BR112016019733A2 - - Google Patents

Info

Publication number
BR112016019733A2
BR112016019733A2 BR112016019733A BR112016019733A BR112016019733A2 BR 112016019733 A2 BR112016019733 A2 BR 112016019733A2 BR 112016019733 A BR112016019733 A BR 112016019733A BR 112016019733 A BR112016019733 A BR 112016019733A BR 112016019733 A2 BR112016019733 A2 BR 112016019733A2
Authority
BR
Brazil
Application number
BR112016019733A
Other languages
Portuguese (pt)
Other versions
BR112016019733B1 (pt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BR112016019733A2 publication Critical patent/BR112016019733A2/pt
Publication of BR112016019733B1 publication Critical patent/BR112016019733B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
BR112016019733-0A 2014-02-28 2015-02-27 Composto derivado de n2-fenil-pirido[3,4-d]pirimidina-2,8-diamina, composição farmacêutica, uso de um composto para a manufatura de um medicamento para tratar um distúrbio proliferativo, e, método para sintetizar um composto BR112016019733B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1403536.4A GB201403536D0 (en) 2014-02-28 2014-02-28 Inhibitor compounds
GB1403536.4 2014-02-28
PCT/GB2015/050590 WO2015128676A1 (en) 2014-02-28 2015-02-27 N2-phenyl-pyrido[3,4-d]pyrimidine-2,8-diamine derivatives and their use as mps1 inhibitors

Publications (2)

Publication Number Publication Date
BR112016019733A2 true BR112016019733A2 (enExample) 2017-08-15
BR112016019733B1 BR112016019733B1 (pt) 2022-12-20

Family

ID=50490546

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016019733-0A BR112016019733B1 (pt) 2014-02-28 2015-02-27 Composto derivado de n2-fenil-pirido[3,4-d]pirimidina-2,8-diamina, composição farmacêutica, uso de um composto para a manufatura de um medicamento para tratar um distúrbio proliferativo, e, método para sintetizar um composto

Country Status (11)

Country Link
US (2) US9902721B2 (enExample)
EP (2) EP3575299B1 (enExample)
JP (1) JP6440728B2 (enExample)
CN (1) CN106459035B (enExample)
AU (1) AU2015221956B2 (enExample)
BR (1) BR112016019733B1 (enExample)
CA (1) CA2939058C (enExample)
ES (2) ES2739148T3 (enExample)
GB (1) GB201403536D0 (enExample)
RU (1) RU2693460C2 (enExample)
WO (1) WO2015128676A1 (enExample)

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GB201403536D0 (en) * 2014-02-28 2014-04-16 Cancer Rec Tech Ltd Inhibitor compounds
GB201522532D0 (en) * 2015-12-21 2016-02-03 Cancer Rec Tech Ltd Novel pyrrolo[3,2-c]pyridine-6-amino derivatives
RS63004B1 (sr) * 2016-11-28 2022-03-31 Teijin Pharma Ltd Kristal pirido[3, 4-d]pirimidin derivata ili njegov solvat
ES2852123T3 (es) * 2016-11-28 2021-09-13 Teijin Pharma Ltd Derivados de ((piridin-2-il)-amino)pirido[3,4-d]pirimidina y ((piridazin-3-il)-amino)pirido[3,4-d]pirimidina como inhibidores de CDK4/6 para tratar p. ej. artritis reumatoide, arteriosclerosis, fibrosis pulmonar, infarto cerebral o cáncer
GB201709840D0 (en) * 2017-06-20 2017-08-02 Inst Of Cancer Research: Royal Cancer Hospital Methods and medical uses
JP2020524169A (ja) * 2017-06-20 2020-08-13 ジ・インスティチュート・オブ・キャンサー・リサーチ：ロイヤル・キャンサー・ホスピタル 方法および医学的利用
GB201809458D0 (en) 2018-06-08 2018-07-25 Crt Pioneer Fund Lp Salt form
GB201809460D0 (en) 2018-06-08 2018-07-25 Crt Pioneer Fund Lp Salt form
CA3130478A1 (en) * 2019-03-13 2020-09-17 Voronoi Co., Ltd. Heteroaryl derivatives, and pharmaceutical composition comprising the same as active ingredient
CN115385840B (zh) * 2022-09-05 2024-07-02 北京京宇复瑞科技集团有限责任公司 制备3-甲氧基氮杂环丁烷盐酸盐的方法

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Also Published As

Publication number Publication date
AU2015221956A1 (en) 2016-07-07
EP3110816A1 (en) 2017-01-04
JP2017506661A (ja) 2017-03-09
US9902721B2 (en) 2018-02-27
WO2015128676A1 (en) 2015-09-03
ES2739148T3 (es) 2020-01-29
RU2693460C2 (ru) 2019-07-03
AU2015221956B2 (en) 2019-05-09
EP3110816B1 (en) 2019-06-19
GB201403536D0 (en) 2014-04-16
JP6440728B2 (ja) 2018-12-19
RU2016137789A (ru) 2018-04-03
RU2016137789A3 (enExample) 2018-10-23
EP3575299A1 (en) 2019-12-04
CN106459035A (zh) 2017-02-22
US20160362409A1 (en) 2016-12-15
CA2939058A1 (en) 2015-09-03
EP3575299B1 (en) 2022-07-20
CA2939058C (en) 2022-04-26
ES2926641T3 (es) 2022-10-27
BR112016019733B1 (pt) 2022-12-20
US20180194761A1 (en) 2018-07-12
US10399974B2 (en) 2019-09-03
CN106459035B (zh) 2018-04-06

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07B Technical examination (opinion): publication cancelled [chapter 7.2 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 27/02/2015, OBSERVADAS AS CONDICOES LEGAIS

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 10A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2822 DE 04-02-2025 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.