BR112016020366B1 - Anticorpo isolado que se liga a uma quimiocina de ligação a ccr3, molécula de ácido nucleico, vetor de expressão, célula hospedeira microbiana, e composição farmacêutica - Google Patents
Anticorpo isolado que se liga a uma quimiocina de ligação a ccr3, molécula de ácido nucleico, vetor de expressão, célula hospedeira microbiana, e composição farmacêutica Download PDFInfo
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Classifications
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/565—Complementarity determining region [CDR]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
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- Life Sciences & Earth Sciences (AREA)
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- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
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- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
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- Epidemiology (AREA)
Applications Claiming Priority (3)
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| US201461947852P | 2014-03-04 | 2014-03-04 | |
| US61/947,852 | 2014-03-04 | ||
| PCT/IL2015/050234 WO2015132790A2 (en) | 2014-03-04 | 2015-03-04 | Anti eotaxin-2 antibodies that recognize additional ccr3-binding chemokines |
Publications (2)
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| BR112016020366A2 BR112016020366A2 (pt) | 2018-06-05 |
| BR112016020366B1 true BR112016020366B1 (pt) | 2024-01-02 |
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| Application Number | Title | Priority Date | Filing Date |
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| BR112016020366-6A BR112016020366B1 (pt) | 2014-03-04 | 2015-03-04 | Anticorpo isolado que se liga a uma quimiocina de ligação a ccr3, molécula de ácido nucleico, vetor de expressão, célula hospedeira microbiana, e composição farmacêutica |
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| EP (2) | EP4155317A1 (enExample) |
| JP (1) | JP6553075B2 (enExample) |
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| WO2017183028A1 (en) * | 2016-04-18 | 2017-10-26 | Chemomab Ltd. | Eotaxin-2 inhibitors in the treatment of fibromyalgia |
| EP3551047A1 (en) | 2016-12-07 | 2019-10-16 | Progenity, Inc. | Gastrointestinal tract detection methods, devices and systems |
| CA3045310A1 (en) | 2016-12-14 | 2018-06-21 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with a chemokine/chemokine receptor inhibitor |
| WO2018139404A1 (ja) | 2017-01-24 | 2018-08-02 | 協和発酵キリン株式会社 | 放射線障害の治療又は予防剤並びに治療又は予防方法 |
| GB201702500D0 (en) | 2017-02-16 | 2017-04-05 | Univ Sheffield | Stable vamp reporter assay |
| IL251024A0 (en) * | 2017-03-08 | 2017-06-29 | Chemomab Ltd | Antibodies against eutaxin 2 for use in the treatment of liver diseases |
| CN116726362A (zh) | 2018-11-19 | 2023-09-12 | 比奥拉治疗股份有限公司 | 用生物治疗剂治疗疾病的方法和装置 |
| CN113613612B (zh) | 2019-03-08 | 2022-08-02 | 奥瑞斯健康公司 | 用于医疗系统和应用的倾斜机构 |
| CN115666704B (zh) | 2019-12-13 | 2025-09-26 | 比特比德科有限责任公司 | 用于将治疗剂递送至胃肠道的可摄取装置 |
| WO2021214758A1 (en) | 2020-04-20 | 2021-10-28 | Chemomab Ltd. | Ccl24 inhibitors in the treatment of covid-19 |
| EP4139352A1 (en) * | 2020-04-22 | 2023-03-01 | Chemomab Ltd. | Method of treatment using anti-ccl24 antibody |
| KR20230017207A (ko) * | 2020-04-30 | 2023-02-03 | 사이로파 비.브이. | 항-cd103 항체 |
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| IT1303736B1 (it) * | 1998-11-11 | 2001-02-23 | San Raffaele Centro Fond | Peptidi derivati da rantes con attivita' anti-hiv. |
| AU2007279079A1 (en) * | 2006-07-22 | 2008-01-31 | Oxagen Limited | Compounds having CRTH2 antagonist activity |
| CA2750952A1 (en) * | 2009-01-28 | 2010-08-05 | The Medical Research, Infrastructure, And Health Services Fund Of The Te L Aviv Medical Center | Eotaxin-2 (ccl24) inhibitors in inflammatory, autoimmune, and cardiovascular disorders |
| SI2470671T1 (sl) * | 2009-08-28 | 2015-04-30 | Regeneron Pharmaceuticals, Inc. | Antikinska protitelesa, ki se veĺ˝ejo na veäś kemokinov cc |
| GB201103837D0 (en) * | 2011-03-07 | 2011-04-20 | Oxagen Ltd | Amorphous (5-Fluoro-2-Methyl-3-Quinolin-2-Ylmethyl-Indol-1-Yl)-acetic acid |
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Also Published As
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| US20160368979A1 (en) | 2016-12-22 |
| IL247219A0 (en) | 2016-09-29 |
| WO2015132790A2 (en) | 2015-09-11 |
| CN106103479B (zh) | 2019-12-24 |
| RU2705255C2 (ru) | 2019-11-06 |
| EP3114139B1 (en) | 2022-06-15 |
| EP3114139A2 (en) | 2017-01-11 |
| US20190153088A1 (en) | 2019-05-23 |
| US10479830B2 (en) | 2019-11-19 |
| RU2016136639A3 (enExample) | 2018-05-04 |
| BR112016020366A2 (pt) | 2018-06-05 |
| PT3114139T (pt) | 2022-09-13 |
| EP4155317A1 (en) | 2023-03-29 |
| ES2926700T3 (es) | 2022-10-27 |
| US10246508B2 (en) | 2019-04-02 |
| JP2017508461A (ja) | 2017-03-30 |
| DK3114139T3 (da) | 2022-09-12 |
| CN106103479A (zh) | 2016-11-09 |
| JP6553075B2 (ja) | 2019-08-07 |
| IL247219B (en) | 2021-09-30 |
| RU2016136639A (ru) | 2018-04-05 |
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