BR112014029206A2 - pós hemostáticos de celulose regenerada oxidada e métodos para fabricação dos mesmos - Google Patents

pós hemostáticos de celulose regenerada oxidada e métodos para fabricação dos mesmos

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Publication number
BR112014029206A2
BR112014029206A2 BR112014029206A BR112014029206A BR112014029206A2 BR 112014029206 A2 BR112014029206 A2 BR 112014029206A2 BR 112014029206 A BR112014029206 A BR 112014029206A BR 112014029206 A BR112014029206 A BR 112014029206A BR 112014029206 A2 BR112014029206 A2 BR 112014029206A2
Authority
BR
Brazil
Prior art keywords
methods
manufacture
regenerated cellulose
orc
oxidized regenerated
Prior art date
Application number
BR112014029206A
Other languages
English (en)
Other versions
BR112014029206B1 (pt
Inventor
Zhang Guanghui
Wang Yi-Lan
Original Assignee
Ethicon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48537032&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112014029206(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ethicon Inc filed Critical Ethicon Inc
Priority to BR122019014998A priority Critical patent/BR122019014998B1/pt
Publication of BR112014029206A2 publication Critical patent/BR112014029206A2/pt
Publication of BR112014029206B1 publication Critical patent/BR112014029206B1/pt

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061Use of materials characterised by their function or physical properties
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/717Celluloses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/02Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of powders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0023Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061Use of materials characterised by their function or physical properties
    • A61L26/0066Medicaments; Biocides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061Use of materials characterised by their function or physical properties
    • A61L26/009Materials resorbable by the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L1/00Compositions of cellulose, modified cellulose or cellulose derivatives
    • C08L1/02Cellulose; Modified cellulose
    • C08L1/04Oxycellulose; Hydrocellulose, e.g. microcrystalline cellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404Biocides, antimicrobial agents, antiseptic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/418Agents promoting blood coagulation, blood-clotting agents, embolising agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/04Materials for stopping bleeding
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Polymers & Plastics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Surgical Instruments (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

resumo patente de invenção: "pós hemostáticos de celulose regenerada oxidada e métodos para fabricação dos mesmos". a presente invenção refere-se a um material hemostático contendo orc em pó compactada, que compreende partículas com uma razão de aspecto média de cerca de 1 a cerca de 18, sendo que a dita orc em pó compactada foi, de preferência, processada em um dispositivo de compactação, como uma orc em pó triturada em moinho de bolas. a presente invenção refere-se, adicionalmente, a métodos para fabricação de material hemostático e a um método para tratamento de uma ferida mediante a aplicação do pó hemostático sobre a e/ou dentro da ferida de um paciente. 23147616v1 1/1 23147616v1
BR112014029206A 2012-05-25 2013-05-22 material hemostático compreendendo de celulose regenerada oxidada, seu método de fabricação e pasta hemostática BR112014029206B1 (pt)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BR122019014998A BR122019014998B1 (pt) 2012-05-25 2013-05-22 pós hemostáticos de celulose regenerada oxidada e métodos para fabricação dos mesmos

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/480,842 US8815832B2 (en) 2012-05-25 2012-05-25 Oxidized regenerated cellulose hemostatic powders and methods of making
PCT/US2013/042149 WO2013177242A1 (en) 2012-05-25 2013-05-22 Oxidized regenerated cellulose hemostatic powders and methods of making

Publications (2)

Publication Number Publication Date
BR112014029206A2 true BR112014029206A2 (pt) 2017-06-27
BR112014029206B1 BR112014029206B1 (pt) 2019-11-26

Family

ID=48537032

Family Applications (2)

Application Number Title Priority Date Filing Date
BR112014029206A BR112014029206B1 (pt) 2012-05-25 2013-05-22 material hemostático compreendendo de celulose regenerada oxidada, seu método de fabricação e pasta hemostática
BR122019014998A BR122019014998B1 (pt) 2012-05-25 2013-05-22 pós hemostáticos de celulose regenerada oxidada e métodos para fabricação dos mesmos

Family Applications After (1)

Application Number Title Priority Date Filing Date
BR122019014998A BR122019014998B1 (pt) 2012-05-25 2013-05-22 pós hemostáticos de celulose regenerada oxidada e métodos para fabricação dos mesmos

Country Status (16)

Country Link
US (2) US8815832B2 (pt)
EP (3) EP3466455B1 (pt)
JP (1) JP6165849B2 (pt)
KR (2) KR102131601B1 (pt)
CN (1) CN104321085B (pt)
AU (1) AU2013266416B2 (pt)
BR (2) BR112014029206B1 (pt)
CA (2) CA3094664C (pt)
DK (1) DK3466455T3 (pt)
ES (2) ES2702714T3 (pt)
IL (2) IL235549B (pt)
IN (1) IN2014DN09514A (pt)
MX (2) MX354596B (pt)
RU (2) RU2629199C2 (pt)
WO (1) WO2013177242A1 (pt)
ZA (1) ZA201409429B (pt)

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Also Published As

Publication number Publication date
EP3466455A1 (en) 2019-04-10
JP6165849B2 (ja) 2017-07-19
BR122019014998B1 (pt) 2020-01-28
RU2017128652A (ru) 2019-02-04
AU2013266416B2 (en) 2016-03-24
KR20150015517A (ko) 2015-02-10
CA3094664A1 (en) 2013-11-28
CN104321085A (zh) 2015-01-28
IN2014DN09514A (pt) 2015-07-17
WO2013177242A1 (en) 2013-11-28
BR112014029206B1 (pt) 2019-11-26
ES2906971T3 (es) 2022-04-21
EP4043042A1 (en) 2022-08-17
EP2854882A1 (en) 2015-04-08
KR102131601B1 (ko) 2020-07-09
CA3094664C (en) 2023-06-06
IL235549B (en) 2020-03-31
JP2015517388A (ja) 2015-06-22
RU2014152706A (ru) 2016-07-20
AU2013266416A1 (en) 2014-11-27
EP2854882B1 (en) 2018-10-31
EP3466455B1 (en) 2022-01-19
IL261869A (en) 2018-10-31
CN104321085B (zh) 2017-06-23
KR20200085904A (ko) 2020-07-15
KR102254305B1 (ko) 2021-05-24
MX2014014322A (es) 2015-02-12
MX354596B (es) 2018-03-12
US20130316974A1 (en) 2013-11-28
ZA201409429B (en) 2017-04-26
CA2874622C (en) 2021-03-09
US8815832B2 (en) 2014-08-26
IL261869B (en) 2020-07-30
CA2874622A1 (en) 2013-11-28
RU2629199C2 (ru) 2017-08-25
IL235549A0 (en) 2015-01-29
RU2017128652A3 (pt) 2019-05-28
US20140329769A1 (en) 2014-11-06
MX358625B (es) 2018-08-28
RU2696575C2 (ru) 2019-08-05
US9539358B2 (en) 2017-01-10
ES2702714T3 (es) 2019-03-05
DK3466455T3 (da) 2022-03-14

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