BR112017000449B1 - Processo de fermentação - Google Patents
Processo de fermentação Download PDFInfo
- Publication number
- BR112017000449B1 BR112017000449B1 BR112017000449-6A BR112017000449A BR112017000449B1 BR 112017000449 B1 BR112017000449 B1 BR 112017000449B1 BR 112017000449 A BR112017000449 A BR 112017000449A BR 112017000449 B1 BR112017000449 B1 BR 112017000449B1
- Authority
- BR
- Brazil
- Prior art keywords
- concentration
- culture medium
- flow rate
- measured
- bacteria
- Prior art date
Links
- 238000000855 fermentation Methods 0.000 title claims description 15
- 230000004151 fermentation Effects 0.000 title claims description 14
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 136
- 238000000034 method Methods 0.000 claims abstract description 122
- 239000001963 growth medium Substances 0.000 claims abstract description 112
- 230000008569 process Effects 0.000 claims abstract description 75
- 239000000047 product Substances 0.000 claims abstract description 24
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Natural products CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 133
- 229910002091 carbon monoxide Inorganic materials 0.000 claims description 127
- 241000894006 Bacteria Species 0.000 claims description 89
- 239000000758 substrate Substances 0.000 claims description 89
- 239000002207 metabolite Substances 0.000 claims description 78
- 239000002253 acid Substances 0.000 claims description 55
- 239000003795 chemical substances by application Substances 0.000 claims description 54
- 230000003472 neutralizing effect Effects 0.000 claims description 52
- 238000004519 manufacturing process Methods 0.000 claims description 34
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical group [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 claims description 19
- 239000003085 diluting agent Substances 0.000 claims description 18
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims description 17
- 239000000908 ammonium hydroxide Substances 0.000 claims description 14
- 230000007423 decrease Effects 0.000 claims description 11
- 239000012467 final product Substances 0.000 claims description 11
- 239000007788 liquid Substances 0.000 claims description 10
- 229910000831 Steel Inorganic materials 0.000 claims description 6
- 239000010959 steel Substances 0.000 claims description 6
- 238000002309 gasification Methods 0.000 claims description 5
- 239000003245 coal Substances 0.000 claims description 4
- CWYNVVGOOAEACU-UHFFFAOYSA-N Fe2+ Chemical compound [Fe+2] CWYNVVGOOAEACU-UHFFFAOYSA-N 0.000 claims description 3
- 229930195733 hydrocarbon Natural products 0.000 claims description 3
- 150000002430 hydrocarbons Chemical class 0.000 claims description 3
- 239000005416 organic matter Substances 0.000 claims description 3
- 238000000629 steam reforming Methods 0.000 claims description 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims 6
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 claims 4
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 claims 2
- 229910021529 ammonia Inorganic materials 0.000 claims 2
- 239000002551 biofuel Substances 0.000 claims 2
- 239000006229 carbon black Substances 0.000 claims 2
- 239000002609 medium Substances 0.000 claims 2
- 235000015097 nutrients Nutrition 0.000 claims 2
- 238000005504 petroleum refining Methods 0.000 claims 2
- 230000012010 growth Effects 0.000 abstract description 21
- 230000001580 bacterial effect Effects 0.000 abstract description 20
- 238000006243 chemical reaction Methods 0.000 abstract description 19
- 239000007795 chemical reaction product Substances 0.000 abstract description 14
- 230000000977 initiatory effect Effects 0.000 abstract description 11
- 230000002829 reductive effect Effects 0.000 abstract description 8
- 238000004590 computer program Methods 0.000 abstract description 7
- UGFAIRIUMAVXCW-UHFFFAOYSA-N Carbon monoxide Chemical compound [O+]#[C-] UGFAIRIUMAVXCW-UHFFFAOYSA-N 0.000 description 125
- 239000000523 sample Substances 0.000 description 46
- 235000011114 ammonium hydroxide Nutrition 0.000 description 17
- 238000005070 sampling Methods 0.000 description 17
- 230000031018 biological processes and functions Effects 0.000 description 16
- 239000007789 gas Substances 0.000 description 15
- 238000004458 analytical method Methods 0.000 description 14
- 230000004907 flux Effects 0.000 description 14
- 239000002028 Biomass Substances 0.000 description 11
- 210000004027 cell Anatomy 0.000 description 11
- 230000015572 biosynthetic process Effects 0.000 description 10
- 230000000813 microbial effect Effects 0.000 description 10
- 238000004128 high performance liquid chromatography Methods 0.000 description 9
- 238000005259 measurement Methods 0.000 description 9
- 239000000446 fuel Substances 0.000 description 7
- 239000012466 permeate Substances 0.000 description 7
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 6
- 230000002378 acidificating effect Effects 0.000 description 6
- 229910052799 carbon Inorganic materials 0.000 description 6
- 239000000356 contaminant Substances 0.000 description 6
- 230000003247 decreasing effect Effects 0.000 description 6
- 239000012528 membrane Substances 0.000 description 6
- VNWKTOKETHGBQD-UHFFFAOYSA-N methane Chemical compound C VNWKTOKETHGBQD-UHFFFAOYSA-N 0.000 description 6
- 230000008901 benefit Effects 0.000 description 5
- 230000004044 response Effects 0.000 description 5
- 238000003786 synthesis reaction Methods 0.000 description 5
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 4
- ZSLZBFCDCINBPY-ZSJPKINUSA-N acetyl-CoA Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)C)O[C@H]1N1C2=NC=NC(N)=C2N=C1 ZSLZBFCDCINBPY-ZSJPKINUSA-N 0.000 description 4
- 239000006227 byproduct Substances 0.000 description 4
- 230000000052 comparative effect Effects 0.000 description 4
- 238000001914 filtration Methods 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 238000000926 separation method Methods 0.000 description 4
- 239000002699 waste material Substances 0.000 description 4
- 229920002472 Starch Polymers 0.000 description 3
- 229930006000 Sucrose Natural products 0.000 description 3
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 3
- 239000006143 cell culture medium Substances 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 238000000605 extraction Methods 0.000 description 3
- 230000002349 favourable effect Effects 0.000 description 3
- 235000013305 food Nutrition 0.000 description 3
- 238000012417 linear regression Methods 0.000 description 3
- 238000009629 microbiological culture Methods 0.000 description 3
- 244000005700 microbiome Species 0.000 description 3
- 239000003921 oil Substances 0.000 description 3
- 238000009428 plumbing Methods 0.000 description 3
- 235000019698 starch Nutrition 0.000 description 3
- 239000008107 starch Substances 0.000 description 3
- 229960004793 sucrose Drugs 0.000 description 3
- 230000007704 transition Effects 0.000 description 3
- 241001112696 Clostridia Species 0.000 description 2
- 241001656809 Clostridium autoethanogenum Species 0.000 description 2
- 241000205276 Methanosarcina Species 0.000 description 2
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 2
- ATUOYWHBWRKTHZ-UHFFFAOYSA-N Propane Chemical compound CCC ATUOYWHBWRKTHZ-UHFFFAOYSA-N 0.000 description 2
- 230000008238 biochemical pathway Effects 0.000 description 2
- 235000014633 carbohydrates Nutrition 0.000 description 2
- 150000001720 carbohydrates Chemical class 0.000 description 2
- 108010031234 carbon monoxide dehydrogenase Proteins 0.000 description 2
- 238000005119 centrifugation Methods 0.000 description 2
- 238000002485 combustion reaction Methods 0.000 description 2
- 238000010924 continuous production Methods 0.000 description 2
- 230000001419 dependent effect Effects 0.000 description 2
- 230000001627 detrimental effect Effects 0.000 description 2
- 239000000706 filtrate Substances 0.000 description 2
- 239000012737 fresh medium Substances 0.000 description 2
- 239000003502 gasoline Substances 0.000 description 2
- 239000005431 greenhouse gas Substances 0.000 description 2
- 239000001257 hydrogen Substances 0.000 description 2
- 229910052739 hydrogen Inorganic materials 0.000 description 2
- 239000012535 impurity Substances 0.000 description 2
- 238000011081 inoculation Methods 0.000 description 2
- -1 ion acetate Chemical class 0.000 description 2
- 238000012544 monitoring process Methods 0.000 description 2
- 229910052757 nitrogen Inorganic materials 0.000 description 2
- 230000001706 oxygenating effect Effects 0.000 description 2
- 230000037361 pathway Effects 0.000 description 2
- 239000002006 petroleum coke Substances 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 239000005720 sucrose Substances 0.000 description 2
- 235000000346 sugar Nutrition 0.000 description 2
- 241001148471 unidentified anaerobic bacterium Species 0.000 description 2
- 239000002912 waste gas Substances 0.000 description 2
- 241001468161 Acetobacterium Species 0.000 description 1
- QTXZASLUYMRUAN-QLQASOTGSA-N Acetyl coenzyme A (Acetyl-CoA) Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)C)O[C@H]1N1C2=NC=NC(N)=C2N=C1.O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)C)O[C@H]1N1C2=NC=NC(N)=C2N=C1 QTXZASLUYMRUAN-QLQASOTGSA-N 0.000 description 1
- USFZMSVCRYTOJT-UHFFFAOYSA-N Ammonium acetate Chemical compound N.CC(O)=O USFZMSVCRYTOJT-UHFFFAOYSA-N 0.000 description 1
- 239000005695 Ammonium acetate Substances 0.000 description 1
- 241000193403 Clostridium Species 0.000 description 1
- 241000186566 Clostridium ljungdahlii Species 0.000 description 1
- 241001611023 Clostridium ragsdalei Species 0.000 description 1
- 102100037458 Dephospho-CoA kinase Human genes 0.000 description 1
- 241000186541 Desulfotomaculum Species 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- OTMSDBZUPAUEDD-UHFFFAOYSA-N Ethane Chemical compound CC OTMSDBZUPAUEDD-UHFFFAOYSA-N 0.000 description 1
- 241000186394 Eubacterium Species 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 241000178985 Moorella Species 0.000 description 1
- 241000178986 Oxobacter Species 0.000 description 1
- 241000192031 Ruminococcus Species 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 240000000111 Saccharum officinarum Species 0.000 description 1
- 235000007201 Saccharum officinarum Nutrition 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- 238000002835 absorbance Methods 0.000 description 1
- 230000000789 acetogenic effect Effects 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- YBCVMFKXIKNREZ-UHFFFAOYSA-N acoh acetic acid Chemical compound CC(O)=O.CC(O)=O YBCVMFKXIKNREZ-UHFFFAOYSA-N 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 239000000809 air pollutant Substances 0.000 description 1
- 231100001243 air pollutant Toxicity 0.000 description 1
- 229940043376 ammonium acetate Drugs 0.000 description 1
- 235000019257 ammonium acetate Nutrition 0.000 description 1
- 125000000129 anionic group Chemical group 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000001651 autotrophic effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 239000003575 carbonaceous material Substances 0.000 description 1
- 239000003054 catalyst Substances 0.000 description 1
- 230000003197 catalytic effect Effects 0.000 description 1
- 238000004113 cell culture Methods 0.000 description 1
- 230000030833 cell death Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 230000002860 competitive effect Effects 0.000 description 1
- 230000001010 compromised effect Effects 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- 239000010779 crude oil Substances 0.000 description 1
- 108010049285 dephospho-CoA kinase Proteins 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 230000003292 diminished effect Effects 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000002803 fossil fuel Substances 0.000 description 1
- 239000012510 hollow fiber Substances 0.000 description 1
- 150000002431 hydrogen Chemical class 0.000 description 1
- 210000001822 immobilized cell Anatomy 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 150000007529 inorganic bases Chemical class 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- ZDGGJQMSELMHLK-UHFFFAOYSA-N m-Trifluoromethylhippuric acid Chemical compound OC(=O)CNC(=O)C1=CC=CC(C(F)(F)F)=C1 ZDGGJQMSELMHLK-UHFFFAOYSA-N 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000000696 methanogenic effect Effects 0.000 description 1
- 239000010813 municipal solid waste Substances 0.000 description 1
- 239000003345 natural gas Substances 0.000 description 1
- 239000011368 organic material Substances 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000008855 peristalsis Effects 0.000 description 1
- 230000000243 photosynthetic effect Effects 0.000 description 1
- 231100000572 poisoning Toxicity 0.000 description 1
- 230000000607 poisoning effect Effects 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 239000001294 propane Substances 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 239000012429 reaction media Substances 0.000 description 1
- 239000012465 retentate Substances 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 238000005464 sample preparation method Methods 0.000 description 1
- 238000007086 side reaction Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 230000001052 transient effect Effects 0.000 description 1
- 230000035899 viability Effects 0.000 description 1
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M21/00—Bioreactors or fermenters specially adapted for specific uses
- C12M21/12—Bioreactors or fermenters specially adapted for specific uses for producing fuels or solvents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/26—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/48—Automatic or computerized control
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/06—Ethanol, i.e. non-beverage
- C12P7/065—Ethanol, i.e. non-beverage with microorganisms other than yeasts
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B99/00—Subject matter not provided for in other groups of this subclass
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
Landscapes
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Biomedical Technology (AREA)
- Sustainable Development (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Computer Hardware Design (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Evolutionary Biology (AREA)
- Medical Informatics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Theoretical Computer Science (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14/329,881 | 2014-07-11 | ||
| US14/329,881 US9617566B2 (en) | 2014-07-11 | 2014-07-11 | Control of bioreactor processes |
| PCT/US2015/029563 WO2016007216A1 (en) | 2014-07-11 | 2015-05-06 | Control of bioreactor processes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112017000449A2 BR112017000449A2 (pt) | 2017-11-07 |
| BR112017000449B1 true BR112017000449B1 (pt) | 2022-10-25 |
Family
ID=55064652
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112017000449-6A BR112017000449B1 (pt) | 2014-07-11 | 2015-05-06 | Processo de fermentação |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US9617566B2 (enExample) |
| EP (2) | EP3766983A1 (enExample) |
| JP (2) | JP6599427B2 (enExample) |
| KR (1) | KR102531892B1 (enExample) |
| CN (1) | CN106574276B (enExample) |
| BR (1) | BR112017000449B1 (enExample) |
| CA (2) | CA3024631C (enExample) |
| EA (1) | EA033036B1 (enExample) |
| ES (1) | ES2841337T3 (enExample) |
| PL (1) | PL3167068T3 (enExample) |
| PT (1) | PT3167068T (enExample) |
| TW (2) | TWI673366B (enExample) |
| WO (1) | WO2016007216A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10017789B2 (en) | 2015-03-25 | 2018-07-10 | The Board Of Regents For Oklahoma State University | System and method for feedback control of gas supply for ethanol production via syngas fermentation using pH as a key control indicator |
| US10167445B2 (en) * | 2016-04-04 | 2019-01-01 | Hong Peng | Cell culture monitoring system with low power consumption |
| AU2018329846B2 (en) * | 2017-09-08 | 2024-01-11 | Lanzatech, Inc. | Processes and systems for metabolite production using hydrogen rich C1-containing substrates |
| JP7314151B2 (ja) * | 2018-02-09 | 2023-07-25 | グローバル・ライフ・サイエンシズ・ソリューションズ・ユーエスエー・エルエルシー | バイオプロセッシングのための使い捨てキット |
| US10889792B2 (en) | 2018-02-09 | 2021-01-12 | Global Life Sciences Solutions Usa Llc | Cell expansion vessel systems and methods |
| KR102276219B1 (ko) * | 2019-02-15 | 2021-07-12 | 씨제이제일제당 (주) | 생물반응기의 운전 조건을 결정하는 장치 및 방법 |
| KR102494796B1 (ko) * | 2020-04-20 | 2023-02-01 | 현대제철 주식회사 | 바이오 연료 제조방법 |
| WO2022217282A1 (en) | 2021-04-09 | 2022-10-13 | Lanzatech, Inc. | Process and apparatus for providing a feedstock |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5173429A (en) | 1990-11-09 | 1992-12-22 | The Board Of Trustees Of The University Of Arkansas | Clostridiumm ljungdahlii, an anaerobic ethanol and acetate producing microorganism |
| US5807722A (en) | 1992-10-30 | 1998-09-15 | Bioengineering Resources, Inc. | Biological production of acetic acid from waste gases with Clostridium ljungdahlii |
| US5593886A (en) | 1992-10-30 | 1997-01-14 | Gaddy; James L. | Clostridium stain which produces acetic acid from waste gases |
| UA72220C2 (uk) | 1998-09-08 | 2005-02-15 | Байоенджініерінг Рісорсиз, Інк. | Незмішувана з водою суміш розчинник/співрозчинник для екстрагування оцтової кислоти, спосіб одержання оцтової кислоти (варіанти), спосіб анаеробного мікробного бродіння для одержання оцтової кислоти (варіанти), модифікований розчинник та спосіб його одержання |
| WO2000019848A1 (en) | 1998-10-02 | 2000-04-13 | William Bruce Campbell Watkins | Measuring article and method for sizing compression garments |
| MXPA01011301A (es) | 1999-05-07 | 2003-07-14 | Bioengineering Resources Inc | Cepas clostridium que produce etanol a partir de gases que contienen substrato. |
| NZ523484A (en) * | 2000-07-25 | 2005-01-28 | Emmaus Foundation Inc | Methods for increasing the production of ethanol from microbial fermentation |
| US20090104594A1 (en) * | 2004-12-29 | 2009-04-23 | Biogen Idec | Bioreactor Process Control System and Method |
| NZ546496A (en) | 2006-04-07 | 2008-09-26 | Lanzatech New Zealand Ltd | Gas treatment process |
| NZ553984A (en) | 2007-03-19 | 2009-07-31 | Lanzatech New Zealand Ltd | Alcohol production process |
| WO2009022925A1 (en) | 2007-08-15 | 2009-02-19 | Lanzatech New Zealand Limited | Processes of producing alcohols |
| NZ560757A (en) | 2007-10-28 | 2010-07-30 | Lanzatech New Zealand Ltd | Improved carbon capture in microbial fermentation of industrial gases to ethanol |
| KR20130084704A (ko) * | 2008-03-12 | 2013-07-25 | 란자테크 뉴질랜드 리미티드 | 미생물 알콜 생산 방법 |
| JP5726760B2 (ja) | 2009-01-29 | 2015-06-03 | ランザテク・ニュージーランド・リミテッド | アルコールの製造方法 |
| PT2449121T (pt) * | 2009-07-02 | 2020-09-21 | Lanzatech New Zealand Ltd | Processo de produção de álcool |
| CA2784519A1 (en) | 2009-12-22 | 2011-06-30 | Ge Healthcare Bio-Sciences Ab | A method for controlling culture parameters in a bioreactor |
| TWI509073B (zh) | 2010-05-04 | 2015-11-21 | Lanzatech New Zealand Ltd | 改良之廢氣醱酵作用 |
| CA2786903C (en) * | 2010-07-28 | 2015-01-20 | Lanzatech New Zealand Limited | Novel bacteria and methods of use thereof for producing ethanol and acetate |
| US20130130339A1 (en) | 2010-07-31 | 2013-05-23 | Myriant Corporation | Fermentation process for the production of organic acids |
| MY159783A (en) | 2010-10-22 | 2017-01-31 | Lanzatech New Zealand Ltd | Methods and systems for the production of alcohols and/or acids |
| MY158746A (en) | 2010-10-22 | 2016-11-15 | Lanzatech New Zealand Ltd | Methods and systems for the production of hydrocarbon products |
| AU2011320544B2 (en) | 2010-10-29 | 2014-05-01 | Lanzatech Nz, Inc. | Methods and systems for the production of hydrocarbon products |
| US20130252277A1 (en) * | 2010-12-03 | 2013-09-26 | Ineos Bio Sa | Method of operation of fermentation of carbon monoxide containing gaseous substrate |
| US10100338B2 (en) * | 2012-05-22 | 2018-10-16 | Ineos Bio S.A. | Method of operation of a syngas fermentation process |
| US10233478B2 (en) | 2012-09-19 | 2019-03-19 | Ineos Bio Sa | Process for reducing CO2 emissions and increasing alcohol productivity in syngas fermentation |
| WO2014081848A1 (en) | 2012-11-20 | 2014-05-30 | Butamax Advanced Biofuels Llc | Butanol purification |
-
2014
- 2014-07-11 US US14/329,881 patent/US9617566B2/en active Active
-
2015
- 2015-05-06 CN CN201580042314.0A patent/CN106574276B/zh active Active
- 2015-05-06 CA CA3024631A patent/CA3024631C/en active Active
- 2015-05-06 PT PT158188805T patent/PT3167068T/pt unknown
- 2015-05-06 PL PL15818880T patent/PL3167068T3/pl unknown
- 2015-05-06 ES ES15818880T patent/ES2841337T3/es active Active
- 2015-05-06 EA EA201790136A patent/EA033036B1/ru not_active IP Right Cessation
- 2015-05-06 EP EP20195036.7A patent/EP3766983A1/en not_active Withdrawn
- 2015-05-06 CA CA2954496A patent/CA2954496C/en active Active
- 2015-05-06 BR BR112017000449-6A patent/BR112017000449B1/pt active IP Right Grant
- 2015-05-06 KR KR1020177002806A patent/KR102531892B1/ko active Active
- 2015-05-06 WO PCT/US2015/029563 patent/WO2016007216A1/en not_active Ceased
- 2015-05-06 JP JP2017501279A patent/JP6599427B2/ja active Active
- 2015-05-06 EP EP15818880.5A patent/EP3167068B1/en active Active
- 2015-06-02 TW TW107146822A patent/TWI673366B/zh active
- 2015-06-02 TW TW104117847A patent/TWI649426B/zh not_active IP Right Cessation
-
2017
- 2017-03-08 US US15/453,878 patent/US11753612B2/en active Active
-
2019
- 2019-05-29 JP JP2019100536A patent/JP6955531B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2019193636A (ja) | 2019-11-07 |
| CA2954496A1 (en) | 2016-01-14 |
| CA2954496C (en) | 2019-01-08 |
| US20170175064A1 (en) | 2017-06-22 |
| BR112017000449A2 (pt) | 2017-11-07 |
| EP3167068A1 (en) | 2017-05-17 |
| US9617566B2 (en) | 2017-04-11 |
| TW201625801A (zh) | 2016-07-16 |
| JP2017521077A (ja) | 2017-08-03 |
| TWI673366B (zh) | 2019-10-01 |
| PL3167068T3 (pl) | 2021-04-19 |
| CA3024631A1 (en) | 2016-01-14 |
| KR102531892B1 (ko) | 2023-05-11 |
| EA201790136A1 (ru) | 2017-05-31 |
| TW201920688A (zh) | 2019-06-01 |
| EP3167068B1 (en) | 2020-10-28 |
| KR20170028389A (ko) | 2017-03-13 |
| US20160010116A1 (en) | 2016-01-14 |
| US11753612B2 (en) | 2023-09-12 |
| EA033036B1 (ru) | 2019-08-30 |
| EP3766983A1 (en) | 2021-01-20 |
| WO2016007216A1 (en) | 2016-01-14 |
| JP6955531B2 (ja) | 2021-10-27 |
| ES2841337T3 (es) | 2021-07-08 |
| PT3167068T (pt) | 2020-12-21 |
| EP3167068A4 (en) | 2018-03-21 |
| CA3024631C (en) | 2022-03-15 |
| TWI649426B (zh) | 2019-02-01 |
| JP6599427B2 (ja) | 2019-10-30 |
| CN106574276A (zh) | 2017-04-19 |
| CN106574276B (zh) | 2020-11-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112017000449B1 (pt) | Processo de fermentação | |
| CN107076714B (zh) | 气体测试单元和方法 | |
| US10724059B2 (en) | Fermentation process | |
| CN107002012B (zh) | 多阶段生物反应器方法 | |
| BR112013013408B1 (pt) | processo para a produção de um ou mais alcoóis a partir de substrato gasoso compreendendo monóxido de carbono | |
| CN114929884A (zh) | 生物转化的过程控制 | |
| AU2017382765A1 (en) | Methods and systems using ionophores to control contamination in fermentation of gaseous substrates | |
| BR112015013011B1 (pt) | Método para fermentação microbiana de um substrato gasoso compreendendo co | |
| BRPI1008162B1 (pt) | Método para melhorar a eficiência da fermentação microbiana de um substrato compreendendo monóxido de carbono |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B25G | Requested change of headquarter approved |
Owner name: LANZATECH NEW ZEALAND LIMITED (NZ) |
|
| B25G | Requested change of headquarter approved |
Owner name: LANZATECH NEW ZEALAND LIMITED (NZ) |
|
| B25G | Requested change of headquarter approved |
Owner name: LANZATECH NEW ZEALAND LIMITED (NZ) |
|
| B25G | Requested change of headquarter approved |
Owner name: LANZATECH NEW ZEALAND LIMITED (US) |
|
| B25D | Requested change of name of applicant approved |
Owner name: LANZATECH NZ, INC. (US) |
|
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 06/05/2015, OBSERVADAS AS CONDICOES LEGAIS |