BR112014027953A2 - nifuratel- (r), seu uso para o tratamento de infecções e síntese de nifuratel -(r) e -(s) - Google Patents

nifuratel- (r), seu uso para o tratamento de infecções e síntese de nifuratel -(r) e -(s)

Info

Publication number
BR112014027953A2
BR112014027953A2 BR112014027953A BR112014027953A BR112014027953A2 BR 112014027953 A2 BR112014027953 A2 BR 112014027953A2 BR 112014027953 A BR112014027953 A BR 112014027953A BR 112014027953 A BR112014027953 A BR 112014027953A BR 112014027953 A2 BR112014027953 A2 BR 112014027953A2
Authority
BR
Brazil
Prior art keywords
nifuratel
infections
synthesis
treatment
Prior art date
Application number
BR112014027953A
Other languages
English (en)
Inventor
Consonni Alessandra
Bulgheroni Anna
Mailland Federico
Gagliardi Stefania
Original Assignee
Polichem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47846051&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112014027953(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Polichem Sa filed Critical Polichem Sa
Publication of BR112014027953A2 publication Critical patent/BR112014027953A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C241/00—Preparation of compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C241/02—Preparation of hydrazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/26—Oxygen atoms attached in position 2 with hetero atoms or acyl radicals directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/422—Oxazoles not condensed and containing further heterocyclic rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
BR112014027953A 2012-05-11 2013-03-13 nifuratel- (r), seu uso para o tratamento de infecções e síntese de nifuratel -(r) e -(s) BR112014027953A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20120167640 EP2662371A1 (en) 2012-05-11 2012-05-11 (R)-Nifuratel and synthesis of (R) and (S)-Nifuratel
PCT/EP2013/055078 WO2013167295A1 (en) 2012-05-11 2013-03-13 (r) -nifuratel, its use for the treatment of infections and synthesis of (r) and (s) -nifuratel

Publications (1)

Publication Number Publication Date
BR112014027953A2 true BR112014027953A2 (pt) 2018-02-06

Family

ID=47846051

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014027953A BR112014027953A2 (pt) 2012-05-11 2013-03-13 nifuratel- (r), seu uso para o tratamento de infecções e síntese de nifuratel -(r) e -(s)

Country Status (27)

Country Link
US (2) US9284306B2 (pt)
EP (2) EP2662371A1 (pt)
JP (1) JP2015515998A (pt)
KR (1) KR20150008871A (pt)
CN (1) CN104379580A (pt)
AU (1) AU2013258385A1 (pt)
BR (1) BR112014027953A2 (pt)
CA (1) CA2869827A1 (pt)
CL (1) CL2014002951A1 (pt)
CO (1) CO7131368A2 (pt)
CR (1) CR20140505A (pt)
DO (1) DOP2014000252A (pt)
EA (1) EA201492081A1 (pt)
EC (1) ECSP14026432A (pt)
GE (2) GEP201606595B (pt)
HK (1) HK1202539A1 (pt)
IL (1) IL235429A0 (pt)
IN (1) IN2014DN09256A (pt)
MA (1) MA20150279A1 (pt)
MX (1) MX2014013759A (pt)
NZ (1) NZ700752A (pt)
PE (1) PE20150167A1 (pt)
PH (2) PH12014502500A1 (pt)
SG (2) SG10201608485XA (pt)
TN (1) TN2014000430A1 (pt)
WO (1) WO2013167295A1 (pt)
ZA (1) ZA201407596B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108254453A (zh) * 2016-12-28 2018-07-06 苏州电器科学研究院股份有限公司 一种有效测定塑料制品中邻苯二甲酸酯含量的检测方法
RU2020113749A (ru) 2017-09-20 2021-10-20 пиЭйч ФАРМА Ко., ЛТД. Аналоги таиланстатина
CN108760950B (zh) * 2018-04-25 2022-07-15 国检测试控股集团京诚检测有限公司 一种测定硝基呋喃代谢物的方法
CN111892557B (zh) * 2019-05-05 2022-11-08 河北圣泰材料股份有限公司 哌嗪类成膜离子液体的合成方法
CN110672765B (zh) * 2019-10-11 2022-03-18 温州海鹤药业有限公司 一种定量检测硝呋太尔中顺式异构体杂质的方法
CN112457304B (zh) * 2020-12-07 2022-03-11 中国药科大学 一种硝呋太尔的制备方法
CN113828243B (zh) * 2021-09-14 2022-06-28 南京南大药业有限责任公司 一种硝呋太尔制霉菌素栓制造方法及设备

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE635608A (pt) 1962-08-01
CN100506820C (zh) 2006-03-16 2009-07-01 韩志强 (s)-硝呋太尔,其制备方法和应用
CN100516063C (zh) * 2006-03-16 2009-07-22 韩志强 硝呋太尔的生产方法
CN101434584A (zh) * 2007-11-15 2009-05-20 中山大学 具有抗菌活性的手性噁唑烷酮类化合物
EP2243482A1 (en) * 2009-04-20 2010-10-27 Polichem SA Use of nifuratel to treat infections caused by atopobium species

Also Published As

Publication number Publication date
NZ700752A (en) 2016-02-26
PH12014502500B1 (en) 2014-12-15
CL2014002951A1 (es) 2014-12-26
CO7131368A2 (es) 2014-12-01
IN2014DN09256A (pt) 2015-07-10
WO2013167295A1 (en) 2013-11-14
EA201492081A1 (ru) 2015-06-30
CA2869827A1 (en) 2013-11-14
JP2015515998A (ja) 2015-06-04
AU2013258385A1 (en) 2014-10-30
SG10201608485XA (en) 2016-12-29
MA20150279A1 (fr) 2015-08-31
HK1202539A1 (en) 2015-10-02
US9284306B2 (en) 2016-03-15
IL235429A0 (en) 2014-12-31
PE20150167A1 (es) 2015-02-07
GEP201606595B (en) 2017-01-10
PH12015502241A1 (en) 2016-08-15
EP2662371A1 (en) 2013-11-13
CR20140505A (es) 2015-02-06
ECSP14026432A (es) 2015-09-30
CN104379580A (zh) 2015-02-25
ZA201407596B (en) 2016-05-25
GEP201706626B (en) 2017-02-10
PH12014502500A1 (en) 2014-12-15
SG11201406447SA (en) 2014-11-27
DOP2014000252A (es) 2014-12-31
US20150148547A1 (en) 2015-05-28
US9067927B2 (en) 2015-06-30
EP2847189A1 (en) 2015-03-18
TN2014000430A1 (en) 2016-03-30
MX2014013759A (es) 2015-08-07
KR20150008871A (ko) 2015-01-23
US20150119431A1 (en) 2015-04-30

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]