BR112016009606A2 - Uso antiangiogênico de fitocomplexos líquidos a partir de azeitona - Google Patents
Uso antiangiogênico de fitocomplexos líquidos a partir de azeitonaInfo
- Publication number
- BR112016009606A2 BR112016009606A2 BR112016009606A BR112016009606A BR112016009606A2 BR 112016009606 A2 BR112016009606 A2 BR 112016009606A2 BR 112016009606 A BR112016009606 A BR 112016009606A BR 112016009606 A BR112016009606 A BR 112016009606A BR 112016009606 A2 BR112016009606 A2 BR 112016009606A2
- Authority
- BR
- Brazil
- Prior art keywords
- inflammation
- angiogenesis
- olive
- phytocomplex
- liquid
- Prior art date
Links
- 240000007817 Olea europaea Species 0.000 title abstract 4
- 230000001772 anti-angiogenic effect Effects 0.000 title abstract 2
- 239000007788 liquid Substances 0.000 title abstract 2
- 206010061218 Inflammation Diseases 0.000 abstract 5
- 230000004054 inflammatory process Effects 0.000 abstract 5
- 230000033115 angiogenesis Effects 0.000 abstract 4
- JUUBCHWRXWPFFH-UHFFFAOYSA-N Hydroxytyrosol Chemical compound OCCC1=CC=C(O)C(O)=C1 JUUBCHWRXWPFFH-UHFFFAOYSA-N 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 239000012141 concentrate Substances 0.000 abstract 2
- 150000008442 polyphenolic compounds Chemical class 0.000 abstract 2
- 230000002265 prevention Effects 0.000 abstract 2
- 241000207836 Olea <angiosperm> Species 0.000 abstract 1
- 208000034038 Pathologic Neovascularization Diseases 0.000 abstract 1
- 229940095066 hydroxytyrosol Drugs 0.000 abstract 1
- 235000003248 hydroxytyrosol Nutrition 0.000 abstract 1
- -1 hydroxytyrosol and 3 Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000007170 pathology Effects 0.000 abstract 1
- 235000013824 polyphenols Nutrition 0.000 abstract 1
- 239000003643 water by type Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/05—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Mycology (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Non-Alcoholic Beverages (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
USO ANTIANGIOGÊNICO DE FITOCOMPLEXOS LÍQUIDOS A PARTIR DE AZEITONA. A presente invenção se refere a um fitocomplexo ou concentrado natural rico em compostos polifenólicos, tais como hidroxitirosol e 3,4-DHPA-EDA, derivados das águas de vegetação de azeitonas oleaginosas ou de bagaço de azeitona resultante do processo de prensagem de azeitona para uso no tratamento e na prevenção de angiogênese e inflamação. Em particular, a angiogênese e inflamação às quais é feita referência é angiogênese patológica e inflamação, por exemplo, que sustenta o desenvolvimento e propagação de um tumor ou angiogênese e inflamação ligadas a patologias não tumorais. A presente invenção ainda se refere a uma bebida que compreende o concentrado de polifenol e o uso do mesmo no tratamento e na prevenção de angiogênese e de inflamação.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT001814A ITMI20131814A1 (it) | 2013-10-31 | 2013-10-31 | Uso antiangiogenico di fitocomplessi liquidi da olive |
PCT/IB2014/065746 WO2015063736A1 (en) | 2013-10-31 | 2014-10-31 | Antiangiogenic use of liquid phytocomplexes from olive |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112016009606A2 true BR112016009606A2 (pt) | 2017-09-19 |
Family
ID=49780190
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112016009606A BR112016009606A2 (pt) | 2013-10-31 | 2014-10-31 | Uso antiangiogênico de fitocomplexos líquidos a partir de azeitona |
Country Status (9)
Country | Link |
---|---|
US (1) | US10226498B2 (pt) |
EP (1) | EP3062805B1 (pt) |
JP (1) | JP6687527B2 (pt) |
CN (1) | CN105744943B (pt) |
BR (1) | BR112016009606A2 (pt) |
CA (1) | CA2928913A1 (pt) |
HK (1) | HK1221903A1 (pt) |
IT (1) | ITMI20131814A1 (pt) |
WO (1) | WO2015063736A1 (pt) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ITMI20131815A1 (it) * | 2013-10-31 | 2015-05-01 | Fattoria La Vialla Di Gianni Anton Io E Bandino L | Uso antinfiammatorio di fitocomplessi liquidi da olive |
IT201700042090A1 (it) * | 2017-04-14 | 2018-10-14 | Levius Vita Foods Srl | Procedimento per la preparazione di olio d’oliva ad alto contenuto di idrossitirosolo |
US11918007B2 (en) | 2017-12-14 | 2024-03-05 | Universidade Do Porto | Foodstuff composition comprising a derivate of olive pomace |
IT201800002266A1 (it) * | 2018-01-31 | 2019-07-31 | Fattoria La Vialla Di Gianni Antonio E Bandino Lo Franco Soc Agricola Semplice | Uso cosmetico di acque di vegetazione |
IT201800004123A1 (it) * | 2018-03-30 | 2019-09-30 | Fattoria La Vialla Di Gianni Antonio E Bandino Lo Franco Soc Agricola Semplice | Acque di vegetazione ed usi derivati |
IT201800005151A1 (it) * | 2018-05-08 | 2019-11-08 | Estratto di acque di vegetazione per uso nel trattamento e/o nella prevenzione del cancro prostatico | |
US11980211B2 (en) | 2018-07-12 | 2024-05-14 | International Flavors & Fragrances | Verbascoside and related compounds for sweetness enhancement |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3730868A1 (de) * | 1987-09-15 | 1989-03-23 | Henkel Kgaa | Verfahren zur abtrennung von biotechnisch hergestellten wertstoffen aus einer fermenterbruehe durch querstrom-mikro- und/oder ultrafiltration |
ITRM20040292A1 (it) * | 2004-06-16 | 2004-09-16 | Enea Ente Nuove Tec | Procedimento di recupero integrale di componenti chimiche delle acque di vegetazione con tecnologie di membrana. |
ITMI20041627A1 (it) * | 2004-08-06 | 2004-11-06 | Lachifarma S R L Lab Chimi Co | Processo per il recupero di tirosolo idrossitirosolo e altri componenti fenolici da acque di vegetazione e metodo di ossidazione catalitica di tirosolo a idrossitirosolo |
US8841264B2 (en) | 2006-07-14 | 2014-09-23 | Dsm Ip Assets B.V. | Compositions |
NO325550B1 (no) * | 2006-10-31 | 2008-06-16 | Due Miljo As | Fremgangsmate for rensing av oljer og anvendelse av slike i mat og fôr |
AU2008278764A1 (en) * | 2007-07-23 | 2009-01-29 | Probelte Pharma, S.A. | Fortification of nutritional products with olive extracts containing hydroxytyrosol and hydroxytyrosol fortified nutritional products |
GB0807673D0 (en) | 2008-04-28 | 2008-06-04 | Bio Actor Bcba | Polyphenolic extract |
ITMI20110941A1 (it) * | 2011-05-25 | 2012-11-26 | Phenofarm S R L | Processo di produzione di un fito-estratto da acque di vegetazione esanse olearie |
JP2013034971A (ja) * | 2011-08-10 | 2013-02-21 | M2 Planning:Kk | 飲料水供給装置 |
ITMI20131815A1 (it) * | 2013-10-31 | 2015-05-01 | Fattoria La Vialla Di Gianni Anton Io E Bandino L | Uso antinfiammatorio di fitocomplessi liquidi da olive |
-
2013
- 2013-10-31 IT IT001814A patent/ITMI20131814A1/it unknown
-
2014
- 2014-10-31 CA CA2928913A patent/CA2928913A1/en active Pending
- 2014-10-31 WO PCT/IB2014/065746 patent/WO2015063736A1/en active Application Filing
- 2014-10-31 EP EP14806442.1A patent/EP3062805B1/en active Active
- 2014-10-31 CN CN201480060255.5A patent/CN105744943B/zh active Active
- 2014-10-31 BR BR112016009606A patent/BR112016009606A2/pt not_active Application Discontinuation
- 2014-10-31 US US15/033,586 patent/US10226498B2/en active Active
- 2014-10-31 JP JP2016551094A patent/JP6687527B2/ja active Active
-
2016
- 2016-08-23 HK HK16110023.2A patent/HK1221903A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
HK1221903A1 (zh) | 2017-06-16 |
EP3062805B1 (en) | 2019-08-28 |
WO2015063736A1 (en) | 2015-05-07 |
US20160250272A1 (en) | 2016-09-01 |
CN105744943B (zh) | 2020-10-09 |
EP3062805A1 (en) | 2016-09-07 |
JP2017501209A (ja) | 2017-01-12 |
US10226498B2 (en) | 2019-03-12 |
CN105744943A (zh) | 2016-07-06 |
CA2928913A1 (en) | 2015-05-07 |
ITMI20131814A1 (it) | 2015-05-01 |
JP6687527B2 (ja) | 2020-04-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR112016009605A2 (pt) | Uso antiinflamatório de fitocomplexos líquidos a partir de azeitona | |
BR112016009606A2 (pt) | Uso antiangiogênico de fitocomplexos líquidos a partir de azeitona | |
CL2019001143A1 (es) | Dímeros de insulina, agonistas parciales del receptor de insulina (divisional solicitud 201701288) | |
BR112014004859A2 (pt) | preparação e composições de enxofre zerovalente altamente biodisponíveis e usos das mesmas | |
BR112018000632A8 (pt) | Moléculas de anticorpo que ligam a cd79 | |
BR112015022417A2 (pt) | métodos e composições para inibição de proteínas contendo bromodomínio | |
ECSP14017269A (es) | Compuestos para tratar la atrofia muscular espinal | |
ECSP13012573A (es) | 6-amino-nicotinamidas sustituidas como moduladores de KCNQ2/3 | |
DOP2013000300A (es) | Pirrolotriazinas sustituidas con hidroximetilarilo y sus usos | |
UY35276A (es) | Nuevos compuestos que inhiben la actividad de Lp-PLA2 | |
CO7101239A2 (es) | Composiciones derivadas de la quitosana | |
BR112018003745A2 (pt) | composições que compreendem um composto de urolitina | |
EP2676703A3 (en) | Methods of lightening the skin | |
GT201400242A (es) | "nuevos compuestos de pirazol" | |
EA201500270A1 (ru) | Фторметилзамещенные пирролкарбоксамиды | |
AR085049A1 (es) | Uso de al menos un coproducto de la industria del refinamiento de aceites vegetales para obtener un insaponificable total purificado de aceite vegetal | |
BR112014017587A2 (pt) | métodos e formulações para o tratamento de deficiências de ácido siálico | |
ECSP13012460A (es) | 2-oxo- y 2-tioxo-dihidroquinolina-3-carboxamidas sustituidos como moduladores KCNQ2/3 | |
MX2013015419A (es) | Dha y epa en la reduccion de estres oxidante. | |
MX2016007955A (es) | Pirrol carboxamidas iii fluorometil-sustituidas. | |
MX364528B (es) | Witanólidos útiles para el tratamiento de enfermedades neurodegenerativas. | |
MX2014006559A (es) | Composicion para el tratamiento o reduccion de sintomas relacionados para el sindrome premestrual (pms), desorden disforico premenstrual (pmdd), premenopausia, menopausia, o desordenes hormonales femeninos en una composicion farmaceutica que contiene dicha forma, y proceso para producir la forma farmaceutica y uso de la composicion. | |
BR112017002475A2 (pt) | composições e método cosmético não terapêutico | |
MX2017003100A (es) | Composiciones terapeuticas y nutricionales para trastornos gastrointestinales funcionales. | |
EP3071543A4 (en) | Acetyl salicyclic acid dimers, synthesis thereof, and uses thereof to prevent and treat complement-mediated disorders |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL |