BR112015002091A2 - método para a produção de um polipeptídeo, polipeptídeo, uso de um polipeptídeo e composição - Google Patents
método para a produção de um polipeptídeo, polipeptídeo, uso de um polipeptídeo e composiçãoInfo
- Publication number
- BR112015002091A2 BR112015002091A2 BR112015002091A BR112015002091A BR112015002091A2 BR 112015002091 A2 BR112015002091 A2 BR 112015002091A2 BR 112015002091 A BR112015002091 A BR 112015002091A BR 112015002091 A BR112015002091 A BR 112015002091A BR 112015002091 A2 BR112015002091 A2 BR 112015002091A2
- Authority
- BR
- Brazil
- Prior art keywords
- polypeptide
- producing
- composition
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title 3
- 102000004196 processed proteins & peptides Human genes 0.000 title 3
- 108090000765 processed proteins & peptides Proteins 0.000 title 3
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/525—Tumour necrosis factor [TNF]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/71—Decreased effector function due to an Fc-modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12179021 | 2012-08-02 | ||
| PCT/EP2013/066096 WO2014020069A1 (en) | 2012-08-02 | 2013-07-31 | Method for producing monomeric and multimeric molecules and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112015002091A2 true BR112015002091A2 (pt) | 2017-12-12 |
Family
ID=48914281
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112015002091A BR112015002091A2 (pt) | 2012-08-02 | 2013-07-31 | método para a produção de um polipeptídeo, polipeptídeo, uso de um polipeptídeo e composição |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US20150218250A1 (pt) |
| EP (1) | EP2880169B1 (pt) |
| JP (1) | JP6388581B2 (pt) |
| KR (1) | KR20150037959A (pt) |
| CN (1) | CN104508133B (pt) |
| BR (1) | BR112015002091A2 (pt) |
| CA (1) | CA2876099A1 (pt) |
| ES (1) | ES2633894T3 (pt) |
| HK (1) | HK1208880A1 (pt) |
| MX (1) | MX2015000683A (pt) |
| RU (1) | RU2015106812A (pt) |
| SG (1) | SG11201408530YA (pt) |
| WO (1) | WO2014020069A1 (pt) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6851200B2 (ja) | 2014-03-05 | 2021-03-31 | ユーシービー バイオファルマ エスアールエル | 多量体Ｆｃタンパク質 |
| KR102455680B1 (ko) * | 2014-07-15 | 2022-10-17 | 아스텔라스세이야쿠 가부시키가이샤 | 신규 항인간 Tie2 항체 |
| AR102522A1 (es) * | 2014-11-06 | 2017-03-08 | Hoffmann La Roche | Variantes de región fc con propiedades modificadas de unión a fcrn y proteína a |
| US11566082B2 (en) | 2014-11-17 | 2023-01-31 | Cytiva Bioprocess R&D Ab | Mutated immunoglobulin-binding polypeptides |
| US10730908B2 (en) | 2016-05-11 | 2020-08-04 | Ge Healthcare Bioprocess R&D Ab | Separation method |
| US10889615B2 (en) | 2016-05-11 | 2021-01-12 | Cytiva Bioprocess R&D Ab | Mutated immunoglobulin-binding polypeptides |
| US10654887B2 (en) | 2016-05-11 | 2020-05-19 | Ge Healthcare Bio-Process R&D Ab | Separation matrix |
| CN109311949B (zh) | 2016-05-11 | 2022-09-16 | 思拓凡生物工艺研发有限公司 | 储存分离基质的方法 |
| ES2909833T3 (es) | 2016-05-11 | 2022-05-10 | Cytiva Bioprocess R & D Ab | Método de limpieza y/o desinfección de una matriz de separación |
| US10703774B2 (en) | 2016-09-30 | 2020-07-07 | Ge Healthcare Bioprocess R&D Ab | Separation method |
| ES2874974T3 (es) | 2016-05-11 | 2021-11-05 | Cytiva Bioprocess R & D Ab | Matriz de separación |
| US11904082B2 (en) * | 2016-08-01 | 2024-02-20 | Kaneka Corporation | Adsorbent for calciprotein particles, adsorption removal system, and method for utilization thereof |
| US10696722B2 (en) | 2016-08-10 | 2020-06-30 | Ajou University Industry-Academic Cooperation Foundation | Heterodimeric Fc-fused cytokine and pharmaceutical composition comprising the same |
| CA3043630A1 (en) * | 2016-12-22 | 2018-06-28 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
| US20200277350A1 (en) * | 2017-09-25 | 2020-09-03 | Dingfu Biotarget Co., Ltd. | Proteinaceous heterodimer and use thereof |
| CN112585165A (zh) | 2018-04-25 | 2021-03-30 | 普罗米修斯生物科学公司 | 优化的抗tl1a抗体 |
| BR112021007175A2 (pt) | 2018-10-23 | 2021-08-10 | Dragonfly Therapeutics, Inc. | proteínas fundidas a fc heterodimérico |
| CN114901311A (zh) | 2019-10-24 | 2022-08-12 | 普罗米修斯生物科学公司 | Tnf样配体1a（tl1a）的人源化抗体及其用途 |
| EP4199953A1 (en) | 2020-08-19 | 2023-06-28 | Janssen Biotech, Inc. | Materials and methods of using engineered ligands |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4105480A1 (de) * | 1991-02-21 | 1992-08-27 | Boehringer Mannheim Gmbh | Verbesserte aktivierung von rekombinanten proteinen |
| US6284236B1 (en) * | 1995-06-29 | 2001-09-04 | Immunex Corporation | Cytokine that induces apoptosis |
| JP2002505086A (ja) | 1998-02-25 | 2002-02-19 | レキシジェン ファーマシューティカルズ コーポレイション | 抗体ベースの融合タンパク質の循環半減期の増強 |
| CA2338000C (en) | 1998-07-17 | 2009-12-15 | The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Water-soluble 4-thio-maleimido derivatives and methods for their production |
| SK9432001A3 (en) * | 1999-01-07 | 2003-02-04 | Lexigen Pharm Corp | Expression and export of anti-obesity proteins as Fc fusion proteins |
| US6737056B1 (en) * | 1999-01-15 | 2004-05-18 | Genentech, Inc. | Polypeptide variants with altered effector function |
| EP1200124B1 (en) * | 1999-07-13 | 2008-09-10 | Bolder Biotechnology, Inc. | Erythropoietin-immunoglobulin fusion proteins |
| ES2269366T3 (es) | 2000-02-11 | 2007-04-01 | Merck Patent Gmbh | Mejoramiento de la vida media en circulacion de proteinas de fusion basadas en anticuerpos. |
| CA2438094C (en) | 2001-02-23 | 2011-10-11 | Immunex Corporation | Increased recovery of active proteins |
| AU2002333502A1 (en) * | 2002-02-10 | 2003-09-04 | Apoxis Sa | Fusion constructs containing active sections of tnf ligands |
| CA2652570A1 (en) * | 2006-05-15 | 2007-11-22 | Viral Logic Systems Technology Corp. | Cd47 related compositions and methods for treating immunological diseases and disorders |
| AT505262A1 (de) | 2007-06-12 | 2008-12-15 | Apeiron Biolog Forschungs Und | Rekombinantes ace2 polypeptid |
| EP2365979A2 (en) | 2008-10-22 | 2011-09-21 | Biogen Idec MA Inc. | Recombinant fcrn and variants thereof for purification of fc-containing fusion proteins |
| EP2184070A1 (en) | 2008-11-07 | 2010-05-12 | Hla-G Technologies | HLA-G proteins and pharmaceutical uses thereof |
| PT2691417T (pt) * | 2011-03-29 | 2018-10-31 | Roche Glycart Ag | Variantes de fc de anticorpos |
| WO2012146630A1 (en) * | 2011-04-29 | 2012-11-01 | F. Hoffmann-La Roche Ag | N-terminal acylated polypeptides, methods for their production and uses thereof |
-
2013
- 2013-07-31 MX MX2015000683A patent/MX2015000683A/es unknown
- 2013-07-31 WO PCT/EP2013/066096 patent/WO2014020069A1/en active Application Filing
- 2013-07-31 CA CA2876099A patent/CA2876099A1/en not_active Abandoned
- 2013-07-31 RU RU2015106812A patent/RU2015106812A/ru not_active Application Discontinuation
- 2013-07-31 CN CN201380040175.9A patent/CN104508133B/zh active Active
- 2013-07-31 KR KR1020157002700A patent/KR20150037959A/ko not_active Application Discontinuation
- 2013-07-31 JP JP2015524776A patent/JP6388581B2/ja active Active
- 2013-07-31 EP EP13744530.0A patent/EP2880169B1/en active Active
- 2013-07-31 ES ES13744530.0T patent/ES2633894T3/es active Active
- 2013-07-31 BR BR112015002091A patent/BR112015002091A2/pt not_active IP Right Cessation
- 2013-07-31 SG SG11201408530YA patent/SG11201408530YA/en unknown
-
2015
- 2015-02-02 US US14/611,566 patent/US20150218250A1/en not_active Abandoned
- 2015-09-29 HK HK15109566.8A patent/HK1208880A1/xx unknown
-
2017
- 2017-05-09 US US15/590,374 patent/US10570188B2/en active Active
-
2020
- 2020-01-30 US US16/777,138 patent/US11254728B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| MX2015000683A (es) | 2015-04-10 |
| CN104508133A (zh) | 2015-04-08 |
| RU2015106812A (ru) | 2016-09-27 |
| CN104508133B (zh) | 2018-04-20 |
| KR20150037959A (ko) | 2015-04-08 |
| WO2014020069A1 (en) | 2014-02-06 |
| ES2633894T3 (es) | 2017-09-25 |
| EP2880169B1 (en) | 2017-05-17 |
| US20200157183A1 (en) | 2020-05-21 |
| SG11201408530YA (en) | 2015-03-30 |
| CA2876099A1 (en) | 2014-02-06 |
| HK1208880A1 (en) | 2016-03-18 |
| US20150218250A1 (en) | 2015-08-06 |
| US20170342128A1 (en) | 2017-11-30 |
| US10570188B2 (en) | 2020-02-25 |
| JP6388581B2 (ja) | 2018-09-12 |
| US11254728B2 (en) | 2022-02-22 |
| EP2880169A1 (en) | 2015-06-10 |
| JP2015531591A (ja) | 2015-11-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112015002091A2 (pt) | método para a produção de um polipeptídeo, polipeptídeo, uso de um polipeptídeo e composição | |
| BR112014016047A2 (pt) | composição de compósito degradável, composição, e método de uso um compósito degradável | |
| BR112015007120A2 (pt) | anticorpo biespecífico, composição farmacêutica, uso, célula hospedeira e método de produção de um anticorpo | |
| BR112015006824A2 (pt) | anticorpo igg biespecífico, método para produzir um anticorpo igg biespecífico, anticorpo, composição farmacêutica e uso de um anticorpo igg biespecífico | |
| BR112014001346A2 (pt) | composto nanotransportador, método, composto farmacêutico e uso de um composto | |
| BR112013033811A2 (pt) | composição, método de preparação da composição, e, composto | |
| BR112014028755A2 (pt) | composição de argamassa de poliuretano, processo para preparação da composição de argamassa de poliuretano, e, uso de uma composição de argamassa de poliuretano. | |
| BR112014031262A2 (pt) | composições biocatalisadoras inovadoras e processos para uso. | |
| BR112014015562A8 (pt) | aerofólio e método para fabricar um aerofólio | |
| BR112014032193A2 (pt) | métodos de produção de anticorpos biespecíficos e de determinação de combinação, anticorpo biespecífico, formulação e uso de anticorpo biespecífico | |
| BR112014015046A2 (pt) | dispersão de microcápsula, método para produzir uma dispersão de microcápsula, microcápsula, e, uso de uma dispersão de microcápsulas | |
| BR112015000420A2 (pt) | composto, composição farmacêutica, e, uso de um composto | |
| BR112013020611A2 (pt) | método para produção de compostos quelato de aminoácido, compostos quelato de aminoácido e uso de compostos quelato de aminoácido | |
| CO6920293A2 (es) | Compuestos antibaterianos y método para su uso | |
| BR112015022347A2 (pt) | composição para vacinação, método para produzir uma composição para vacinação e uso de composição | |
| BR112014016635A2 (pt) | composto, composição, e, uso de um composto | |
| BR112014017445A2 (pt) | composição, uso de uma composição, corpo lignocelulósico, e, método para preparar uma composição | |
| BR112014026564A2 (pt) | formulação, uso de uma formulação, e, processo para a preparação de uma formulação | |
| BR112014026565A2 (pt) | formulação, uso de uma formulação, e, processo para produzir uma formulação | |
| BR112014009684A2 (pt) | processo para preparar polímeros, polímero e uso de polímeros | |
| BR112013032690A2 (pt) | método para produzir um composto, composto, e, uso do mesmo | |
| BR112013015085A2 (pt) | composição farmacêutica, método para preparar uma composição, e, uso de composição | |
| BR112014016736A8 (pt) | composto, composição farmacêutica, método para tratamento, uso de um composto e invenção | |
| BR112014026873A2 (pt) | método cosmético, composição cosmética e uso. | |
| BR112013010736A2 (pt) | método para preparar um laminado, e, uso de um laminado |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06I | Publication of requirement cancelled [chapter 6.9 patent gazette] |
Free format text: ANULADA A PUBLICACAO CODIGO 6.6.1 NA RPI NO 2462 DE 13/03/2018 POR TER SIDO INDEVIDA. |
|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2525 DE 28-05-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |
|
| B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
| B350 | Update of information on the portal [chapter 15.35 patent gazette] |