BR112014030993A2 - formulações tópicas, respectivo uso e método para tratar infecção de pele ou ferida - Google Patents

formulações tópicas, respectivo uso e método para tratar infecção de pele ou ferida

Info

Publication number
BR112014030993A2
BR112014030993A2 BR112014030993A BR112014030993A BR112014030993A2 BR 112014030993 A2 BR112014030993 A2 BR 112014030993A2 BR 112014030993 A BR112014030993 A BR 112014030993A BR 112014030993 A BR112014030993 A BR 112014030993A BR 112014030993 A2 BR112014030993 A2 BR 112014030993A2
Authority
BR
Brazil
Prior art keywords
topical formulations
treating skin
wound infection
infection
wound
Prior art date
Application number
BR112014030993A
Other languages
English (en)
Inventor
Desai Nayan
Original Assignee
Dipexium Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dipexium Pharmaceuticals Inc filed Critical Dipexium Pharmaceuticals Inc
Publication of BR112014030993A2 publication Critical patent/BR112014030993A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/30—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests characterised by the surfactants
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/46—N-acyl derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Abstract

“formulações tópicas, respectivo uso e método para tratar infecção de pele ou ferida” resumo a invenção proporciona formulações tópicas quimica e fisicamente estáveis de pexiganana e métodos para preparar as mesmas. 1/1
BR112014030993A 2012-06-12 2013-06-10 formulações tópicas, respectivo uso e método para tratar infecção de pele ou ferida BR112014030993A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/494,295 US8530409B1 (en) 2012-06-12 2012-06-12 Stable pexiganan formulation
PCT/US2013/044957 WO2013188286A1 (en) 2012-06-12 2013-06-10 Stable pexiganan formulation

Publications (1)

Publication Number Publication Date
BR112014030993A2 true BR112014030993A2 (pt) 2017-06-27

Family

ID=49084089

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014030993A BR112014030993A2 (pt) 2012-06-12 2013-06-10 formulações tópicas, respectivo uso e método para tratar infecção de pele ou ferida

Country Status (27)

Country Link
US (2) US8530409B1 (pt)
EP (1) EP2858721B1 (pt)
JP (1) JP5876191B2 (pt)
KR (1) KR101622524B1 (pt)
CN (1) CN104602762B (pt)
AU (1) AU2013274561B2 (pt)
BR (1) BR112014030993A2 (pt)
CA (1) CA2876668C (pt)
CY (1) CY1118277T1 (pt)
DK (1) DK2858721T3 (pt)
EA (1) EA028002B1 (pt)
ES (1) ES2599395T3 (pt)
HK (1) HK1210078A1 (pt)
HR (1) HRP20161440T1 (pt)
HU (1) HUE030665T2 (pt)
IL (1) IL236151A (pt)
LT (1) LT2858721T (pt)
MX (1) MX345263B (pt)
NZ (1) NZ703176A (pt)
PL (1) PL2858721T3 (pt)
PT (1) PT2858721T (pt)
RS (1) RS55286B1 (pt)
SG (1) SG11201408055PA (pt)
SI (1) SI2858721T1 (pt)
SM (1) SMT201600411B (pt)
WO (1) WO2013188286A1 (pt)
ZA (1) ZA201500117B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8530409B1 (en) * 2012-06-12 2013-09-10 Dipexium Pharmaceuticals LLC Stable pexiganan formulation
GB201505393D0 (en) * 2015-03-30 2015-05-13 Secr Defence Antimicrobal peptide formulations
CN111925430B (zh) * 2020-08-18 2022-05-24 中国海洋大学 抗菌肽及其应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4144346A (en) * 1977-01-31 1979-03-13 Janssen Pharmaceutica N.V. Novel 1-(1,3-dioxolan-2-ylmethyl)-1H-imidazoles
US4169703A (en) * 1978-08-03 1979-10-02 Syntex (U.S.A.) Inc. Oxidative red hair dye
US5912231A (en) * 1989-07-07 1999-06-15 Scripps Clinic And Research Foundation Substitution analogues of magainin peptides
TW460296B (en) * 1994-09-01 2001-10-21 Janssen Pharmaceutica Nv Topical ketoconazole emulsion compositions without sodium sulfite
US7530461B2 (en) * 1995-03-10 2009-05-12 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
EP1734925A2 (en) * 2004-03-18 2006-12-27 Panacea Biotec Ltd. Novel compositions for topical delivery
US20080260655A1 (en) * 2006-11-14 2008-10-23 Dov Tamarkin Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
WO2009070564A2 (en) * 2007-11-27 2009-06-04 Macrochem Corporation Compositions and methods for prevention of infection in transcutaneous osseointegrated implants
US8318817B2 (en) * 2008-07-21 2012-11-27 Otonomy, Inc. Controlled release antimicrobial compositions and methods for the treatment of otic disorders
WO2012174373A1 (en) * 2011-06-16 2012-12-20 Dipexium Pharmaceuticals Methods of treating and inhibiting pathogens with resistance-mechanisms
US8530409B1 (en) * 2012-06-12 2013-09-10 Dipexium Pharmaceuticals LLC Stable pexiganan formulation

Also Published As

Publication number Publication date
AU2013274561A1 (en) 2015-01-22
AU2013274561B2 (en) 2015-09-10
CN104602762A (zh) 2015-05-06
HK1210078A1 (en) 2016-04-15
SG11201408055PA (en) 2015-01-29
CN104602762B (zh) 2017-04-05
CY1118277T1 (el) 2017-06-28
SMT201600411B (it) 2017-01-10
JP5876191B2 (ja) 2016-03-02
HRP20161440T1 (hr) 2016-12-16
KR20150043286A (ko) 2015-04-22
MX2014015199A (es) 2015-08-14
EP2858721A1 (en) 2015-04-15
DK2858721T3 (en) 2016-11-28
CA2876668A1 (en) 2013-12-19
EP2858721B1 (en) 2016-08-17
PL2858721T3 (pl) 2017-02-28
IL236151A0 (en) 2015-01-29
RS55286B1 (sr) 2017-03-31
ES2599395T3 (es) 2017-02-01
ZA201500117B (en) 2016-10-26
WO2013188286A1 (en) 2013-12-19
EA028002B1 (ru) 2017-09-29
IL236151A (en) 2016-06-30
JP2015521599A (ja) 2015-07-30
EA201492280A1 (ru) 2015-05-29
HUE030665T2 (en) 2017-05-29
KR101622524B1 (ko) 2016-05-18
MX345263B (es) 2017-01-23
EP2858721A4 (en) 2015-12-09
NZ703176A (en) 2015-08-28
SI2858721T1 (sl) 2017-01-31
CA2876668C (en) 2017-12-05
US20140038882A1 (en) 2014-02-06
LT2858721T (lt) 2016-12-12
US8530409B1 (en) 2013-09-10
PT2858721T (pt) 2016-11-17

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Legal Events

Date Code Title Description
B25G Requested change of headquarter approved

Owner name: DIPEXIUM PHARMACEUTICALS, INC. (US)

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06I Publication of requirement cancelled [chapter 6.9 patent gazette]

Free format text: ANULADA A PUBLICACAO CODIGO 6.6.1 NA RPI NO 2462 DE 13/03/2018 POR TER SIDO INDEVIDA.

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2517 DE 02-04-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.