JP6599427B2 - バイオリアクタプロセスの制御 - Google Patents

バイオリアクタプロセスの制御 Download PDF

Info

Publication number
JP6599427B2
JP6599427B2 JP2017501279A JP2017501279A JP6599427B2 JP 6599427 B2 JP6599427 B2 JP 6599427B2 JP 2017501279 A JP2017501279 A JP 2017501279A JP 2017501279 A JP2017501279 A JP 2017501279A JP 6599427 B2 JP6599427 B2 JP 6599427B2
Authority
JP
Japan
Prior art keywords
concentration
measured
productivity
culture
flow rate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2017501279A
Other languages
English (en)
Japanese (ja)
Other versions
JP2017521077A (ja
JP2017521077A5 (enExample
Inventor
コレット,クリストフ
ウィリアム ウォーターズ,ガイ
カール ブロムリー,ジェーソン
イー ヤング,ジャスティン
ネイサン ウィルソン,ジャロッド
Original Assignee
ランザテク・ニュージーランド・リミテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ランザテク・ニュージーランド・リミテッド filed Critical ランザテク・ニュージーランド・リミテッド
Publication of JP2017521077A publication Critical patent/JP2017521077A/ja
Publication of JP2017521077A5 publication Critical patent/JP2017521077A5/ja
Priority to JP2019100536A priority Critical patent/JP6955531B2/ja
Application granted granted Critical
Publication of JP6599427B2 publication Critical patent/JP6599427B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00Bioreactors or fermenters specially adapted for specific uses
    • C12M21/12Bioreactors or fermenters specially adapted for specific uses for producing fuels or solvents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/26Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48Automatic or computerized control
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06Ethanol, i.e. non-beverage
    • C12P7/065Ethanol, i.e. non-beverage with microorganisms other than yeasts
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B99/00Subject matter not provided for in other groups of this subclass
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00Technologies for the production of fuel of non-fossil origin
    • Y02E50/10Biofuels, e.g. bio-diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Computer Hardware Design (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Evolutionary Biology (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2017501279A 2014-07-11 2015-05-06 バイオリアクタプロセスの制御 Active JP6599427B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2019100536A JP6955531B2 (ja) 2014-07-11 2019-05-29 バイオリアクタプロセスの制御

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14/329,881 2014-07-11
US14/329,881 US9617566B2 (en) 2014-07-11 2014-07-11 Control of bioreactor processes
PCT/US2015/029563 WO2016007216A1 (en) 2014-07-11 2015-05-06 Control of bioreactor processes

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019100536A Division JP6955531B2 (ja) 2014-07-11 2019-05-29 バイオリアクタプロセスの制御

Publications (3)

Publication Number Publication Date
JP2017521077A JP2017521077A (ja) 2017-08-03
JP2017521077A5 JP2017521077A5 (enExample) 2018-06-21
JP6599427B2 true JP6599427B2 (ja) 2019-10-30

Family

ID=55064652

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2017501279A Active JP6599427B2 (ja) 2014-07-11 2015-05-06 バイオリアクタプロセスの制御
JP2019100536A Active JP6955531B2 (ja) 2014-07-11 2019-05-29 バイオリアクタプロセスの制御

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2019100536A Active JP6955531B2 (ja) 2014-07-11 2019-05-29 バイオリアクタプロセスの制御

Country Status (13)

Country Link
US (2) US9617566B2 (enExample)
EP (2) EP3766983A1 (enExample)
JP (2) JP6599427B2 (enExample)
KR (1) KR102531892B1 (enExample)
CN (1) CN106574276B (enExample)
BR (1) BR112017000449B1 (enExample)
CA (2) CA3024631C (enExample)
EA (1) EA033036B1 (enExample)
ES (1) ES2841337T3 (enExample)
PL (1) PL3167068T3 (enExample)
PT (1) PT3167068T (enExample)
TW (2) TWI673366B (enExample)
WO (1) WO2016007216A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10017789B2 (en) 2015-03-25 2018-07-10 The Board Of Regents For Oklahoma State University System and method for feedback control of gas supply for ethanol production via syngas fermentation using pH as a key control indicator
US10167445B2 (en) * 2016-04-04 2019-01-01 Hong Peng Cell culture monitoring system with low power consumption
AU2018329846B2 (en) * 2017-09-08 2024-01-11 Lanzatech, Inc. Processes and systems for metabolite production using hydrogen rich C1-containing substrates
JP7314151B2 (ja) * 2018-02-09 2023-07-25 グローバル・ライフ・サイエンシズ・ソリューションズ・ユーエスエー・エルエルシー バイオプロセッシングのための使い捨てキット
US10889792B2 (en) 2018-02-09 2021-01-12 Global Life Sciences Solutions Usa Llc Cell expansion vessel systems and methods
KR102276219B1 (ko) * 2019-02-15 2021-07-12 씨제이제일제당 (주) 생물반응기의 운전 조건을 결정하는 장치 및 방법
KR102494796B1 (ko) * 2020-04-20 2023-02-01 현대제철 주식회사 바이오 연료 제조방법
WO2022217282A1 (en) 2021-04-09 2022-10-13 Lanzatech, Inc. Process and apparatus for providing a feedstock

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5173429A (en) 1990-11-09 1992-12-22 The Board Of Trustees Of The University Of Arkansas Clostridiumm ljungdahlii, an anaerobic ethanol and acetate producing microorganism
US5807722A (en) 1992-10-30 1998-09-15 Bioengineering Resources, Inc. Biological production of acetic acid from waste gases with Clostridium ljungdahlii
US5593886A (en) 1992-10-30 1997-01-14 Gaddy; James L. Clostridium stain which produces acetic acid from waste gases
UA72220C2 (uk) 1998-09-08 2005-02-15 Байоенджініерінг Рісорсиз, Інк. Незмішувана з водою суміш розчинник/співрозчинник для екстрагування оцтової кислоти, спосіб одержання оцтової кислоти (варіанти), спосіб анаеробного мікробного бродіння для одержання оцтової кислоти (варіанти), модифікований розчинник та спосіб його одержання
WO2000019848A1 (en) 1998-10-02 2000-04-13 William Bruce Campbell Watkins Measuring article and method for sizing compression garments
MXPA01011301A (es) 1999-05-07 2003-07-14 Bioengineering Resources Inc Cepas clostridium que produce etanol a partir de gases que contienen substrato.
NZ523484A (en) * 2000-07-25 2005-01-28 Emmaus Foundation Inc Methods for increasing the production of ethanol from microbial fermentation
US20090104594A1 (en) * 2004-12-29 2009-04-23 Biogen Idec Bioreactor Process Control System and Method
NZ546496A (en) 2006-04-07 2008-09-26 Lanzatech New Zealand Ltd Gas treatment process
NZ553984A (en) 2007-03-19 2009-07-31 Lanzatech New Zealand Ltd Alcohol production process
WO2009022925A1 (en) 2007-08-15 2009-02-19 Lanzatech New Zealand Limited Processes of producing alcohols
NZ560757A (en) 2007-10-28 2010-07-30 Lanzatech New Zealand Ltd Improved carbon capture in microbial fermentation of industrial gases to ethanol
KR20130084704A (ko) * 2008-03-12 2013-07-25 란자테크 뉴질랜드 리미티드 미생물 알콜 생산 방법
JP5726760B2 (ja) 2009-01-29 2015-06-03 ランザテク・ニュージーランド・リミテッド アルコールの製造方法
PT2449121T (pt) * 2009-07-02 2020-09-21 Lanzatech New Zealand Ltd Processo de produção de álcool
CA2784519A1 (en) 2009-12-22 2011-06-30 Ge Healthcare Bio-Sciences Ab A method for controlling culture parameters in a bioreactor
TWI509073B (zh) 2010-05-04 2015-11-21 Lanzatech New Zealand Ltd 改良之廢氣醱酵作用
CA2786903C (en) * 2010-07-28 2015-01-20 Lanzatech New Zealand Limited Novel bacteria and methods of use thereof for producing ethanol and acetate
US20130130339A1 (en) 2010-07-31 2013-05-23 Myriant Corporation Fermentation process for the production of organic acids
MY159783A (en) 2010-10-22 2017-01-31 Lanzatech New Zealand Ltd Methods and systems for the production of alcohols and/or acids
MY158746A (en) 2010-10-22 2016-11-15 Lanzatech New Zealand Ltd Methods and systems for the production of hydrocarbon products
AU2011320544B2 (en) 2010-10-29 2014-05-01 Lanzatech Nz, Inc. Methods and systems for the production of hydrocarbon products
US20130252277A1 (en) * 2010-12-03 2013-09-26 Ineos Bio Sa Method of operation of fermentation of carbon monoxide containing gaseous substrate
US10100338B2 (en) * 2012-05-22 2018-10-16 Ineos Bio S.A. Method of operation of a syngas fermentation process
US10233478B2 (en) 2012-09-19 2019-03-19 Ineos Bio Sa Process for reducing CO2 emissions and increasing alcohol productivity in syngas fermentation
WO2014081848A1 (en) 2012-11-20 2014-05-30 Butamax Advanced Biofuels Llc Butanol purification

Also Published As

Publication number Publication date
JP2019193636A (ja) 2019-11-07
CA2954496A1 (en) 2016-01-14
CA2954496C (en) 2019-01-08
US20170175064A1 (en) 2017-06-22
BR112017000449A2 (pt) 2017-11-07
EP3167068A1 (en) 2017-05-17
US9617566B2 (en) 2017-04-11
TW201625801A (zh) 2016-07-16
JP2017521077A (ja) 2017-08-03
BR112017000449B1 (pt) 2022-10-25
TWI673366B (zh) 2019-10-01
PL3167068T3 (pl) 2021-04-19
CA3024631A1 (en) 2016-01-14
KR102531892B1 (ko) 2023-05-11
EA201790136A1 (ru) 2017-05-31
TW201920688A (zh) 2019-06-01
EP3167068B1 (en) 2020-10-28
KR20170028389A (ko) 2017-03-13
US20160010116A1 (en) 2016-01-14
US11753612B2 (en) 2023-09-12
EA033036B1 (ru) 2019-08-30
EP3766983A1 (en) 2021-01-20
WO2016007216A1 (en) 2016-01-14
JP6955531B2 (ja) 2021-10-27
ES2841337T3 (es) 2021-07-08
PT3167068T (pt) 2020-12-21
EP3167068A4 (en) 2018-03-21
CA3024631C (en) 2022-03-15
TWI649426B (zh) 2019-02-01
CN106574276A (zh) 2017-04-19
CN106574276B (zh) 2020-11-06

Similar Documents

Publication Publication Date Title
JP6599427B2 (ja) バイオリアクタプロセスの制御
CN102471783A (zh) 醇生产方法
JP6662868B2 (ja) 複数ステージバイオリアクタープロセス
KR102807961B1 (ko) 일산화탄소 및 이산화탄소 생물 전환 방법
US12344882B2 (en) Automated bioconversion process for continuous and automatic control for co bioconversions

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20180507

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20180507

A871 Explanation of circumstances concerning accelerated examination

Free format text: JAPANESE INTERMEDIATE CODE: A871

Effective date: 20180507

A975 Report on accelerated examination

Free format text: JAPANESE INTERMEDIATE CODE: A971005

Effective date: 20180827

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20180829

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20180918

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20181218

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20190129

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20190529

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20190711

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20190903

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20191002

R150 Certificate of patent or registration of utility model

Ref document number: 6599427

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

S531 Written request for registration of change of domicile

Free format text: JAPANESE INTERMEDIATE CODE: R313531

S533 Written request for registration of change of name

Free format text: JAPANESE INTERMEDIATE CODE: R313533

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250