BR112015022257A8 - tratamento de deficiência do hormônio do crescimento pediátrica com análogos de hormônio do crescimento humano - Google Patents

tratamento de deficiência do hormônio do crescimento pediátrica com análogos de hormônio do crescimento humano

Info

Publication number
BR112015022257A8
BR112015022257A8 BR112015022257A BR112015022257A BR112015022257A8 BR 112015022257 A8 BR112015022257 A8 BR 112015022257A8 BR 112015022257 A BR112015022257 A BR 112015022257A BR 112015022257 A BR112015022257 A BR 112015022257A BR 112015022257 A8 BR112015022257 A8 BR 112015022257A8
Authority
BR
Brazil
Prior art keywords
growth hormone
pediatric
treatment
xten
human growth
Prior art date
Application number
BR112015022257A
Other languages
English (en)
Portuguese (pt)
Other versions
BR112015022257A2 (pt
Inventor
Humphriss Eric
M Bright George
L Cleland Jeffrey
Original Assignee
Amunix Operating Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amunix Operating Inc filed Critical Amunix Operating Inc
Publication of BR112015022257A2 publication Critical patent/BR112015022257A2/pt
Publication of BR112015022257A8 publication Critical patent/BR112015022257A8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
BR112015022257A 2013-03-11 2014-03-10 tratamento de deficiência do hormônio do crescimento pediátrica com análogos de hormônio do crescimento humano BR112015022257A8 (pt)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US201361776618P 2013-03-11 2013-03-11
US201361810786P 2013-04-11 2013-04-11
US201361835002P 2013-06-14 2013-06-14
US201361880701P 2013-09-20 2013-09-20
US201361911731P 2013-12-04 2013-12-04
US201461931987P 2014-01-27 2014-01-27
US201461948457P 2014-03-05 2014-03-05
PCT/US2014/022850 WO2014164568A1 (en) 2013-03-11 2014-03-10 Treatment of pediatric growth hormone deficiency with human growth hormone analogues

Publications (2)

Publication Number Publication Date
BR112015022257A2 BR112015022257A2 (pt) 2017-10-10
BR112015022257A8 true BR112015022257A8 (pt) 2018-01-23

Family

ID=51658905

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015022257A BR112015022257A8 (pt) 2013-03-11 2014-03-10 tratamento de deficiência do hormônio do crescimento pediátrica com análogos de hormônio do crescimento humano

Country Status (16)

Country Link
US (1) US20160158321A1 (https=)
EP (1) EP2968451A4 (https=)
JP (3) JP2016514132A (https=)
KR (1) KR20150124955A (https=)
CN (1) CN105209055A (https=)
AU (1) AU2014249258A1 (https=)
BR (1) BR112015022257A8 (https=)
CA (1) CA2900949A1 (https=)
CL (1) CL2015002456A1 (https=)
EA (1) EA201591529A1 (https=)
HK (1) HK1216617A1 (https=)
IL (1) IL240392A0 (https=)
MX (1) MX2015012175A (https=)
PH (1) PH12015502063A1 (https=)
SG (1) SG11201506732YA (https=)
WO (1) WO2014164568A1 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9849188B2 (en) 2009-06-08 2017-12-26 Amunix Operating Inc. Growth hormone polypeptides and methods of making and using same
WO2016109823A1 (en) * 2015-01-02 2016-07-07 Amunix Operation Inc. Treatment of pediatric growth hormone deficiency with human growth hormone analogues
US20180028111A1 (en) 2015-02-03 2018-02-01 Apple Inc. Family sleep monitoring system
IL319047A (en) 2015-08-28 2025-04-01 Amunix Operating Inc Chimeric polypeptide composition and methods for its preparation and use
WO2017136583A1 (en) 2016-02-02 2017-08-10 Versartis, Inc. Growth hormone treatment adherence system
CN109152816B (zh) * 2016-02-17 2022-08-16 株式会社吉耐森 用于治疗生长激素缺乏症的包含重组hgh的药物组合物
RU2748402C2 (ru) * 2016-08-30 2021-05-25 Дженексин,Инк. ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ ДЛЯ ТЕРАПИИ ДЕФИЦИТА ГОРМОНА РОСТА, СОДЕРЖАЩАЯ СЛИТЫЙ БЕЛОК hGH
US10288629B1 (en) * 2017-12-19 2019-05-14 Aeterna Zentaris, Inc. Method of assessing growth hormone deficiency in humans by a macimorelin containing composition
AU2018393111B2 (en) 2017-12-21 2025-07-10 Amunix Pharmaceuticals, Inc. Release segments and binding compositions comprising same
US11903683B2 (en) 2018-08-03 2024-02-20 Chelak Medical Solutions Inc Non-barometric determination of hemodynamic effects of cardiac arrhythmias using signals sensed by an implantable device
RU2753191C2 (ru) * 2019-09-26 2021-08-12 Федеральное государственное бюджетное учреждение науки Институт Биологии Развития им. Н.К. Кольцова Российской Академии Наук Новый рекомбинантный аналог гормона роста пролонгированного действия
EP4085077A4 (en) 2019-12-31 2024-01-17 Beijing QL Biopharmaceutical Co., Ltd. Fusion proteins of glp-1 and gdf15 and conjugates thereof
CN113728013B (zh) 2020-01-11 2022-06-14 北京质肽生物医药科技有限公司 Glp-1和fgf21的融合蛋白的缀合物
KR102599111B1 (ko) * 2020-01-31 2023-11-07 울산대학교 산학협력단 인슐린유사성장인자-1 융합단백질 및 이의 용도
MX2023000935A (es) * 2020-07-22 2023-02-22 Aeterna Zentaris Gmbh Un metodo de deteccion para diagnosticar la deficiencia de la hormona del crecimiento en pacientes pediatricos utilizando macimorelina.
CN114729060B (zh) 2020-09-30 2022-11-25 北京质肽生物医药科技有限公司 多肽缀合物和使用方法
EP4323413A4 (en) 2022-03-30 2025-10-15 Beijing Ql Biopharmaceutical Co Ltd LIQUID PHARMACEUTICAL COMPOSITIONS OF POLYPEPTIDE CONJUGATES AND METHODS OF USE THEREOF

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2610356T3 (es) * 2009-02-03 2017-04-27 Amunix Operating Inc. Polipéptidos recombinantes extendidos y composiciones que comprenden los mismos
EP2473850B1 (en) * 2009-09-02 2015-05-13 Merck Serono S.A. Method of predicting the level of growth response
CN104519903A (zh) * 2012-06-05 2015-04-15 阿穆尼克斯运营公司 Hgh-xten融合蛋白及其在治疗生长激素缺乏中的用途

Also Published As

Publication number Publication date
HK1216617A1 (zh) 2016-11-25
WO2014164568A1 (en) 2014-10-09
SG11201506732YA (en) 2015-09-29
EP2968451A4 (en) 2017-01-04
EP2968451A1 (en) 2016-01-20
AU2014249258A1 (en) 2015-08-27
KR20150124955A (ko) 2015-11-06
US20160158321A1 (en) 2016-06-09
CN105209055A (zh) 2015-12-30
MX2015012175A (es) 2016-01-12
CA2900949A1 (en) 2014-10-09
JP2017101074A (ja) 2017-06-08
BR112015022257A2 (pt) 2017-10-10
IL240392A0 (en) 2015-09-24
JP2016514132A (ja) 2016-05-19
EA201591529A1 (ru) 2016-04-29
JP2019056013A (ja) 2019-04-11
CL2015002456A1 (es) 2016-05-27
PH12015502063A1 (en) 2016-01-25

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2506 DE 15-01-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI