HK1216617A1 - 用人生长激素类似物治疗小儿生长激素缺乏症 - Google Patents

用人生长激素类似物治疗小儿生长激素缺乏症 Download PDF

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Publication number
HK1216617A1
HK1216617A1 HK16104695.2A HK16104695A HK1216617A1 HK 1216617 A1 HK1216617 A1 HK 1216617A1 HK 16104695 A HK16104695 A HK 16104695A HK 1216617 A1 HK1216617 A1 HK 1216617A1
Authority
HK
Hong Kong
Prior art keywords
growth hormone
pediatric
xten
treatment
therapy
Prior art date
Application number
HK16104695.2A
Other languages
English (en)
Chinese (zh)
Inventor
L. Cleland Jeffrey
M. Bright George
Humphriss Eric
Original Assignee
Amunix Operating Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amunix Operating Inc. filed Critical Amunix Operating Inc.
Publication of HK1216617A1 publication Critical patent/HK1216617A1/zh

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
HK16104695.2A 2013-03-11 2014-03-10 用人生长激素类似物治疗小儿生长激素缺乏症 HK1216617A1 (zh)

Applications Claiming Priority (15)

Application Number Priority Date Filing Date Title
US201361776618P 2013-03-11 2013-03-11
US61/776,618 2013-03-11
US201361810786P 2013-04-11 2013-04-11
US61/810,786 2013-04-11
US201361835002P 2013-06-14 2013-06-14
US61/835,002 2013-06-14
US201361880701P 2013-09-20 2013-09-20
US61/880,701 2013-09-20
US201361911731P 2013-12-04 2013-12-04
US61/911,731 2013-12-04
US201461931987P 2014-01-27 2014-01-27
US61/931,987 2014-01-27
US201461948457P 2014-03-05 2014-03-05
US61/948,457 2014-03-05
PCT/US2014/022850 WO2014164568A1 (en) 2013-03-11 2014-03-10 Treatment of pediatric growth hormone deficiency with human growth hormone analogues

Publications (1)

Publication Number Publication Date
HK1216617A1 true HK1216617A1 (zh) 2016-11-25

Family

ID=51658905

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16104695.2A HK1216617A1 (zh) 2013-03-11 2014-03-10 用人生长激素类似物治疗小儿生长激素缺乏症

Country Status (16)

Country Link
US (1) US20160158321A1 (https=)
EP (1) EP2968451A4 (https=)
JP (3) JP2016514132A (https=)
KR (1) KR20150124955A (https=)
CN (1) CN105209055A (https=)
AU (1) AU2014249258A1 (https=)
BR (1) BR112015022257A8 (https=)
CA (1) CA2900949A1 (https=)
CL (1) CL2015002456A1 (https=)
EA (1) EA201591529A1 (https=)
HK (1) HK1216617A1 (https=)
IL (1) IL240392A0 (https=)
MX (1) MX2015012175A (https=)
PH (1) PH12015502063A1 (https=)
SG (1) SG11201506732YA (https=)
WO (1) WO2014164568A1 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9849188B2 (en) 2009-06-08 2017-12-26 Amunix Operating Inc. Growth hormone polypeptides and methods of making and using same
WO2016109823A1 (en) * 2015-01-02 2016-07-07 Amunix Operation Inc. Treatment of pediatric growth hormone deficiency with human growth hormone analogues
US20180028111A1 (en) 2015-02-03 2018-02-01 Apple Inc. Family sleep monitoring system
IL319047A (en) 2015-08-28 2025-04-01 Amunix Operating Inc Chimeric polypeptide composition and methods for its preparation and use
WO2017136583A1 (en) 2016-02-02 2017-08-10 Versartis, Inc. Growth hormone treatment adherence system
CN109152816B (zh) * 2016-02-17 2022-08-16 株式会社吉耐森 用于治疗生长激素缺乏症的包含重组hgh的药物组合物
RU2748402C2 (ru) * 2016-08-30 2021-05-25 Дженексин,Инк. ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ ДЛЯ ТЕРАПИИ ДЕФИЦИТА ГОРМОНА РОСТА, СОДЕРЖАЩАЯ СЛИТЫЙ БЕЛОК hGH
US10288629B1 (en) * 2017-12-19 2019-05-14 Aeterna Zentaris, Inc. Method of assessing growth hormone deficiency in humans by a macimorelin containing composition
AU2018393111B2 (en) 2017-12-21 2025-07-10 Amunix Pharmaceuticals, Inc. Release segments and binding compositions comprising same
US11903683B2 (en) 2018-08-03 2024-02-20 Chelak Medical Solutions Inc Non-barometric determination of hemodynamic effects of cardiac arrhythmias using signals sensed by an implantable device
RU2753191C2 (ru) * 2019-09-26 2021-08-12 Федеральное государственное бюджетное учреждение науки Институт Биологии Развития им. Н.К. Кольцова Российской Академии Наук Новый рекомбинантный аналог гормона роста пролонгированного действия
EP4085077A4 (en) 2019-12-31 2024-01-17 Beijing QL Biopharmaceutical Co., Ltd. Fusion proteins of glp-1 and gdf15 and conjugates thereof
CN113728013B (zh) 2020-01-11 2022-06-14 北京质肽生物医药科技有限公司 Glp-1和fgf21的融合蛋白的缀合物
KR102599111B1 (ko) * 2020-01-31 2023-11-07 울산대학교 산학협력단 인슐린유사성장인자-1 융합단백질 및 이의 용도
MX2023000935A (es) * 2020-07-22 2023-02-22 Aeterna Zentaris Gmbh Un metodo de deteccion para diagnosticar la deficiencia de la hormona del crecimiento en pacientes pediatricos utilizando macimorelina.
CN114729060B (zh) 2020-09-30 2022-11-25 北京质肽生物医药科技有限公司 多肽缀合物和使用方法
EP4323413A4 (en) 2022-03-30 2025-10-15 Beijing Ql Biopharmaceutical Co Ltd LIQUID PHARMACEUTICAL COMPOSITIONS OF POLYPEPTIDE CONJUGATES AND METHODS OF USE THEREOF

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2610356T3 (es) * 2009-02-03 2017-04-27 Amunix Operating Inc. Polipéptidos recombinantes extendidos y composiciones que comprenden los mismos
EP2473850B1 (en) * 2009-09-02 2015-05-13 Merck Serono S.A. Method of predicting the level of growth response
CN104519903A (zh) * 2012-06-05 2015-04-15 阿穆尼克斯运营公司 Hgh-xten融合蛋白及其在治疗生长激素缺乏中的用途

Also Published As

Publication number Publication date
WO2014164568A1 (en) 2014-10-09
SG11201506732YA (en) 2015-09-29
EP2968451A4 (en) 2017-01-04
EP2968451A1 (en) 2016-01-20
AU2014249258A1 (en) 2015-08-27
KR20150124955A (ko) 2015-11-06
US20160158321A1 (en) 2016-06-09
CN105209055A (zh) 2015-12-30
MX2015012175A (es) 2016-01-12
CA2900949A1 (en) 2014-10-09
JP2017101074A (ja) 2017-06-08
BR112015022257A2 (pt) 2017-10-10
IL240392A0 (en) 2015-09-24
JP2016514132A (ja) 2016-05-19
EA201591529A1 (ru) 2016-04-29
JP2019056013A (ja) 2019-04-11
CL2015002456A1 (es) 2016-05-27
PH12015502063A1 (en) 2016-01-25
BR112015022257A8 (pt) 2018-01-23

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