BR112016028637A2 - composições de carboidratos de baixa endotoxicina de alta pureza (hplc), e métodos de isolamento das mesmas - Google Patents

composições de carboidratos de baixa endotoxicina de alta pureza (hplc), e métodos de isolamento das mesmas

Info

Publication number
BR112016028637A2
BR112016028637A2 BR112016028637A BR112016028637A BR112016028637A2 BR 112016028637 A2 BR112016028637 A2 BR 112016028637A2 BR 112016028637 A BR112016028637 A BR 112016028637A BR 112016028637 A BR112016028637 A BR 112016028637A BR 112016028637 A2 BR112016028637 A2 BR 112016028637A2
Authority
BR
Brazil
Prior art keywords
isolating
endotoxicin
hplc
methods
high purity
Prior art date
Application number
BR112016028637A
Other languages
English (en)
Inventor
Thiyagarajan Bhaktavachalam
Cox Martina
Deorkar Nandu
Original Assignee
Avantor Performance Mat Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avantor Performance Mat Inc filed Critical Avantor Performance Mat Inc
Publication of BR112016028637A2 publication Critical patent/BR112016028637A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/02—Monosaccharides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/04—Disaccharides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
    • B01D15/361—Ion-exchange
    • B01D15/363—Anion-exchange

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Steroid Compounds (AREA)

Abstract

a presente invenção refere-se a uma composição de carboidratos altamente pura, e um método de preparação de uma composição de carboidratos altamente pura. o método inclui passar uma solução aquosa de carboidrato através de uma coluna de cromatografia de troca aniônica incluindo um meio cromatográfico de polietilenoimina (pei) para obter uma solução purificada e isolar uma composição de carboidrato altamente pura da solução purificada.
BR112016028637A 2014-06-13 2014-12-23 composições de carboidratos de baixa endotoxicina de alta pureza (hplc), e métodos de isolamento das mesmas BR112016028637A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462011810P 2014-06-13 2014-06-13
PCT/US2014/072117 WO2015191110A1 (en) 2014-06-13 2014-12-23 High purity low endotoxin carbohydrate (hple) compositions, and methods of isolation thereof

Publications (1)

Publication Number Publication Date
BR112016028637A2 true BR112016028637A2 (pt) 2017-08-22

Family

ID=54834052

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016028637A BR112016028637A2 (pt) 2014-06-13 2014-12-23 composições de carboidratos de baixa endotoxicina de alta pureza (hplc), e métodos de isolamento das mesmas

Country Status (8)

Country Link
US (1) US20170198002A1 (pt)
EP (1) EP3154994A4 (pt)
KR (1) KR102445863B1 (pt)
CN (1) CN106573948A (pt)
BR (1) BR112016028637A2 (pt)
SG (2) SG11201610316XA (pt)
TW (1) TWI670278B (pt)
WO (1) WO2015191110A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT3318281T (pt) * 2016-11-04 2023-02-07 Coriolis Pharma Res Gmbh Açúcares altamente purificados e composições de açúcar

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5589591A (en) * 1986-07-03 1996-12-31 Advanced Magnetics, Inc. Endotoxin-free polysaccharides
KR940000677B1 (ko) * 1991-05-10 1994-01-27 삼성전자 주식회사 광디스크 재생장치에 있어서 광픽업위치 제어회로
BR9400368A (pt) * 1993-02-02 1994-08-23 Ajinomoto Kk Processo para isolamento e purificação de trehalose
KR0129571B1 (ko) * 1994-04-23 1998-04-04 김영문 포도당 분획액(Raffinate)으로 의약용 결정포도당을 제조하는 방법
EP0693558B1 (en) * 1994-07-19 2002-12-04 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Trehalose and its production and use
JP2002210377A (ja) * 2001-01-22 2002-07-30 Tosoh Corp アニオン交換体、その製造方法及びそれを用いた用途
US20050033045A1 (en) * 2003-06-27 2005-02-10 Danisco Sweeteners Oy Separation method
FI20030963A0 (fi) * 2003-06-27 2003-06-27 Danisco Sweeteners Oy Erotusmenetelmä
MY144940A (en) * 2005-01-25 2011-11-30 Avantor Performance Mat Inc Chromatographic media
US8647857B2 (en) * 2008-04-30 2014-02-11 Gradalis, Inc. Processes for the digestion of colanic acid
KR101189640B1 (ko) * 2010-03-26 2012-10-12 씨제이제일제당 (주) Ｄ-사이코스 결정을 제조하는 방법

Also Published As

Publication number Publication date
KR20170018834A (ko) 2017-02-20
TWI670278B (zh) 2019-09-01
EP3154994A1 (en) 2017-04-19
US20170198002A1 (en) 2017-07-13
SG11201610316XA (en) 2017-01-27
KR102445863B1 (ko) 2022-09-20
CN106573948A (zh) 2017-04-19
EP3154994A4 (en) 2018-01-03
SG10201811099SA (en) 2019-01-30
TW201609782A (zh) 2016-03-16
WO2015191110A1 (en) 2015-12-17

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: AVANTOR PERFORMANCE MATERIALS, LLC. (US)

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 9A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2755 DE 24-10-2023 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.