BR112015005794A2 - métodos para aumentar a funcionalidade do cérebro usando 2-fucosil-lactose - Google Patents
métodos para aumentar a funcionalidade do cérebro usando 2-fucosil-lactoseInfo
- Publication number
- BR112015005794A2 BR112015005794A2 BR112015005794A BR112015005794A BR112015005794A2 BR 112015005794 A2 BR112015005794 A2 BR 112015005794A2 BR 112015005794 A BR112015005794 A BR 112015005794A BR 112015005794 A BR112015005794 A BR 112015005794A BR 112015005794 A2 BR112015005794 A2 BR 112015005794A2
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- fucosyl
- lactose
- brain functionality
- fucosyl lactose
- Prior art date
Links
- HWHQUWQCBPAQQH-BWRPKUOHSA-N 2-fucosyllactose Chemical compound O[C@H]1[C@H](O)[C@H](O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@H]([C@H](O)CO)[C@H](O)[C@@H](O)C=O HWHQUWQCBPAQQH-BWRPKUOHSA-N 0.000 title abstract 3
- 210000004556 brain Anatomy 0.000 title abstract 2
- 210000001320 hippocampus Anatomy 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 230000027928 long-term synaptic potentiation Effects 0.000 abstract 1
- 230000014759 maintenance of location Effects 0.000 abstract 1
- 230000001537 neural effect Effects 0.000 abstract 1
- 210000000225 synapse Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pediatric Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
resumo métodos para aumentar a funcionalidade do cérebro usando 2-fucosil-lactose são divulgados métodos para melhorar a aprendizagem e/ou memória, melhorar a aquisição de memória, retenção e recuperação da memória pela indução de uma potenciação maior a longo prazo na sinapse neuronal no hipocampo nos indivíduos. os métodos incluem a administração de 2-fucosil-lactose a um indivíduo.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12382356.9A EP2708147B1 (en) | 2012-09-14 | 2012-09-14 | Methods for increasing brain functionality using 2-fucosyl-lactose |
PCT/US2013/059488 WO2014043368A1 (en) | 2012-09-14 | 2013-09-12 | Methods for increasing brain functionality using 2-fucosyl-lactose |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112015005794A2 true BR112015005794A2 (pt) | 2017-07-04 |
Family
ID=46940437
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112015005794A BR112015005794A2 (pt) | 2012-09-14 | 2013-09-12 | métodos para aumentar a funcionalidade do cérebro usando 2-fucosil-lactose |
Country Status (13)
Country | Link |
---|---|
US (1) | US10398715B2 (pt) |
EP (2) | EP3704957A1 (pt) |
CN (1) | CN104780785A (pt) |
BR (1) | BR112015005794A2 (pt) |
CA (1) | CA2884634A1 (pt) |
DK (1) | DK2708147T3 (pt) |
ES (1) | ES2795665T3 (pt) |
IL (1) | IL237617A0 (pt) |
MX (2) | MX2015003425A (pt) |
MY (1) | MY180148A (pt) |
PH (1) | PH12015500546A1 (pt) |
SG (1) | SG11201501893XA (pt) |
WO (1) | WO2014043368A1 (pt) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK2708145T3 (en) | 2012-09-14 | 2016-07-18 | Abbott Lab | Nutritional Compositions for Use in Methods to Modulate Corticosterone Levels in Psychologically Stressed Individuals |
EP2888950A1 (en) * | 2013-12-24 | 2015-07-01 | Abbott Laboratories | Methods for treating, preventing, or reducing neuroinflammation or cognitive impairment |
CN106998774A (zh) * | 2014-11-26 | 2017-08-01 | 雅培制药有限公司 | 包含人乳低聚糖、多不饱和脂肪酸、核苷酸以及叶黄素的婴儿配方 |
CN106998775A (zh) * | 2014-11-26 | 2017-08-01 | 雅培制药有限公司 | 具有RRR‑α‑生育酚、2’‑岩藻糖基乳糖和益生菌的婴儿配方 |
ES2927009T3 (es) | 2015-10-28 | 2022-10-31 | Glycom As | Composición sintética y método para modular la función cerebral y la conducta |
WO2017071716A1 (en) | 2015-10-28 | 2017-05-04 | Glycom A/S | Synthetic composition and method for modulating emotion and mood disorders |
KR101731263B1 (ko) | 2016-04-25 | 2017-05-02 | 서울대학교 산학협력단 | 코리네박테리움 글루타미쿰을 이용한 2'-푸코실락토오스의 생산방법 |
WO2017215722A1 (en) * | 2016-06-15 | 2017-12-21 | Glycom A/S | Synthetic composition comprising hmo and method for modulating emotion and mood disorders |
RU2019105567A (ru) | 2016-07-28 | 2020-08-28 | Фонтерра Ко-Оперэйтив Груп Лимитед | Молочный продукт и способ |
AU2018274637A1 (en) * | 2017-05-24 | 2019-09-26 | Societe Des Produits Nestle S.A. | Composition comprising oligofructose (OF) for use in the improvement of short term memory and other cognitive benefits |
US11026444B2 (en) | 2017-05-24 | 2021-06-08 | Societe Des Produits Nestle S.A. | Composition comprising human milk oligosaccharides (HMO) for use in the improvement of short term memory and other cognitive benefits |
EP3629768A1 (en) * | 2017-05-24 | 2020-04-08 | Société des Produits Nestlé S.A. | A nutritional composition for use to enhance attention and/or reduce impulsivity |
KR101953375B1 (ko) * | 2017-11-20 | 2019-02-28 | 고려대학교 산학협력단 | 다양하고 신규한 퓨코실 올리고당의 제조법 및 이의 용도 |
KR20190130720A (ko) * | 2018-05-15 | 2019-11-25 | (주)에이피테크놀로지 | 2'-푸코실락토오스를 포함하는 뇌졸중 예방용 조성물 |
BR112021016924A2 (pt) * | 2019-03-05 | 2021-11-03 | Glycom As | Oligossacarídeos do leite humano para uso no aprimoramento da função executiva |
CN116437820A (zh) | 2020-12-04 | 2023-07-14 | 雀巢产品有限公司 | 用于早产儿以促进早期出生后生长的稳定含水组合物 |
CN114223723A (zh) * | 2021-12-13 | 2022-03-25 | 黑龙江飞鹤乳业有限公司 | 营养组合物、包含其的食品以及该营养组合物的用途 |
KR102570073B1 (ko) * | 2022-11-17 | 2023-08-24 | (주)에이피테크놀로지 | 2'-푸코실락토오스를 포함하는 치매 개선 또는 치료용조성물 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0749492A1 (en) * | 1994-03-09 | 1996-12-27 | Abbott Laboratories | Humanized milk |
WO1996009299A1 (en) * | 1994-09-20 | 1996-03-28 | The Regents Of The University Of California | Drugs to improved synaptic transmission |
PT1039892E (pt) | 1997-02-21 | 2004-09-30 | Abbott Lab | Utilizacao de acidos gordos polinsaturados para reducao da incidencia de enterocolite necrotizante |
US6365218B1 (en) | 2000-02-04 | 2002-04-02 | Abbott Laboratories | Pediatric formula and methods for providing nutrition and improving tolerance |
US6811801B2 (en) | 2001-12-12 | 2004-11-02 | Abbott Laboratories | Methods and compositions for brightening the color of thermally processed nutritionals |
EP2173369A2 (en) * | 2003-08-08 | 2010-04-14 | DSM IP Assets B.V. | Novel method for screening brain-active compounds |
US7897637B2 (en) | 2006-07-19 | 2011-03-01 | The Salk Institute For Biological Studies | Methods of using flavonoids to enhance memory |
BRPI0921617A2 (pt) * | 2008-11-03 | 2015-08-18 | Nestec Sa | Composicao nutricional compreendendo probioticos e padroes do sono aperfeicoados |
CN102459294A (zh) * | 2009-04-07 | 2012-05-16 | 格礼卡姆股份公司 | 2’-o-岩藻糖基乳糖的合成 |
ES2651067T3 (es) | 2009-07-06 | 2018-01-24 | Children's Hospital Medical Center | Inhibición de la inflamación con oligosacáridos de la leche |
WO2012092159A1 (en) | 2010-12-31 | 2012-07-05 | Abbott Laboratories | Methods for reducing the incidence of oxidative stress using human milk oligosaccharides, vitamin c and anti-inflammatory agents |
US20120171166A1 (en) * | 2010-12-31 | 2012-07-05 | Abbott Laboratories | Synbiotic combination of probiotic and human milk oligosaccharides to promote growth of beneficial microbiota |
WO2012092156A1 (en) * | 2010-12-31 | 2012-07-05 | Abbott Laboratories | Methods for decreasing the incidence of necrotizing enterocolitis in infants, toddlers, or children using human milk oligosaccharides |
MY192208A (en) * | 2010-12-31 | 2022-08-08 | Abbott Lab | Nutritional formulations including human milk oligosaccharides and antioxidants and uses thereof |
CA3167205A1 (en) * | 2010-12-31 | 2012-07-05 | Abbott Laboratories | Human milk oligosaccharides to promote growth of beneficial bacteria |
SG10202110503VA (en) * | 2010-12-31 | 2021-11-29 | Abbott Lab | Human milk oligosaccharides for modulating inflammation |
PT2775852T (pt) | 2011-10-18 | 2016-11-08 | Nestec Sa | Composição para utilização no crescimento cerebral e/ou desenvolvimento cognitivo e/ou psicomotor |
DK2708145T3 (en) | 2012-09-14 | 2016-07-18 | Abbott Lab | Nutritional Compositions for Use in Methods to Modulate Corticosterone Levels in Psychologically Stressed Individuals |
-
2012
- 2012-09-14 DK DK12382356.9T patent/DK2708147T3/da active
- 2012-09-14 EP EP20161856.8A patent/EP3704957A1/en active Pending
- 2012-09-14 EP EP12382356.9A patent/EP2708147B1/en not_active Revoked
- 2012-09-14 ES ES12382356T patent/ES2795665T3/es active Active
-
2013
- 2013-09-12 MX MX2015003425A patent/MX2015003425A/es unknown
- 2013-09-12 US US14/428,247 patent/US10398715B2/en active Active
- 2013-09-12 CN CN201380059274.1A patent/CN104780785A/zh active Pending
- 2013-09-12 CA CA2884634A patent/CA2884634A1/en not_active Abandoned
- 2013-09-12 MY MYPI2015000615A patent/MY180148A/en unknown
- 2013-09-12 WO PCT/US2013/059488 patent/WO2014043368A1/en active Application Filing
- 2013-09-12 BR BR112015005794A patent/BR112015005794A2/pt not_active IP Right Cessation
- 2013-09-12 SG SG11201501893XA patent/SG11201501893XA/en unknown
-
2015
- 2015-03-08 IL IL237617A patent/IL237617A0/en unknown
- 2015-03-13 PH PH12015500546A patent/PH12015500546A1/en unknown
- 2015-03-13 MX MX2021010492A patent/MX2021010492A/es unknown
Also Published As
Publication number | Publication date |
---|---|
MX2015003425A (es) | 2015-06-22 |
EP3704957A1 (en) | 2020-09-09 |
EP2708147A1 (en) | 2014-03-19 |
US20150231159A1 (en) | 2015-08-20 |
EP2708147A8 (en) | 2014-09-03 |
SG11201501893XA (en) | 2015-04-29 |
DK2708147T3 (da) | 2020-05-18 |
WO2014043368A1 (en) | 2014-03-20 |
IL237617A0 (en) | 2015-04-30 |
MX2021010492A (es) | 2021-10-01 |
MY180148A (en) | 2020-11-23 |
CA2884634A1 (en) | 2014-03-20 |
US10398715B2 (en) | 2019-09-03 |
CN104780785A (zh) | 2015-07-15 |
PH12015500546A1 (en) | 2015-05-11 |
EP2708147B1 (en) | 2020-03-11 |
ES2795665T3 (es) | 2020-11-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |