BR112016028350A2 - ?método para encapsular material biológico, microesfera de hidrogel tridimensional e composição para transplante em um indivíduo? - Google Patents
?método para encapsular material biológico, microesfera de hidrogel tridimensional e composição para transplante em um indivíduo?Info
- Publication number
- BR112016028350A2 BR112016028350A2 BR112016028350A BR112016028350A BR112016028350A2 BR 112016028350 A2 BR112016028350 A2 BR 112016028350A2 BR 112016028350 A BR112016028350 A BR 112016028350A BR 112016028350 A BR112016028350 A BR 112016028350A BR 112016028350 A2 BR112016028350 A2 BR 112016028350A2
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- biological material
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5089—Processes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0241—Containing particulates characterized by their shape and/or structure
- A61K8/0283—Matrix particles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/042—Gels
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/736—Chitin; Chitosan; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/06—Making microcapsules or microballoons by phase separation
- B01J13/14—Polymerisation; cross-linking
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/20—After-treatment of capsule walls, e.g. hardening
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/04—Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0012—Cell encapsulation
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- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21K—TECHNIQUES FOR HANDLING PARTICLES OR IONISING RADIATION NOT OTHERWISE PROVIDED FOR; IRRADIATION DEVICES; GAMMA RAY OR X-RAY MICROSCOPES
- G21K5/00—Irradiation devices
- G21K5/02—Irradiation devices having no beam-forming means
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/10—General cosmetic use
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/41—Particular ingredients further characterized by their size
- A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/91—Injection
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/70—Polysaccharides
- C12N2533/74—Alginate
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Birds (AREA)
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- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
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- Dispersion Chemistry (AREA)
- Biotechnology (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Diabetes (AREA)
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- Dermatology (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Inorganic Chemistry (AREA)
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- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- High Energy & Nuclear Physics (AREA)
- Rheumatology (AREA)
- Emergency Medicine (AREA)
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Abstract
trata-se de um processo de gelificação de dentro para fora para gerar microcápsulas de hidrogel (também conhecidas como microesferas). os métodos para encapsular material biológico na matriz de hidrogel tridimensional de microesfera são descritos no presente documento. o processo compreende geralmente a formação de uma mistura de um composto precursor de hidrogel, um material biológico opcional e um cátion bivalente. a mistura é, então, combinada com alginato para gerar um invólucro de alginato ao redor das gotículas da mistura, seguido pela gelificação do núcleo de precursor de hidrogel e pela remoção do invólucro de alginato temporário para render microesferas autossustentáveis.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462007717P | 2014-06-04 | 2014-06-04 | |
US62/007,717 | 2014-06-04 | ||
PCT/US2015/034041 WO2015187862A1 (en) | 2014-06-04 | 2015-06-03 | Microencapsulation technique and products thereof |
Publications (2)
Publication Number | Publication Date |
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BR112016028350A2 true BR112016028350A2 (pt) | 2017-08-22 |
BR112016028350B1 BR112016028350B1 (pt) | 2021-02-02 |
Family
ID=54767332
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112016028350-3A BR112016028350B1 (pt) | 2014-06-04 | 2015-06-03 | método para encapsular material biológico |
Country Status (10)
Country | Link |
---|---|
US (1) | US9642814B2 (pt) |
EP (1) | EP3151809B1 (pt) |
JP (1) | JP6566970B2 (pt) |
CN (1) | CN106470666B (pt) |
AU (1) | AU2015269678B2 (pt) |
BR (1) | BR112016028350B1 (pt) |
CA (1) | CA2949716C (pt) |
DK (1) | DK3151809T3 (pt) |
ES (1) | ES2869461T3 (pt) |
WO (1) | WO2015187862A1 (pt) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102162453B1 (ko) * | 2018-02-22 | 2020-10-07 | 주식회사 휴모트메디컬 | 마스크 비드 및 그 제조 방법 |
US20210017348A1 (en) * | 2018-04-02 | 2021-01-21 | Optipharm Co., Ltd | Alginate microcapsules for cell encapsulation and, manufacturing method therefor |
KR102508357B1 (ko) * | 2018-10-23 | 2023-03-09 | (주)세포바이오 | 갈색지방 유래 간엽줄기세포의 골 분화를 이용한 개과 동물의 골 조직 재생용 세포치료제 및 이것의 제조 방법 |
CN110201612B (zh) * | 2019-05-20 | 2020-08-04 | 浙江大学 | 一种基于荧光微球监测肌细胞力学性质和收缩频率的核壳结构微球及其应用 |
EP3980075A4 (en) * | 2019-06-07 | 2023-07-12 | Likarda, LLC | MODULAR DEGRADATION IN HYDROGEL MICROPARTICLES |
EP4199879A1 (en) * | 2020-09-30 | 2023-06-28 | Ceref Asbl | Biodegradable microbeads comprising alginate from algae |
CN112315118A (zh) * | 2020-10-30 | 2021-02-05 | 陕西科技大学 | 添加艾草提取物的聚氨酯发泡鞋垫及其制备方法 |
CN117187153A (zh) * | 2022-05-30 | 2023-12-08 | 香港城市大学 | 基于水凝胶的细胞包裹方法、细胞或包裹有细胞的水凝胶颗粒及其体系、其用途及试剂盒 |
CN115721781B (zh) * | 2022-09-09 | 2023-11-07 | 哈尔滨工业大学(深圳) | 一种兼具细胞密度和机械强度的人工肌腱的制备工艺 |
Family Cites Families (16)
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GB1484562A (en) * | 1973-01-23 | 1977-09-14 | Unilever Ltd | Process for preparing encapsulated drops of fruit materia |
US4407957A (en) * | 1981-03-13 | 1983-10-04 | Damon Corporation | Reversible microencapsulation of a core material |
IL79052A0 (en) * | 1986-06-06 | 1986-11-30 | Univ Ramot | Device and process for production of alginate-shell beads containing biologically active material |
US5800829A (en) * | 1991-04-25 | 1998-09-01 | Brown University Research Foundation | Methods for coextruding immunoisolatory implantable vehicles with a biocompatible jacket and a biocompatible matrix core |
US5573934A (en) * | 1992-04-20 | 1996-11-12 | Board Of Regents, The University Of Texas System | Gels for encapsulation of biological materials |
US6793937B2 (en) * | 1999-10-22 | 2004-09-21 | 3M Innovative Properties Company | Method of delivering active material within hydrogel microbeads |
US20020034525A1 (en) * | 2000-06-30 | 2002-03-21 | Kao Corporation | Skin cosmetic composition |
US20040033265A1 (en) * | 2001-12-31 | 2004-02-19 | Industrial Technology Research Institute | Composite matrix containing chitosan derivatives and a process for making the same |
ATE390127T1 (de) * | 2003-09-01 | 2008-04-15 | Jpm The Jordanian Pharmaceutic | Universelle zusammensetzung zur kontrollierten wirkstoffabgabe enthaltend chitosan |
TWI293317B (en) * | 2003-12-31 | 2008-02-11 | Ind Tech Res Inst | Method for preparing polymer microspheres by aqueous phase-aqueous phase emulsion process |
CA2583308C (en) * | 2004-10-08 | 2020-01-07 | Georgia Tech Research Corporation | Microencapsulation of cells in hydrogels using electrostatic potentials |
CN100381568C (zh) * | 2005-04-27 | 2008-04-16 | 中国科学院沈阳应用生态研究所 | 一种生物微胶囊化的方法 |
US20070048295A1 (en) * | 2005-08-23 | 2007-03-01 | Ming-Ju Chen | Method for preparing alginate capsules |
EP2361640A1 (en) | 2010-02-25 | 2011-08-31 | Université de Liège | Cell cultivation in chitosan alginate hydrogel beads |
US20140127290A1 (en) * | 2012-11-08 | 2014-05-08 | Ohio State Innovation Foundation | Microcapsules Encapsulating Living Cells |
CN103820880B (zh) * | 2014-01-21 | 2016-04-20 | 东南大学 | 一种海藻酸钙纤维及其制备方法 |
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2015
- 2015-06-03 AU AU2015269678A patent/AU2015269678B2/en active Active
- 2015-06-03 CA CA2949716A patent/CA2949716C/en active Active
- 2015-06-03 ES ES15803221T patent/ES2869461T3/es active Active
- 2015-06-03 EP EP15803221.9A patent/EP3151809B1/en active Active
- 2015-06-03 CN CN201580029584.8A patent/CN106470666B/zh active Active
- 2015-06-03 US US14/730,071 patent/US9642814B2/en active Active
- 2015-06-03 JP JP2016571014A patent/JP6566970B2/ja active Active
- 2015-06-03 WO PCT/US2015/034041 patent/WO2015187862A1/en active Application Filing
- 2015-06-03 DK DK15803221.9T patent/DK3151809T3/da active
- 2015-06-03 BR BR112016028350-3A patent/BR112016028350B1/pt active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
ES2869461T3 (es) | 2021-10-25 |
AU2015269678B2 (en) | 2019-12-05 |
CN106470666B (zh) | 2021-01-01 |
EP3151809A1 (en) | 2017-04-12 |
DK3151809T3 (da) | 2021-05-25 |
AU2015269678A1 (en) | 2016-12-08 |
CN106470666A (zh) | 2017-03-01 |
BR112016028350B1 (pt) | 2021-02-02 |
WO2015187862A1 (en) | 2015-12-10 |
EP3151809B1 (en) | 2021-02-24 |
JP2017518310A (ja) | 2017-07-06 |
CA2949716C (en) | 2021-05-18 |
US20150352056A1 (en) | 2015-12-10 |
US9642814B2 (en) | 2017-05-09 |
CA2949716A1 (en) | 2015-12-10 |
JP6566970B2 (ja) | 2019-08-28 |
EP3151809A4 (en) | 2017-12-27 |
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