BR112015002060B1 - implante compreendendo um corpo básico e uma superfície funcional e seu processo de produção - Google Patents
implante compreendendo um corpo básico e uma superfície funcional e seu processo de produção Download PDFInfo
- Publication number
- BR112015002060B1 BR112015002060B1 BR112015002060A BR112015002060A BR112015002060B1 BR 112015002060 B1 BR112015002060 B1 BR 112015002060B1 BR 112015002060 A BR112015002060 A BR 112015002060A BR 112015002060 A BR112015002060 A BR 112015002060A BR 112015002060 B1 BR112015002060 B1 BR 112015002060B1
- Authority
- BR
- Brazil
- Prior art keywords
- fact
- process according
- feedstock
- bone
- implant
- Prior art date
Links
- 239000007943 implant Substances 0.000 title claims abstract description 17
- 238000004519 manufacturing process Methods 0.000 title abstract description 5
- 238000000034 method Methods 0.000 claims abstract description 36
- 210000000988 bone and bone Anatomy 0.000 claims abstract description 20
- 239000000919 ceramic Substances 0.000 claims abstract description 17
- 239000004033 plastic Substances 0.000 claims abstract description 10
- 229920003023 plastic Polymers 0.000 claims abstract description 10
- 239000000463 material Substances 0.000 claims description 20
- 239000000843 powder Substances 0.000 claims description 13
- 239000011230 binding agent Substances 0.000 claims description 11
- 239000000203 mixture Substances 0.000 claims description 10
- 238000005245 sintering Methods 0.000 claims description 9
- 238000001125 extrusion Methods 0.000 claims description 5
- 238000004512 die casting Methods 0.000 claims description 4
- 229910052581 Si3N4 Inorganic materials 0.000 claims description 3
- 238000000465 moulding Methods 0.000 claims description 3
- TWNQGVIAIRXVLR-UHFFFAOYSA-N oxo(oxoalumanyloxy)alumane Chemical compound O=[Al]O[Al]=O TWNQGVIAIRXVLR-UHFFFAOYSA-N 0.000 claims description 3
- RVTZCBVAJQQJTK-UHFFFAOYSA-N oxygen(2-);zirconium(4+) Chemical compound [O-2].[O-2].[Zr+4] RVTZCBVAJQQJTK-UHFFFAOYSA-N 0.000 claims description 3
- -1 polyethylene Polymers 0.000 claims description 3
- HQVNEWCFYHHQES-UHFFFAOYSA-N silicon nitride Chemical compound N12[Si]34N5[Si]62N3[Si]51N64 HQVNEWCFYHHQES-UHFFFAOYSA-N 0.000 claims description 3
- 229910001928 zirconium oxide Inorganic materials 0.000 claims description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 2
- 239000004698 Polyethylene Substances 0.000 claims description 2
- 239000004793 Polystyrene Substances 0.000 claims description 2
- 239000000853 adhesive Substances 0.000 claims description 2
- 230000001070 adhesive effect Effects 0.000 claims description 2
- 150000001722 carbon compounds Chemical class 0.000 claims description 2
- 229910002804 graphite Inorganic materials 0.000 claims description 2
- 239000010439 graphite Substances 0.000 claims description 2
- 229920000573 polyethylene Polymers 0.000 claims description 2
- 229920002223 polystyrene Polymers 0.000 claims description 2
- 238000001746 injection moulding Methods 0.000 claims 2
- 238000007493 shaping process Methods 0.000 claims 2
- 239000002245 particle Substances 0.000 claims 1
- 229940127554 medical product Drugs 0.000 abstract description 5
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000007787 solid Substances 0.000 description 5
- 239000011248 coating agent Substances 0.000 description 3
- 238000000576 coating method Methods 0.000 description 3
- 239000011148 porous material Substances 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 2
- 238000010348 incorporation Methods 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 239000002253 acid Substances 0.000 description 1
- 230000002421 anti-septic effect Effects 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 239000011162 core material Substances 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 238000000265 homogenisation Methods 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 239000011236 particulate material Substances 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 125000006850 spacer group Chemical group 0.000 description 1
- 238000004381 surface treatment Methods 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
- A61L27/443—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with carbon fillers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/10—Ceramics or glasses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/10—Ceramics or glasses
- A61L27/105—Ceramics or glasses containing Al2O3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/30—Inorganic materials
- A61L27/306—Other specific inorganic materials not covered by A61L27/303 - A61L27/32
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
- A61L27/446—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with other specific inorganic fillers other than those covered by A61L27/443 or A61L27/46
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B81—MICROSTRUCTURAL TECHNOLOGY
- B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
- B81C1/00—Manufacture or treatment of devices or systems in or on a substrate
- B81C1/00015—Manufacture or treatment of devices or systems in or on a substrate for manufacturing microsystems
- B81C1/00206—Processes for functionalising a surface, e.g. provide the surface with specific mechanical, chemical or biological properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00179—Ceramics or ceramic-like structures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/08—Methods for forming porous structures using a negative form which is filled and then removed by pyrolysis or dissolution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2420/00—Materials or methods for coatings medical devices
- A61L2420/04—Coatings containing a composite material such as inorganic/organic, i.e. material comprising different phases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Ceramic Engineering (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Materials Engineering (AREA)
- Composite Materials (AREA)
- Dispersion Chemistry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Manufacturing & Machinery (AREA)
- Molecular Biology (AREA)
- Microelectronics & Electronic Packaging (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
- Compositions Of Oxide Ceramics (AREA)
- Press-Shaping Or Shaping Using Conveyers (AREA)
- Powder Metallurgy (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102012213348 | 2012-07-30 | ||
| PCT/EP2013/065810 WO2014019954A1 (de) | 2012-07-30 | 2013-07-26 | Mehrkomponenten-fügen von plastischen zubereitungen zur herstellung von medizinprodukten mit funktioneller oberfläche |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112015002060A2 BR112015002060A2 (pt) | 2017-07-04 |
| BR112015002060B1 true BR112015002060B1 (pt) | 2020-05-05 |
Family
ID=48914252
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112015002060A BR112015002060B1 (pt) | 2012-07-30 | 2013-07-26 | implante compreendendo um corpo básico e uma superfície funcional e seu processo de produção |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9717824B2 (https=) |
| EP (1) | EP2879725B1 (https=) |
| JP (1) | JP6290208B2 (https=) |
| KR (1) | KR102230646B1 (https=) |
| CN (1) | CN104507508B (https=) |
| AU (1) | AU2013298687B2 (https=) |
| BR (1) | BR112015002060B1 (https=) |
| CA (1) | CA2880109A1 (https=) |
| DE (1) | DE102013214657A1 (https=) |
| RU (1) | RU2676758C2 (https=) |
| WO (1) | WO2014019954A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6290208B2 (ja) * | 2012-07-30 | 2018-03-07 | セラムテック ゲゼルシャフト ミット ベシュレンクテル ハフツングＣｅｒａｍＴｅｃ ＧｍｂＨ | 機能表面を有する医療製品を製造するための可塑性調剤の多成分接合系 |
| KR20170031167A (ko) * | 2014-07-09 | 2017-03-20 | 세람테크 게엠베하 | 다공성 후방 외부 표면을 갖는 전체적으로 세라믹인 관골구 |
| WO2016005235A1 (de) * | 2014-07-09 | 2016-01-14 | Ceramtec Gmbh | Vollkeramischer kniegelenksersatz mit poröser knochenzugewandter rückseite |
| DE102015212260A1 (de) * | 2014-07-09 | 2016-01-14 | Ceramtec Gmbh | Vollkeramische Oberflächenersatzprothese mit poröser Innenseite |
| WO2018087245A1 (de) * | 2016-11-09 | 2018-05-17 | Ceramtec Gmbh | Ringförmiges keramisches implantat |
| US20210282931A1 (en) * | 2018-05-07 | 2021-09-16 | Ceramtec Gmbh | Implant for use in a wear couple including a spherical wear partner |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0107476A3 (en) * | 1982-10-25 | 1985-01-02 | Calcitek, Inc. | Bone graft substitute |
| JPS6485644A (en) | 1987-09-28 | 1989-03-30 | Asahi Optical Co Ltd | Preparation of ceramics composite |
| WO1995032008A1 (en) * | 1994-05-24 | 1995-11-30 | Implico B.V. | A biomaterial and bone implant for bone repair and replacement |
| JPH09299472A (ja) * | 1996-05-10 | 1997-11-25 | Ngk Spark Plug Co Ltd | 生体インプラント材料及びその製造方法 |
| JPH11178913A (ja) * | 1997-12-22 | 1999-07-06 | Kyocera Corp | 生体補綴部材 |
| DE19945529A1 (de) | 1999-09-23 | 2001-04-05 | Anton Bohmann | Implantat zur funktionserhaltenden Rekonstruktion von Skelettdefekten und Verfahren für die Herstellung |
| JP2005278874A (ja) * | 2004-03-29 | 2005-10-13 | Kyocera Corp | 人工関節 |
| CA2649108A1 (en) * | 2006-04-11 | 2007-10-25 | Smith & Nephew, Inc. | Ceramic metal composite for orthopaedic implants |
| GB0618930D0 (en) * | 2006-09-26 | 2006-11-08 | Smith & Nephew | Medical implant |
| DE102007020471A1 (de) * | 2007-04-27 | 2008-11-06 | Ceramtec Ag Innovative Ceramic Engineering | Sinterformkörper |
| DE102008001402A1 (de) | 2008-04-28 | 2009-10-29 | Ceramtec Ag | Formkörper mit poröser Oberfläche und Verfahren zu seiner Herstellung |
| JP6290208B2 (ja) * | 2012-07-30 | 2018-03-07 | セラムテック ゲゼルシャフト ミット ベシュレンクテル ハフツングＣｅｒａｍＴｅｃ ＧｍｂＨ | 機能表面を有する医療製品を製造するための可塑性調剤の多成分接合系 |
-
2013
- 2013-07-26 JP JP2015524739A patent/JP6290208B2/ja active Active
- 2013-07-26 KR KR1020157005366A patent/KR102230646B1/ko not_active Expired - Fee Related
- 2013-07-26 RU RU2015106834A patent/RU2676758C2/ru active
- 2013-07-26 DE DE102013214657.4A patent/DE102013214657A1/de not_active Withdrawn
- 2013-07-26 CA CA2880109A patent/CA2880109A1/en not_active Abandoned
- 2013-07-26 AU AU2013298687A patent/AU2013298687B2/en not_active Expired - Fee Related
- 2013-07-26 CN CN201380040674.8A patent/CN104507508B/zh active Active
- 2013-07-26 BR BR112015002060A patent/BR112015002060B1/pt active IP Right Grant
- 2013-07-26 US US14/416,986 patent/US9717824B2/en active Active
- 2013-07-26 WO PCT/EP2013/065810 patent/WO2014019954A1/de not_active Ceased
- 2013-07-26 EP EP13744487.3A patent/EP2879725B1/de active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2013298687A1 (en) | 2015-03-12 |
| WO2014019954A1 (de) | 2014-02-06 |
| RU2676758C2 (ru) | 2019-01-11 |
| JP2015526170A (ja) | 2015-09-10 |
| CN104507508A (zh) | 2015-04-08 |
| BR112015002060A2 (pt) | 2017-07-04 |
| EP2879725B1 (de) | 2020-09-16 |
| US9717824B2 (en) | 2017-08-01 |
| JP6290208B2 (ja) | 2018-03-07 |
| DE102013214657A1 (de) | 2014-01-30 |
| RU2015106834A (ru) | 2016-09-20 |
| KR20150039216A (ko) | 2015-04-09 |
| US20150224228A1 (en) | 2015-08-13 |
| CN104507508B (zh) | 2019-06-04 |
| EP2879725A1 (de) | 2015-06-10 |
| AU2013298687B2 (en) | 2016-09-29 |
| KR102230646B1 (ko) | 2021-03-19 |
| CA2880109A1 (en) | 2014-02-06 |
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