 2015-08-03 SG SG11201700290SA patent/SG11201700290SA/en unknown
- 2015-08-03 WO PCT/US2015/043497 patent/WO2016022500A2/en not_active Ceased
- 2015-08-03 JP JP2017506291A patent/JP6730252B2/ja active Active
- 2015-08-03 AU AU2015301278A patent/AU2015301278A1/en not_active Abandoned
- 2015-08-03 MX MX2017001648A patent/MX2017001648A/es unknown
- 2015-08-03 US US15/501,496 patent/US10871495B2/en active Active
- 2015-08-03 BR BR112017002003A patent/BR112017002003A2/pt not_active Application Discontinuation
- 2015-08-03 KR KR1020177005740A patent/KR20170033436A/ko not_active Withdrawn
- 2015-08-03 EP EP15757363.5A patent/EP3177932B1/en active Active
- 2015-08-03 RU RU2017106891A patent/RU2017106891A/ru not_active Application Discontinuation
- 2015-08-03 CN CN201580053081.4A patent/CN106716136B/zh active Active
-
2017
- 2017-02-17 CO CONC2017/0001596A patent/CO2017001596A2/es unknown
-
2020
- 2020-07-01 JP JP2020113693A patent/JP7005695B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US10871495B2 (en) | 2020-12-22 |
| RU2017106891A (ru) | 2018-09-06 |
| RU2017106891A3 (enExample) | 2019-03-14 |
| JP2017525955A (ja) | 2017-09-07 |
| JP7005695B2 (ja) | 2022-02-04 |
| CN106716136A (zh) | 2017-05-24 |
| EP3177932B1 (en) | 2021-07-14 |
| KR20170033436A (ko) | 2017-03-24 |
| WO2016022500A3 (en) | 2016-04-07 |
| WO2016022500A2 (en) | 2016-02-11 |
| CN106716136B (zh) | 2020-06-23 |
| AU2015301278A1 (en) | 2017-02-09 |
| MX2017001648A (es) | 2017-04-27 |
| SG11201700290SA (en) | 2017-02-27 |
| EP3177932A2 (en) | 2017-06-14 |
| JP6730252B2 (ja) | 2020-07-29 |
| US20170227551A1 (en) | 2017-08-10 |
| JP2020170013A (ja) | 2020-10-15 |
| CO2017001596A2 (es) | 2017-05-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CO2019006485A2 (es) | Anticuerpos y metodos de su utilizacion | |
| BR112012009284A2 (pt) | método e sistema para avaliar automaticamente a semelhança entre uma região geológica alvo de interesse e uma pluralidade de regiões geológicas conhecidas de interesse. | |
| EP4614155A3 (en) | Methods of assaying proteins | |
| BR112016007348A2 (pt) | membro de ligação específica que se liga ao receptor do fator de crescimento epidérmico humano 2 (her2) para uso em um método de tratamento do câncer em um paciente, método de tratamento de câncer em um paciente, método de identificação de um câncer em um paciente, método para prognosticar a resposta de um câncer | |
| BR112015023262A2 (pt) | anticorpo isolado, ácido nucleico isolado, célula hospedeira, método para produzir um anticorpo, imunoconjugado, formulação farmacêutica e usos do anticorpo | |
| BR112014026990A2 (pt) | anticorpo , ácido nucleico , vetores , célula hospedeira , composição farmacêutica , uso de um anticorpo e método para o tratamento de um paciente com necessidade de terapia. | |
| BR112016016937A8 (pt) | partícula semelhante a vírus ou vírus, pluralidade de vírus isolados ou partículas semelhantes a vírus isoladas, ácido nucleico recombinante, célula adaptada a suspensão isolada, porção ligada a membrana da célula, célula adaptada a suspensão isolada, pluralidade de células adaptadas a suspensão isoladas, e método de identificação de um epítopo de célula t | |
| BR112014018970A8 (pt) | Dispositivos de coleta de amostra com agentes de estabilização sanguínea | |
| BR112016004324A2 (pt) | anticorpos | |
| BR112017023131A2 (pt) | anticorpos anti- fcrn | |
| WO2016015058A3 (en) | Methods of determining tissues and/or cell types giving rise to cell-free dna, and methods of identifying a disease or disorder using same | |
| BR112018008799A2 (pt) | método de prognóstico | |
| BR112016019836A2 (pt) | método para analisar uma amostra de um sujeito, dispositivo de diagnóstico para utilização no diagnóstico da endometriose, kit, uso de um biomarcador, e, método para aumentar uma resposta de anticorpos em um sujeito | |
| CL2016002004A1 (es) | Anticuerpos anti-jagged1 y métodos de uso | |
| BR112014018729A8 (pt) | Método e aparelho para testar materiais de circulação perdidos para formações subterrâneas | |
| MX2016011059A (es) | Sistemas, dispositivos y metodos para verificacion de la integridad de muestras. | |
| BR112015002634A2 (pt) | matriz e sistema para preservar espécimes biológicos para análise qualitativa e quantitativa. | |
| MX2024011859A (es) | Biomarcadores de arn para angioedema hereditario | |
| BR112016021679A2 (pt) | proteína de ligação ao antígeno, métodos de produção de uma proteína de ligação ao antígeno e de identificação de uma ou mais proteínas de ligação ao antígeno, hibridoma, ácido nucleico, célula, e, animal não humano geneticamente modificado. | |
| BR112019021352A8 (pt) | Método para determinar e mitigar o risco de formação de cera de uma composição de hidrocarboneto, método para reduzir os riscos de formação de cera e sistema para uso de análise preditiva no gerenciamento de um processamento de hidrocarbonetos para determinar e mitigar a formação de cera | |
| HK1244534A1 (zh) | 重组疏螺旋体蛋白及其使用方法 | |
| BR112016024457A2 (pt) | anticorpo isolado, imunoconjugado, uso do anticorpo, formulação farmacêutica, ácido nucleico isolado, célula hospedeira e método de produção de um anticorpo | |
| CO2017001596A2 (es) | Biomarcadores de enfermedad poliquística renal y usos de los mismos | |
| BR112018009879A2 (pt) | biomarcador da doença renal policística e seus usos | |
| BR112016024742A2 (pt) | método para a seleção de uma proteína, proteínas de ligação ao antígeno, anticorpos, imunoconjugado, formulação farmacêutica, uso do anticorpo, ácido nucleico e polipeptídeo |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements | ||
| B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
| B350 | Update of information on the portal [chapter 15.35 patent gazette] |